All Stories

  1. Model-Based Optimization of Microalgae Growth in a Batch Plant

    Article • Industrial & Engineering Chemistry Research, March 2019, American Chemical Society (ACS)

    Fabrizio Bezzo

  2. Meteorological Data-Based Optimal Control Strategy for Microalgae Cultivation in Open Pond Systems

    Article • Complexity, January 2019, Hindawi Publishing Corporation

    Fabrizio Bezzo

  3. Microalgae growth optimization in open ponds with uncertain weather data

    Article • Computers & Chemical Engineering, September 2018, Elsevier

    Fabrizio Bezzo

  4. Economic optimisation of European supply chains for CO 2 capture, transport and sequestration, including societal risk analysis and risk mitigation measures

    Article • Applied Energy, August 2018, Elsevier

    Fabrizio Bezzo

  5. A novel and systematic approach to identify the design space of pharmaceutical processes

    Article • Computers & Chemical Engineering, July 2018, Elsevier

    Fabrizio Bezzo

  6. Modelling the photosynthetic electron transport chain in Nannochloropsis gaditana via exploitation of absorbance data

    Article • Algal Research, July 2018, Elsevier

    Fabrizio Bezzo

  7. Probabilistic Design space determination in pharmaceutical product development: A Bayesian/latent variable approach

    Article • AIChE Journal, March 2018, Wiley

    Fabrizio Bezzo

  8. Assessing multiple biomass-feedstock in the optimization of power and fuel supply chains for sustainable mobility

    Article • Chemical Engineering Research and Design, March 2018, Elsevier

    Fabrizio Bezzo

  9. Mining Information From Developmental Data

    Article • January 2018, Elsevier

    Fabrizio Bezzo

  10. A Mechanistic Model to Quantify von Willebrand Factor Release, Survival and Proteolysis in Patients with von Willebrand Disease

    Article • Thrombosis and Haemostasis, January 2018, Thieme Publishing Group

    Fabrizio Bezzo

  11. Advanced Techniques for the Optimal Design of Experiments in Pharmacokinetics

    Article • January 2018, Elsevier

    Fabrizio Bezzo

  12. Dimensionality reduction in feasibility analysis by latent variable modeling

    Article • January 2018, Elsevier

    Fabrizio Bezzo

  13. On the Identifiability of Physiological Models: Optimal Design of Clinical Tests

    Article • January 2018, Elsevier

    Fabrizio Bezzo

  14. Towards the economic optimisation of European supply chains for CO 2 capture, transport and sequestration, including societal risk analysis

    Article • January 2018, Elsevier

    Fabrizio Bezzo

  15. Towards the optimal design of a minimum set of clinical trials for the identification and characterization of VWD

    Article • January 2018, Elsevier

    Fabrizio Bezzo

  16. A mathematical model to guide genetic engineering of photosynthetic metabolism

    Article • Metabolic Engineering, November 2017, Elsevier

    Fabrizio Bezzo

  17. Managing technology performance risk in the strategic design of biomass-based supply chains for energy in the transport sector

    Article • Energy, November 2017, Elsevier

    Fabrizio Bezzo

  18. Model-based approach to the design and scale-up of wheat milling operations — Proof of concept

    Article • Food and Bioproducts Processing, November 2017, Elsevier

    Fabrizio Bezzo

  19. A model-based protocol for the diagnosis of von Willebrand disease

    Article • The Canadian Journal of Chemical Engineering, October 2017, Wiley

    Fabrizio Bezzo

  20. Economic optimisation of European supply chains for CO 2 capture, transport and sequestration

    Article • International Journal of Greenhouse Gas Control, October 2017, Elsevier

    Fabrizio Bezzo

  21. Semi-empirical modeling of microalgae photosynthesis in different acclimation states – Application to N. gaditana

    Article • Journal of Biotechnology, October 2017, Elsevier

    Fabrizio Bezzo

  22. Exploiting meteorological forecasts for the optimal operation of algal ponds

    Article • Journal of Process Control, July 2017, Elsevier

    Fabrizio Bezzo

  23. Uncertainty back-propagation in PLS model inversion for design space determination in pharmaceutical product development

    Article • Computers & Chemical Engineering, June 2017, Elsevier

    Fabrizio Bezzo

  24. Assessing the relative potency of (S)- and (R)-warfarin with a new PK-PD model, in relation to VKORC1 genotypes

    Article • European Journal of Clinical Pharmacology, April 2017, Springer Science + Business Media

    Fabrizio Bezzo

  25. A Model-Based Support for Diagnosing von Willebrand Disease

    Article • January 2017, Elsevier

    Fabrizio Bezzo

  26. Assessing Technological Options in Biomass-Based Energy Supply Chains through a Quantitative Methodology for Risk and Regret Evaluation

    Article • January 2017, Elsevier

    Fabrizio Bezzo

  27. Novel micro-photobioreactor design and monitoring method for assessing microalgae response to light intensity

    Article • Algal Research, November 2016, Elsevier

    Fabrizio Bezzo

  28. A methodology for direct exploitation of available information in the online model-based redesign of experiments

    Article • Computers & Chemical Engineering, August 2016, Elsevier

    Fabrizio Bezzo

  29. Data-driven modeling of milling and sieving operations in a wheat milling process

    Article • Food and Bioproducts Processing, July 2016, Elsevier

    Fabrizio Bezzo

  30. Correction: High-Fidelity Modelling Methodology of Light-Limited Photosynthetic Production in Microalgae

    Article • PLoS ONE, June 2016, PLOS

    Fabrizio Bezzo

  31. Knowledge management in secondary pharmaceutical manufacturing by mining of data historians—A proof-of-concept study

    Article • International Journal of Pharmaceutics, May 2016, Elsevier

    Fabrizio Bezzo

  32. High-Fidelity Modelling Methodology of Light-Limited Photosynthetic Production in Microalgae

    Article • PLoS ONE, April 2016, PLOS

    Fabrizio Bezzo

  33. Strategic optimisation of biomass-based energy supply chains for sustainable mobility

    Article • Computers & Chemical Engineering, April 2016, Elsevier

    Fabrizio Bezzo

  34. A model-based investigation of genetically modified microalgae strains

    Article • January 2016, Elsevier

    Fabrizio Bezzo

  35. A pharmacokinetic-pharmacodynamic model for individualisation of an oral anticoagulation therapy

    Article • January 2016, Elsevier

    Fabrizio Bezzo

  36. A two-tier approach to the optimization of a biomass supply chain for pyrolysis processes

    Article • Biomass and Bioenergy, January 2016, Elsevier

    Fabrizio Bezzo

  37. Automated Data Review in Secondary Pharmaceutical Manufacturing by Pattern Recognition Techniques

    Article • January 2016, Elsevier

    Fabrizio Bezzo

  38. Optimal design of experiments for parameter identification in electrodialysis models

    Article • Chemical Engineering Research and Design, January 2016, Elsevier

    Fabrizio Bezzo

  39. Optimal operation of algal ponds accounting for future meteorology

    Article • IFAC-PapersOnLine, January 2016, Elsevier

    Fabrizio Bezzo

  40. Optimising biomass-based energy supply chains for sustainable mobility

    Article • January 2016, Elsevier

    Fabrizio Bezzo

  41. Using PLS and NIR spectra to model the first-breakage step of a grain milling process

    Article • January 2016, Elsevier

    Fabrizio Bezzo

  42. Quality-by-Design approach to monitor the operation of a batch bioreactor in an industrial avian vaccine manufacturing process

    Article • Journal of Biotechnology, October 2015, Elsevier

    Fabrizio Bezzo

  43. Phase identification for product quality prediction in batch processes: Application to industrial resin production

    Article • July 2015, Institute of Electrical & Electronics Engineers (IEEE)

    Fabrizio Bezzo

  44. Bracketing the Design Space within the Knowledge Space in Pharmaceutical Product Development

    Article • Industrial & Engineering Chemistry Research, April 2015, American Chemical Society (ACS)

    Fabrizio Bezzo

  45. A Framework for the Dynamic Modelling of PI Curves in Microalgae

    Article • January 2015, Elsevier

    Fabrizio Bezzo

  46. A model of chlorophyll fluorescence in microalgae integrating photoproduction, photoinhibition and photoregulation

    Article • Journal of Biotechnology, January 2015, Elsevier

    Fabrizio Bezzo

  47. An approach to optimize multi-enterprise biofuel supply chains including Nash equilibrium models

    Article • January 2015, Elsevier

    Fabrizio Bezzo

  48. Bioethanol Supply Chain Design and Optimization

    Article • January 2015, Elsevier

    Fabrizio Bezzo

  49. Data-based multivariate modeling of a grain comminution process

    Article • January 2015, Elsevier

    Fabrizio Bezzo

  50. First-Principles Model Diagnosis in Batch Systems by Multivariate Statistical Modeling

    Article • January 2015, Elsevier

    Fabrizio Bezzo

  51. Impact on the optimal design of bioethanol supply chains by a new European Commission proposal

    Article • Chemical Engineering Research and Design, January 2015, Elsevier

    Fabrizio Bezzo

  52. A Methodology to Diagnose Process/Model Mismatch in First-Principles Models

    Article • Industrial & Engineering Chemistry Research, August 2014, American Chemical Society (ACS)

    Fabrizio Bezzo

  53. Identification of Physiological Models of Type 1 Diabetes Mellitus by Model-Based Design of Experiments

    Article • June 2014, Wiley

    Fabrizio Bezzo

  54. An Identifiable State Model To Describe Light Intensity Influence on Microalgae Growth

    Article • Industrial & Engineering Chemistry Research, April 2014, American Chemical Society (ACS)

    Fabrizio Bezzo

  55. A model-based approach to the automatic diagnosis of von Willebrand disease

    Article • AIChE Journal, February 2014, Wiley

    Fabrizio Bezzo

  56. Transfer of process monitoring models between plants: Batch systems

    Article • Chemical Engineering Research and Design, February 2014, Elsevier

    Fabrizio Bezzo

  57. Bacterial inactivation on solid food matrices through supercritical CO2: A correlative study

    Article • Journal of Food Engineering, January 2014, Elsevier

    Fabrizio Bezzo

  58. Diagnosing Process/Model Mismatch in First-Principles Models by Latent Variable Modeling

    Article • January 2014, Elsevier

    Fabrizio Bezzo

  59. Optimal Design of a Bioethanol Supply Chain Considering Different Environmental Impact Assessment Methods

    Article • January 2014, Elsevier

    Fabrizio Bezzo

  60. Towards Model-Based Diagnosis of von Willebrand Disease

    Article • January 2014, Elsevier

    Fabrizio Bezzo

  61. A risk management approach to the economic and environmental strategic design of ethanol supply chains

    Article • Biomass and Bioenergy, November 2013, Elsevier

    Fabrizio Bezzo

  62. Latent variable modeling to assist the implementation of Quality-by-Design paradigms in pharmaceutical development and manufacturing: A review

    Article • International Journal of Pharmaceutics, November 2013, Elsevier

    Fabrizio Bezzo

  63. Transfer of a nanoparticle product between different mixers using latent variable model inversion

    Article • AIChE Journal, October 2013, Wiley

    Fabrizio Bezzo

  64. Strategic Design of Bioethanol Supply Chains Including Commodity Market Dynamics

    Article • Industrial & Engineering Chemistry Research, July 2013, American Chemical Society (ACS)

    Fabrizio Bezzo

  65. Optimal design of ethanol supply chains considering carbon trading effects and multiple technologies for side-product exploitation

    Article • Environmental Technology, July 2013, Taylor & Francis

    Fabrizio Bezzo

  66. Exploiting Historical Databases to Design the Target Quality Profile for a New Product

    Article • Industrial & Engineering Chemistry Research, June 2013, American Chemical Society (ACS)

    Fabrizio Bezzo

  67. A general model-based design of experiments approach to achieve practical identifiability of pharmacokinetic and pharmacodynamic models

    Article • Journal of Pharmacokinetics and Pharmacodynamics, June 2013, Springer Science + Business Media

    Fabrizio Bezzo

  68. General procedure to aid the development of continuous pharmaceutical processes using multivariate statistical modeling – An industrial case study

    Article • International Journal of Pharmaceutics, February 2013, Elsevier

    Fabrizio Bezzo

  69. On the use of continuous glucose monitoring systems to design optimal clinical tests for the identification of type 1 diabetes models

    Article • Computer Methods and Programs in Biomedicine, February 2013, Elsevier

    Fabrizio Bezzo

  70. Spatially Explicit Multiobjective Optimization for the Strategic Design of First and Second Generation Biorefineries Including Carbon and Water Footprints

    Article • Industrial & Engineering Chemistry Research, January 2013, American Chemical Society (ACS)

    Fabrizio Bezzo

  71. Identification of complex models of type 2 diabetes from IVGTT data by model-based design of experiments

    Article • January 2013, Elsevier

    Fabrizio Bezzo

  72. Model-based Experiment Design, Nonsequential

    Article • January 2013, Springer Science + Business Media

    Fabrizio Bezzo

  73. A spatially-explicit approach to the design of ethanol supply chains considering multiple technologies and carbon trading effects

    Article • January 2013, Elsevier

    Fabrizio Bezzo

  74. Supporting the transfer of products between different equipment through latent variable model inversion

    Article • January 2013, Elsevier

    Fabrizio Bezzo

  75. Optimizing the economics and the carbon and water footprints of bioethanol supply chains

    Article • Biofuels Bioproducts and Biorefining, September 2012, Wiley

    Fabrizio Bezzo

  76. Combining fundamental knowledge and latent variable techniques to transfer process monitoring models between plants

    Article • Chemometrics and Intelligent Laboratory Systems, July 2012, Elsevier

    Fabrizio Bezzo

  77. Environmentally conscious capacity planning and technology selection for bioethanol supply chains

    Article • Renewable Energy, July 2012, Elsevier

    Fabrizio Bezzo

  78. Online model-based redesign of experiments with erratic models: A disturbance estimation approach

    Article • Computers & Chemical Engineering, July 2012, Elsevier

    Fabrizio Bezzo

  79. Transfer of Process Monitoring Models between Different Plants Using Latent Variable Techniques

    Article • Industrial & Engineering Chemistry Research, May 2012, American Chemical Society (ACS)

    Fabrizio Bezzo

  80. A comprehensive approach to the design of ethanol supply chains including carbon trading effects

    Article • Bioresource Technology, March 2012, Elsevier

    Fabrizio Bezzo

  81. A framework for water footprint optimisation in the bioethanol supply chain

    Article • January 2012, Elsevier

    Fabrizio Bezzo

  82. A general framework for latent variable model inversion to support product and process design

    Article • January 2012, Elsevier

    Fabrizio Bezzo

  83. Parallel design of pharmacodynamic experiments for the identification of antimicrobial-resistant bacterial population models

    Article • January 2012, Elsevier

    Fabrizio Bezzo

  84. Spatially explicit multi-objective optimisation for design and planning of hybrid first and second generation biorefineries

    Article • Computers & Chemical Engineering, September 2011, Elsevier

    Fabrizio Bezzo

  85. Biofuels carbon footprints: Whole-systems optimisation for GHG emissions reduction

    Article • Bioresource Technology, August 2011, Elsevier

    Dr Jeremy Woods, Fabrizio Bezzo

  86. Identification of Physiological Models of Type 1 Diabetes Mellitus by Model-Based Design of Experiments

    Article • June 2011, Wiley

    Fabrizio Bezzo

  87. Optimization-Based Approaches for Bioethanol Supply Chains

    Article • Industrial & Engineering Chemistry Research, May 2011, American Chemical Society (ACS)

    Fabrizio Bezzo

  88. Strategic design and investment capacity planning of the ethanol supply chain under price uncertainty

    Article • Biomass and Bioenergy, May 2011, Elsevier

    Fabrizio Bezzo

  89. Model-Based Design of Experiments in the Presence of Continuous Measurement Systems

    Article • Industrial & Engineering Chemistry Research, February 2011, American Chemical Society (ACS)

    Fabrizio Bezzo

  90. A disturbance estimation approach for online model-based redesign of experiments in the presence of systematic errors

    Article • January 2011, Elsevier

    Fabrizio Bezzo

  91. An Improved Multivariate Image Analysis Method for Quality Control of Nanofiber Membranes

    Article • IFAC Proceedings Volumes, January 2011, Elsevier

    Fabrizio Bezzo

  92. Online redesign of clinical tests for the identification of type 1 diabetes models in the presence of continuous glucose monitoring systems

    Article • IFAC Proceedings Volumes, January 2011, Elsevier

    Fabrizio Bezzo

  93. Towards Second Generation Bioethanol

    Article • January 2011, Elsevier

    Fabrizio Bezzo

  94. Optimal design of clinical tests for the identification of physiological models of type 1 diabetes in the presence of model mismatch

    Article • Medical & Biological Engineering & Computing, November 2010, Springer Science + Business Media

    Fabrizio Bezzo

  95. Automatic characterization of nanofiber assemblies by image texture analysis

    Article • Chemometrics and Intelligent Laboratory Systems, August 2010, Elsevier

    Fabrizio Bezzo

  96. Simulated moving bed technology applied to coal gasification

    Article • Chemical Engineering Research and Design, April 2010, Elsevier

    Fabrizio Bezzo

  97. Artificial Vision System for the Automatic Measurement of Interfiber Pore Characteristics and Fiber Diameter Distribution in Nanofiber Assemblies

    Article • Industrial & Engineering Chemistry Research, March 2010, American Chemical Society (ACS)

    Fabrizio Bezzo

  98. Nearest-Neighbor Method for the Automatic Maintenance of Multivariate Statistical Soft Sensors in Batch Processing

    Article • Industrial & Engineering Chemistry Research, March 2010, American Chemical Society (ACS)

    Fabrizio Bezzo

  99. Enzyme adsorption on SO2 catalyzed steam-pretreated wheat and spruce material

    Article • Enzyme and Microbial Technology, March 2010, Elsevier

    Fabrizio Bezzo

  100. Capacity planning and financial optimization of the bioethanol supply chain under price uncertainty

    Article • January 2010, Elsevier

    Fabrizio Bezzo

  101. On the optimal design of clinical tests for the identification of type 1 diabetes models in the presence of continuous glucose monitoring systems

    Article • January 2010, the Institution of Engineering and Technology (the IET)

    Fabrizio Bezzo

  102. Spatially Explicit Static Model for the Strategic Design of Future Bioethanol Production Systems. 1. Cost Minimization

    Article • Energy & Fuels, October 2009, American Chemical Society (ACS)

    Fabrizio Bezzo

  103. Spatially Explicit Static Model for the Strategic Design of Future Bioethanol Production Systems. 2. Multi-Objective Environmental Optimization

    Article • Energy & Fuels, October 2009, American Chemical Society (ACS)

    Fabrizio Bezzo

  104. Online Model-Based Redesign of Experiments for Parameter Estimation in Dynamic Systems

    Article • Industrial & Engineering Chemistry Research, May 2009, American Chemical Society (ACS)

    Fabrizio Bezzo

  105. Monitoring roughness and edge shape on semiconductors through multiresolution and multivariate image analysis

    Article • AIChE Journal, May 2009, Wiley

    Fabrizio Bezzo

  106. A techno-economic comparison between two technologies for bioethanol production from lignocellulose

    Article • Biomass and Bioenergy, March 2009, Elsevier

    Fabrizio Bezzo

  107. Moving average PLS soft sensor for online product quality estimation in an industrial batch polymerization process

    Article • Journal of Process Control, March 2009, Elsevier

    Fabrizio Bezzo

  108. Multivariate statistical real-time monitoring of an industrial fed-batch process for the production of specialty chemicals

    Article • Chemical Engineering Research and Design, March 2009, Elsevier

    Fabrizio Bezzo

  109. Optimal Design of Clinical Tests for the Identification of Physiological Models of Type 1 Diabetes Mellitus

    Article • Industrial & Engineering Chemistry Research, February 2009, American Chemical Society (ACS)

    Fabrizio Bezzo

  110. A backoff strategy for model-based experiment design under parametric uncertainty

    Article • AIChE Journal, January 2009, Wiley

    Fabrizio Bezzo

  111. Effect of Substrate Specific Area on Lignocellulose Enzymatic Hydrolysis: An Experimental and Modeling Investigation

    Article • January 2009, Elsevier

    Fabrizio Bezzo

  112. On the Optimal Design of Clinical Tests for the Identification of Physiological Models of Type 1 Diabetes Mellitus

    Article • January 2009, Elsevier

    Fabrizio Bezzo

  113. Supply Chain Optimization for Bioethanol Production System in Northern Italy: Environmentally Conscious Strategic Design

    Article • January 2009, Elsevier

    Fabrizio Bezzo

  114. Ethanol from corn: a technical and economical assessment based on different scenarios

    Article • Chemical Engineering Research and Design, May 2008, Elsevier

    Fabrizio Bezzo

  115. Towards on-line model-based design of experiments

    Article • January 2008, Elsevier

    Fabrizio Bezzo

  116. Ethanol from lignocellulosic biomass: A comparison between conversion technologies

    Article • January 2007, Elsevier

    Fabrizio Bezzo

  117. Model-Based Design of Parallel Experiments

    Article • Industrial & Engineering Chemistry Research, January 2007, American Chemical Society (ACS)

    Fabrizio Bezzo

  118. MULTIVARIATE STATISTICAL ESTIMATION OF PRODUCT QUALITY IN THE INDUSTRIAL BATCH PRODUCTION OF A RESIN

    Article • IFAC Proceedings Volumes, January 2007, Elsevier

    Fabrizio Bezzo

  119. A FRAMEWORK FOR PLS-SIM INTEGRATION

    Article • January 2006, Elsevier

    Fabrizio Bezzo

  120. Optimal sensor location for distributed-sensor systems using multivariate regression

    Article • Computers & Chemical Engineering, January 2006, Elsevier

    Fabrizio Bezzo

  121. A framework for model-based design of parallel experiments in dynamic systems

    Article • January 2006, Elsevier

    Fabrizio Bezzo

  122. Using MPC to control middle-vessel continuous distillation columns

    Article • Journal of Process Control, December 2005, Elsevier

    Fabrizio Bezzo

  123. Geometric Observer for a Distillation Column:  Development and Experimental Testing

    Article • Industrial & Engineering Chemistry Research, November 2005, American Chemical Society (ACS)

    Dr Roberto Baratti, Fabrizio Bezzo

  124. Using structured and unstructured estimators for distillation units: a critical comparison

    Article • January 2005, Elsevier

    Fabrizio Bezzo

  125. Computational issues in hybrid multizonal/computational fluid dynamics models

    Article • AIChE Journal, January 2005, Wiley

    Fabrizio Bezzo

  126. Understanding the dynamic behaviour of middle-vessel continuous distillation columns

    Article • Chemical Engineering Science, January 2005, Elsevier

    Fabrizio Bezzo

  127. A general methodology for hybrid multizonal/CFD models

    Article • Computers & Chemical Engineering, April 2004, Elsevier

    Fabrizio Bezzo

  128. A general methodology for hybrid multizonal/CFD models

    Article • Computers & Chemical Engineering, April 2004, Elsevier

    Fabrizio Bezzo

  129. Using Process Simulators for Steady-State and Dynamic Plant Analysis

    Article • Chemical Engineering Research and Design, April 2004, Elsevier

    Fabrizio Bezzo

  130. General hybrid multizonal/CFD approach for bioreactor modeling

    Article • AIChE Journal, August 2003, Wiley

    Fabrizio Bezzo

  131. An object-oriented approach to hybrid CFD/multizonal modelling

    Article • January 2003, Elsevier

    Fabrizio Bezzo

  132. A general framework for the integration of computational fluid dynamics and process simulation

    Article • Computers & Chemical Engineering, July 2000, Elsevier

    Fabrizio Bezzo

  133. Steady-state analysis of an industrial reactive distillation column

    Article • Separation and Purification Technology, August 1999, Elsevier

    Fabrizio Bezzo