All Stories

  1. The fetus at the tipping point: modifying the outcome of fetal asphyxia

    Article • The Journal of Physiology, June 2018, Wiley

    Dr Christopher Arthur Lear, Nicola Robertson, Alistair Gunn

  2. A working model for hypothermic neuroprotection

    Article • The Journal of Physiology, May 2018, Wiley

    Dr Christopher Arthur Lear, Alistair Gunn

  3. The peripheral chemoreflex: indefatigable guardian of fetal physiological adaptation to labour

    Article • The Journal of Physiology, April 2018, Wiley

    Dr Christopher Arthur Lear, Jenny Westgate, Alistair Gunn

  4. Time and sex dependent effects of magnesium sulphate on post-asphyxial seizures in preterm fetal sheep

    Article • The Journal of Physiology, April 2018, Wiley

    Dr Christopher Arthur Lear, Alistair Gunn

  5. Chronic inflammation and impaired development of the preterm brain

    Article • Journal of Reproductive Immunology, February 2018, Elsevier

    Dr Christopher Arthur Lear

  6. Evolving changes in fetal heart rate variability and brain injury after hypoxia-ischaemia in preterm fetal sheep

    Article • The Journal of Physiology, January 2018, Wiley

    Dr Christopher Arthur Lear, Alistair Gunn

  7. Complex interactions between hypoxia-ischemia and inflammation in preterm brain injury

    Article • Developmental Medicine & Child Neurology, December 2017, Wiley

    Dr Christopher Arthur Lear, Alistair Gunn

  8. An investigation of fetal behavioural states during maternal sleep in healthy late gestation pregnancy: an observational study

    Article • The Journal of Physiology, November 2017, Wiley

    Alistair Gunn, Dr Christopher Arthur Lear

  9. Delayed intranasal infusion of human amnion epithelial cells improves white matter maturation after asphyxia in preterm fetal sheep

    Article • Journal of Cerebral Blood Flow & Metabolism, September 2017, SAGE Publications

    Dr Christopher Arthur Lear, Alistair Gunn

  10. Reply from Christopher A. Lear, Robert Galinsky, Guido Wassink, Kyohei Yamaguchi, Joanne O. Davidson, Jenny A. Westgate, Laura Bennet and Alistair J. Gunn

    Article • The Journal of Physiology, August 2017, Wiley

    Alistair Gunn, Jenny Westgate, Dr Christopher Arthur Lear

  11. Connexin hemichannel blockade improves survival of striatal GABA-ergic neurons after global cerebral ischaemia in term-equivalent fetal sheep

    Article • Scientific Reports, July 2017, Nature

    Dr Christopher Arthur Lear, Alistair Gunn

  12. Antenatal dexamethasone before asphyxia promotes cystic neural injury in preterm fetal sheep by inducing hyperglycemia

    Article • Journal of Cerebral Blood Flow & Metabolism, April 2017, SAGE Publications

    Dr Christopher Arthur Lear, Alistair Gunn

  13. In the Era of Therapeutic Hypothermia, How Well Do Studies of Perinatal Neuroprotection Control Temperature?

    Article • Developmental Neuroscience, December 2016, Karger Publishers

    Dr Christopher Arthur Lear, Alistair Gunn

  14. Effect of maternal position on fetal behavioural state and heart rate variability in healthy late gestation pregnancy

    Article • The Journal of Physiology, December 2016, Wiley

    Dr Christopher Arthur Lear, Alistair Gunn

  15. Cholinergic and β-adrenergic control of cardiovascular reflex responses to brief repeated asphyxia in term-equivalent fetal sheep

    Article • AJP Regulatory Integrative and Comparative Physiology, November 2016, American Physiological Society

    Dr Christopher Arthur Lear, Alistair Gunn

  16. Magnesium sulfate reduces EEG activity but is not neuroprotective after asphyxia in preterm fetal sheep

    Article • Journal of Cerebral Blood Flow & Metabolism, July 2016, SAGE Publications

    Dr Christopher Arthur Lear

  17. The myths and physiology surrounding intrapartum decelerations: the critical role of the peripheral chemoreflex

    Article • The Journal of Physiology, May 2016, Wiley

    Alistair Gunn, Dr Christopher Arthur Lear

  18. Subclinical decelerations during developing hypotension in preterm fetal sheep after acute on chronic lipopolysaccharide exposure

    Article • Scientific Reports, November 2015, Nature

    Dr Christopher Arthur Lear, Alistair Gunn

  19. Potential neuroprotective strategies for perinatal infection and inflammation

    Article • International Journal of Developmental Neuroscience, October 2015, Elsevier

    Dr Christopher Arthur Lear, Alistair Gunn

  20. Magnesium sulphate and cardiovascular and cerebrovascular adaptations to asphyxia in preterm fetal sheep

    Article • The Journal of Physiology, July 2015, Wiley

    Alistair Gunn, Dr Christopher Arthur Lear

  21. Sympathetic neural activation does not mediate heart rate variability during repeated brief umbilical cord occlusions in near-term fetal sheep

    Article • The Journal of Physiology, May 2015, Wiley

    Alistair Gunn, Dr Christopher Arthur Lear

  22. Analgesics, sedatives, anticonvulsant drugs, and the cooled brain

    Article • Seminars in Fetal and Neonatal Medicine, April 2015, Elsevier

    Dr Christopher Arthur Lear, Alistair Gunn

  23. The effects of dexamethasone on post‐asphyxial cerebral oxygenation in the preterm fetal sheep

    Article • The Journal of Physiology, November 2014, Wiley

    Dr Christopher Arthur Lear, Alistair Gunn

  24. Biphasic changes in fetal heart rate variability in preterm fetal sheep developing hypotension after acute on chronic lipopolysaccharide exposure

    Article • AJP Regulatory Integrative and Comparative Physiology, June 2014, American Physiological Society

    Dr Christopher Arthur Lear, Alistair Gunn

  25. Synergistic white matter protection with acute-on-chronic endotoxin and subsequent asphyxia in preterm fetal sheep

    Article • Journal of Neuroinflammation, January 2014, Springer Science + Business Media

    Dr Christopher Arthur Lear, Alistair Gunn

  26. Magnesium Is Not Consistently Neuroprotective for Perinatal Hypoxia-Ischemia in Term-Equivalent Models in Preclinical Studies: A Systematic Review

    Article • Developmental Neuroscience, January 2014, Karger Publishers

    Dr Christopher Arthur Lear, Alistair Gunn