All Stories

  1. 3-Hydroxyanthralinic acid Metabolism Controls the Hepatic Srebp/Lipoprotein axis, Inhibits Inflammasome Activation in Macrophages, and Decreases Atherosclerosis in LDLR-/- Mice

    Article • Cardiovascular Research, October 2019, Oxford University Press (OUP)

    Dr Daniel FJ Ketelhuth

  2. The immunometabolic role of indoleamine 2 3-dioxygenase in atherosclerotic cardiovascular disease: immune homeostatic mechanisms in the artery wall

    Article • Cardiovascular Research, March 2019, Oxford University Press (OUP)

    Dr Daniel FJ Ketelhuth

  3. Apoptosis and Mobilization of Lymphocytes to Cardiac Tissue Is Associated with Myocardial Infarction in a Reperfused Porcine Model and Infarct Size in Post-PCI Patients

    Article • Oxidative Medicine and Cellular Longevity, January 2018, Hindawi Publishing Corporation

    Dr Daniel FJ Ketelhuth, Dr Julio Núñez

  4. The inflammatory cytokine interferon-gamma inhibits sortilin-1 expression in hepatocytes via the JAK/STAT pathway

    Article • European Journal of Immunology, August 2017, Wiley

    Dr Daniel FJ Ketelhuth

  5. Vaccination against T-cell epitopes of native ApoB100 reduces vascular inflammation and disease in a humanized mouse model of atherosclerosis

    Article • Journal of Internal Medicine, February 2017, Wiley

    Dr Daniel FJ Ketelhuth

  6. Toll-Like Receptor 3 Influences Glucose Homeostasis and β-Cell Insulin Secretion

    Article • Diabetes, April 2015, American Diabetes Association

    Dr Daniel FJ Ketelhuth

  7. Sterile inflammation in the spleen during atherosclerosis provides oxidation-specific epitopes that induce a protective B-cell response

    Article • Proceedings of the National Academy of Sciences, April 2015, Proceedings of the National Academy of Sciences

    Dr Daniel FJ Ketelhuth

  8. Inhibition of indoleamine 2,3-dioxygenase promotes vascular inflammation and increases atherosclerosis in Apoe−/− mice

    Article • Cardiovascular Research, March 2015, European Society of Cardiology

    Dr Daniel FJ Ketelhuth

  9. The role of the kynurenine pathway of tryptophan metabolism in cardiovascular disease

    Article • Hämostaseologie, January 2015, Schattauer GmbH

    Dr Daniel FJ Ketelhuth

  10. Modulation of Autoimmunity and Atherosclerosis – Common Targets and Promising Translational Approaches Against Disease –

    Article • Circulation Journal, January 2015, Japanese Circulation Society

    Dr Daniel FJ Ketelhuth

  11. Apolipoprotein B100 danger-associated signal 1 (ApoBDS-1) triggers platelet activation and boosts platelet-leukocyte proinflammatory responses

    Article • Thrombosis and Haemostasis, May 2014, Schattauer GmbH

    Dr Daniel FJ Ketelhuth

  12. Lymphocytes in Atherosclerosis

    Article • January 2014, Springer Science + Business Media

    Dr Daniel FJ Ketelhuth

  13. Uptake of oxLDL and IL-10 Production by Macrophages Requires PAFR and CD36 Recruitment into the Same Lipid Rafts

    Article • PLoS ONE, October 2013, PLOS

    Dr Daniel FJ Ketelhuth

  14. Mycobacterium bovisBCG killed by extended freeze-drying induces an immunoregulatory profile and protects against atherosclerosis

    Article • Journal of Internal Medicine, September 2013, Wiley

    Dr Daniel FJ Ketelhuth

  15. T Cell-based Therapies for Atherosclerosis

    Article • Current Pharmaceutical Design, August 2013, Bentham Science Publishers

    Dr Daniel FJ Ketelhuth

  16. Transforming Growth Factor-  Signaling in T Cells Promotes Stabilization of Atherosclerotic Plaques Through an Interleukin-17-Dependent Pathway

    Article • Science Translational Medicine, July 2013, American Association for the Advancement of Science

    Dr Daniel FJ Ketelhuth

  17. Lack of Invariant Natural Killer T Cells Affects Lipid Metabolism in Adipose Tissue of Diet-Induced Obese Mice

    Article • Arteriosclerosis Thrombosis and Vascular Biology, March 2013, Wolters Kluwer Health

    Dr Daniel FJ Ketelhuth

  18. Depletion of FOXP3+ regulatory T cells promotes hypercholesterolemia and atherosclerosis

    Article • Journal of Clinical Investigation, February 2013, American Society for Clinical Investigation

    Professor Tim D Sparwasser, Dr Daniel FJ Ketelhuth

  19. Toll-like receptor 3 and 4 signalling through the TRIF and TRAM adaptors in haematopoietic cells promotes atherosclerosis

    Article • Cardiovascular Research, February 2013, European Society of Cardiology

    Dr Maria E Johansson, Dr Daniel FJ Ketelhuth

  20. The tryptophan metabolite 3-hydroxyanthranilic acid lowers plasma lipids and decreases atherosclerosis in hypercholesterolaemic mice

    Article • European Heart Journal, June 2012, European Society of Cardiology

    Dr Daniel FJ Ketelhuth

  21. Subcutaneous immunization with heat shock protein-65 reduces atherosclerosis in Apoe−/− mice

    Article • Immunobiology, May 2012, Elsevier

    Dr Daniel FJ Ketelhuth

  22. Identification of a Danger-Associated Peptide From Apolipoprotein B100 (ApoBDS-1) That Triggers Innate Proatherogenic Responses

    Article • Circulation, November 2011, Wolters Kluwer Health

    Dr Maria E Johansson, Dr Daniel FJ Ketelhuth

  23. Cellular immunity, low-density lipoprotein and atherosclerosis: Break of tolerance in the artery wall

    Article • Thrombosis and Haemostasis, October 2011, Schattauer GmbH

    Dr Daniel FJ Ketelhuth

  24. Immunotherapy With Tolerogenic Apolipoprotein B-100-Loaded Dendritic Cells Attenuates Atherosclerosis in Hypercholesterolemic Mice

    Article • Circulation, February 2011, Wolters Kluwer Health

    Dr Daniel FJ Ketelhuth

  25. The Role of Matrix Metalloproteinases in Atherothrombosis

    Article • Current Atherosclerosis Reports, January 2011, Springer Science + Business Media

    Dr Daniel FJ Ketelhuth

  26. Inhibition of T cell response to native low-density lipoprotein reduces atherosclerosis

    Article • The Journal of Experimental Medicine, May 2010, Rockefeller University Press

    Dr Daniel FJ Ketelhuth

  27. Intranasal Immunization With an Apolipoprotein B-100 Fusion Protein Induces Antigen-Specific Regulatory T Cells and Reduces Atherosclerosis

    Article • Arteriosclerosis Thrombosis and Vascular Biology, February 2010, Wolters Kluwer Health

    Dr Daniel FJ Ketelhuth

  28. High-Density Lipoprotein Inhibits the Uptake of Modified Low- Density Lipoprotein and the Expression of CD36 and FcγRI

    Article • Journal of Atherosclerosis and Thrombosis, January 2010, Japan Atherosclerosis Society

    Dr Daniel FJ Ketelhuth

  29. Autoantibody Response to Chromatographic Fractions from Oxidized LDL in Unstable Angina Patients and Healthy Controls

    Article • Scandinavian Journal of Immunology, October 2008, Wiley

    Dr Daniel FJ Ketelhuth

  30. Role of PPAR-gamma in the Modulation of CD36 and FcgammaRII induced by LDL with Low and High Degrees of Oxidation During the Differentiation of the Monocytic THP-1 Cell Line

    Article • Cellular Physiology and Biochemistry, January 2008, Cell Physiol Biochem Press GmbH and Co KG

    Dr Daniel FJ Ketelhuth

  31. Soy protein containing isoflavones favorably influences macrophage lipoprotein metabolism but not the development of atherosclerosis in CETP transgenic mice

    Article • Lipids, July 2006, Wiley

    Dr Daniel FJ Ketelhuth

  32. The Autoantibody Repertoire Against Copper- or Macrophage-Modified LDL Differs in Normolipidemics and Hypercholesterolemic Patients

    Article • Journal of Clinical Immunology, March 2004, Springer Science + Business Media

    Dr Daniel FJ Ketelhuth

  33. Isolation, characterization and biological activity of acidic phospholipase A2 isoforms from Bothrops jararacussu snake venom

    Article • Biochimie, October 2003, Elsevier

    Dr Daniel FJ Ketelhuth

  34. Macrophages take up triacylglycerol-rich emulsions at a faster rate upon co-incubation with native and modified LDL: An investigation on the role of natural chylomicrons in atherosclerosis

    Article • Journal of Cellular Biochemistry, November 2001, Wiley

    Dr Daniel FJ Ketelhuth