All Stories

  1. Impact of transferable β-lactamases and intrinsic AmpC amino acid substitutions on the activity of cefiderocol against wild-type and iron uptake-deficient mutants of Pseudomonas aeruginosa

    Article • Journal of Antimicrobial Chemotherapy, September 2024, Oxford University Press (OUP)

    Concepcion Gonzalez-Bello

  2. Chemical sensors for the early diagnosis of bacterial resistance to β-lactam antibiotics

    Article • Bioorganic Chemistry, June 2024, Elsevier

    Concepcion Gonzalez-Bello

  3. Novel Penicillin-Based Sulfone-Siderophore Conjugates for Restoring β-Lactam Antibiotic Efficacy

    Article • ACS Omega, May 2024, American Chemical Society (ACS)

    Concepcion Gonzalez-Bello

  4. Modulation of the photobehavior of gefitinib and its phenolic metabolites by human transport proteins

    Article • Frontiers in Pharmacology, May 2024, Frontiers

    Concepcion Gonzalez-Bello

  5. In vitro development of imipenem/relebactam resistance in KPC-producing Klebsiella pneumoniae involves multiple mutations including OmpK36 disruption and KPC modification

    Article • International Journal of Antimicrobial Agents, August 2023, Elsevier

    Concepcion Gonzalez-Bello

  6. Interplay between OXA-10 β-Lactamase Production and Low Outer-Membrane Permeability in Carbapenem Resistance in Enterobacterales

    Article • Antibiotics, June 2023, MDPI AG

    Concepcion Gonzalez-Bello

  7. Antimicrobial Activity of Cefiderocol against the Carbapenemase-Producing Enterobacter cloacae Complex and Characterization of Reduced Susceptibility Associated with Metallo-β-Lactamase VIM-1

    Article • Antimicrobial Agents and Chemotherapy, May 2023, ASM Journals

    Concepcion Gonzalez-Bello

  8. Siderophores: Chemical tools for precise antibiotic delivery

    Article • Bioorganic & Medicinal Chemistry Letters, May 2023, Elsevier

    Concepcion Gonzalez-Bello

  9. Quinate-based ligands for irreversible inactivation of the bacterial virulence factor DHQ1 enzyme—A molecular insight†

    Article • Frontiers in Molecular Biosciences, January 2023, Frontiers

    Concepcion Gonzalez-Bello

  10. Singlet oxygen and radical-mediated mechanisms in the oxidative cellular damage photosensitized by the protease inhibitor simeprevir

    Article • Free Radical Biology and Medicine, January 2023, Elsevier

    Concepcion Gonzalez-Bello

  11. In Silico Simulations and Functional Cell Studies Evidence Similar Potency and Distinct Binding of Pacific and Caribbean Ciguatoxins

    Article • Exposure and Health, October 2022, Springer Science + Business Media

    Concepcion Gonzalez-Bello

  12. Regioselective Synthesis of 2-Aryl-5-cyano-1-(2-hydroxyaryl)-1H-imidazole-4-carboxamides Self-Assisted by a 2-Hydroxyaryl Group

    Article • ACS Omega, June 2022, American Chemical Society (ACS)

    Concepcion Gonzalez-Bello

  13. Discovery of 3H-pyrrolo[2,3-c]quinolines with activity against Mycobacterium tuberculosis by allosteric inhibition of the glutamate-5-kinase enzyme

    Article • European Journal of Medicinal Chemistry, March 2022, Elsevier

    Concepcion Gonzalez-Bello

  14. Selection of AmpC β-Lactamase Variants and Metallo-β-Lactamases Leading to Ceftolozane/Tazobactam and Ceftazidime/Avibactam Resistance during Treatment of MDR/XDR Pseudomonas aeruginosa Infections

    Article • Antimicrobial Agents and Chemotherapy, February 2022, ASM Journals

    Concepcion Gonzalez-Bello

  15. Switching from ultrafast electron transfer to proton transfer in excited drug–protein complexes upon biotransformation

    Article • Chemical Science, January 2022, Royal Society of Chemistry

    Concepcion Gonzalez-Bello

  16. 6-Halopyridylmethylidene Penicillin-Based Sulfones Efficiently Inactivate the Natural Resistance of Pseudomonas aeruginosa to β-Lactam Antibiotics

    Article • Journal of Medicinal Chemistry, April 2021, American Chemical Society (ACS)

    Concepcion Gonzalez-Bello

  17. Activity of Imipenem, Meropenem, Cefepime, and Sulbactam in Combination with the β-Lactamase Inhibitor LN-1-255 against Acinetobacter spp.

    Article • Antibiotics, February 2021, MDPI AG

    Concepcion Gonzalez-Bello

  18. Protein Binding of Lapatinib and Its N- and O-Dealkylated Metabolites Interrogated by Fluorescence, Ultrafast Spectroscopy and Molecular Dynamics Simulations

    Article • Frontiers in Pharmacology, October 2020, Frontiers

    Concepcion Gonzalez-Bello

  19. Characterization of Locally Excited and Charge‐Transfer States of the Anticancer Drug Lapatinib by Ultrafast Spectroscopy and Computational Studies

    Article • Chemistry - A European Journal, October 2020, Wiley

    Concepcion Gonzalez-Bello

  20. Molecular mechanisms driving thein vivodevelopment of OXA-10-mediated resistance to ceftolozane/tazobactam and ceftazidime/avibactam during treatment of XDRPseudomonas aeruginosainfections

    Article • Journal of Antimicrobial Chemotherapy, October 2020, Oxford University Press (OUP)

    Concepcion Gonzalez-Bello

  21. Molecular and biochemical insights into the in vivo evolution of AmpC-mediated resistance to ceftolozane/tazobactam during treatment of an MDR Pseudomonas aeruginosa infection

    Article • Journal of Antimicrobial Chemotherapy, July 2020, Oxford University Press (OUP)

    Concepcion Gonzalez-Bello

  22. Cover Feature: Self‐Immolation of a Bacterial Dehydratase Enzyme by its Epoxide Product (Chem. Eur. J. 36/2020)

    Article • Chemistry - A European Journal, June 2020, Wiley

    Concepcion Gonzalez-Bello

  23. Self‐Immolation of a Bacterial Dehydratase Enzyme by its Epoxide Product

    Article • Chemistry - A European Journal, June 2020, Wiley

    Concepcion Gonzalez-Bello

  24. 6-Arylmethylidene Penicillin-Based Sulfone Inhibitors for Repurposing Antibiotic Efficiency in Priority Pathogens

    Article • Journal of Medicinal Chemistry, March 2020, American Chemical Society (ACS)

    Concepcion Gonzalez-Bello

  25. Investigation of metabolite-protein interactions by transient absorption spectroscopy and in silico methods

    Article • Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, February 2020, Elsevier

    Concepcion Gonzalez-Bello

  26. β-Lactamase Inhibitors To Restore the Efficacy of Antibiotics against Superbugs

    Article • Journal of Medicinal Chemistry, October 2019, American Chemical Society (ACS)

    Concepcion Gonzalez-Bello

  27. Challenging Antimicrobial Susceptibility and Evolution of Resistance (OXA-681) during Treatment of a Long-Term Nosocomial Infection Caused by a Pseudomonas aeruginosa ST175 Clone

    Article • Antimicrobial Agents and Chemotherapy, October 2019, ASM Journals

    Concepcion Gonzalez-Bello

  28. Therapeutic Efficacy of LN-1-255 in Combination with Imipenem in Severe Infection Caused by Carbapenem-Resistant Acinetobacter baumannii

    Article • Antimicrobial Agents and Chemotherapy, October 2019, ASM Journals

    Concepcion Gonzalez-Bello

  29. Recently developed synthetic compounds with anti-infective activity

    Article • Current Opinion in Pharmacology, October 2019, Elsevier

    Concepcion Gonzalez-Bello

  30. Photobinding of Triflusal to Human Serum Albumin Investigated by Fluorescence, Proteomic Analysis, and Computational Studies

    Article • Frontiers in Pharmacology, September 2019, Frontiers

    Concepcion Gonzalez-Bello

  31. Hydroxylammonium derivatives for selective active-site lysine modification in the anti-virulence bacterial target DHQ1 enzyme

    Article • Organic Chemistry Frontiers, January 2019, Royal Society of Chemistry

    Concepcion Gonzalez-Bello

  32. Synthesis of rigidified shikimic acid derivatives by ring-closing metathesis to imprint inhibitor efficacy against shikimate kinase enzyme

    Article • Organic Chemistry Frontiers, January 2019, Royal Society of Chemistry

    Concepcion Gonzalez-Bello

  33. Identification of a common recognition center for a photoactive non-steroidal antiinflammatory drug in serum albumins of different species

    Article • Organic Chemistry Frontiers, January 2019, Royal Society of Chemistry

    Concepcion Gonzalez-Bello

  34. The Inhibition of Lipid A Biosynthesis-The Antidote Against Superbugs?

    Article • Advanced Therapeutics, November 2018, Wiley

    Concepcion Gonzalez-Bello

  35. Photogeneration of Quinone Methides as Latent Electrophiles for Lysine Targeting

    Article • The Journal of Organic Chemistry, October 2018, American Chemical Society (ACS)

    Concepcion Gonzalez-Bello

  36. A combined photophysical and computational study on the binding of mycophenolate mofetil and its major metabolite to transport proteins

    Article • Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, June 2018, Elsevier

    Concepcion Gonzalez-Bello

  37. QM/MM simulations identify the determinants of catalytic activity differences between type II dehydroquinase enzymes

    Article • Organic & Biomolecular Chemistry, January 2018, Royal Society of Chemistry

    Concepcion Gonzalez-Bello

  38. 31.5.1.2.7 Synthesis of Phenols and Phenolates by Elimination (Update 2018)

    Article • January 2018, Thieme Publishing Group

    Concepcion Gonzalez-Bello

  39. 31.5.1.1.18 Synthesis of Phenols and Phenolates by Substitution (Update 2018)

    Article • January 2018, Thieme Publishing Group

    Concepcion Gonzalez-Bello

  40. 31.5.1.3.6 Synthesis of Phenols and Phenolates by Rearrangement (Update 2018)

    Article • January 2018, Thieme Publishing Group

    Concepcion Gonzalez-Bello

  41. 31.5.1.4.3 Synthesis of Phenols and Phenolates with Retention of the Functional Group (Update 2018)

    Article • January 2018, Thieme Publishing Group

    Concepcion Gonzalez-Bello

  42. A New Pathway for Protein Haptenation by β-Lactams

    Article • Chemistry - A European Journal, September 2017, Wiley

    Concepcion Gonzalez-Bello

  43. Reducing the Flexibility of Type II Dehydroquinase for Inhibition: A Fragment-Based Approach and Molecular Dynamics Study

    Article • ChemMedChem, September 2017, Wiley

    Concepcion Gonzalez-Bello

  44. Antibiotic adjuvants – A strategy to unlock bacterial resistance to antibiotics

    Article • Bioorganic & Medicinal Chemistry Letters, September 2017, Elsevier

    Concepcion Gonzalez-Bello

  45. Activity of the β-Lactamase Inhibitor LN-1-255 against Carbapenem-Hydrolyzing Class D β-Lactamases from Acinetobacter baumannii

    Article • Antimicrobial Agents and Chemotherapy, August 2017, ASM Journals

    Concepcion Gonzalez-Bello

  46. Mapping a protein recognition centre with chiral photoactive ligands. An integrated approach combining photophysics, reactivity, proteomics and molecular dynamics simulation studies

    Article • Chemical Science, January 2017, Royal Society of Chemistry

    Concepcion Gonzalez-Bello

  47. Frontispiece: Freezing the Dynamic Gap for Selectivity: Motion-Based Design of Inhibitors of the Shikimate Kinase Enzyme

    Article • Chemistry - A European Journal, December 2016, Wiley

    Concepcion Gonzalez-Bello

  48. Freezing the Dynamic Gap for Selectivity: Motion-Based Design of Inhibitors of the Shikimate Kinase Enzyme

    Article • Chemistry - A European Journal, October 2016, Wiley

    Concepcion Gonzalez-Bello

  49. Targeting the Motion of Shikimate Kinase: Development of Competitive Inhibitors that Stabilize an Inactive Open Conformation of the Enzyme

    Article • Journal of Medicinal Chemistry, June 2016, American Chemical Society (ACS)

    Concepcion Gonzalez-Bello

  50. LN-1-255, a penicillanic acid sulfone able to inhibit the class D carbapenemase OXA-48

    Article • Journal of Antimicrobial Chemotherapy, April 2016, Oxford University Press (OUP)

    Concepcion Gonzalez-Bello

  51. ChemInform Abstract: Designing Irreversible Inhibitors - Worth the Effort?

    Article • ChemInform, February 2016, Wiley

    Concepcion Gonzalez-Bello

  52. Study of the Phosphoryl-Transfer Mechanism of Shikimate Kinase by NMR Spectroscopy

    Article • Chemistry - A European Journal, January 2016, Wiley

    Concepcion Gonzalez-Bello

  53. Degradation of the active species in the catalytic system Pd(OAc)2/NEt3

    Article • RSC Advances, January 2016, Royal Society of Chemistry

    Concepcion Gonzalez-Bello

  54. Inhibition of Shikimate Kinase and Type II Dehydroquinase for Antibiotic Discovery: Structure-Based Design and Simulation Studies

    Article • Current Topics in Medicinal Chemistry, November 2015, Bentham Science Publishers

    Concepcion Gonzalez-Bello

  55. Designing Irreversible Inhibitors-Worth the Effort?

    Article • ChemMedChem, November 2015, Wiley

    Concepcion Gonzalez-Bello

  56. Specific chemical modification of bacterial type I dehydroquinase – opportunities for drug discovery

    Article • Future Medicinal Chemistry, November 2015, Future Science

    Concepcion Gonzalez-Bello

  57. Hydrolysis of imidazolidine ligands mediated by CuII: Mononuclear, tetranuclear and 1D CuII-amine complexes

    Article • Polyhedron, November 2015, Elsevier

    Concepcion Gonzalez-Bello

  58. Chemical Modification of a Dehydratase Enzyme Involved in Bacterial Virulence by an Ammonium Derivative: Evidence of its Active Site Covalent Adduct

    Article • Journal of the American Chemical Society, July 2015, American Chemical Society (ACS)

    Concepcion Gonzalez-Bello

  59. Using Surface Enhanced Raman Scattering to Analyze the Interactions of Protein Receptors with Bacterial Quorum Sensing Modulators

    Article • ACS Nano, May 2015, American Chemical Society (ACS)

    Concepcion Gonzalez-Bello

  60. Irreversible covalent modification of type I dehydroquinase with a stable Schiff base

    Article • Organic & Biomolecular Chemistry, January 2015, Royal Society of Chemistry

    Concepcion Gonzalez-Bello

  61. Bridging the Dimensions: How 2D Structure-activity Relationships and 3D Structural Binding Affinity help to Guide Medicinal Chemistry

    Article • Medicinal Chemistry, January 2015, OMICS Publishing Group

    Concepcion Gonzalez-Bello

  62. Total Hydrolysis of a New Imidazolidine Induced by ZnII

    Article • October 2014, MDPI AG

    Concepcion Gonzalez-Bello

  63. Insights into substrate binding and catalysis in bacterial type I dehydroquinase

    Article • Biochemical Journal, September 2014, Portland Press Ltd.

    Concepcion Gonzalez-Bello

  64. Exploring the Water-Binding Pocket of the Type II Dehydroquinase Enzyme in the Structure-Based Design of Inhibitors

    Article • Journal of Medicinal Chemistry, April 2014, American Chemical Society (ACS)

    Concepcion Gonzalez-Bello

  65. Mechanistic insight into the reaction catalysed by bacterial type II dehydroquinases

    Article • Biochemical Journal, March 2014, Portland Press Ltd.

    Concepcion Gonzalez-Bello

  66. Dual role of 2-tosylaminomethylaniline as a ligand and a nucleophile in the copper-mediated oxidation of methanol

    Article • Dalton Transactions, January 2014, Royal Society of Chemistry

    Concepcion Gonzalez-Bello

  67. Irreversible covalent modification of type I dehydroquinase: Structure-based design and simulation studies

    Article • Medicinal Chemistry, January 2014, OMICS Publishing Group

    Concepcion Gonzalez-Bello

  68. Predicting ligand binding affinity: A comparative study on the use of docking vs. Bayesian categorization and random forest recursive partitioning

    Article • Medicinal Chemistry, January 2014, OMICS Publishing Group

    Concepcion Gonzalez-Bello

  69. A convenient Pd-mediated oxidation of 4-methylbenzyl alcohol

    Article • October 2013, MDPI AG

    Concepcion Gonzalez-Bello

  70. Computational studies on the palladium-mediated oxidation of methanol to formaldehyde

    Article • October 2013, MDPI AG

    Concepcion Gonzalez-Bello

  71. Copper-mediated aerobic synthesis of 3-tosyl-1,2,3,4-tetrahydroquinazoline from 2 tosylaminomethylaniline and methanol

    Article • October 2013, MDPI AG

    Concepcion Gonzalez-Bello

  72. Mechanistic insights into a Zn-assisted ring-chain tautomerism process involving a 1,2,3,4-tetrahydroquinazoline and a Schiff base

    Article • October 2013, MDPI AG

    Concepcion Gonzalez-Bello

  73. Mycobacterium tuberculosis Shikimate Kinase Inhibitors: Design and Simulation Studies of the Catalytic Turnover

    Article • Journal of the American Chemical Society, August 2013, American Chemical Society (ACS)

    Concepcion Gonzalez-Bello, Dr Antonio L Llamas-Saiz

  74. Comparative Binding Energy (COMBINE) Analysis for Understanding the Binding Determinants of Type II Dehydroquinase Inhibitors

    Article • ChemMedChem, March 2013, Wiley

    Concepcion Gonzalez-Bello

  75. Serendipitous formation of 3-tosyl-1,2,3,4-tetrahydroquinazoline

    Article • New Journal of Chemistry, January 2013, Royal Society of Chemistry

    Concepcion Gonzalez-Bello

  76. Design and investigation of multivalent ligands for the detection and treatment of diseases

    Article • Medicinal Chemistry, January 2013, OMICS Publishing Group

    Concepcion Gonzalez-Bello

  77. Structure of Helicobacter pylori Type II Dehydroquinase inhibited by (2S)-2-(4-methoxy)benzyl-3-dehydroquinic acid

    Article • December 2012, Protein Data Bank, Rutgers University

    Concepcion Gonzalez-Bello, Dr Antonio L Llamas-Saiz

  78. Structure of Helicobacter pylori Type II Dehydroquinase inhibited by (2S)-2-Perfluorobenzyl-3-dehydroquinic acid

    Article • December 2012, Protein Data Bank, Rutgers University

    Concepcion Gonzalez-Bello, Dr Antonio L Llamas-Saiz

  79. Mechanistic Basis of the Inhibition of Type II Dehydroquinase by (2S)- and (2R)-2-Benzyl-3-dehydroquinic Acids

    Article • ACS Chemical Biology, December 2012, American Chemical Society (ACS)

    Concepcion Gonzalez-Bello, Dr Antonio L Llamas-Saiz

  80. ChemInform Abstract: Six-Membered Heterocycles: Pyridines

    Article • ChemInform, January 2012, Wiley

    Concepcion Gonzalez-Bello

  81. Metal-Assisted Ring-Closing/Opening Process of a Chiral Tetrahydroquinazoline

    Article • Inorganic Chemistry, January 2012, American Chemical Society (ACS)

    Concepcion Gonzalez-Bello

  82. Structural variety of zinc and copper complexes based on a 2,3-disubstituted 1,2,3,4-tetrahydroquinazoline ligand

    Article • Dalton Transactions, January 2012, Royal Society of Chemistry

    Concepcion Gonzalez-Bello

  83. Synthesis of 3-alkyl enol mimics inhibitors of type II dehydroquinase: factors influencing their inhibition potency

    Article • Organic & Biomolecular Chemistry, January 2012, Royal Society of Chemistry

    Concepcion Gonzalez-Bello

  84. Benzenediazonium-2-carboxylate

    Article • September 2011, Wiley

    Concepcion Gonzalez-Bello

  85. A Prodrug Approach for Improving Antituberculosis Activity of Potent Mycobacterium tuberculosis Type II Dehydroquinase Inhibitors

    Article • Journal of Medicinal Chemistry, August 2011, American Chemical Society (ACS)

    Concepcion Gonzalez-Bello, Dr Antonio L Llamas-Saiz

  86. Six-Membered Heterocycles: Pyridines

    Article • July 2011, Wiley

    Concepcion Gonzalez-Bello

  87. C. González-Bello

    Article • ChemMedChem, January 2011, Wiley

    Concepcion Gonzalez-Bello

  88. Tetrahydrobenzothiophene Derivatives: Conformationally Restricted Inhibitors of Type II Dehydroquinase

    Article • ChemMedChem, November 2010, Wiley

    Concepcion Gonzalez-Bello, Dr Antonio L Llamas-Saiz

  89. Understanding the Key Factors that Control the Inhibition of Type II Dehydroquinase by (2R)‐2‐Benzyl‐3‐dehydroquinic Acids

    Article • ChemMedChem, September 2010, Wiley

    Concepcion Gonzalez-Bello, Dr Antonio L Llamas-Saiz

  90. ChemInform Abstract: Synthesis of 4-Deoxyquinic, 4-Deoxyshikimic and 4-Deoxy-3-dehydroshikimic Acid.

    Article • ChemInform, June 2010, Wiley

    Concepcion Gonzalez-Bello

  91. Functional desymmetrization of 1,3-dioximes for the obtention of 1,2,3-hetero trisubstituted carbocycles

    Article • Tetrahedron Letters, April 2010, Elsevier

    Dr Ravi Varala, Concepcion Gonzalez-Bello

  92. Chiral Aziridination of Olefins Using a Chiral Sulfinamide as the Nitrogen Source

    Article • Synlett, December 2009, Thieme Publishing Group

    Dr Vasco Bonifácio, Concepcion Gonzalez-Bello

  93. Synthesis and Biological Evaluation of New Nanomolar Competitive Inhibitors of Helicobacter pylori Type II Dehydroquinase. Structural Details of the Role of the Aromatic Moieties with Essential Residues

    Article • Journal of Medicinal Chemistry, November 2009, American Chemical Society (ACS)

    Concepcion Gonzalez-Bello, Dr Antonio L Llamas-Saiz

  94. 2-Substituted-3-Dehydroquinic Acids as Potent Competitive Inhibitors of Type II Dehydroquinase

    Article • ChemMedChem, October 2009, Wiley

    Concepcion Gonzalez-Bello

  95. A selective resin for trans-diequatorial-1,2-diols

    Article • Tetrahedron Letters, April 2009, Elsevier

    Concepcion Gonzalez-Bello

  96. ChemInform Abstract: The Conformational Rigidity of Butane-1,2-diacetals as a Powerful Synthetic Tool

    Article • ChemInform, November 2008, Wiley

    Concepcion Gonzalez-Bello

  97. Stereoselective Synthesis of Novel Cyclic γ-Amino Acids and Triazole Derivatives

    Article • European Journal of Organic Chemistry, August 2008, Wiley

    Concepcion Gonzalez-Bello

  98. Competitive Inhibitors of Helicobacter pylori Type II Dehydroquinase: Synthesis, Biological Evaluation, and NMR Studies

    Article • ChemMedChem, May 2008, Wiley

    Concepcion Gonzalez-Bello

  99. Editorial [ The Medicinal Chemistry of Anti-Infectious Agents Guest Editor: Concepcion Gonzalez-Bello ]

    Article • Current Topics in Medicinal Chemistry, April 2008, Bentham Science Publishers

    Concepcion Gonzalez-Bello

  100. The conformational rigidity of butane-1,2-diacetals as a powerful synthetic tool

    Article • Chemical Society Reviews, January 2008, Royal Society of Chemistry

    Concepcion Gonzalez-Bello

  101. Progress in Type II Dehydroquinase Inhibitors: From Concept to Practice

    Article • ChemInform, June 2007, Wiley

    Concepcion Gonzalez-Bello

  102. Nanomolar Competitive Inhibitors of Mycobacterium tuberculosis and Streptomyces coelicolor Type II Dehydroquinase

    Article • ChemMedChem, January 2007, Wiley

    Concepcion Gonzalez-Bello, Dr Alan Riboldi-Tunnicliffe

  103. Cover Picture: Nanomolar Competitive Inhibitors of Mycobacterium tuberculosis and Streptomyces coelicolor Type II Dehydroquinase (ChemMedChem 2/2007)

    Article • ChemMedChem, January 2007, Wiley

    Concepcion Gonzalez-Bello, Dr Alan Riboldi-Tunnicliffe

  104. Nanomolar Inhibition of Type II Dehydroquinase Based on the Enolate Reaction Mechanism

    Article • ChemMedChem, January 2007, Wiley

    Concepcion Gonzalez-Bello

  105. Progress in type II dehydroquinase inhibitors: From concept to practice

    Article • Medicinal Research Reviews, January 2007, Wiley

    Concepcion Gonzalez-Bello

  106. Determination of the Bound Conformation of a Competitive Nanomolar Inhibitor of Mycobacterium tuberculosis Type II Dehydroquinase by NMR Spectroscopy

    Article • ChemMedChem, September 2006, Wiley

    Concepcion Gonzalez-Bello

  107. Synthesis of Spiro Carba-Sugars by Ring-Closing Metathesis

    Article • European Journal of Organic Chemistry, February 2006, Wiley

    Concepcion Gonzalez-Bello

  108. Structure-Based Design, Synthesis, and Biological Evaluation of Inhibitors of Mycobacterium tuberculosis Type II Dehydroquinase

    Article • Journal of Medicinal Chemistry, June 2005, American Chemical Society (ACS)

    Concepcion Gonzalez-Bello

  109. Rational design of new bifunctional inhibitors of type II dehydroquinase

    Article • Organic & Biomolecular Chemistry, January 2005, Royal Society of Chemistry

    Concepcion Gonzalez-Bello

  110. Synthesis of Amino Carba Sugars and Conformationally Restricted Polyhydroxyγ-Amino Acids from (−)-Quinic Acid

    Article • European Journal of Organic Chemistry, September 2004, Wiley

    Concepcion Gonzalez-Bello

  111. Parallel Solid-Phase Synthesis and Evaluation of Inhibitors of Streptomyces coelicolor Type II Dehydroquinase

    Article • Journal of Medicinal Chemistry, November 2003, American Chemical Society (ACS)

    Concepcion Gonzalez-Bello

  112. Synthesis of Polyhydroxycyclohexanes and Relatives from (−)-Quinic Acid

    Article • The Journal of Organic Chemistry, February 2003, American Chemical Society (ACS)

    Concepcion Gonzalez-Bello

  113. Mild, Aprotic Synthesis of 1,2‐Diacetals.

    Article • ChemInform, January 2003, Wiley

    Concepcion Gonzalez-Bello

  114. Design, synthesis and evaluation of bifunctional inhibitors of type II dehydroquinase

    Article • Organic & Biomolecular Chemistry, January 2003, Royal Society of Chemistry

    Concepcion Gonzalez-Bello

  115. Mild, aprotic synthesis of 1,2-diacetals

    Article • Tetrahedron Letters, October 2002, Elsevier

    Concepcion Gonzalez-Bello

  116. ChemInform Abstract: Synthesis of Carba‐Sugars from (‐)‐Quinic Acid.

    Article • ChemInform, September 2001, Wiley

    Concepcion Gonzalez-Bello

  117. Synthesis of carba-sugars from (−)-quinic acid

    Article • Tetrahedron Letters, June 2001, Elsevier

    Concepcion Gonzalez-Bello

  118. Benzenediazonium-2-carboxylate

    Article • April 2001, Wiley

    Concepcion Gonzalez-Bello

  119. Irreversible inhibition of type I dehydroquinase by substrates for type II dehydroquinase

    Article • Bioorganic & Medicinal Chemistry Letters, March 2000, Elsevier

    Concepcion Gonzalez-Bello

  120. Mechanistic studies on type I and type II dehydroquinase with (6 R )- and (6 S )-6-fluoro-3-dehydroquinic acids

    Article • Bioorganic & Medicinal Chemistry Letters, February 2000, Elsevier

    Concepcion Gonzalez-Bello

  121. Synthesis of phenanthridones, quinolinequinones and 7-azasteroids

    Article • Tetrahedron, April 1999, Elsevier

    Concepcion Gonzalez-Bello

  122. Synthesis of 4-deoxyquinic, 4-deoxyshikimic and 4-deoxy-3-dehydroshikimic acids

    Article • Journal of the Chemical Society Perkin Transactions 1, January 1999, Royal Society of Chemistry

    Concepcion Gonzalez-Bello

  123. Synthesis of 2-Bromo- and 2-Fluoro-3-dehydroshikimic Acids and 2-Bromo- and 2-Fluoroshikimic Acids Using Synthetic and Enzymatic Approaches

    Article • The Journal of Organic Chemistry, February 1998, American Chemical Society (ACS)

    Concepcion Gonzalez-Bello

  124. Synthesis of (2R)-2-bromodehydroquinic acid and (2R)-2-fluorodehydroquinic acid

    Article • Journal of the Chemical Society Perkin Transactions 1, January 1997, Royal Society of Chemistry

    Concepcion Gonzalez-Bello

  125. Synthesis of tetrahydroquinolines, hexahydrobenzoindolizines and an aryl phosphonate linker for the generation of catalytic antibodies

    Article • Journal of the Chemical Society Perkin Transactions 1, January 1997, Royal Society of Chemistry

    Concepcion Gonzalez-Bello

  126. Evidence from kinetic isotope studies for an enolate intermediate in the mechanism of type II dehydroquinases

    Article • Biochemical Journal, October 1996, Portland Press Ltd.

    Concepcion Gonzalez-Bello

  127. A new intramolecular aryne cycloaddition approach to lycorines

    Article • Tetrahedron Letters, January 1996, Elsevier

    Concepcion Gonzalez-Bello

  128. Synthesis of lycorines by intramolecular aryne cycloadditions

    Article • The Journal of Organic Chemistry, October 1995, American Chemical Society (ACS)

    Concepcion Gonzalez-Bello

  129. Total Synthesis of (-)-Neplanocin A from L-Ribulose

    Article • Synlett, January 1991, Thieme Publishing Group

    Concepcion Gonzalez-Bello

  130. New Methods for Synthesis of Amaryllidaceae Alkaloids

    Article • Planta Medica, December 1990, Thieme Publishing Group

    Concepcion Gonzalez-Bello