All Stories

  1. Gene therapy for haemophilia B

    Article • Haemophilia, June 2012, Wiley

    Professor Edward G D Tuddenham

  2. Human Congenital Diseases with Mixed Modes of Inheritance Have a Shortage of Recessive Disease. A Demographic Scenario?

    Article • Annals of Human Genetics, September 2011, Wiley

    Professor Edward G D Tuddenham

  3. Normal Haemostasis

    Article • October 2010, Wiley

    Professor Edward G D Tuddenham

  4. Postgraduate Haematology

    Article • October 2010, Wiley

    Professor Edward G D Tuddenham

  5. Menorrhagia in Adolescents with Inherited Bleeding Disorders

    Article • Journal of Pediatric and Adolescent Gynecology, August 2010, Elsevier

    Professor Edward G D Tuddenham

  6. Anticoagulation after liver transplantation: a retrospective audit and case–control study

    Article • Blood Coagulation & Fibrinolysis, December 2009, Wolters Kluwer Health

    Professor Edward G D Tuddenham

  7. Structural analysis of eight novel and 112 previously reported missense mutations in the interactive FXI mutation database reveals new insight on FXI deficiency

    Article • Thrombosis and Haemostasis, July 2009, Schattauer GmbH

    Professor Edward G D Tuddenham

  8. Genetic and Laboratory Diagnosis

    Article • January 2009, Wiley

    Professor Edward G D Tuddenham

  9. Identification of factor IX mutations in Iranian haemophilia B patients by SSCP and sequencing

    Article • Thrombosis Research, January 2007, Elsevier

    Professor Edward G D Tuddenham

  10. Hemophilia and Other Bleeding Disorders: Genetics

    Article • January 2006, Wiley

    Professor Edward G D Tuddenham

  11. Live birth following the first mutation specific pre-implantation genetic diagnosis for haemophilia A

    Article • Thrombosis and Haemostasis, January 2006, Schattauer GmbH

    Professor Edward G D Tuddenham

  12. Ways to bypass a blocked tenase complex

    Article • Thrombosis and Haemostasis, December 2005, Schattauer GmbH

    Professor Edward G D Tuddenham

  13. Characterisation of blood coagulation factor XIT475I

    Article • Thrombosis and Haemostasis, May 2005, Schattauer GmbH

    Professor Edward G D Tuddenham

  14. Postgraduate Haematology

    Article • March 2005, Wiley

    Professor Edward G D Tuddenham

  15. Normal Haemostasis

    Article • March 2005, Wiley

    Professor Edward G D Tuddenham

  16. Molecular Basis of Hemophilia A

    Article • January 2005, Wiley

    Professor Edward G D Tuddenham

  17. Inhibitors to Factor VIII—Molecular Basis

    Article • January 2005, Wiley

    Professor Edward G D Tuddenham

  18. Pharmacodynamic resistance to warfarin associated with a Val66Met substitution in vitamin K epoxide reductase complex subunit 1

    Article • Thrombosis and Haemostasis, December 2004, Schattauer GmbH

    Professor Edward G D Tuddenham

  19. Complete Inhibition of Acute Humoral Rejection Using Regulated Expression of Membrane-tethered Anticoagulants on Xenograft Endothelium

    Article • American Journal of Transplantation, December 2004, Elsevier

    Professor Edward G D Tuddenham

  20. Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2

    Article • February 2004

    Professor Edward G D Tuddenham

  21. Environmental and genetic factors influencing inhibitor development

    Article • Seminars in Hematology, January 2004, Elsevier

    Professor Edward G D Tuddenham

  22. Factor VIII – novel insights into form and function

    Article • British Journal of Haematology, October 2002, Wiley

    Professor Edward G D Tuddenham

  23. RNA as drug and antidote

    Article • Nature, September 2002, Springer Science + Business Media

    Professor Edward G D Tuddenham

  24. Use of a non‐depleting anti‐CD4 antibody to modulate the immune response to coagulation factors VIII and IX

    Article • British Journal of Haematology, August 2002, Wiley

    Professor Edward G D Tuddenham

  25. The Hemophilias — From Royal Genes to Gene Therapy

    Article • The New England Journal of Medicine and Surgery and the Collateral Branches of Science, June 2001, New England Journal of Medicine (NEJM/MMS)

    Professor Edward G D Tuddenham

  26. Stable recombinant expression and characterization of the two haemophilic factor VIII variants C329S (CRM−) and G1948D (CRMr)

    Article • British Journal of Haematology, June 2001, Wiley

    Professor Edward G D Tuddenham

  27. Contact activation in shock caused by invasive group A Streptococcus pyogenes

    Article • Critical Care Medicine, November 2000, Wolters Kluwer Health

    Professor Edward G D Tuddenham

  28. EXPRESSION OF NOVEL ANTICOAGULANT FUSION PROTEINS INHIBITS FACTOR XA- AND THROMBIN-INDUCED ACTIVATION OF PORCINE VASCULAR ENDOTHELIAL CELLS.

    Article • Transplantation, April 2000, Wolters Kluwer Health

    Professor Edward G D Tuddenham

  29. Factor VII deficiency and the FVII mutation database

    Article • Human Mutation, January 2000, Hindawi Publishing Corporation

    Professor Edward G D Tuddenham

  30. Postgraduate Haematology

    Article • British Journal of Haematology, August 1999, Wiley

    Professor Edward G D Tuddenham

  31. INHIBITION OF TISSUE FACTOR-DEPENDENT AND -INDEPENDENT COAGULATION BY CELL SURFACE EXPRESSION OF NOVEL ANTICOAGULANT FUSION PROTEINS

    Article • Transplantation, February 1999, Wolters Kluwer Health

    Professor Edward G D Tuddenham

  32. Factor VIII gene analysis in Japanese CRM‐positive and CRM‐reduced haemophilia A patients by single‐strand conformation polymorphism

    Article • British Journal of Haematology, September 1997, Wiley

    Professor Edward G D Tuddenham

  33. Thrombophilia: an expanding group of genetic defects that predispose to thrombosis

    Article • Molecular Medicine Today, July 1997, Elsevier

    Professor Edward G D Tuddenham

  34. Factor VIIa and the extracellular domains of human tissue factor form a compact complex: A study by X‐ray and neutron solution scattering

    Article • FEBS Letters, October 1995, Wiley

    Professor Edward G D Tuddenham

  35. Thrombogenic mechanisms investigated with coagulation activation markers after infusion of factor IX concentrates in patients with haemophilia B

    Article • Blood Coagulation & Fibrinolysis, April 1995, Wolters Kluwer Health

    Professor Edward G D Tuddenham

  36. Book Review Molecular Genetics of Haemostasis and Its Inherited Disorders (Oxford Monograph on Medical Genetics. No. 25.) By Edward G.D. Tuddenham and David N. Cooper. 585 pp. New York, Oxford University Press, 1994. $145. 0-19-261661-7

    Article • The New England Journal of Medicine and Surgery and the Collateral Branches of Science, February 1995, New England Journal of Medicine (NEJM/MMS)

    Professor Edward G D Tuddenham

  37. Molecular etiology of factor VIII deficiency in hemophilia A

    Article • Human Mutation, January 1995, Hindawi Publishing Corporation

    Professor Edward G D Tuddenham

  38. Efficient gene transfer into human umbilical vein endothelial cells allows functional analysis of the human tissue factor gene promoter

    Article • British Journal of Haematology, September 1994, Wiley

    Professor Edward G D Tuddenham

  39. Haemophilia A diagnosis by simultaneous analysis of two variable dinucleotide tandem repeats within the factor VIII gene

    Article • British Journal of Haematology, April 1994, Wiley

    Professor Edward G D Tuddenham

  40. Relationship between hemostatic abnormalities and neuroendocrine activity in heart failure

    Article • American Heart Journal, March 1994, Elsevier

    Professor Edward G D Tuddenham, Professor John GF Cleland

  41. Synthesis and characterization of wild-type and variant .gamma.-carboxyglutamic acid-containing domains of factor VII

    Article • Biochemistry, December 1993, American Chemical Society (ACS)

    Professor Edward G D Tuddenham

  42. Detection of missense mutations by single-strand conformational polymorphism (SSCP) analysis in five dysfunctional variants of coagulation factor VII

    Article • Human Molecular Genetics, January 1993, Oxford University Press (OUP)

    Professor Edward G D Tuddenham

  43. Inactivation of factor VIII by factor IXa

    Article • Biochemistry, March 1992, American Chemical Society (ACS)

    Professor Edward G D Tuddenham

  44. Cardiovascular disease: hyperlipidaemia and coagulation

    Article • Current Opinion in Lipidology, August 1991, Wolters Kluwer Health

    Professor Edward G D Tuddenham

  45. Application of PCR to the Detection and Analysis of Point Mutations in the Human Factor VIII Gene

    Article • January 1991, Springer Science + Business Media

    Professor Edward G D Tuddenham

  46. Homozygous protein C deficiency with delayed onset of symptoms at 7 to 10 months

    Article • Thrombosis Research, March 1989, Elsevier

    Professor Edward G D Tuddenham

  47. Production of factor VIII deficient plasma by immunodepletion using three monoclonal antibodies

    Article • British Journal of Haematology, August 1987, Wiley

    Professor Edward G D Tuddenham

  48. Identification of six functional clotting factor VIII:C epitopes by analysis of cross-reactive public idiotypes in murine monoclonal VIII:C inhibitors

    Article • Thrombosis Research, March 1987, Elsevier

    Professor Edward G D Tuddenham

  49. A monoclonal antibody based immunoradiometric assay for von willebrand factor: Survey of a large patient group

    Article • Thrombosis Research, January 1987, Elsevier

    Professor Edward G D Tuddenham

  50. A new polymorphism in the factor VIII gene for prenatal diagnosis of hemophilia A

    Article • Nucleic Acids Research, January 1986, Oxford University Press (OUP)

    Professor Edward G D Tuddenham

  51. Distribution of factor VIII mRNA and antigen in human liver and other tissues

    Article • Nature, October 1985, Springer Science + Business Media

    Professor Edward G D Tuddenham

  52. Purification of human factor VIII:C and its characterization by Western blotting using monoclonal antibodies

    Article • Biochemistry, July 1985, American Chemical Society (ACS)

    Professor Edward G D Tuddenham

  53. Detection and sequence of mutations in the factor VIII gene of haemophiliacs  

    Article • Nature, May 1985, Springer Science + Business Media

    Professor Edward G D Tuddenham

  54. Genetic mapping and diagnosis of haemophilia A achieved through a BclI polymorphism in the factor VIII gene

    Article • Nature, April 1985, Springer Science + Business Media

    Professor Edward G D Tuddenham

  55. An immunoradiometric assay for human factor VIII/von Willebrand factor (VIII:vWF) using a monoclonal antibody that defines a functional epitope

    Article • British Journal of Haematology, April 1985, Wiley

    Professor Edward G D Tuddenham

  56. Von Willebrand factor multimer patterns in von Willebrand's disease

    Article • British Journal of Haematology, November 1983, Wiley

    Professor Edward G D Tuddenham

  57. Synthesis and Release of Factor VIII by Cultured Human Endothelial Cells

    Article • British Journal of Haematology, April 1981, Wiley

    Professor Edward G D Tuddenham

  58. Immunologic studies of factor VIII coagulant activity (VIII:C) 1. Assays based on a haemophilic and an acquired antibody to VIII:C

    Article • Thrombosis Research, February 1981, Elsevier

    Professor Edward G D Tuddenham

  59. Professor Sen and Hare's Rule

    Article • Philosophy, October 1966, Cambridge University Press

    Professor Edward G D Tuddenham

  60. Professor Jowett

    Article • Ethics, October 1897, University of Chicago Press

    Professor Edward G D Tuddenham

  61. Monograph of the Echinodermata of the British tertiaries. By Professor Edward Forbes.

    Article • January 1852, Smithsonian Institution

    Professor Edward G D Tuddenham