All Stories

  1. NBCn1 Increases NH4+ Reabsorption Across Thick Ascending Limbs, the Capacity for Urinary NH4+ Excretion, and Early Recovery from Metabolic Acidosis

    Article • Journal of the American Society of Nephrology, January 2021, American Society of Nephrology

    Dr Ebbe Boedtkjer

  2. Upregulated Na+/H+-Exchange Protects Human Colon Cancer Tissue against Intracellular Acidification

    Article • BioMed Research International, January 2019, Hindawi Publishing Corporation

    Dr Ebbe Boedtkjer

  3. Acid–base regulation and sensing: Accelerators and brakes in metabolic regulation of cerebrovascular tone

    Article • Journal of Cerebral Blood Flow & Metabolism, October 2017, SAGE Publications

    Dr Ebbe Boedtkjer

  4. Carbonic anhydrase inhibitors modify intracellular pH transients and contractions of rat middle cerebral arteries during CO2/HCO3– fluctuations

    Article • Journal of Cerebral Blood Flow & Metabolism, March 2017, SAGE Publications

    Dr Ebbe Boedtkjer

  5. Prior renovascular hypertension does not predispose to atherosclerosis in mice

    Article • Atherosclerosis, June 2016, Elsevier

    Dr Ebbe Boedtkjer

  6. Crosstalk between cardiomyocyte-rich perivascular tissue and coronary arteries is reduced in the Zucker Diabetic Fatty rat model of type 2 diabetes mellitus

    Article • Acta Physiologica, April 2016, Wiley

    Dr Ebbe Boedtkjer

  7. Na+, HCO3−-cotransporter NBCn1 increases pHigradients, filopodia, and migration of smooth muscle cells and promotes arterial remodelling

    Article • Cardiovascular Research, April 2016, European Society of Cardiology

    Dr Ebbe Boedtkjer

  8. PROATHEROGENIC EFFECTS OF RENOVASCULAR HYPERTENSION ARE COMPLETELY RESOLVED AFTER REVERSAL TO NORMOTENSION IN MICE

    Article • Journal of the American College of Cardiology, April 2016, Elsevier

    Dr Ebbe Boedtkjer

  9. New roles of factors from perivascular tissue in regulation of vascular tone

    Article • Acta Physiologica, November 2015, Wiley

    Professor Ulf Simonsen, Dr Ebbe Boedtkjer

  10. Extracellular ʜ ᴄ ᴏ3̅ is sensed by mouse cerebral arteries: Regulation of tone by receptor protein tyrosine phosphatase γ

    Article • Journal of Cerebral Blood Flow & Metabolism, October 2015, SAGE Publications

    Dr Ebbe Boedtkjer

  11. Perivascular tissue inhibits rho-kinase-dependent smooth muscle Ca2+sensitivity and endothelium-dependent H2S signalling in rat coronary arteries

    Article • The Journal of Physiology, October 2015, Wiley

    Dr Ebbe Boedtkjer

  12. Disrupting Na+,HCO3–-cotransporter NBCn1 (Slc4a7) delays murine breast cancer development

    Article • Oncogene, July 2015, Nature

    Dr Ebbe Boedtkjer

  13. P069 Na+,HCO−3 cotransport mediates upregulated acid extrusion during human breast carcinogenesis

    Article • The Breast, March 2015, Elsevier

    Dr Ebbe Boedtkjer

  14. Synthesis of N-cyano-substituted sulfilimine and sulfoximine derivatives of S0859 and their biological evaluation as sodium bicarbonate co-transport inhibitors

    Article • MedChemComm, January 2015, Royal Society of Chemistry

    Dr Ebbe Boedtkjer

  15. Cation-Coupled Bicarbonate Transporters

    Article • September 2014, Wiley

    Dr Ebbe Boedtkjer

  16. Na+,HCO3 −-cotransport is functionally upregulated during human breast carcinogenesis and required for the inverted pH gradient across the plasma membrane

    Article • Pflügers Archiv - European Journal of Physiology, May 2014, Springer Science + Business Media

    Dr Ebbe Boedtkjer

  17. Regulation and roles of bicarbonate transporters in cancer

    Article • Frontiers in Physiology, April 2014, Frontiers

    Dr Ebbe Boedtkjer

  18. Acid-base compartmentalization in malignant tumors: Role of membrane transporters and the tumor microenvironment for cancer development

    Article • Frontiers in Pharmacology, January 2014, Frontiers

    Dr Ebbe Boedtkjer

  19. Molecular mechanisms and binding partners controlling expression, localization and function of the Na+, HCO3- cotransporter NBCn1 in cancer

    Article • Frontiers in Pharmacology, January 2014, Frontiers

    Dr Ebbe Boedtkjer

  20. Intracellular Acidification Alters Myogenic Responsiveness and Vasomotion of Mouse Middle Cerebral Arteries

    Article • Journal of Cerebral Blood Flow & Metabolism, November 2013, SAGE Publications

    Dr Ebbe Boedtkjer

  21. Acid–base transporters modulate cell migration, growth and proliferation: Implications for structure development and remodeling of resistance arteries?

    Article • Trends in Cardiovascular Medicine, April 2013, Elsevier

    Dr Ebbe Boedtkjer

  22. Endothelial alkalinisation inhibits gap junction communication and endothelium-derived hyperpolarisations in mouse mesenteric arteries

    Article • The Journal of Physiology, February 2013, Wiley

    Dr Ebbe Boedtkjer

  23. Disturbed acid-base transport: an emerging cause of hypertension

    Article • Frontiers in Physiology, January 2013, Frontiers

    Dr Ebbe Boedtkjer

  24. Contribution of Na+,HCO3−-cotransport to cellular pH control in human breast cancer: A role for the breast cancer susceptibility locus NBCn1 (SLC4A7)

    Article • International Journal of Cancer, September 2012, Wiley

    Dr Ebbe Boedtkjer

  25. Gram-Scale Solution-Phase Synthesis of Selective Sodium Bicarbonate Co-transport Inhibitor S0859: in vitro Efficacy Studies in Breast Cancer Cells

    Article • ChemMedChem, August 2012, Wiley

    Dr Ebbe Boedtkjer

  26. Physiology, Pharmacology and Pathophysiology of the pH Regulatory Transport Proteins NHE1 and NBCn1: Similarities, Differences, and Implications for Cancer Therapy

    Article • Current Pharmaceutical Design, April 2012, Bentham Science Publishers

    Dr Ebbe Boedtkjer

  27. NHE1 knockout reduces blood pressure and arterial media/lumen ratio with no effect on resting pHiin the vascular wall

    Article • The Journal of Physiology, March 2012, Wiley

    Dr Ebbe Boedtkjer

  28. Intracellular pH in the Resistance Vasculature: Regulation and Functional Implications

    Article • Journal of Vascular Research, January 2012, Karger Publishers

    Dr Ebbe Boedtkjer

  29. Disruption of Na + ,HCO 3 − Cotransporter NBCn1 (slc4a7) Inhibits NO-Mediated Vasorelaxation, Smooth Muscle Ca 2+ Sensitivity, and Hypertension Development in MiceClinical Perspective

    Article • Circulation, September 2011, Wolters Kluwer Health

    Dr Ebbe Boedtkjer

  30. Vasomotion has chloride-dependency in rat mesenteric small arteries

    Article • Pflügers Archiv - European Journal of Physiology, June 2008, Springer Science + Business Media

    Dr Ebbe Boedtkjer

  31. Antibody-independent localization of the electroneutral Na+-HCO3- cotransporter NBCn1 (slc4a7) in mice

    Article • AJP Cell Physiology, December 2007, American Physiological Society

    Dr Ebbe Boedtkjer

  32. NBCn1 (slc4a7) Mediates the Na+-Dependent Bicarbonate Transport Important for Regulation of Intracellular pH in Mouse Vascular Smooth Muscle Cells

    Article • Circulation Research, March 2006, Wolters Kluwer Health

    Dr Ebbe Boedtkjer