All Stories

  1. In Silico Human Cardiomyocyte Action Potential Modeling: Exploring Ion Channel Input Combinations
  2. Concurrent Validation of MI-CAT(V), a Clinical Metrology Instrument for Veterinarians Assessing Osteoarthritis Pain in Cats, through Testing for Firocoxib Analgesic Efficacy in a Prospective, Randomized, Controlled, and Blinded Study
  3. Face and Predictive Validity of MI-RAT (Montreal Induction of Rat Arthritis Testing), a Surgical Model of Osteoarthritis Pain in Rodents Combined with Calibrated Exercise
  4. Development of Two Innovative Performance-Based Objective Measures in Feline Osteoarthritis: Their Reliability and Responsiveness to Firocoxib Analgesic Treatment
  5. A 2022 Systematic Review and Meta-Analysis of Enriched Therapeutic Diets and Nutraceuticals in Canine and Feline Osteoarthritis
  6. Management of veterinary anaesthesia and analgesia in small animals: A survey of English-speaking practitioners in Canada
  7. Management of veterinary anaesthesia in small animals: A survey of current practice in Quebec
  8. Safety and efficacy of reduced dosage ketoprofen with or without tramadol for long-term treatment of osteoarthritis in dogs: a randomized clinical trial
  9. Sensitivity of functional targeted neuropeptide evaluation in testing pregabalin analgesic efficacy in a rat model of osteoarthritis pain
  10. Pain characterization and response to palliative care in dogs with naturally-occurring appendicular osteosarcoma: An open label clinical trial
  11. CANINE HEALTH-RELATED QUALITY OF LIFE INDEX (CHQoLI) v1
  12. Guide pratique menant à la caractérisation de la douleur chez l'animal de compagnie v1
  13. INDICE DE QUALITÉ DE VIE ASSOCIÉE À L’ÉTAT DE SANTÉ DU CHIEN (IQVESC) v1
  14. Practical guide to characterize the source of pain in pet animals v1
  15. Development and preliminary validity and reliability of the montreal instrument for cat arthritis testing, for use by caretaker/owner, MI-CAT(C), via a randomised clinical trial
  16. Spinal neuropeptide modulation, functional assessment and cartilage lesions in a monosodium iodoacetate rat model of osteoarthritis
  17. Cardiac contractility: Correction strategies applied to telemetry data from a HESI-sponsored consortium
  18. Validation of a thermal threshold nociceptive model in bearded dragons ( Pogona vitticeps )
  19. Analgesic efficacy of tramadol in cats with naturally occurring osteoarthritis
  20. Pharmacokinetics of Lidocaine Hydrochloride Administered with or without Adrenaline for the Paravertebral Brachial Plexus Block in Dogs
  21. Analgesic efficacy of an oral transmucosal spray formulation of meloxicam alone or in combination with tramadol in cats with naturally occurring osteoarthritis
  22. Comparison of left ventricular contractility to RR interval relationship in freely-moving rats, dogs and monkeys
  23. Gastroinstestinal motility: Motility and motor migrating complex (MMC) evaluations in rats, dogs and non-human primates
  24. Left ventricular pressure (LVP) and contractility in freely-moving rats: The application of marginal distribution analysis
  25. Concurrent validity of different functional and neuroproteomic pain assessment methods in the rat osteoarthritis monosodium iodoacetate (MIA) model
  26. The emerging role of in vitro electrophysiological methods in CNS safety pharmacology
  27. The physiology and pathophysiology of pain
  28. Rat cardiovascular telemetry: Marginal distribution applied to positive control drugs
  29. Antinociceptive effects of intravenous administration of hydromorphone hydrochloride alone or followed by buprenorphine hydrochloride or butorphanol tartrate to healthy conscious cats
  30. Preliminary Validation and Reliability Testing of the Montreal Instrument for Cat Arthritis Testing, for Use by Veterinarians, in a Colony of Laboratory Cats
  31. Left ventricular pressure (LVP) assessment screening models: Comparison of high definition telemetry in free-moving with anesthetized rats
  32. Jacketed external electroencephalographic (EEG) telemetry monitoring in conscious beagle dogs and cynomolgus monkeys: Qualification of a central nervous system safety testing model
  33. Electroencephalography (EEG) in Sprague–Dawley rats and cynomolgus monkeys: Super-intervals to increase model sensitivity
  34. [18F]-fluorodeoxyglucose positron emission tomography of the cat brain: A feasibility study to investigate osteoarthritis-associated pain
  35. Oxytocin improves the expression of cardiac specific markers in porcine bone marrow stem cells differentiation
  36. Preliminary investigation of the thermal antinociceptive effects of codeine in cats
  37. A medicinal herb-based natural health product improves the condition of a canine natural osteoarthritis model: A randomized placebo-controlled trial
  38. Telemetry video-electroencephalography (EEG) in rats, dogs and non-human primates: Methods in follow-up safety pharmacology seizure liability assessments
  39. Reprint of “Non-invasive measure of respiratory mechanics and conventional respiratory parameters in conscious large animals by high frequency Airwave Oscillometry”
  40. Reprint of “Effects of amphetamine, diazepam and caffeine on polysomnography (EEG, EMG, EOG)-derived variables measured using telemetry in Cynomolgus monkeys”
  41. Remote subcutaneous and intravenous administration in large animals: Impact on cardiovascular safety pharmacology data and sensitivity
  42. Pharmacological validation of a cardiovascular, physical activity and core body temperature telemetric monitoring test system in rats
  43. Haemodynamic interactions of medetomidine and the peripheral alpha-2 antagonist MK-467 during step infusions in isoflurane-anaesthetised dogs
  44. Association between sensitisation and pain-related behaviours in an experimental canine model of osteoarthritis
  45. Respiratory mechanics: Comparison of Beagle dogs, Göttingen minipigs and Cynomolgus monkeys
  46. Non-invasive measure of respiratory mechanics and conventional respiratory parameters in conscious large animals by high frequency Airwave Oscillometry
  47. Effects of amphetamine, diazepam and caffeine on polysomnography (EEG, EMG, EOG)-derived variables measured using telemetry in Cynomolgus monkeys
  48. Coxofemoral joint kinematics using video fluoroscopic images of treadmill-walking cats: development of a technique to assess osteoarthritis-associated disability
  49. Evoked Temporal Summation in Cats to Highlight Central Sensitization Related to Osteoarthritis-Associated Chronic Pain: A Preliminary Study
  50. Assessing experimental visceral pain in dairy cattle: A pilot, prospective, blinded, randomized, and controlled study focusing on spinal pain proteomics
  51. Letters to the Editor
  52. Excitement in dogs recovering from alfaxalone anaesthesia: is the absent drug blamed in error?
  53. Kinetic peak vertical force measurement in cats afflicted by coxarthritis: Data management and acquisition protocols
  54. Long-term performance evaluation of intravascular biopotential leads in telemetered freely moving cynomolgus monkeys
  55. Epileptic seizures characterization and automated detection in telemetered nonhuman primates
  56. Auditory evoked potentials: A feasibility study in telemetered cynomolgus monkeys
  57. Characterization of osteoarthritis in cats and meloxicam efficacy using objective chronic pain evaluation tools
  58. Does a placebo effect really occur in dogs afflicted by hip osteoarthritis as measured by force platform gait analysis?
  59. A Posteriori Comparison of Natural and Surgical Destabilization Models of Canine Osteoarthritis
  60. Validation of Orthopedic Postoperative Pain Assessment Methods for Dogs: A Prospective, Blinded, Randomized, Placebo-Controlled Study
  61. Super-intervals: Application to respiratory safety pharmacology data in rats
  62. Arousal and spectral analysis: EEG in conscious cynomolgus monkeys
  63. Beneficial effects of omega-3 fatty acids diet in canine osteoarthritis
  64. Letter to the Editor
  65. Evaluation of Osteoarthritis in Cats: Novel Information from a Pilot Study
  66. Evaluation of a fracture pain model in domestic pigeons ( Columba livia )
  67. Analgesic effects of meloxicam administration on postoperative orthopedic pain in domestic pigeons ( Columba livia )
  68. Cardiovascular Biomarkers as Examples of Success and Failure in Predicting Safety in Humans
  69. Clinical validity of outcome pain measures in naturally occurring canine osteoarthritis
  70. Brachystemma calycinum D. Don Effectively Reduces the Locomotor Disability in Dogs with Naturally Occurring Osteoarthritis: A Randomized Placebo-Controlled Trial
  71. Pain Induced by a Minor Medical Procedure (Bone Marrow Aspiration) in Dogs: Comparison of Pain Scales in a Pilot Study
  72. Evaluation of a novel ECG lead placement method in telemetered freely moving cynomolgus monkeys: Assessment of an intravascular biopotential lead
  73. Strategies to improve sensitivity of respiratory safety pharmacology studies in cynomolgus monkeys using impedance monitored by implantable telemetry
  74. Computerized arrhythmia detection in large telemetered animals: Evaluation of canine, primate, and porcine ECG data
  75. Cardiovascular and respiratory safety pharmacology in Göttingen minipigs: Pharmacological characterization
  76. An innovative surgical technique for telemetry ECG lead placement in cynomolgus monkeys (Macaca Fascicularis)
  77. Measurements of canine aqueous humor inflammatory mediators and the effect of carprofen following anterior chamber paracentesis
  78. Involvement of the nitric oxide-soluble guanylyl cyclase pathway in the oxytocin-mediated differentiation of porcine bone marrow stem cells into cardiomyocytes
  79. Tiludronate treatment improves structural changes and symptoms of osteoarthritis in the canine anterior cruciate ligament model
  80. Respiratory safety pharmacology: Concurrent validation of volume, rate, time, flow and ratio variables in conscious male Sprague–Dawley rats
  81. Treatment with Tiludronic Acid Helps Reduce the Development of Experimental Osteoarthritis Lesions in Dogs with Anterior Cruciate Ligament Transection Followed by Reconstructive Surgery: A 1-Year Study with Quantitative Magnetic Resonance Imaging
  82. 033 EFFECTS OF FEEDING A HIGH OMEGA-3 FATTY ACID DIET ON THE PAIN-RELATED DISABILITY IN DOGS WITH NATURALLY OCCURRING OSTEOARTHRITIS
  83. Arrhythmogenic liability screening in cardiovascular safety pharmacology: Commonality between non-clinical safety pharmacology and clinical thorough QT (TQT) studies
  84. Combined cardiopulmonary assessments with implantable telemetry device in conscious freely moving cynomolgus monkeys
  85. Validity of pain assessment methods in an experimental dog model
  86. Validation of pain assessment methods with clinical canine osteoarthritis
  87. Physiologic responses and pain-related behaviors in beagle dogs undergoing trochleoplasty surgery
  88. Patlak plot analysis CT-GFR for the determination of renal function: comparison of normal dogs with autologous kidney transplant dogs
  89. Influence of Changes in Body Weight on Peak Vertical Force in Osteoarthritic Dogs: A Possible Bias in Study Outcome
  90. Cardiovascular Effects of Oxytocin Infusion in a Porcine Model of Myocardial Infarct
  91. Respiratory safety pharmacology: Positive control drug responses in Sprague–Dawley rats, Beagle dogs and cynomolgus monkeys
  92. 477 VALIDATION OF CLINICAL PAIN ASSESSMENT METHODS WITH CANINE OSTEOARTHRITIS
  93. 459 JOINT MACROSCOPIC DAMAGES AND FUNCTIONAL IMPAIRMENT IN EXPERIMENTAL CANINE OSTEOARTHRITIS
  94. 141 INTERFERENCE OF CHANGES IN BODY WEIGHT ON THE WEIGHT BEARING OF DOGS WITH NATURALLY OCCURRING OSTEOARTHRITIS
  95. 138 FUNCTIONAL OUTCOMES IN DOGS WITH NATURALLY OCCURRING OSTEOARTHRITIS: FORCE PLATFORM GAIT ANALYSIS AND LOCOMOTOR ACTIVITY RECORDING
  96. 088 A STATISTICAL MODELING APPROACH OF THE RELATIONSHIPS BETWEEN SPECIFIC TISSUE LESIONS AND FUNCTIONAL DISABILITY IN EXPERIMENTAL CANINE OSTEOARTHRITIS
  97. 077 RELATIONSHIP BETWEEN CANINE STIFLE STRUCTURAL DAMAGES AND FUNCTIONAL IMPAIRMENT IN EXPERIMENTAL OSTEOARTHRITIS: PODOBAROMETRIC GAIT ANALYSIS COUPLED WITH 1.5 TESLA MAGNETIC RESONANCE IMAGING
  98. 039 VALIDITY OF PAIN ASSESSMENT METHODS IN THE EXPERIMENTAL DOG POND-NUKI MODEL
  99. 004 TILUDRONATE IN AN EXPERIMENTAL DOG MODEL OF OSTEOARTHRITIS: BONE ANTI-RESORPTIVE ACTIVITY AND RELATED FUNCTIONAL IMPROVEMENT
  100. Video-electroencephalography in conscious non human primate using radiotelemetry and computerized analysis: Refinement of a safety pharmacology model
  101. Oral treatment with a Brachystemma calycinum D don plant extract reduces disease symptoms and the development of cartilage lesions in experimental dog osteoarthritis: inhibition of protease-activated receptor 2
  102. The use of lingual venous blood to determine the acid–base and blood–gas status of dogs under anesthesia
  103. Response to the Letter to the Editor by Roemer and collaborators entitled “MRI based semi-quantitative assessment of subchondral bone marrow lesions in osteoarthritis research” concerning the article published by d'Anjou et al. entitled “Temporal asses...
  104. Metabolic stability and determination of cytochrome P450 isoenzymes' contribution to the metabolism of medetomidine in dog liver microsomes
  105. Temporal assessment of bone marrow lesions on magnetic resonance imaging in a canine model of knee osteoarthritis: impact of sequence selection
  106. Determination of glomerular filtration rate in anesthetized pigs by use of three-phase whole-kidney computed tomography and Patlak plot analysis
  107. Evidence for Non-Linear Pharmacokinetics of Oxytocin in Anesthetizetized Rat
  108. Development of a composite orthopaedic pain scale in horses
  109. Respiratory safety pharmacology: Comparison of conscious beagle dogs and cynomolgus monkey models
  110. Conscious and anesthetized non-human primate safety pharmacology models: Hemodynamic sensitivity comparison
  111. Comparison of anesthetic protocols for unconscious cardiovascular safety pharmacology
  112. Osteophytosis, Subchondral Bone Sclerosis, Joint Effusion and Soft Tissue Thickening in Canine Experimental Stifle Osteoarthritis: Comparison Between 1.5 T Magnetic Resonance Imaging and Computed Radiography
  113. Validation of respiratory safety pharmacology models: Conscious and anesthetized beagle dogs
  114. Renal effect of meloxicam versus ketoprofen in anaesthetized pseudo-normovolaemic piglets
  115. 75 QUANTITATIVE MRI ASSESSMENT OF THE PROGRESSION OF KNEE STRUCTURAL CHANGES IN AN OSTEOARTHRITIS EXPERIMENTAL DOG MODEL: CORRELATION WITH MACROSCOPIC FINDINGS
  116. Magnetic resonance imaging can accurately assess the long-term progression of knee structural changes in experimental dog osteoarthritis
  117. STUDY DESIGN IN PRECLINICAL SAFETY PHARMACOLOGY: POWER ANALYSIS OF LARGE ANIMAL MODELS
  118. STUDY DESIGN IN PRECLINICAL SAFETY PHARMACOLOGY: POWER ANALYSIS OF LARGE ANIMAL MODELS
  119. IQ/OQ/PQ OF A SYSTEM FOR RESPIRATORY SAFETY PHARMACOLOGY ASSESSMENT IN CONSCIOUS AND UNCONSCIOUS BEAGLE DOGS
  120. A cardiovascular monitoring system used in conscious cynomolgus monkeys for regulatory safety pharmacology: Part 2: Pharmacological validation
  121. A cardiovascular monitoring system in conscious cynomolgus monkeys for regulatory safety pharmacology
  122. Single-slice dynamic computed tomographic determination of glomerular filtration rate by use of Patlak plot analysis in anesthetized pigs
  123. Evaluation of epidural administration of morphine or morphine and bupivacaine for postoperative analgesia after premedication with an opioid analgesic and orthopedic surgery in dogs
  124. Increased Alveolar and Plasma Gelatinases Activity during Postpump Syndrome: Inhibition by Inhaled Nitric Oxide
  125. Use of end-tidal partial pressure of carbon dioxide to predict arterial partial pressure of carbon dioxide in harp seals during isoflurane-induced anesthesia
  126. Pre-emptive and continuous inhaled NO counteracts the cardiopulmonary consequences of extracorporeal circulation in a pig model
  127. Effects of Inhaled Nitric Oxide on Inflammation and Apoptosis After Cardiopulmonary Bypass
  128. Immunologic aspects of veterinary anesthesia and analgesia
  129. Attitudes and concerns of French veterinarians towards pain and analgesia in dogs and cats
  130. Results of preemptive epidural administration of morphine with or without bupivacaine in dogs and cats undergoing surgery: 265 cases (1997-1999)
  131. Comparison of analgesia and perioperative problems associated with the preoperative use of ketoprofen and nimesulide in dogs
  132. French veterinary attitudes toward pain evaluation and control in dogs and cats
  133. Molecular mechanisms underlying the role of nitric oxide in the cardiovascular system
  134. Phenylephrine and Inhaled Nitric Oxide
  135. Nitric oxide (NO)/nitrogen dioxide (NO2) scavengers
  136. The best approach to ARDS?
  137. Inhaled Nitric Oxide in Acute Respiratory Distress Syndrome
  138. Inhaled nitric oxide
  139. Inhaled nitric oxide: how to deliver it?
  140. Evolution of thorax X-rays in ARDS patients with or without inhaled nitric oxide
  141. Inhaled Nitric Oxide Delivery Systems
  142. Extra-pulmonary effects of inhaled nitric oxide in swine with and without phenylephrine
  143. Inhaled nitric oxide: clinical applications, indications, and toxicology
  144. should we treat acute respiratory distress syndrome with inhaled nitric oxide?
  145. Comparison of the effect of inhaled nitric oxide and intravenous nitroglycerine on hypoxia-induced pulmonary hypertension in pigs
  146. Comparison of the effect of inhaled nitric oxide and intravenous nitroglycerine on hypoxia-induced pulmonary hypertension in pigs
  147. Pharmacokinetics of epidural butorphanol in isoflurane-anaesthetized dogs
  148. Comparison of two administration techniques of inhaled nitric oxide on nitrogen dioxide production
  149. Faculty of 1000 evaluation for Spinal interleukin-1beta in a mouse model of arthritis and joint pain.
  150. Bienfaits de l’activité physique : études expérimentales