All Stories

  1. The role of menopausal symptoms on future health and longevity: A systematic scoping review of longitudinal evidence
  2. Dissecting the contribution of human chromosome 21 syntenic regions to recognition memory processes in adult and aged mouse models of Down syndrome
  3. Evaluating the Effects of Probiotics on Menopause-specific Health Outcomes: A Systematic Review & Meta-analysis
  4. Upregulation of endocytic protein expression in the Alzheimer’s disease male human brain
  5. APOE-ε4-related differences in left thalamic microstructure in cognitively healthy adults
  6. Characterisation of negative allosteric modulators of the calcium-sensing receptor, CaSR, for repurposing as a treatment for asthma
  7. Genetic risk of dementia modifies obesity effects on white matter myelin in cognitively healthy adults
  8. Correction to: ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer’s disease
  9. ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer’s disease
  10. Genetic risk of dementia modifies the impact of obesity on limbic white matter and spatial navigation behavior in cognitively healthy adults
  11. Sex-specific effects of central adiposity and inflammatory markers on limbic microstructure
  12. Selective reduction of APP-BACE1 activity improves memory via NMDA-NR2B receptor-mediated mechanisms in aged PDAPP mice
  13. Adipokines contribute to central-obesity related reductions in myelin-sensitive MRI indices in the fornix
  14. A rapidly acquired foraging-based working memory task, sensitive to hippocampal lesions, reveals age-dependent and age-independent behavioural changes in a mouse model of amyloid pathology
  15. Alterations in endocytic protein expression with increasing age in the transgenic APP695 V717I London mouse model of amyloid pathology
  16. Death Receptor 3 regulates distinct pathological attributes of acute versus chronic murine allergic lung inflammation
  17. Proteins involved in endocytosis are upregulated by ageing in the normal human brain: implications for the development of Alzheimer’s disease.
  18. Route of Administration Affects Corticosteroid Sensitivity of a Combined Ovalbumin and Lipopolysaccharide Model of Asthma Exacerbation in Guinea Pigs
  19. Effects of nebulised magnesium sulphate on inflammation and function of the guinea-pig airway
  20. Decreasing the expression of PICALM reduces endocytosis and the activity of β-secretase: implications for Alzheimer’s disease
  21. Calcium-sensing receptor antagonists abrogate airway hyperresponsiveness and inflammation in allergic asthma
  22. Pulmonary edema measured by MRI correlates with late-phase response to allergen challenge
  23. LPS exacerbates functional and inflammatory responses to ovalbumin and decreases sensitivity to inhaled fluticasone propionate in a guinea pig model of asthma
  24. Adjustment of sensitisation and challenge protocols restores functional and inflammatory responses to ovalbumin in guinea-pigs
  25. Abstracts from the 12th meeting of the International Society for Neural Transplantation and Restoration
  26. Inhibition of amyloid-β production by anti-amyloid precursor protein antibodies in primary mouse cortical neurones
  27. Human parainfluenza type 3 virus impairs the efficacy of glucocorticoids to limit allergy-induced pulmonary inflammation in guinea-pigs
  28. Functional evaluation of the receptors mediating vasoconstriction of rat aorta by trace amines and amphetamines
  29. A comparison of antiasthma drugs between acute and chronic ovalbumin-challenged guinea-pig models of asthma
  30. Bronchoprotection in conscious guinea pigs by budesonide and the NO‐donating analogue, TPI 1020, alone and combined with tiotropium or formoterol
  31. Third (2011) UK Purine Club annual symposium report
  32. Clathrin-mediated endocytic proteins are upregulated in the cortex of the Tg2576 mouse model of Alzheimer’s disease-like amyloid pathology
  33. Actions of Artemisia vulgaris extracts and isolated sesquiterpene lactones against receptors mediating contraction of guinea pig ileum and trachea
  34. Paracetamol reduces influenza-induced immunopathology in a mouse model of infection without compromising virus clearance or the generation of protective immunity
  35. Outcome-specific satiety reveals a deficit in context-outcome, but not stimulus- or action-outcome, associations in aged Tg2576 mice.
  36. Anti-amyloid precursor protein immunoglobulins inhibit amyloid-β production by steric hindrance
  37. Bradykinin-Induced Lung Inflammation and Bronchoconstriction: Role in Parainfluenze-3 Virus-Induced Inflammation and Airway Hyperreactivity
  38. Identification of trace-amine-associated receptors (TAAR) in the rat aorta and their role in vasoconstriction by β-phenylethylamine
  39. TPI 1020, a novel anti-inflammatory, nitric oxide donating compound, potentiates the bronchodilator effects of salbutamol in conscious guinea-pigs
  40. Increased muscarinic receptor activity of airway smooth muscle isolated from a mouse model of allergic asthma
  41. Atypical P2X7 receptor pharmacology in two human osteoblast-like cell lines
  42. Dietary trace amine-dependent vasoconstriction in porcine coronary artery
  43. Effects of dietary amines on the gut and its vasculature
  44. Activation of β-adrenoceptors mimics preconditioning of rat-isolated atria and ventricles against ischaemic contractile dysfunction
  45. Establishing the phenotype in novel acute and chronic murine models of allergic asthma
  46. Protective role of β2- and β3-adrenoceptors at reperfusion in isolated rat heart
  47. Radioligand binding and functional responses of ligands for human recombinant adenosine A3 receptors
  48. P2X7 Receptors Are Redistributed on Human Monocytes after Pore Formation in Response to Prolonged Agonist Exposure
  49. Distribution of P2X1 and P2X3 Receptors in the Rat and Human Urinary Bladder
  50. Apparent species differences in the kinetic properties of P2X7receptors
  51. Distribution of P2X3 receptors in the rat trigeminal ganglion after inferior alveolar nerve injury
  52. Molecular cloning and functional characterization of a rat somatostatin sst2(b)receptor splice variant
  53. Evidence for P2X3 receptors in the developing rat brain
  54. Identification and characterisation of heterogeneous somatostatin binding sites in rat distal colonic mucosa
  55. POSTER COMMUNICATIONS
  56. A quantitative autoradiographical study on the distribution of somatostatin sst2 receptors in the rat central nervous system using [125I]-BIM-23027
  57. POSTER COMMUNICATIONS
  58. Autoradiographic distribution of [3H]l-NG-Nitro-arginine binding in rat brain
  59. POSTER COMMUNICATIONS
  60. Characterisation of the non-5-HT3 high-affinity ‘R’ binding site for (R)-zacopride in brain and other tissues
  61. (?)Tertatolol is a potent antagonist at pre- and postsynaptic serotonin 5-HT1A receptors in the rat brain
  62. 5-HT3 receptors in the rat central nervous system are mainly located on nerve fibres and terminals
  63. The potent 5-HT3 receptor antagonist (R)-zacopride labels an additional high affinity site in the central nervous system
  64. Effects of repeated treatment with 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) on the autoregulatory control of dorsal raphe 5-HT neuronal firing and cortical 5-HT release
  65. Inhibition of 5-hydroxytryptamine neuronal activity by the 5-HT agonist, DOI
  66. Chronic 5-HT2 receptor antagonist treatment alters 5-HT1A autoregulatory control of 5-HT release in rat brain in vivo
  67. Autoradiographic measurement of 5-HT2 and 5-HT1C receptors an rat brain after chronic treatment with ritanserin and DOM
  68. Cortical 5-HT release in vivo after repeated treatment with a 5-HT2 agonist and a thyrotrophin releasing hormone analogue
  69. MDL 72832: a potent and stereoselective ligand at central and peripheral 5-HT1A receptors
  70. Mediation of the discriminative stimulus properties of 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT) by the putative 5-HT1A receptor