All Stories

  1. Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression

    Article • Nature Communications, February 2020, Springer Science + Business Media

    Dr Davis J McCarthy

  2. Eleven grand challenges in single-cell data science

    Article • February 2020, Springer Science + Business Media

    Dr Davis J McCarthy

  3. Vireo: Bayesian demultiplexing of pooled single-cell RNA-seq data without genotype reference

    Article • December 2019, Springer Science + Business Media

    Dr Davis J McCarthy

  4. 12 Grand Challenges in Single-Cell Data Science

    Article • August 2019, PeerJ

    Dr Davis J McCarthy

  5. 12 Grand Challenges in Single-Cell Data Science

    Article • August 2019, PeerJ

    Dr Davis J McCarthy

  6. 12 Grand challenges in single-cell data science

    Article • August 2019, PeerJ

    Dr Davis J McCarthy

  7. Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression

    Article • May 2019, Cold Spring Harbor Laboratory Press

    Dr Davis J McCarthy

  8. Vireo: Bayesian demultiplexing of pooled single-cell RNA-seq data without genotype reference

    Article • April 2019, Cold Spring Harbor Laboratory Press

    Dr Davis J McCarthy

  9. Combined single-cell profiling of expression and DNA methylation reveals splicing regulation and heterogeneity

    Article • February 2019, Springer Science + Business Media

    Dr Davis J McCarthy

  10. Cardelino: Integrating whole exomes and single-cell transcriptomes to reveal phenotypic impact of somatic variants

    Article • September 2018, Cold Spring Harbor Laboratory Press

    Dr Davis J McCarthy

  11. Visualization of Biomedical Data

    Article • Annual Review of Biomedical Data Science, July 2018, Annual Reviews

    Dr Davis J McCarthy

  12. Combined single cell profiling of expression and DNA methylation reveals splicing regulation and heterogeneity

    Article • May 2018, Cold Spring Harbor Laboratory Press

    Dr Davis J McCarthy

  13. Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

    Article • Scientific Data, December 2017, Nature

    Dr Davis J McCarthy, Annemari Käräjämäki

  14. f-scLVM: scalable and versatile factor analysis for single-cell RNA-seq

    Article • November 2017, Springer Science + Business Media

    Dr Davis J McCarthy

  15. NOX1 loss-of-function genetic variants in patients with inflammatory bowel disease

    Article • Mucosal Immunology, November 2017, Nature

    Dr Davis J McCarthy

  16. Erratum: Corrigendum: Common genetic variation drives molecular heterogeneity in human iPSCs

    Article • Nature, June 2017, Springer Science + Business Media

    Professor Fiona M Watt, Dr Davis J McCarthy, Dr Davide Danovi

  17. Common genetic variation drives molecular heterogeneity in human iPSCs

    Article • Nature, May 2017, Nature

    Dr Angela Goncalves, Dr Davis J McCarthy, Professor Fiona M Watt, Dr Davide Danovi

  18. Scater: pre-processing, quality control, normalization and visualization of single-cell RNA-seq data in R

    Article • Bioinformatics, January 2017, Oxford University Press (OUP)

    Dr Davis J McCarthy

  19. A step-by-step workflow for low-level analysis of single-cell RNA-seq data with Bioconductor

    Article • F1000Research, October 2016, Faculty of 1000, Ltd.

    Dr Davis J McCarthy

  20. A step-by-step workflow for low-level analysis of single-cell RNA-seq data

    Article • F1000Research, August 2016, Faculty of 1000, Ltd.

    Dr Davis J McCarthy

  21. The genetic architecture of type 2 diabetes

    Article • Nature, July 2016, Nature

    Dr Davis J McCarthy, Annemari Käräjämäki

  22. Classification of low quality cells from single-cell RNA-seq data

    Article • February 2016, Springer Science + Business Media

    Dr Davis J McCarthy

  23. Application of whole genome and RNA sequencing to investigate the genomic landscape of common variable immunodeficiency disorders

    Article • Clinical Immunology, October 2015, Elsevier

    Dr Davis J McCarthy

  24. Gain-of-Function Mutations in ZIC1 Are Associated with Coronal Craniosynostosis and Learning Disability

    Article • The American Journal of Human Genetics, September 2015, Elsevier

    Dr Davis J McCarthy

  25. Factors influencing success of clinical genome sequencing across a broad spectrum of disorders

    Article • Nature Genetics, May 2015, Nature

    Dr Davis J McCarthy

  26. MOZ and BMI1 play opposing roles during Hox gene activation in ES cells and in body segment identity specification in vivo

    Article • Proceedings of the National Academy of Sciences, April 2015, Proceedings of the National Academy of Sciences

    Dr Davis J McCarthy

  27. Erythrocytosis associated with a novel missense mutation in the BPGM gene

    Article • Haematologica, July 2014, Ferrata Storti Foundation (Haematologica)

    Dr Davis J McCarthy

  28. Whole-genome sequencing of bladder cancers reveals somatic CDKN1A mutations and clinicopathological associations with mutation burden

    Article • Nature Communications, April 2014, Nature

    Dr Davis J McCarthy

  29. Choice of transcripts and software has a large effect on variant annotation

    Article • Genome Medicine, January 2014, Springer Science + Business Media

    Dr Davis J McCarthy

  30. Count-based differential expression analysis of RNA sequencing data using R and Bioconductor

    Article • Nature Protocols, August 2013, Nature

    Dr Davis J McCarthy

  31. Homozygous mutations in a predicted endonuclease are a novel cause of congenital dyserythropoietic anemia type I

    Article • Haematologica, May 2013, Ferrata Storti Foundation (Haematologica)

    Dr Davis J McCarthy

  32. Mutations in TCF12, encoding a basic helix-loop-helix partner of TWIST1, are a frequent cause of coronal craniosynostosis

    Article • Nature Genetics, January 2013, Nature

    Dr Davis J McCarthy

  33. Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation

    Article • Nucleic Acids Research, January 2012, Oxford University Press (OUP)

    Dr Davis J McCarthy

  34. Detecting Differential Expression in RNA-sequence Data Using Quasi-likelihood with Shrunken Dispersion Estimates

    Article • Statistical Applications in Genetics and Molecular Biology, January 2012, De Gruyter

    Dr Davis J McCarthy

  35. Differential Expression for RNA Sequencing (RNA-Seq) Data: Mapping, Summarization, Statistical Analysis, and Experimental Design

    Article • September 2011, Springer Science + Business Media

    Dr Davis J McCarthy

  36. Aliskiren increases bradykinin and tissue kallikrein mRNA levels in the heart

    Article • Clinical and Experimental Pharmacology and Physiology, August 2011, Wiley

    Dr Davis J McCarthy

  37. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

    Article • Bioinformatics, November 2009, Oxford University Press (OUP)

    Dr Davis J McCarthy

  38. Testing significance relative to a fold-change threshold is a TREAT

    Article • Bioinformatics, January 2009, Oxford University Press (OUP)

    Dr Davis J McCarthy