All Stories

  1. OBSCN Mutations Associated with Dilated Cardiomyopathy and Haploinsufficiency
  2. Molecular effects of the myosin activator omecamtiv mecarbil on contractile properties of skinned myocardium lacking cardiac myosin binding protein-C
  3. Synergistic role of ADP and Ca2+in diastolic myocardial stiffness
  4. Dynamics of Cell Generation and Turnover in the Human Heart
  5. Cardiac gene expression data and in silico analysis provide novel insights into human and mouse taste receptor gene regulation
  6. A novel phosphorylation site, Serine 199, in the C-terminus of cardiac troponin I regulates calcium sensitivity and susceptibility to calpain-induced proteolysis
  7. Neuregulin stimulation of cardiomyocyte regeneration in mice and human myocardium reveals a therapeutic window
  8. Spontaneous oscillatory contraction (SPOC) in cardiomyocytes
  9. Special Issue on human heart failure
  10. Implications of ADP-Stimulated Cross-Bridge Cycling for Diastolic and Systolic Heart Failure
  11. Obscurin Mutations Cause Haploinsufficiency and are Common in Patients with Familial Dilated Cardiomyopathy (FDCM)
  12. Skeletal Myosin Binding Protein-C Isoforms Modulate Actomyosin Contractility and are Regulated by Phosphorylation
  13. Oxidative Stress in Dilated Cardiomyopathy Caused byMYBPC3Mutation
  14. The role of super-relaxed myosin in skeletal and cardiac muscle
  15. Adaptations of cytoarchitecture in human dilated cardiomyopathy
  16. Cardiac stem cells: translation to human studies
  17. Nuclear pore rearrangements and nuclear trafficking in cardiomyocytes from rat and human failing hearts
  18. Differences in the regulation of RyR2 from human, sheep, and rat by Ca 2+ and Mg 2+ in the cytoplasm and in the lumen of the sarcoplasmic reticulum
  19. The Formin FHOD1 in Cardiomyocytes
  20. Phosphorylation of protein kinase C sites Ser42/44 decreases Ca2+-sensitivity and blunts enhanced length-dependent activation in response to protein kinase A in human cardiomyocytes
  21. Contractile Dysfunction of Left Ventricular Cardiomyocytes in Patients With Pulmonary Arterial Hypertension
  22. Genome-Wide Identification of Expression Quantitative Trait Loci (eQTLs) in Human Heart
  23. Gene-specific increase in the energetic cost of contraction in hypertrophic cardiomyopathy caused by thick filament mutations
  24. IN VITRO AND IN VIVO ASSESSMENTS OF CARDIAC PERFORMANCE REVEAL A GENE-SPECIFIC INCREASE IN ENERGETIC COST OF CONTRACTION IN HYPERTROPHIC CARDIOMYOPATHY DUE TO THICK FILAMENT MUTATIONS
  25. Quantification of Thyroxine and 3,5,3′-Triiodo-Thyronine in Human and Animal Hearts by a Novel Liquid Chromatography-Tandem Mass Spectrometry Method
  26. Length-dependent activation is modulated by cardiac troponin I bisphosphorylation at Ser23 and Ser24 but not by Thr143 phosphorylation
  27. Cluster of differentiation antibody microarrays on plasma immersion ion implanted polycarbonate
  28. Coxsackie and Adenovirus Receptor Is a Modifier of Cardiac Conduction and Arrhythmia Vulnerability in the Setting of Myocardial Ischemia
  29. Inhibition of RyR2 from Failing and Non-Failing Human Hearts by Calmodulin
  30. Depressed Contractility at Low-Load Spontaneous Oscillatory Contractions in Human Hypertrophic Cardiomyopathy with MYBPC3 Mutations
  31. MicroRNA transcriptome profiling in cardiac tissue of hypertrophic cardiomyopathy patients with MYBPC3 mutations
  32. Preserved cross-bridge kinetics in human hypertrophic cardiomyopathy patients with MYBPC3 mutations
  33. PKCα-Specific Phosphorylation of the Troponin Complex in Human Myocardium: A Functional and Proteomics Analysis
  34. Heart Research Advances Using Database Search Engines, Human Protein Atlas and the Sydney Heart Bank
  35. Right Ventricular Diastolic Impairment in Patients With Pulmonary Arterial Hypertension
  36. Expression Quantitative Trait Locus (eQTL) analysis in human heart for elucidation of causal genes at loci identified in genome-wide association studies
  37. Increased energy utilization for force generation in human familial hypertrophic cardiomyopathy caused by sarcomere gene mutations
  38. Differential changes in titin domain phosphorylation increase myofilament stiffness in failing human hearts
  39. Genome-wide association study of multiple congenital heart disease phenotypes identifies a susceptibility locus for atrial septal defect at chromosome 4p16
  40. Mutations in MYH7 reduce the force generating capacity of sarcomeres in human familial hypertrophic cardiomyopathy
  41. Foreword to the biophysics of protein-protein and protein-ligand interactions in dilute and crowded media—a special issue in honor of Allen Minton’s 70th birthday
  42. Familial dilated cardiomyopathy mutations uncouple troponin I phosphorylation from changes in myofibrillar Ca2+ sensitivity
  43. Perturbed Length-Dependent Activation in Human Hypertrophic Cardiomyopathy With Missense Sarcomeric Gene Mutations
  44. An Antibody-Based Leukocyte-Capture Microarray for the Diagnosis of Systemic Lupus Erythematosus
  45. Quantification of tissue T 3 and T 4 in rat and human heart by a novel HPLC-MS/MS method
  46. Cardiomyocyte proliferation contributes to heart growth in young humans
  47. Crucial Role for Ca2+/Calmodulin-Dependent Protein Kinase-II in Regulating Diastolic Stress of Normal and Failing Hearts via Titin Phosphorylation
  48. Ion implanted, radical-rich surfaces for the rapid covalent immobilization of active biomolecules
  49. Blunted Length-Dependent Activation Caused by the Homozygous TNNT2 Mutation K280N
  50. Crucial Role for Ca2+/Calmodulin-Dependent Protein Kinase-II Delta in Regulating Diastolic Stress of Normal and Failing Hearts via Titin Phosphorylation
  51. A New Functional Measure of Contractility in Human Cardiomyopathies
  52. The HCM-Associated Cardiac Troponin T Mutation K280N Increases the Energetic Cost of Tension Generation in Human Cardiac Myofibrils
  53. GSK3  Phosphorylates Newly Identified Site in the Proline-Alanine-Rich Region of Cardiac Myosin-Binding Protein C and Alters Cross-Bridge Cycling Kinetics in Human: Short Communication
  54. Metabolic Gene Remodeling and Mitochondrial Dysfunction in Failing Right Ventricular Hypertrophy Secondary to Pulmonary Arterial Hypertension
  55. Impact of site-specific phosphorylation of protein kinase A sites Ser23 and Ser24 of cardiac troponin I in human cardiomyocytes
  56. Myofibrillar Ca2+ sensitivity is uncoupled from troponin I phosphorylation in hypertrophic obstructive cardiomyopathy due to abnormal troponin T
  57. Multiple Reaction Monitoring to Identify Site-Specific Troponin I Phosphorylated Residues in the Failing Human Heart
  58. Editorial
  59. Identification and Characterization of a New Phosphorylation Site on Cardiac Myosin Binding Protein C
  60. Perturbed Length-Dependent Activation in Human HCM with Sarcomere Mutations in Thin Filament Proteins
  61. Novel Phosphorylation Sites and Reduced Phosphorylation Levels in Human Cardiac MyBP-C from Failing Hearts
  62. Reduced Length-Dependent Activation in Human Cardiomyocytes Harboring the Troponin I Mutation R145W
  63. Cardiomyocyte Hypertrophy and Reduced Myofibril Density Underlie Decreased Maximal Force Generating Capacity in Familial Hypertrophic Cardiomyopathy
  64. Spontaneous Oscillatory Contractions (SPOC): Assessing the Contractility of Human Familial Cardiomyopathies
  65. The LIM Domain Protein Family has a Surprising Influence on Heart Failure
  66. The interactome of LIM domain proteins: The contributions of LIM domain proteins to heart failure and heart development
  67. Heart of the Matter: Assessing Human Cardiomyopathies with Spontaneous Oscillatory Contractions (SPOC)
  68. Contractile Dysfunction Irrespective of the Mutant Protein in Human Hypertrophic Cardiomyopathy With Normal Systolic Function
  69. Tryptophan metabolism to kynurenine is a potential novel contributor to hypotension in human sepsis*
  70. Protein phosphatase 2A affects myofilament contractility in non-failing but not in failing human myocardium
  71. Free radical functionalization of surfaces to prevent adverse responses to biomedical devices
  72. Biophysical educational experiment: science and goodwill in Latin America and Africa
  73. A 2-D gel reference map of the basic human heart proteome
  74. Tissue Microarrays: Methods and Protocols Ronald Simon (Editor) Series: Methods in Molecular Biology, Vol. 664 Humana Press Springer Protocols 1st Edn., 2010, p. 193 ISBN: 978-1-60761-805-8
  75. Myocardial and Systemic Iron Depletion in Heart Failure
  76. A DNA-based assay for toxic chemicals in wastewater
  77. SPontaneous Oscillatory Contraction (SPOC): auto-oscillations observed in striated muscle at partial activation
  78. The HCM-Associated Cardiac Troponin T Mutation K273N Accelerates Tension Generation and Relaxation in Human Cardiac Myofibrils
  79. Reduced Maximal Force and Increased Ca2+-Sensitivity of Human Myofilaments Harbouring the HCM-Associated Cardiac Troponin T Mutation K273N
  80. Protein Kinase Cα Mediated Phosphorylation of Cardiac Troponin Reduces Maximal Force and Exerts Dual Effects on Ca2+-Sensitivity in Human Cardiomyocytes
  81. The HCM-Associated Cardiac Troponin T Mutation K273N in a Human Heart Sample Studied by in Vitro Motility Assay
  82. Spontaneous Oscillatory Contraction (SPOC): Quantifying the Contractile Performance of Human Cardiomyocytes
  83. Linker-free covalent thermophilic β-glucosidase functionalized polymeric surfaces
  84. Impact of Atrial Fibrillation on Ventricular Ion Channel and Gap Junction Expression
  85. More severe cellular phenotype in human idiopathic dilated cardiomyopathy compared to ischemic heart disease
  86. Normal passive viscoelasticity but abnormal myofibrillar force generation in human hypertrophic cardiomyopathy
  87. A Comparison of Covalent Immobilization and Physical Adsorption of a Cellulase Enzyme Mixture
  88. Protective effect of phosphorylated Hsp27 in coronary arteries through actin stabilization
  89. Erratum: Customising an antibody leukocyte capture microarray for systemic lupus erythematosus: Beyond biomarker discovery
  90. Hybrid plasma surface modification and ion implantation of biopolymers
  91. Effect of troponin I Ser23/24 phosphorylation on Ca2+-sensitivity in human myocardium depends on the phosphorylation background
  92. Heart Failure-Associated Changes in RNA Splicing of Sarcomere Genes
  93. Is There a Connection between Ablation of Atrial Fibrillation and Reduced Apoptosis?
  94. Indoleamine 2,3-Dioxygenase is Induced in Myocardium During Inflammation
  95. Myocardial and Systemic Iron Depletion in Heart Failure: Implications for Anemia Accompanying Heart Failure
  96. Impact of Atrial Fibrillation on Ventricular Calcium Handling and Contractile Function: The Role of Irregularity
  97. Proteomics of the Human Cardiac Intercalated Disc: A More Complex Multi-Functional Structure than was Previously Thought
  98. Customising an antibody leukocyte capture microarray for systemic lupus erythematosus: Beyond biomarker discovery
  99. A piece of the human heart: variance of protein phosphorylation in left ventricular samples from end-stage primary cardiomyopathy patients
  100. The use of phosphate-affinity SDS-PAGE to measure the cardiac troponin I phosphorylation site distribution in human heart muscle
  101. Protein kinase C α and ε phosphorylation of troponin and myosin binding protein C reduce Ca2+ sensitivity in human myocardium
  102. Cardiac Myosin-Binding Protein C Mutations and Hypertrophic Cardiomyopathy: Haploinsufficiency, Deranged Phosphorylation, and Cardiomyocyte Dysfunction
  103. Myosin Binding Protein C Mutations and Hypertrophic Cardiomyopathy: Haploinsufficiency, Deranged Phosphorylation and Cardiomyocyte Dysfunction
  104. SPOC: A Functional Assay of Failing and Non-Failing Human Cardiomyocytes
  105. Intercalated discs: multiple proteins perform multiple functions in non-failing and failing human hearts
  106. Atrial Fibrillation Initiates an Adverse Pattern of Molecular Remodelling in the Failing Human Heart
  107. Protein kinase G modulates human myocardial passive stiffness by phosphorylation of the titin springs
  108. Spontaneous Oscillatory Contraction: A Functional Assay of Contractile Function of Human Heart Samples Stored at −190°C
  109. CD Antibody Microarrays as an Objective Tool to Differentiate between Inflammatory Conditions of Coronary Arteries
  110. A model selection approach to discover age-dependent gene expression patterns using quantile regression models
  111. Using Antibody Arrays to Detect Microparticles from Acute Coronary Syndrome Patients Based on Cluster of Differentiation (CD) Antigen Expression
  112. Myofilament dysfunction in cardiac disease from mice to men
  113. Sex and Age Dimorphism of Myocardial Gene Expression in Nonischemic Human Heart Failure
  114. Protein Kinase G Modulates Human Myocardial Passive Stiffness by Phosphorylation of the Titin Springs
  115. INFERRING DIFFERENTIAL LEUKOCYTE ACTIVITY FROM ANTIBODY MICROARRAYS USING A LATENT VARIABLE MODEL
  116. An actin–myosin functional assay for analysis of smooth muscle (anti-microfilament) autoantibodies in human plasma
  117. The Aging Human Heart: Changes in expression of LIM Domain Proteins
  118. Intercalated Disc: Changes in Multiple Proteins Associated with Heart Failure
  119. Use of Antibody Microarrays in the Analysis of Inflammation, Autoimmunity, Viral Infection, and Cancer Metastases
  120. Actin-Binding Proteins and Disease
  121. The Role of PIP2 in Actin, Actin-Binding Proteins and Disease
  122. Actin: An Overview of Its Structure and Function
  123. Actin and Its Binding Proteins in Heart Failure
  124. Plasma immersion ion implantation treatment of polyethylene for enhanced binding of active horseradish peroxidase
  125. Stable and unstable angina: Identifying novel markers on circulating leukocytes
  126. The Regulation of Muscle Contraction: As in Life, It Keeps Getting More Complex
  127. Quantitative analysis of myofilament protein phosphorylation in small cardiac biopsies
  128. Plasma-Treated Polyethylene Surfaces for Improved Binding of Active Protein
  129. Mapping the Phosphoinositide-Binding Site on Chick Cofilin Explains How PIP2 Regulates the Cofilin-Actin Interaction
  130. Impaired Diastolic Function After Exchange of Endogenous Troponin I With C-Terminal Truncated Troponin I in Human Cardiac Muscle
  131. Proteomics and Genomics Technology: Comparison in Heart Failure and Apoptosis
  132. Nanosecond Responses of Proteins to Ultra-High Temperature Pulses
  133. Thymosin β4 Induces a Conformational Change in Actin Monomers
  134. Fluorescence Resonance Energy Transfer
  135. Cofilin, Actin and Their Complex Observed In Vivo Using Fluorescence Resonance Energy Transfer
  136. TheN-terminal fragment of gelsolin inhibits the interaction of DNase I with isolated actin, but not with the cofilin-actin complex
  137. Development of the nanotiter plate for use in antibody and cell array technologies
  138. P2X1 receptors are closely associated with connexin 43 in human ventricular myocardium
  139. A novel biosensor for mercuric ions based on motor proteins
  140. Increases in leukocyte cluster of differentiation antigen expression during cardiopulmonary bypass in patients undergoing heart transplantation (vol. 4, Issue 7, pp. 1918-1926)
  141. Editorial: AES is Reborn as AEPS
  142. Two opposite effects of cofilin on the thermal unfolding of F-actin: a differential scanning calorimetric study
  143. Increases in leukocyte cluster of differentiation antigen expression during cardiopulmonary bypass in patients undergoing heart transplantation
  144. Fluorescence Depolarization of Actin Filaments in Reconstructed Myofibers: The Effect of S1 or pPDM-S1 on Movements of Distinct Areas of Actin
  145. A novel biosensor for mercuric ions based on motor proteins
  146. Functional attachment of horse radish peroxidase to plasma-treated surfaces
  147. The 32nd European Muscle Conference
  148. Apparatus for exposing cell membranes to rapid temperature transients
  149. Comparison of gene expression between left atria and left ventricles from non-diseased humans
  150. Anatomical study of the “trochanteric bursa”
  151. Actin Binding Proteins: Regulation of Cytoskeletal Microfilaments
  152. The distribution of cofilin and DNase I in vivo
  153. Antibody arrays: an embryonic but rapidly growing technology
  154. A technique for microsecond heating and cooling of a thin (submicron) biological sample
  155. Inguinal canal ?lipoma?
  156. Cofilin and DNase I Affect the Conformation of the Small Domain of Actin
  157. Cardiac Expression and Subcellular Localization of the p38 Mitogen-activated Protein Kinase Member, Stress-activated Protein Kinase-3 (SAPK3)
  158. Molecular Interactions of Actin
  159. Controlling actin motility on microfabricated linear channels
  160. Nuclear membrane proteins in failing human dilated cardiomyopathy
  161. The affinity of chick cofilin for actin increases when actin is complexed with DNase I: Formation of a cofilin-actin-DNase I ternary complex
  162. Heart failure and apoptosis: Electrophoretic methods support data from micro- and macro-arrays. A critical review of genomics and proteomics
  163. Fluorescence Resonance Energy Transfer
  164. Molecular Interactions of Actin
  165. An Overview of Actin Structure and Actin-Binding Proteins
  166. Analysis of Models of F-Actin Using Fluorescence Resonance Energy Transfer Spectroscopy
  167. Regulation of the Cytoskeleton Assembly: a Role for a Ternary Complex of Actin with Two Actin-Binding Proteins
  168. Determination of P2X1α-sarcoglycan (adhalin) expression levels in failing human dilated cardiomyopathic left ventricles
  169. Elevated DNase activity and caspase expression in association with apoptosis in failing ischemic sheep left ventricles
  170. Changes in myocardial protein expression in pacing-induced canine heart failure
  171. Changes in myocardial protein expression in pacing-induced canine heart failure
  172. Increase in expression of P2X1 receptors in the atria of patients suffering from dilated cardiomyopathy
  173. Protein changes observed in pacing-induced heart failure using two-dimensional electrophoresis
  174. Bright sparks in Australian 2-DE: Report on the Fourth Annual Conference of the Australian Electrophoresis Society
  175. Actin-binding proteins in mouse C2 myoblasts and myotubes: A combination of affinity chromatography and two-dimensional gel electrophoresis
  176. Alterations in the expression of P2X1 receptors in failing and nondiseased human atria
  177. Interhead distances in myosin attached to F-actin estimated by fluorescence energy transfer spectroscopy
  178. Variations in the Relative mRNA Levels of Actins and Myosin Heavy Chains do not Produce Corresponding Differences in their Proteins in the Adult Human Heart
  179. The Australian Electrophoresis Society Annual Conference at Chromatography '96: Separation Sciences, Rosehill Gardens, Rosehill, NSW, Australia, July 9-11, 1996
  180. Two-dimensional gel electrophoresis of actin-binding proteins isolated by affinity chromatography from human skeletal muscle
  181. Analysis of the binding of deoxyribonuclease I to G-actin by capillary electrophoresis
  182. Structural changes in subdomain 2 of G-actin observed by fluorescence spectroscopy
  183. Distance measurements near the myosin head-rod junction using fluorescence spectroscopy
  184. Different electrophoretic techniques produce conflicting data in the analysis of myocardial samples from dilated cardiomyopathy patients: Protein levels do not necessarily reflect mRNA levels
  185. Fluorescence Resonance Energy Transfer Spectroscopy Is a Reliable "Ruler" for Measuring Structural Changes in Proteins Dispelling the Problem of the Unknown Orientation Factor
  186. Actin and the actomyosin interface: a review
  187. Determination of the Radial Coordinate of Cys-374 in F-Actin Using Fluorescence Resonance Energy Transfer Spectroscopy: Effect of Phalloidin on Polymer Assembly
  188. Evidence for an F-Actin Like Conformation in the ACTIN:DNASE I Complex
  189. Myosin Light Chain Gene Expression Associated with Disease States of the Human Heart
  190. Flavivirus induces MHC antigen on human myoblasts: A model of autoimmune myositis?
  191. Structure of actin observed by fluorescence resonance energy transfer spectroscopy
  192. Uncoupling of actin-activated myosin ATPase activity from actin binding by a monoclonal antibody directed against the N-terminus of myosin light chain 1
  193. Removing the two C-terminal residues of actin affects the filament structure
  194. Effects of sulphydryl modification on skinned rat skeletal muscle fibres using 5,5'-dithiobis(2-nitrobenzoic acid).
  195. Actin dynamics studied by solid-state NMR spectroscopy
  196. The effect of the replacement of ADP with a photoaffinity ATP analogue, 2-azido-ADP, in F-actin on its function
  197. Fluorine-19 NMR studies of the interaction of selectively labeled actin and myosin
  198. Fluorescence resonance energy transfer measurements of distances in actin and myosin. A critical evaluation
  199. Fluorescence resonance energy transfer between the nucleotide binding site and Cys-10 in G-actin and F-actin
  200. Fluorescence energy transfer between nucleotide binding sites in an F-action filament
  201. Structural and functional domains on actin
  202. Actin tube formation: effects of variations in commonly used solvent conditions
  203. Fluorescence energy transfer between probes on actin and probes on myosin
  204. Actin: Structure and Function in Muscle and Non-Muscle Cells. Proceedings of an International Seminar, Held in Conjuction with the 12th International Congress of Biochemistry, at The University Sydney, 23-25 August 1982. Cristobal G. dos Remedios Juli...
  205. A re-investigation of actin monomer conformation under polymerizing conditions based on rates of enzymatic digestion and ultraviolet difference spectroscopy
  206. Actin monomer conformation under polymerizing conditions studied by proton nuclear magnetic resonance and circular dichroism spectroscopy
  207. Differences between skeletal muscle actin from rabbit and pig
  208. Electron diffraction and computed fourier transform study of lanthanide actin microcrystals
  209. Crystalline actin tubes
  210. Lanthanide ion probes of calcium-binding sites on cellular membranes
  211. Proton nuclear magnetic resonance and electron paramagnetic resonance studies on skeletal muscle actin indicate that the metal and nucleotide binding sites are separate
  212. Crystalline actin tubes I. Is the conformation of the lanthanide-induced actin tube monomer more like F-actin than G-actin?
  213. Crystalline actin tubes II. The effect of various lanthanide ions on actin tube formation
  214. Structural similarities and differences between crystalline actin aggregates formed by the lanthanide ions
  215. Binding stoichiometry of gadolinium to actin: Its effect on the actin-bound divalent cation
  216. Actin microcrystals and tubes formed in the presence of gadolinium ions
  217. Evidence for the non-filamentous aggregation of actin induced by lanthanide ions
  218. Ionic radius selectivity of skeletal muscle membranes
  219. Responses of skeletal muscle fibres to lanthanide ions. Dependence of the twitch response on ionic radii
  220. Effects of Gd(III) on G-actin: Inhibition of polymerization of G-actin and activation of myosin ATPase activity by Gd-G-actin
  221. The dependence of rigor tension on sarcomere length in vertebrate muscle
  222. Does a Myosin Cross-Bridge Progress Arm-over-Arm on the Actin Filament?
  223. TORQUE DEVELOPED IN SINGLE AND SMALL BUNDLES OF GLYCERINATED RABBIT PSOAS MUSCLE FIBRES UNDER CHEMICALLY-INDUCED CONDITIONS OF RIGOR, RELAXATION AND CONTRACTION
  224. Proteomics in Cardiovascular Disease