All Stories

  1. Nitro-imidazole-based ruthenium complexes with antioxidant and anti-inflammatory activities
  2. Light-induced disruption of an acyl hydrazone link as a novel strategy for drug release and activation: isoniazid as a proof-of-concept case
  3. An anthracene-pendant ruthenium(ii) complex conjugated to a biotin anchor, an essential handle for photo-induced anti-cancer activity
  4. A spectroelectrochemical investigation of the heme‐based sensor DevS from Mycobacterium tuberculosis : a redox versus oxygen sensor
  5. A new water-soluble ruthenium(II) carbonyl complex: cis-[Ru(bpy)2(SO3)(CO)]
  6. Incorporation of Nitroprusside on Silica Nanoparticles—A Strategy for Safer Use of This NO Donor in Therapy
  7. In vitro and in vivo leishmanicidal activity of a ruthenium nitrosyl complex against Leishmania (Viannia) braziliensis
  8. Effect of Crotalus basiliscus snake venom on the redox reaction of myoglobin
  9. Oxygen triggers signal transduction in the DevS (DosS) sensor of Mycobacterium tuberculosis by modulating the quaternary structure
  10. Ascorbyl and hydroxyl radical generation mediated by a copper complex adsorbed on gold
  11. Escherichia coli DosC and DosP: a role of c-di-GMP in compartmentalized sensing by degradosomes
  12. Structural aspects and physiological implications of the hemoglobin of green iguana (Iguana iguana)
  13. Thiocarbonyl-bound metallonitrosyl complexes with visible-light induced DNA cleavage and promising vasodilation activity
  14. Is IQG-607 a Potential Metallodrug or Metallopro-Drug With a Defined Molecular Target in Mycobacterium tuberculosis?
  15. Antimicrobial activity of cis -[Ru(bpy) 2 (L)(L′)] n + complexes, where L = 4-(4-chlorobenzoyl)pyridine or 4-(benzoyl)pyridine and L′ = Cl − or CO
  16. Synthesis and mechanistic investigation of iron(II) complexes of isoniazid and derivatives as a redox-mediated activation strategy for anti-tuberculosis therapy
  17. A vanillin-based copper(ii) metal complex with a DNA-mediated apoptotic activity
  18. Target DNA stabilizes Mycobacterium tuberculosis DevR/DosR phosphorylation by the full-length oxygen sensors DevS/DosS and DosT
  19. The potent anti-cancer activity of Dioclea lasiocarpa lectin
  20. Photochemical studies of cis -[Ru(bpy) 2 (4-bzpy)(CO)](PF 6 ) 2 and cis -[Ru(bpy) 2 (4-bzpy)(Cl)](PF 6 ): Blue light-induced nucleobase binding
  21. Aryl-Substituted Ruthenium(II) Complexes: A Strategy for Enhanced Photocleavage and Efficient DNA Binding
  22. Insights into signal transduction by a hybrid FixL: Denaturation study of on and off states of a multi-domain oxygen sensor
  23. Drug discovery targeting heme-based sensors and their coupled activities
  24. A biphosphinic ruthenium complex with potent anti-bacterial and anti-cancer activity
  25. A Potential Visible-Light NO Releaser: Synthesis, Reactivity and Vasodilator Properties
  26. Haem-Based Sensors of O 2 : Lessons and Perspectives
  27. Synthesis, Inhibition of Mycobacterium tuberculosis Enoyl-acyl Carrier Protein Reductase and Antimycobacterial Activity of Novel Pentacyanoferrate(II)-isonicotinoylhydrazones
  28. The Heme-Based Oxygen Sensor Rhizobium etli FixL: Influence of Auxiliary Ligands on Heme Redox Potential and Implications on the Enzyme Activity
  29. Thiol-Activated HNO Release from a Ruthenium Antiangiogenesis Complex and HIF-1α Inhibition for Cancer Therapy
  30. Hydroxyl Radical Generation and DNA Nuclease Activity: A Mechanistic Study Based on a Surface-Immobilized Copper Thioether Clip-Phen Derivative
  31. The application of low angle light scattering to evaluate qualitatively and quantitatively the dynamics of formation of oligomers in heme protein sensors
  32. Ruthenium(II) bipyridine complexes with pendant anthracenyl and naphthyl moieties: A strategy for a ROS generator with DNA binding selectivity
  33. Relaxant effect of a metal-based drug in human corpora cavernosa and its mechanism of action
  34. The nitric oxide donor cis-[Ru(bpy)2(SO3)NO](PF6) increases gastric mucosa protection in mice – Involvement of the soluble guanylate cyclase/KATP pathway
  35. Non-nitric oxide based metallovasodilators: synthesis, reactivity and biological studies
  36. Photochemical and Electrochemical Study of the Release of Nitric Oxide from [Ru(bpy)2L(NO)](PF6)nComplexes (L = Imidazole, 1-Methylimidazole, Sulfite and Thiourea), Toward the Development of Therapeutic Photodynamic Agents
  37. KinChem: A Computational Resource for Teaching and Learning Chemical Kinetics
  38. [Fe(CN)5(isoniazid)]3−: An iron isoniazid complex with redox behavior implicated in tuberculosis therapy
  39. On the incorporation of Rhodamine B and 2′,7′-dichlorofluorescein dyes in silica: Synthesis of fluorescent nanoparticles
  40. Nitric Oxide Donors with Therapeutic Strategic in Experimental Schistossomiasis Mansoni
  41. Electrochemistry, Surface Plasmon Resonance, and Quartz Crystal Microbalance: An Associative Study on Cytochrome c Adsorption on Pyridine Tail-Group Monolayers on Gold
  42. The ruthenium NO donor, [Ru(bpy)2(NO)SO3](PF6), inhibits inflammatory pain: Involvement of TRPV1 and cGMP/PKG/ATP-sensitive potassium channel signaling pathway
  43. Signal Transduction and Phosphoryl Transfer by a FixL Hybrid Kinase with Low Oxygen Affinity: Importance of the Vicinal PAS Domain and Receiver Aspartate
  44. Synthesis of bifunctional mesoporous silica spheres as potential adsorbent for ions in solution
  45. Activity of IQG-607, a new orally active compound, in a murine model of Mycobacterium tuberculosis infection
  46. Using Supramolecular Chemistry Strategy for Mapping Electrochemical Phenomena on the Nanoscale
  47. Preparation, characterization and structure of ruthenium phosphine complexes containing non-innocent ligands
  48. Isoniazid metal complex reactivity and insights for a novel anti-tuberculosis drug design
  49. Hell's Gate globin I: An acid and thermostable bacterial hemoglobin resembling mammalian neuroglobin
  50. Asymmetric heterobimetallic mixed-valence complex trans-[(SO3)Co(cyclam)(NCS)Ru(NH3)4(NCS)](BF4): Synthesis and characterization
  51. Mechanism and biological implications of the NO release of cis-[Ru(bpy)2L(NO)]n+ complexes: A key role of physiological thiols
  52. NO donors cis-[Ru(bpy)2(L)NO]3+ and [Fe(CN)4(L)NO]− complexes immobilized on modified mesoporous silica spheres
  53. On the correlation between electronic intramolecular delocalization and Au-S bonding strength of ruthenium tetraammine SAMs
  54. An Oxygen-Sensing Diguanylate Cyclase and Phosphodiesterase Couple for c-di-GMP Control
  55. Oxygen‐Sensing Histidine‐Protein Kinases: Assays of Ligand Binding and Turnover of Response‐Regulator Substrates
  56. Soluble Guanylyl Cyclase and Its Evolutionary Relatives
  57. DosT and DevS are oxygen-switched kinases inMycobacterium tuberculosis
  58. A Memory of Oxygen Binding Explains the Dose Response of the Heme-Based Sensor FixL †
  59. Slow-Onset Inhibition of 2-trans-Enoyl-ACP (CoA) Reductase from Mycobacterium tuberculosis by an Inorganic Complex
  60. A Proximal Arginine R206 Participates in Switching of the Bradyrhizobium japonicum FixL Oxygen Sensor
  61. Development of a spectrophotometric assay for cyclase activity
  62. Oxygen Blocks the Reaction of the FixL−FixJ Complex with ATP but Does Not Influence Binding of FixJ or ATP to FixL†
  63. Electron transfer kinetics and mechanistic study of the thionicotinamide coordinated to the pentacyanoferrate(III)/(II) complexes: a model system for the in vitro activation of thioamides anti-tuberculosis drugs
  64. An inorganic iron complex that inhibits wild-type and an isoniazid-resistant mutant 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis
  65. Crystal structure, electrochemical and spectroscopic properties of the trans-K{[FeCl(NO0)(cyclam)]·[FeCl(NO+)(cyclam)]2}(PF6)6 complex
  66. Thermal isomerization of cis-[Fe(cyclam)Cl2]Cl·H2O complex in the solid state