All Stories

  1. Improvement of tumor blood vessels enhances response to therapy

    Article • Oncogene, August 2024, Springer Science + Business Media

    Erik Henke

  2. A vascularized breast cancer spheroid platform for the ranked evaluation of tumor microenvironment-targeted drugs by light sheet fluorescence microscopy

    Article • Nature Communications, April 2024, Springer Science + Business Media

    Erik Henke

  3. Image-based modeling of vascular organization to evaluate anti-angiogenic therapy

    Article • Biology Direct, March 2023, Springer Science + Business Media

    Erik Henke

  4. Contribution of Adventitia-Derived Stem and Progenitor Cells to New Vessel Formation in Tumors

    Article • Cells, July 2021, MDPI AG

    Erik Henke

  5. Extracellular Matrix in the Tumor Microenvironment and Its Impact on Cancer Therapy

    Article • Frontiers in Molecular Biosciences, January 2020, Frontiers

    Erik Henke

  6. Generation of complex human organoid models including vascular networks by incorporation of mesodermal progenitor cells

    Article • Scientific Reports, October 2019, Springer Science + Business Media

    Erik Henke

  7. Inhibition of platelet GPVI induces intratumor hemorrhage and increases efficacy of chemotherapy in mice

    Article • Blood, June 2019, American Society of Hematology

    Erik Henke

  8. The Best for the Most Important: Maintaining a Pristine Proteome in Stem and Progenitor Cells

    Article • Stem Cells International, May 2019, Hindawi Publishing Corporation

    Süleyman Ergün, Erik Henke

  9. Restriction of drug transport by the tumor environment

    Article • Histochemistry and Cell Biology, October 2018, Springer Science + Business Media

    Erik Henke

  10. LOX-catalyzed collagen stabilization is a proximal cause for intrinsic resistance to chemotherapy

    Article • Oncogene, May 2018, Springer Science + Business Media

    Erik Henke

  11. VEGF-ablation therapy reduces drug delivery and therapeutic response in ECM-dense tumors

    Article • Oncogene, June 2016, Springer Science + Business Media

    Erik Henke

  12. Inhibition of Lysyl Oxidases Improves Drug Diffusion and Increases Efficacy of Cytotoxic Treatment in 3D Tumor Models

    Article • Scientific Reports, December 2015, Springer Science + Business Media

    Erik Henke

  13. Four different synthetic peptides of proteolipid protein induce a distinct antibody response in MP4-induced experimental autoimmune encephalomyelitis

    Article • Clinical Immunology, July 2015, Elsevier

    Erik Henke

  14. Phenotypic Diversity and Plasticity in Circulating Neutrophil Subpopulations in Cancer

    Article • Cell Reports, February 2015, Elsevier

    Erik Henke

  15. Induction of Antagonistic Soluble Decoy Receptor Tyrosine Kinases by Intronic PolyA Activation

    Article • Molecular Cell, September 2011, Elsevier

    Erik Henke

  16. Tumor Entrained Neutrophils Inhibit Seeding in the Premetastatic Lung

    Article • Cancer Cell, September 2011, Elsevier

    Erik Henke

  17. Selective Killing of Tumor Neovasculature Paradoxically Improves Chemotherapy Delivery to Tumors

    Article • Cancer Research, November 2010, American Association for Cancer Research (AACR)

    Erik Henke

  18. Inhibition of Neovascularization to Simultaneously Ameliorate Graft-vs-Host Disease and Decrease Tumor Growth

    Article • JNCI Journal of the National Cancer Institute, June 2010, Oxford University Press (OUP)

    Erik Henke

  19. Rapid Chemotherapy-Induced Acute Endothelial Progenitor Cell Mobilization: Implications for Antiangiogenic Drugs as Chemosensitizing Agents

    Article • Cancer Cell, September 2008, Elsevier

    Erik Henke

  20. Peptide-conjugated antisense oligonucleotides for targeted inhibition of a transcriptional regulator in vivo

    Article • Nature Biotechnology, January 2008, Springer Science + Business Media

    Erik Henke

  21. Improved tumor imaging and therapy via i.v. IgG–mediated time-sequential modulation of neonatal Fc receptor

    Article • Journal of Clinical Investigation, November 2007, American Society for Clinical Investigation

    Erik Henke

  22. Improved tumor imaging and therapy via i.v. IgG–mediated time-sequential modulation of neonatal Fc receptor

    Article • Journal of Clinical Investigation, September 2007, American Society for Clinical Investigation

    Erik Henke

  23. Selective Alpha-Particle Mediated Depletion of Tumor Vasculature with Vascular Normalization

    Article • PLoS ONE, March 2007, PLOS

    Erik Henke

  24. A versatile esterase fromBacillus subtilis: Cloning, expression, characterization, and its application in biocatalysis

    Article • Biotechnology Journal, February 2007, Wiley

    Erik Henke, Prof. Uwe T Bornscheuer

  25. Induction of Complete Regressions of Oncogene-induced Breast Tumors in Mice

    Article • Cold Spring Harbor Symposia on Quantitative Biology, January 2005, Cold Spring Harbor Laboratory Press

    Erik Henke

  26. A New Route to Protected Acyloins and Their Enzymatic Resolution with Lipases

    Article • European Journal of Organic Chemistry, March 2004, Wiley

    Prof. Uwe T Bornscheuer, Erik Henke

  27. Directed Evolution of Lipases and Esterases

    Article • January 2004, Elsevier

    Prof. Uwe T Bornscheuer, Erik Henke

  28. A Molecular Mechanism of Enantiorecognition of Tertiary Alcohols by Carboxylesterases

    Article • ChemBioChem, June 2003, Wiley

    Prof. Uwe T Bornscheuer, Erik Henke

  29. Mutations in Distant Residues Moderately Increase the Enantioselectivity of Pseudomonas fluorescens Esterase towards Methyl 3Bromo-2-methylpropanoate and Ethyl 3Phenylbutyrate

    Article • Chemistry - A European Journal, May 2003, Wiley

    Erik Henke, Prof. Uwe T Bornscheuer

  30. Fluorophoric Assay for the High-Throughput Determination of Amidase Activity

    Article • Analytical Chemistry, January 2003, American Chemical Society (ACS)

    Erik Henke, Prof. Uwe T Bornscheuer

  31. Esterases from Bacillus subtilis and B. stearothermophilus share high sequence homology but differ substantially in their properties

    Article • Applied Microbiology and Biotechnology, November 2002, Springer Science + Business Media

    Erik Henke, Prof. Uwe T Bornscheuer

  32. Activity of Lipases and Esterases towards Tertiary Alcohols: Insights into Structure���Function Relationships

    Article • Angewandte Chemie International Edition, September 2002, Wiley

    Erik Henke, Prof. Uwe T Bornscheuer

  33. Screening of Commercial Hydrolases for the Degradation of Ochratoxin A

    Article • Journal of Agricultural and Food Chemistry, November 2000, American Chemical Society (ACS)

    Erik Henke, Prof. Uwe T Bornscheuer

  34. Lipase-Catalyzed Resolution of Ibuprofen

    Article • Monatshefte für Chemie - Chemical Monthly, June 2000, Springer Science + Business Media

    Erik Henke

  35. Highly efficient double enantioselection by lipase-catalyzed transesterification of (R,S)-carboxylic acid vinyl esters with (RS)-1-phenylethanol

    Article • Tetrahedron Asymmetry, March 1999, Elsevier

    Erik Henke, Prof. Uwe T Bornscheuer

  36. The Use of Vinyl Esters Significantly Enhanced Enantioselectivities and Reaction Rates in Lipase-Catalyzed Resolutions of Arylaliphatic Carboxylic Acids

    Article • The Journal of Organic Chemistry, March 1999, American Chemical Society (ACS)

    Erik Henke, Prof. Uwe T Bornscheuer

  37. Directed Evolution of an Esterase from Pseudomonas fluorescens. Random Mutagenesis by Error-Prone PCR or a Mutator Strain and Identification of Mutants Showing Enhanced Enantioselectivity by a Resorufin-Based Fluorescence Assay

    Article • Biological Chemistry, January 1999, De Gruyter

    Prof. Uwe T Bornscheuer, Erik Henke