All Stories

  1. MeHg‐Induced Cytotoxicity Associated With Oxidative Stress and Early Calcium Mobility in Rat Cerebral Cortical Astrocytes

    Article • Journal of Cellular Physiology, January 2026, Wiley

    Dr Chienchih Chiu

  2. Artificial Intelligence‐Based In Silico Evaluation of the Pharmacological Potential and In Vitro Anti‐Malignancy Effect in the Human Glioblastoma Cell Line of the Hydrate of the Coumarin Compound Meranzin Originating From the Edible Macroalga ( ...

    Article • Food Science & Nutrition, December 2025, Wiley

    Dr Chienchih Chiu

  3. The Beneficial Effect of the SGLT2 Inhibitor Dapagliflozin in Alleviating Acute Myocardial Infarction-Induced Cardiomyocyte Injury by Increasing the Sirtuin Family SIRT1/SIRT3 and Cascade Signaling

    Article • International Journal of Molecular Sciences, August 2024, MDPI AG

    Dr Chienchih Chiu

  4. The Role of Long Noncoding RNAs (lncRNAs) in Esophageal Cancer Therapy Resistance and Metastasis

    Article • Biomedicines, March 2024, MDPI AG

    Dr Chienchih Chiu

  5. MicroRNA-320a enhances LRWD1 expression through the AGO2/FXR1-dependent pathway to affect cell behaviors and the oxidative stress response in human testicular embryonic carcinoma cells

    Article • Aging, February 2024, Impact Journals, LLC

    Dr Chienchih Chiu

  6. Melanoma biology and treatment: a review of novel regulated cell death-based approaches

    Article • Cancer Cell International, February 2024, Springer Science + Business Media

    Dr Chienchih Chiu

  7. Immunotherapy Study on Non-small-Cell Lung Cancer (NSCLC) Combined with Cytotoxic T Cells and miRNA34a

    Article • Molecular Pharmaceutics, January 2024, American Chemical Society (ACS)

    Dr Chienchih Chiu

  8. Mitochondrial Signaling, the Mechanisms of AKI-to-CKD Transition and Potential Treatment Targets

    Article • International Journal of Molecular Sciences, January 2024, MDPI AG

    Dr Chienchih Chiu

  9. Exploring the potential of dual-sensitive hydrogels for personalized precision medicine applications

    Article • Journal of the Taiwan Institute of Chemical Engineers, December 2023, Elsevier

    Dr Chienchih Chiu

  10. Intravitreal Aflibercept for Patients with Acute Nonarteritic Anterior Ischemic Optic Neuropathy: A Retrospective Trial

    Article • Journal of Clinical Medicine, July 2023, MDPI AG

    Dr Chienchih Chiu

  11. The Pyroptotic and Nonpyroptotic Roles of Gasdermins in Modulating Cancer Progression and Their Perspectives on Cancer Therapeutics

    Article • Archivum Immunologiae et Therapiae Experimentalis, May 2023, De Gruyter

    Dr Chienchih Chiu

  12. Diphenyl disulfide potentiates the apoptosis of breast cancer cells through Bax proteolytic activation with accompanying autophagy

    Article • Environmental Toxicology, May 2023, Wiley

    Dr Chienchih Chiu

  13. The Role of Exosomes in Pancreatic Ductal Adenocarcinoma Progression and Their Potential as Biomarkers

    Article • Cancers, March 2023, MDPI AG

    Dr Chienchih Chiu

  14. Comparing the Variants of Iron Oxide Nanoparticle-Mediated Delivery of miRNA34a for Efficiency in Silencing of PD-L1 Genes in Cancer Cells

    Article • Pharmaceutics, January 2023, MDPI AG

    Dr Chienchih Chiu

  15. Phthalate derivative DEHP disturbs the antiproliferative effect of camptothecin in human lung cancer cells by attenuating DNA damage and activating Akt/ NF‐κB ...

    Article • Environmental Toxicology, November 2022, Wiley

    Ritesh Urade, Dr Chienchih Chiu

  16. Neuropeptide-Functionalized Gold Nanorod Enhanced Cellular Uptake and Improved In Vitro Photothermal Killing in LRP1-Positive Glioma Cells

    Article • Pharmaceutics, September 2022, MDPI AG

    Dr Chienchih Chiu

  17. Punicalagin Attenuates LPS-Induced Inflammation and ROS Production in Microglia by Inhibiting the MAPK/NF-κB Signaling Pathway and NLRP3 Inflammasome Activation

    Article • Journal of Inflammation Research, September 2022, Taylor & Francis

    Dr Chienchih Chiu

  18. Cordyceps militaris Reduces Oxidative Stress and Regulates Immune T Cells to Inhibit Metastatic Melanoma Invasion

    Article • Antioxidants, July 2022, MDPI AG

    Dr Chienchih Chiu

  19. Nitrobenzoate-Derived Compound X8 Impairs Vascular Development in Zebrafish

    Article • International Journal of Molecular Sciences, July 2022, MDPI AG

    Dr Chienchih Chiu

  20. Identification of Novel Vascular Genes Downstream of Islet2 and Nr2f1b Transcription Factors

    Article • Biomedicines, May 2022, MDPI AG

    Dr Chienchih Chiu

  21. diTFPP, a Phenoxyphenol, Sensitizes Hepatocellular Carcinoma Cells to C2-Ceramide-Induced Autophagic Stress by Increasing Oxidative Stress and ER Stress Accompanied by LAMP2 Hypoglycosylation

    Article • Cancers, May 2022, MDPI AG

    Dr Chienchih Chiu

  22. Small GTPases and Their Regulators: A Leading Road toward Blood Vessel Development in Zebrafish

    Article • International Journal of Molecular Sciences, April 2022, MDPI AG

    Dr Chienchih Chiu

  23. Zebrafish Model-Based Assessment of Indoxyl Sulfate-Induced Oxidative Stress and Its Impact on Renal and Cardiac Development

    Article • Antioxidants, February 2022, MDPI AG

    Dr Chienchih Chiu

  24. Endoglin Modulates TGFβR2 Induced VEGF and Proinflammatory Cytokine Axis Mediated Angiogenesis in Prolonged DEHP-Exposed Breast Cancer Cells

    Article • Biomedicines, February 2022, MDPI AG

    Dr Chienchih Chiu

  25. The Adverse Effects of Air Pollution on the Eye: A Review

    Article • International Journal of Environmental Research and Public Health, January 2022, MDPI AG

    Dr Chienchih Chiu

  26. Kinome-Wide siRNA Screening Identifies DYRK1B as a Potential Therapeutic Target for Triple-Negative Breast Cancer Cells

    Article • Cancers, November 2021, MDPI AG

    Dr Chienchih Chiu

  27. Nepenthes Extract Induces Selective Killing, Necrosis, and Apoptosis in Oral Cancer Cells

    Article • Journal of Personalized Medicine, August 2021, MDPI AG

    Dr Chienchih Chiu

  28. New Insight into the Effects of Metformin on Diabetic Retinopathy, Aging and Cancer: Nonapoptotic Cell Death, Immunosuppression, and Effects beyond the AMPK Pathway

    Article • International Journal of Molecular Sciences, August 2021, MDPI AG

    Dr Chienchih Chiu

  29. Mycotoxin Zearalenone Attenuates Innate Immune Responses and Suppresses NLRP3 Inflammasome Activation in LPS-Activated Macrophages

    Article • Toxins, August 2021, MDPI AG

    Dr Chienchih Chiu

  30. The Long-Term DEHP Exposure Confers Multidrug Resistance of Triple-Negative Breast Cancer Cells through ABC Transporters and Intracellular ROS

    Article • Antioxidants, June 2021, MDPI AG

    Dr Chienchih Chiu

  31. Oxidative Stress-Dependent Synergistic Antiproliferation, Apoptosis, and DNA Damage of Ultraviolet-C and Coral-Derived Sinularin Combined Treatment for Oral Cancer Cells

    Article • Cancers, May 2021, MDPI AG

    Dr Chienchih Chiu

  32. The Phenoxyphenol Compound diTFPP Mediates Exogenous C2-Ceramide Metabolism, Inducing Cell Apoptosis Accompanied by ROS Formation and Autophagy in Hepatocellular Carcinoma Cells

    Article • Antioxidants, March 2021, MDPI AG

    Dr Chienchih Chiu

  33. The Role of Oxidative Stress and Autophagy in Blue-Light-Induced Damage to the Retinal Pigment Epithelium in Zebrafish In Vitro and In Vivo

    Article • International Journal of Molecular Sciences, January 2021, MDPI AG

    Dr Chienchih Chiu

  34. Curcumin Metabolite Tetrahydrocurcumin in the Treatment of Eye Diseases

    Article • International Journal of Molecular Sciences, December 2020, MDPI AG

    Dr Chienchih Chiu

  35. Direct Binding of Cisplatin to p22phox, an Endoplasmic Reticulum (ER) Membrane Protein, Contributes to Cisplatin Resistance in Oral Squamous Cell Carcinoma (OSCC) Cells

    Article • Molecules, August 2020, MDPI AG

    Dr Chienchih Chiu

  36. The Role of Necroptosis in ROS-Mediated Cancer Therapies and Its Promising Applications

    Article • Cancers, August 2020, MDPI AG

    Dr Chienchih Chiu

  37. Purified Astaxanthin from Haematococcus pluvialis Promotes Tissue Regeneration by Reducing Oxidative Stress and the Secretion of Collagen In Vitro and In Vivo

    Article • Oxidative Medicine and Cellular Longevity, August 2020, Hindawi Publishing Corporation

    Dr Chienchih Chiu

  38. DFIQ, a Novel Quinoline Derivative, Shows Anticancer Potential by Inducing Apoptosis and Autophagy in NSCLC Cell and In Vivo Zebrafish Xenograft Models

    Article • Cancers, May 2020, MDPI AG

    Dr Chienchih Chiu

  39. The Phenoxyphenol Compound 4-HPPP Selectively Induces Antiproliferation Effects and Apoptosis in Human Lung Cancer Cells through Aneupolyploidization and ATR DNA Repair Signaling

    Article • Oxidative Medicine and Cellular Longevity, January 2020, Hindawi Publishing Corporation

    Dr Chienchih Chiu

  40. C2-Ceramide-Induced Rb-Dominant Senescence-Like Phenotype Leads to Human Breast Cancer MCF-7 Escape from p53-Dependent Cell Death

    Article • International Journal of Molecular Sciences, September 2019, MDPI AG

    Dr Chienchih Chiu

  41. MicroRNA-21 Mediates the Protective Effect of Cardiomyocyte-Derived Conditioned Medium on Ameliorating Myocardial Infarction in Rats

    Article • Cells, August 2019, MDPI AG

    Dr Chienchih Chiu

  42. Unfolded Protein Response (UPR) in Survival, Dormancy, Immunosuppression, Metastasis, and Treatments of Cancer Cells

    Article • International Journal of Molecular Sciences, May 2019, MDPI AG

    Dr Chienchih Chiu

  43. Combination Therapy of Chloroquine and C2-Ceramide Enhances Cytotoxicity in Lung Cancer H460 and H1299 Cells

    Article • Cancers, March 2019, MDPI AG

    Dr Chienchih Chiu

  44. Reduced camptothecin sensitivity of estrogen receptor‐positive human breast cancer cells following exposure to di(2‐ethylhexyl)phthalate (DEHP) is associated with DNA methylation changes

    Article • Environmental Toxicology, February 2019, Wiley

    Shih-Shin Liang, Dr Chienchih Chiu

  45. Protective Effects of Lycium barbarum Extracts on UVB-Induced Damage in Human Retinal Pigment Epithelial Cells Accompanied by Attenuating ROS and DNA Damage

    Article • Oxidative Medicine and Cellular Longevity, November 2018, Hindawi Publishing Corporation

    Dr Chienchih Chiu

  46. Exogenous C8-Ceramide Induces Apoptosis by Overproduction of ROS and the Switch of Superoxide Dismutases SOD1 to SOD2 in Human Lung Cancer Cells

    Article • International Journal of Molecular Sciences, October 2018, MDPI AG

    Dr Chienchih Chiu

  47. Ethyl Acetate Extract of Scindapsus cf. hederaceus Exerts the Inhibitory Bioactivity on Human Non-Small Cell Lung Cancer Cells through Modulating ER Stress

    Article • International Journal of Molecular Sciences, June 2018, MDPI AG

    Dr Chienchih Chiu

  48. The Effect of Bornyl cis-4-Hydroxycinnamate on Melanoma Cell Apoptosis Is Associated with Mitochondrial Dysfunction and Endoplasmic Reticulum Stress

    Article • International Journal of Molecular Sciences, May 2018, MDPI AG

    Dr Chienchih Chiu

  49. The Impact of Di(2-ethylhexyl)phthalate on Cancer Progression

    Article • Archivum Immunologiae et Therapiae Experimentalis, December 2017, De Gruyter

    Dr Chienchih Chiu

  50. Coral-Derived Natural Marine Compound GB9 Impairs Vascular Development in Zebrafish

    Article • International Journal of Molecular Sciences, August 2017, MDPI AG

    Dr Chienchih Chiu

  51. A 4-Phenoxyphenol Derivative Exerts Inhibitory Effects on Human Hepatocellular Carcinoma Cells through Regulating Autophagy and Apoptosis Accompanied by Downregulating α-Tubulin Expression

    Article • Molecules, May 2017, MDPI AG

    Dr Chienchih Chiu

  52. The Potential Role of Krüppel-Like Zinc-Finger Protein Glis3 in Genetic Diseases and Cancers

    Article • Archivum Immunologiae et Therapiae Experimentalis, May 2017, De Gruyter

    Dr Chienchih Chiu

  53. 9-bis[2-(pyrrolidin-1-yl)ethoxy]-6-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}-11H-indeno[1, 2-c]quinolin-11-one (BPIQ), A Quinoline Derivative Inhibits Human Hepatocellular Carcinoma Cells by Inducing ER Stress and Apoptosis

    Article • Anti-Cancer Agents in Medicinal Chemistry, April 2017, Bentham Science Publishers

    Dr Chienchih Chiu

  54. Correction: Chon-Kit Chou, et al. The Regulations of Deubiquitinase USP15 and Its Pathophysiological Mechanisms in Diseases. Int. J. Mol. Sci. 2017, 18, 483

    Article • International Journal of Molecular Sciences, April 2017, MDPI AG

    Dr Chienchih Chiu

  55. The Regulations of Deubiquitinase USP15 and Its Pathophysiological Mechanisms in Diseases

    Article • International Journal of Molecular Sciences, February 2017, MDPI AG

    Dr Chienchih Chiu

  56. Ftr82 Is Critical for Vascular Patterning during Zebrafish Development

    Article • International Journal of Molecular Sciences, January 2017, MDPI AG

    Dr Chienchih Chiu

  57. Cytotoxicity of 11-epi-Sinulariolide Acetate Isolated from Cultured Soft Corals on HA22T Cells through the Endoplasmic Reticulum Stress Pathway and Mitochondrial Dysfunction

    Article • International Journal of Molecular Sciences, October 2016, MDPI AG

    Dr Chienchih Chiu

  58. Inhibitory effect of trans-ferulic acid on proliferation and migration of human lung cancer cells accompanied with increased endogenous reactive oxygen species and β-catenin instability

    Article • Chinese Medicine, October 2016, Springer Science + Business Media

    Dr Chienchih Chiu

  59. A Quinone-Containing Compound Enhances Camptothecin-Induced Apoptosis of Lung Cancer Through Modulating Endogenous ROS and ERK Signaling

    Article • Archivum Immunologiae et Therapiae Experimentalis, September 2016, De Gruyter

    Dr Chienchih Chiu

  60. A novel role for β2-microglobulin: a precursor of antibacterial chemokine in respiratory epithelial cells

    Article • Scientific Reports, August 2016, Springer Science + Business Media

    Dr Chienchih Chiu

  61. Reductive amination-assisted quantitation of tamoxifen and its metabolites by liquid phase chromatography tandem mass spectrometry

    Article • Journal of Chromatography A, February 2016, Elsevier

    Dr Chienchih Chiu

  62. A novel cell-penetrating peptide suppresses breast tumorigenesis by inhibiting β-catenin/LEF-1 signaling

    Article • Scientific Reports, January 2016, Springer Science + Business Media

    Dr Chienchih Chiu, Cheng Yu Long

  63. An Acetamide Derivative as a Camptothecin Sensitizer for Human Non-Small-Cell Lung Cancer Cells through Increased Oxidative Stress and JNK Activation

    Article • Oxidative Medicine and Cellular Longevity, January 2016, Hindawi Publishing Corporation

    Dr Chienchih Chiu

  64. Biofunctional Activities ofEquisetum ramosissimumExtract: Protective Effects against Oxidation, Melanoma, and Melanogenesis

    Article • Oxidative Medicine and Cellular Longevity, January 2016, Hindawi Publishing Corporation

    Dr Chienchih Chiu

  65. Discovery of indeno[1,2- b ]quinoxaline derivatives as potential anticancer agents

    Article • European Journal of Medicinal Chemistry, January 2016, Elsevier

    Dr Chienchih Chiu

  66. Distinct CPT-induced deaths in lung cancer cells caused by clathrin-mediated internalization of CP micelles

    Article • Nanoscale, January 2016, Royal Society of Chemistry

    Dr Chienchih Chiu

  67. BPIQ, a novel synthetic quinoline derivative, inhibits growth and induces mitochondrial apoptosis of lung cancer cells in vitro and in zebrafish xenograft model

    Article • BMC Cancer, December 2015, Springer Science + Business Media

    Dr Chienchih Chiu

  68. Curcumin Suppresses Phthalate-Induced Metastasis and the Proportion of Cancer Stem Cell (CSC)-like Cells via the Inhibition of AhR/ERK/SK1 Signaling in Hepatocellular Carcinoma

    Article • Journal of Agricultural and Food Chemistry, December 2015, American Chemical Society (ACS)

    Dr Chienchih Chiu

  69. Quinoline-Based Compound BPIQ Exerts Anti-Proliferative Effects on Human Retinoblastoma Cells via Modulating Intracellular Reactive Oxygen Species

    Article • Archivum Immunologiae et Therapiae Experimentalis, November 2015, De Gruyter

    Dr Chienchih Chiu

  70. Reactive oxygen species mediate Terbufos-induced apoptosis in mouse testicular cell lines via the modulation of cell cycle and pro-apoptotic proteins

    Article • Environmental Toxicology, September 2015, Wiley

    Dr Chienchih Chiu

  71. An indolylquinoline derivative promotes apoptosis in human lung cancer cells by impairing mitochondrial functions

    Article • APOPTOSIS, September 2015, Springer Science + Business Media

    Dr Chienchih Chiu

  72. 4-(Phenylsulfanyl)butan-2-One Suppresses Melanin Synthesis and Melanosome Maturation In Vitro and In Vivo

    Article • International Journal of Molecular Sciences, August 2015, MDPI AG

    Dr Chienchih Chiu

  73. 7-Hydroxydehydronuciferine induces human melanoma death via triggering autophagy and apoptosis

    Article • Experimental Dermatology, August 2015, Wiley

    Dr Chienchih Chiu

  74. Folic Acid Linked Chondroitin Sulfate-Polyethyleneimine Copolymer Based Gene Delivery System

    Article • Journal of Biomedical Nanotechnology, August 2015, American Scientific Publishers

    Dr Chienchih Chiu

  75. BubR1 Acts as a Promoter in Cellular Motility of Human Oral Squamous Cancer Cells through Regulating MMP-2 and MMP-9

    Article • International Journal of Molecular Sciences, July 2015, MDPI AG

    Dr Chienchih Chiu

  76. Polygonum cuspidatum extracts as bioactive antioxidaion, anti-tyrosinase, immune stimulation and anticancer agents

    Article • Journal of Bioscience and Bioengineering, April 2015, Elsevier

    Dr Chienchih Chiu

  77. Chondroitin sulfate-polyethylenimine copolymer-coated superparamagnetic iron oxide nanoparticles as an efficient magneto-gene carrier for microRNA-encoding plasmid DNA delivery

    Article • Nanoscale, January 2015, Royal Society of Chemistry

    Professor Lifang Wang, Dr Chienchih Chiu

  78. Discovery of 2-[2-(5-nitrofuran-2-yl)vinyl]quinoline derivatives as a novel type of antimetastatic agents

    Article • Bioorganic & Medicinal Chemistry, January 2015, Elsevier

    Dr Chienchih Chiu

  79. Brefeldin A Reduces Anchorage-Independent Survival, Cancer Stem Cell Potential and Migration of MDA-MB-231 Human Breast Cancer Cells

    Article • Molecules, October 2014, MDPI AG

    Dr Chienchih Chiu

  80. Correlation between leucine rich domain and the stability of LRWD1 protein in human NT2/D1 cells

    Article • Advances in Medical Sciences, September 2014, Elsevier

    Dr Chienchih Chiu

  81. Nuclear Receptor Subfamily 2 Group F Member 1a (nr2f1a) Is Required for Vascular Development in Zebrafish

    Article • PLOS One, August 2014, PLOS

    Dr Chienchih Chiu

  82. Involvement of p38 mitogen-activated protein kinase in acquired gemcitabine-resistant human urothelial carcinoma sublines

    Article • The Kaohsiung Journal of Medical Sciences, July 2014, Wiley

    WEI CHI HSU, Dr Chienchih Chiu

  83. Cardiotoxin III suppresses hepatocyte growth factor-stimulated migration and invasion of MDA-MB-231 cells

    Article • Cell Biochemistry and Function, June 2014, Wiley

    Dr Chienchih Chiu

  84. Preparation of Chondroitin Sulfate-g-poly(ε-caprolactone) Copolymers as a CD44-Targeted Vehicle for Enhanced Intracellular Uptake

    Article • Molecular Pharmaceutics, March 2014, American Chemical Society (ACS)

    Dr Chienchih Chiu

  85. The antiproliferative effect of C2-ceramide on lung cancer cells through apoptosis by inhibiting Akt and NFκB

    Article • Cancer Cell International, January 2014, Springer Science + Business Media

    Dr Chienchih Chiu

  86. Synthesis and antiproliferative evaluation of 9-methoxy-6-(piperazin-1-yl)-11H-indeno[1,2-c]quinoline-11-one derivatives. Part 4

    Article • MedChemComm, January 2014, Royal Society of Chemistry

    Dr Chienchih Chiu

  87. Progesterone Increases Apoptosis and Inversely Decreases Autophagy in Human Hepatoma HA22T/VGH Cells Treated with Epirubicin

    Article • The Scientific World JOURNAL, January 2014, Hindawi Publishing Corporation

    Dr Chienchih Chiu

  88. The Antiproliferative and Apoptotic Effects of Sirtinol, a Sirtuin Inhibitor on Human Lung Cancer Cells by Modulating Akt/β-Catenin-Foxo3A Axis

    Article • The Scientific World JOURNAL, January 2014, Hindawi Publishing Corporation

    Dr Chienchih Chiu

  89. Brefeldin A Inhibits Cancer Stem Cell Properties in Human Lung Cancer Cells

    Article • Current Signal Transduction Therapy, December 2013, Bentham Science Publishers

    Dr Chienchih Chiu

  90. Inhibition of Src activation with cardiotoxin III blocks migration and invasion of MDA-MB-231 cells

    Article • Toxicon, November 2013, Elsevier

    Dr Chienchih Chiu

  91. Teroxirone inhibited growth of human non-small cell lung cancer cells by activating p53

    Article • Toxicology and Applied Pharmacology, November 2013, Elsevier

    Dr Chienchih Chiu

  92. Alpinia oxyphylla Miq. bioactive extracts from supercritical fluid carbon dioxide extraction

    Article • Biochemical Engineering Journal, September 2013, Elsevier

    Dr Chienchih Chiu

  93. Brefeldin A Effectively Inhibits Cancer Stem Cell-Like Properties and MMP-9 Activity in Human Colorectal Cancer Colo 205 Cells

    Article • Molecules, August 2013, MDPI AG

    Dr Chienchih Chiu

  94. Magnolol induces apoptosis via caspase-independent pathways in non-small cell lung cancer cells

    Article • Archives of Pharmacal Research, August 2013, Springer Science + Business Media

    Professor Yung-Hsiang Chen, Dr Chienchih Chiu

  95. Dual-Incision Laparoscopic Surgery for Peritoneal Dialysis Catheter Implantation and Fixation: A Novel, Simple, and Safe Procedure

    Article • Journal of Laparoendoscopic & Advanced Surgical Techniques, August 2013, Mary Ann Liebert Inc

    Professor Chun-Nan Yeh, Dr Chienchih Chiu

  96. Feruloyl-l-arabinose attenuates migration, invasion and production of reactive oxygen species in H1299 lung cancer cells

    Article • Food and Chemical Toxicology, August 2013, Elsevier

    Dr Chienchih Chiu

  97. Proteomic Investigation of the Sinulariolide-Treated Melanoma Cells A375: Effects on the Cell Apoptosis through Mitochondrial-Related Pathway and Activation of Caspase Cascade

    Article • Marine Drugs, July 2013, MDPI AG

    Dr Chienchih Chiu

  98. Calreticulin, an endoplasmic reticulum-resident protein, is highly expressed and essential for cell proliferation and migration in oral squamous cell carcinoma

    Article • Oral Oncology, June 2013, Elsevier

    Dr Chienchih Chiu

  99. Golden Berry-Derived 4β-hydroxywithanolide E for Selectively Killing Oral Cancer Cells by Generating ROS, DNA Damage, and Apoptotic Pathways

    Article • PLOS One, May 2013, PLOS

    Dr Chienchih Chiu

  100. Reduction of RNA A‐to‐I editing in Drosophila acclimated to heat shock

    Article • The Kaohsiung Journal of Medical Sciences, April 2013, Wiley

    Dr Chienchih Chiu

  101. Transcribed pseudogene ψPPM1K generates endogenous siRNA to suppress oncogenic cell growth in hepatocellular carcinoma

    Article • Nucleic Acids Research, February 2013, Oxford University Press (OUP)

    Dr Chienchih Chiu

  102. Enhancements of Skin Cell Proliferations and Migrations via 6-Dehydrogingerdione

    Article • Journal of Agricultural and Food Chemistry, January 2013, American Chemical Society (ACS)

    Dr Chienchih Chiu

  103. Chemically Conjugating Polyethylenimine with Chondroitin Sulfate to Promote CD44-Mediated Endocytosis for Gene Delivery

    Article • Molecular Pharmaceutics, January 2013, American Chemical Society (ACS)

    Dr Chienchih Chiu

  104. Cardiotoxin III Inhibits Proliferation and Migration of Oral Cancer Cells through MAPK and MMP Signaling

    Article • The Scientific World JOURNAL, January 2013, Hindawi Publishing Corporation

    Dr Chienchih Chiu

  105. Lucidone Suppresses Hepatitis C Virus Replication by Nrf2-Mediated Heme Oxygenase-1 Induction

    Article • Antimicrobial Agents and Chemotherapy, December 2012, ASM Journals

    Dr Chienchih Chiu

  106. Cardiotoxin III suppresses MDA-MB-231 cell metastasis through the inhibition of EGF/EGFR-mediated signaling pathway

    Article • Toxicon, October 2012, Elsevier

    Dr Chienchih Chiu

  107. Cytotoxic effects of Echinacea purpurea flower extracts and cichoric acid on human colon cancer cells through induction of apoptosis

    Article • Journal of Ethnopharmacology, October 2012, Elsevier

    Dr Chienchih Chiu, Sheng-Dun Lin

  108. Proteomic profiling of the 11-dehydrosinulariolide-treated oral carcinoma cells Ca9–22: Effects on the cell apoptosis through mitochondrial-related and ER stress pathway

    Article • Journal of Proteomics, October 2012, Elsevier

    Dr Chienchih Chiu

  109. Combretastatin A-4 derivatives: synthesis and evaluation of 2,4,5-triaryl-1H-imidazoles as potential agents against H1299 (non-small cell lung cancer cell)

    Article • Molecular Diversity, September 2012, Springer Science + Business Media

    Dr Chienchih Chiu

  110. Antiproliferative effects of goniothalamin on Ca9-22 oral cancer cells through apoptosis, DNA damage and ROS induction

    Article • Mutation Research/Genetic Toxicology and Environmental Mutagenesis, September 2012, Elsevier

    Dr Chienchih Chiu

  111. Induction of Apoptosis by 11-Dehydrosinulariolide via Mitochondrial Dysregulation and ER Stress Pathways in Human Melanoma Cells

    Article • Marine Drugs, August 2012, MDPI AG

    Dr Chienchih Chiu

  112. Protective Effect of Caffeic Acid on Paclitaxel Induced Anti-Proliferation and Apoptosis of Lung Cancer Cells Involves NF-κB Pathway

    Article • International Journal of Molecular Sciences, May 2012, MDPI AG

    Dr Chienchih Chiu

  113. Biological Properties of Acidic Cosmetic Water from Seawater

    Article • International Journal of Molecular Sciences, May 2012, MDPI AG

    Dr Chienchih Chiu

  114. Anti-allergic activity of grapeseed extract (GSE) on RBL-2H3 mast cells

    Article • Food Chemistry, May 2012, Elsevier

    Dr Chienchih Chiu

  115. Bio-Functional Constituents from the Stems of Liriodendron tulipifera

    Article • Molecules, April 2012, MDPI AG

    Dr Chienchih Chiu

  116. Proteomic investigation of anti‐tumor activities exerted by sinularin against A2058 melanoma cells

    Article • Electrophoresis, April 2012, Wiley

    Dr Chienchih Chiu

  117. The Aqueous Extract of Prunella vulgaris Suppresses Cell Invasion and Migration in Human Liver Cancer Cells by Attenuating Matrix Metalloproteinases

    Article • The American Journal of Chinese Medicine, January 2012, World Scientific Pub Co Pte Lt

    Dr Chienchih Chiu

  118. Orai1/CRACM1 overexpression suppresses cell proliferation via attenuation of the store-operated calcium influx-mediated signalling pathway in A549 lung cancer cells

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, December 2011, Elsevier

    Dr Chienchih Chiu

  119. Characterization and enhancement of chondrogenesis in porous hyaluronic acid-modified scaffolds made of PLGA(75/25) blended with PEI-grafted PLGA(50/50)

    Article • Materials Science and Engineering C, October 2011, Elsevier

    Dr Chienchih Chiu

  120. Subamolide E from Cinnamomum subavenium Induces Sub-G1 Cell-Cycle Arrest and Caspase-Dependent Apoptosis and Reduces the Migration Ability of Human Melanoma Cells

    Article • Journal of Agricultural and Food Chemistry, July 2011, American Chemical Society (ACS)

    Dr Chienchih Chiu

  121. Overexpression of Rho GDP-dissociation inhibitor alpha predicts poor survival in oral squamous cell carcinoma

    Article • Oral Oncology, June 2011, Elsevier

    Dr Chienchih Chiu

  122. Goniothalamin Inhibits Growth of Human Lung Cancer Cells through DNA Damage, Apoptosis, and Reduced Migration Ability

    Article • Journal of Agricultural and Food Chemistry, March 2011, American Chemical Society (ACS)

    Dr Chienchih Chiu

  123. Antitumor Efficacy of Doxorubicin Released from Crosslinked Nanoparticulate Chondroitin Sulfate/Chitosan Polyelectrolyte Complexes

    Article • Macromolecular Bioscience, February 2011, Wiley

    Dr Chienchih Chiu

  124. San‐Huang‐Xie‐Xin‐Tang extract suppresses hepatitis C virus replication and virus‐induced cyclooxygenase‐2 expression

    Article • Journal of Viral Hepatitis, January 2011, Wiley

    Dr Chienchih Chiu

  125. Anticancer Activity of Released Doxorubicin from a Folate-Mediated Polyelectrolyte Complex

    Article • Journal of Biomaterials Science Polymer Edition, January 2011, Taylor & Francis

    Dr Chienchih Chiu

  126. CASP3 gene single-nucleotide polymorphism (rs72689236) and Kawasaki disease in Taiwanese children

    Article • Journal of Human Genetics, December 2010, Springer Science + Business Media

    Dr Chienchih Chiu

  127. Obtusilactone A and (−)-sesamin induce apoptosis in human lung cancer cells by inhibiting mitochondrial Lon protease and activating DNA damage checkpoints

    Article • Cancer Science, November 2010, Wiley

    Dr Chienchih Chiu

  128. Highly potent and specific siRNAs against E6 or E7 genes of HPV16- or HPV18-infected cervical cancers

    Article • Cancer Gene Therapy, October 2010, Springer Science + Business Media

    Dr Chienchih Chiu

  129. Additive effects of C2-ceramide on paclitaxel-induced premature senescence of human lung cancer cells

    Article • Life Sciences, September 2010, Elsevier

    Dr Chienchih Chiu

  130. p38 MAPK and NF-κB pathways are involved in naphtho[1,2-b] furan-4,5-dione induced anti-proliferation and apoptosis of human hepatoma cells

    Article • Cancer Letters, September 2010, Elsevier

    Dr Chienchih Chiu

  131. Taiwan cobra cardiotoxin III inhibits Src kinase leading to apoptosis and cell cycle arrest of oral squamous cell carcinoma Ca9-22 cells

    Article • Toxicon, September 2010, Elsevier

    Dr Chienchih Chiu

  132. Betel quid extract promotes oral cancer cell migration by activating a muscarinic M4 receptor-mediated signaling cascade involving SFKs and ERK1/2

    Article • Biochemical and Biophysical Research Communications, August 2010, Elsevier

    Dr Chienchih Chiu

  133. Decreased expression of thrombomodulin is correlated with tumor cell invasiveness and poor prognosis in nonsmall cell lung cancer

    Article • Molecular Carcinogenesis, July 2010, Wiley

    Professor Yung-Hsiang Chen, Dr Chienchih Chiu

  134. 4β-Hydroxywithanolide E from Physalis peruviana (golden berry) inhibits growth of human lung cancer cells through DNA damage, apoptosis and G2/M arrest

    Article • BMC Cancer, February 2010, Springer Science + Business Media

    Dr Chienchih Chiu

  135. Contributions of active site residues to cofactor binding and catalysis of 3α-hydroxysteroid dehydrogenase/carbonyl reductase

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, January 2010, Elsevier

    Dr Chienchih Chiu

  136. Fern Plant–Derived Protoapigenone Leads to DNA Damage, Apoptosis, and G 2 /M Arrest in Lung Cancer Cell Line H1299

    Article • DNA and Cell Biology, October 2009, Mary Ann Liebert Inc

    Dr Chienchih Chiu

  137. Serine protease inhibitor (SERPIN) B1 promotes oral cancer cell motility and is over-expressed in invasive oral squamous cell carcinoma

    Article • Oral Oncology, September 2009, Elsevier

    Dr Chienchih Chiu

  138. Effects of Cardiotoxin III on NF-κB Function, Proliferation, and Apoptosis in Human Breast MCF-7 Cancer Cells

    Article • Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics, January 2009, Computers, Materials and Continua (Tech Science Press)

    Dr Chienchih Chiu

  139. Cisplatin-Induced Senescence and Growth Inhibition in Human Non-Small Cell Lung Cancer Cells With Ectopic Transfer of <I>p16<SUP>I NK4a</SUP> </I>

    Article • Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics, October 2007, Computers, Materials and Continua (Tech Science Press)

    Dr Chienchih Chiu

  140. Etoposide (VP-16) elicits apoptosis following prolonged G2-M cell arrest in p53-mutated human non-small cell lung cancer cells

    Article • Cancer Letters, June 2005, Elsevier

    Dr Chienchih Chiu

  141. Etoposide (VP-16) sensitizes p53-deficient human non-small cell lung cancer cells to caspase-7-mediated apoptosis

    Article • APOPTOSIS, May 2005, Springer Science + Business Media

    Dr Chienchih Chiu

  142. The suppressed proliferation and premature senescence by ganciclovir in p53-mutated human non-small-lung cancer cells acquiring herpes simplex virus-thymidine kinase cDNA

    Article • Cancer Detection and Prevention, January 2005, Elsevier

    Dr Chienchih Chiu

  143. Ectopic expression of herpes simplex virus‐thymidine kinase gene in human non‐small cell lung cancer cells conferred caspase‐activated apoptosis sensitized by ganciclovir

    Article • International Journal of Cancer, September 2002, Wiley

    Dr Chienchih Chiu