All Stories

  1. Cerebral Malaria and Severe Malarial Anemia, but not Other Forms of Severe Malaria, Are Associated With Long-Term Cognitive Impairment

    Article • Clinical Infectious Diseases, February 2026, Oxford University Press (OUP)

    Dr Chandy C John

  2. Hydroxyurea pharmacokinetics in children with sickle cell anemia across different global populations

    Article • Blood Advances, January 2026, American Society of Hematology

    Dr Chandy C John

  3. Elevated Levels of PDGF-BB and VEGF Are Associated With a Decreased Risk of Readmission or Death in Children With Severe Malarial Anemia

    Article • The Journal of Infectious Diseases, October 2024, Oxford University Press (OUP)

    Dr Chandy C John

  4. Hydroxyurea reduces infections in children with sickle cell anemia in Uganda

    Article • Blood, April 2024, American Society of Hematology

    Dr Chandy C John

  5. Subclinical Inflammation in Asymptomatic Schoolchildren With Plasmodium falciparum Parasitemia Correlates With Impaired Cognition

    Article • Journal of the Pediatric Infectious Diseases Society, March 2024, Oxford University Press (OUP)

    Dr Chandy C John

  6. sTREM-1: A Biomarker of Mortality in Severe Malaria Impacted by Acute Kidney Injury

    Article • The Journal of Infectious Diseases, December 2023, Oxford University Press (OUP)

    Dr Chandy C John

  7. Effect of Malaria and Malaria Chemoprevention Regimens in Pregnancy and Childhood on Neurodevelopmental and Behavioral Outcomes in Children at 12, 24, and 36 Months: A Randomized Clinical Trial

    Article • Clinical Infectious Diseases, October 2022, Oxford University Press (OUP)

    Dr Chandy C John

  8. What Can Twins Teach Us About Malaria Epidemiology?

    Article • The Journal of Infectious Diseases, July 2022, Oxford University Press (OUP)

    Dr Chandy C John

  9. Impact of Oxidative Stress on Risk of Death and Readmission in African Children With Severe Malaria: A Prospective Observational Study

    Article • The Journal of Infectious Diseases, June 2022, Oxford University Press (OUP)

    Dr Chandy C John

  10. Decreased parasite burden and altered host response in children with sickle cell anemia and severe anemia with malaria

    Article • Blood Advances, November 2021, American Society of Hematology

    Dr Chandy C John

  11. Recommendations for Prevention and Control of Influenza in Children, 2021–2022

    Article • PEDIATRICS, October 2021, American Academy of Pediatrics (AAP)

    Dr Chandy C John

  12. The prevalence and density of asymptomatic Plasmodium falciparum infections among children and adults in three communities of western Kenya

    Article • Malaria Journal, September 2021, Springer Science + Business Media

    Dr Chandy C John

  13. Adults Are Not Big Children: What Brain Magnetic Resonance Imaging Findings Tell Us About Differences in Pediatric and Adult Cerebral Malaria

    Article • Clinical Infectious Diseases, December 2020, Oxford University Press (OUP)

    Dr Chandy C John

  14. Hydroxyurea Dose Escalation for Sickle Cell Anemia in Sub-Saharan Africa

    Article • The New England Journal of Medicine and Surgery and the Collateral Branches of Science, June 2020, New England Journal of Medicine (NEJM/MMS)

    Dr Chandy C John

  15. Brain Death Secondary to Rocky Mountain Spotted Fever Encephalitis

    Article • Case Reports in Critical Care, May 2020, Wiley

    Dr Chandy C John

  16. Zinc for Infection Prevention in Sickle Cell Anemia (ZIPS): study protocol for a randomized placebo-controlled trial in Ugandan children with sickle cell anemia

    Article • Trials, July 2019, Springer Science + Business Media

    Dr Chandy C John

  17. Zinc for Infection Prevention in Sickle Cell Anemia (ZIPS): Study Protocol for a Randomized Placebo-Controlled Trial in Ugandan children with Sickle Cell Anemia

    Article • July 2019, Springer Science + Business Media

    Dr Chandy C John

  18. Zinc for Infection Prevention in Sickle Cell Anemia (ZIPS): Study Protocol for a Randomized Placebo-Controlled Trial in Ugandan children with Sickle Cell Anemia

    Article • February 2019, Springer Science + Business Media

    Dr Chandy C John

  19. Novel use Of Hydroxyurea in an African Region with Malaria (NOHARM): a trial for children with sickle cell anemia

    Article • Blood, October 2017, American Society of Hematology

    Dr Chandy C John

  20. CSF TNF in cerebral malaria and cognitive impairment

    Article • Parasite Immunology, May 2017, Wiley

    Dr Chandy C John

  21. Differing Causes of Lactic Acidosis and Deep Breathing in Cerebral Malaria and Severe Malarial Anemia May Explain Differences in Acidosis-Related Mortality

    Article • PLOS One, September 2016, PLOS

    Dr Chandy C John

  22. Delaying Iron Therapy until 28 Days after Antimalarial Treatment Is Associated with Greater Iron Incorporation and Equivalent Hematologic Recovery after 56 Days in Children: A Randomized Controlled Trial

    Article • Journal of Nutrition, June 2016, American Society for Nutrition

    Dr Sarah E Cusick, Dr Chandy C John

  23. Novel Use of Hydroxyurea in an African Region With Malaria: Protocol for a Randomized Controlled Clinical Trial

    Article • JMIR Research Protocols, June 2016, JMIR Publications Inc.

    Dr Chandy C John

  24. Timing of iron and antimalarial treatment

    Article • American Journal of Clinical Nutrition, February 2016, American Society for Nutrition

    Dr Sarah E Cusick, Dr Chandy C John

  25. Effect of transmission intensity and age on subclass antibody responses to Plasmodium falciparum pre-erythrocytic and blood-stage antigens

    Article • Acta Tropica, February 2015, Elsevier

    Dr Chandy C John

  26. Micronutrient Deficiency and Immunity

    Article • July 2014, Taylor & Francis

    Dr Chandy C John

  27. Changes in Antigen-Specific Cytokine and Chemokine Responses to Plasmodium falciparum Antigens in a Highland Area of Kenya after a Prolonged Absence of Malaria Exposure

    Article • Infection and Immunity, June 2014, ASM Journals

    Dr Chandy C John

  28. Sensitivity of fever for diagnosis of clinical malaria in a Kenyan area of unstable, low malaria transmission

    Article • Malaria Journal, April 2014, Springer Science + Business Media

    Dr Chandy C John

  29. Use of a three-band HRP2/pLDH combination rapid diagnostic test increases diagnostic specificity for falciparum malaria in Ugandan children

    Article • Malaria Journal, February 2014, Springer Science + Business Media

    Dr Chandy C John

  30. Cerebral Malaria

    Article • January 2014, Springer Science + Business Media

    Dr Chandy C John

  31. Pediatric Infectious Diseases

    Article • Pediatric Clinics of North America, April 2013, Elsevier

    Dr Chandy C John

  32. Infections in Internationally Adopted Children

    Article • Pediatric Clinics of North America, April 2013, Elsevier

    Dr Chandy C John

  33. The Association between Cognition and Academic Performance in Ugandan Children Surviving Malaria with Neurological Involvement

    Article • PLOS One, February 2013, PLOS

    Dr Chandy C John

  34. Standardization and validation of a cytometric bead assay to assess antibodies to multiple Plasmodium falciparum recombinant antigens

    Article • Malaria Journal, December 2012, Springer Science + Business Media

    Dr Chandy C John

  35. Immunomodulation inPlasmodium falciparummalaria: experiments in nature and their conflicting implications for potential therapeutic agents

    Article • Expert Review of Anti-infective Therapy, November 2012, Taylor & Francis

    Dr Chandy C John

  36. Correction: Recurrent Plasmodium falciparum Malaria Infections in Kenyan Children Diminish T-Cell Immunity to Epstein Barr Virus Lytic but Not Latent Antigens

    Article • PLOS One, June 2012, PLOS

    Dr Chandy C John

  37. Faculty Opinions recommendation of Iron deficiency protects against severe Plasmodium falciparum malaria and death in young children.

    Article • March 2012, F1000Research

    Dr Chandy C John

  38. Faculty Opinions recommendation of Predicting the clinical outcome of severe falciparum malaria in african children: findings from a large randomized trial.

    Article • March 2012, F1000Research

    Dr Chandy C John

  39. Faculty Opinions recommendation of Voriconazole drug monitoring in the management of invasive fungal infection in immunocompromised children: a prospective study.

    Article • March 2012, F1000Research

    Dr Chandy C John

  40. Recurrent Plasmodium falciparum Malaria Infections in Kenyan Children Diminish T-Cell Immunity to Epstein Barr Virus Lytic but Not Latent Antigens

    Article • PLOS One, March 2012, PLOS

    Dr Chandy C John

  41. Faculty Opinions recommendation of Relation between falciparum malaria and bacteraemia in Kenyan children: a population-based, case-control study and a longitudinal study.

    Article • December 2011, F1000Research

    Dr Chandy C John

  42. Antibodies to Plasmodium falciparum Erythrocyte-binding Antigen-175 are Associated With Protection From Clinical Malaria

    Article • The Pediatric Infectious Disease Journal, December 2011, Wolters Kluwer Health

    Dr Chandy C John

  43. Malaria with neurological involvement in Ugandan children: effect on cognitive ability, academic achievement and behaviour

    Article • Malaria Journal, November 2011, Springer Science + Business Media

    Dr Chandy C John

  44. Diagnosing latent tuberculosis in international adoptees remains challenging

    Article • The Journal of Pediatrics, November 2011, Elsevier

    Dr Chandy C John

  45. Nitric oxide for the adjunctive treatment of severe malaria: Hypothesis and rationale

    Article • Medical Hypotheses, September 2011, Elsevier

    Dr Chandy C John

  46. Cognition, behaviour and academic skills after cognitive rehabilitation in Ugandan children surviving severe malaria: a randomised trial

    Article • BMC Neurology, August 2011, Springer Science + Business Media

    Dr Chandy C John

  47. Inhaled nitric oxide for the adjunctive therapy of severe malaria: Protocol for a randomized controlled trial

    Article • Trials, July 2011, Springer Science + Business Media

    Dr Chandy C John

  48. Development of a Competency-Based Curriculum in Global Child Health

    Article • Academic Medicine, April 2011, Oxford University Press (OUP)

    Dr Chandy C John

  49. Malaria (Plasmodium)

    Article • January 2011, Elsevier

    Dr Chandy C John

  50. Health Advice for Children Traveling Internationally

    Article • January 2011, Elsevier

    Dr Chandy C John

  51. Local topographic wetness indices predict household malaria risk better than land-use and land-cover in the western Kenya highlands

    Article • Malaria Journal, November 2010, Springer Science + Business Media

    Dr Chandy C John

  52. Cerebral Malaria: Mechanisms of Brain Injury and Strategies for Improved Neurocognitive Outcome

    Article • Pediatric Research, October 2010, Springer Science + Business Media

    Dr Chandy C John

  53. Adjunctive therapy for cerebral malaria and other severe forms ofPlasmodium falciparummalaria

    Article • Expert Review of Anti-infective Therapy, September 2010, Taylor & Francis

    Dr Chandy C John

  54. Primary Autoimmune Neutropenia Uncovered by Methicillin-Resistant Staphylococcus aureus Osteomyelitis

    Article • Infectious Diseases in Clinical Practice, July 2010, Wolters Kluwer Health

    Dr Chandy C John

  55. Reply to Landman and Groeneveld

    Article • Clinical Infectious Diseases, May 2010, Oxford University Press (OUP)

    Dr Chandy C John

  56. Staphylococcal Toxic Shock Syndrome Erythroderma Is Associated with Superantigenicity and Hypersensitivity

    Article • Clinical Infectious Diseases, December 2009, Oxford University Press (OUP)

    Dr Chandy C John

  57. Possible Interruption of Malaria Transmission, Highland Kenya, 2007–2008

    Article • Emerging Infectious Diseases, December 2009, Centers for Disease Control and Prevention (CDC)

    Dr Chandy C John

  58. Reliability of the Luganda version of the Child Behaviour Checklist in measuring behavioural problems after cerebral malaria

    Article • Child and Adolescent Psychiatry and Mental Health, December 2009, Springer Science + Business Media

    Dr Chandy C John

  59. Socioeconomic Predictors of Cognition in Ugandan Children: Implications for Community Interventions

    Article • PLOS One, November 2009, PLOS

    Dr Chandy C John

  60. Characterization of immunoglobulin G antibodies to Plasmodium falciparum sporozoite surface antigen MB2 in malaria exposed individuals

    Article • Malaria Journal, October 2009, Springer Science + Business Media

    Dr Chandy C John, Anthony James

  61. Environmental, socio‐demographic and behavioural determinants of malaria risk in the western Kenyan highlands: a case–control study

    Article • Tropical Medicine & International Health, September 2009, Wiley

    Dr Chandy C John

  62. Immediate Neuropsychological and Behavioral Benefits of Computerized Cognitive Rehabilitation in Ugandan Pediatric Cerebral Malaria Survivors

    Article • Journal of Developmental & Behavioral Pediatrics, August 2009, Wolters Kluwer Health

    Dr Chandy C John

  63. A Note to His Surgeon

    Article • JAMA, May 2009, American Medical Association (AMA)

    Dr Chandy C John

  64. Serum Angiopoietin-1 and -2 Levels Discriminate Cerebral Malaria from Uncomplicated Malaria and Predict Clinical Outcome in African Children

    Article • PLOS One, March 2009, PLOS

    Dr Chandy C John

  65. Malaria treatment-seeking behaviour and recovery from malaria in a highland area of Kenya

    Article • Malaria Journal, November 2008, Springer Science + Business Media

    Dr Chandy C John

  66. Inpatient Mortality in Children With Clinically Diagnosed Malaria As Compared With Microscopically Confirmed Malaria

    Article • The Pediatric Infectious Disease Journal, April 2008, Wolters Kluwer Health

    Dr Chandy C John

  67. Elevated serum levels of IL-1ra in children with Plasmodium falciparum malaria are associated with increased severity of disease

    Article • Cytokine, March 2008, Elsevier

    Dr Chandy C John

  68. Topography-derived wetness indices are associated with household-level malaria risk in two communities in the western Kenyan highlands

    Article • Malaria Journal, February 2008, Springer Science + Business Media

    Dr Chandy C John

  69. Antibodies to Pre‐erythrocytic Plasmodium falciparum Antigens and Risk of Clinical Malaria in Kenyan Children

    Article • The Journal of Infectious Diseases, February 2008, Oxford University Press (OUP)

    Dr Chandy C John, Dr Aaron Joseph Tande

  70. Cerebral Malaria Pathogenesis

    Article • American Journal Of Pathology, December 2007, Elsevier

    Dr Chandy C John

  71. Low Levels of RANTES Are Associated with Mortality in Children with Cerebral Malaria

    Article • The Journal of Infectious Diseases, September 2006, Oxford University Press (OUP)

    Dr Chandy C John

  72. Rehabilitation for cognitive impairments after cerebral malaria in African children: strategies and limitations

    Article • Tropical Medicine & International Health, August 2006, Wiley

    Dr Chandy C John

  73. Therapies and Vaccines for Emerging Bacterial Infections: Learning from Methicillin-resistant Staphylococcus aureus

    Article • Pediatric Clinics of North America, August 2006, Elsevier

    Dr Chandy C John

  74. Antibodies to Plasmodium falciparum Antigens Vary by Age and Antigen in Children in a Malaria-Holoendemic Area of Kenya

    Article • The Pediatric Infectious Disease Journal, August 2005, Wolters Kluwer Health

    Dr Chandy C John

  75. Risk of Plasmodium falciparum infection during a malaria epidemic in highland Kenya, 1997

    Article • Acta Tropica, September 2004, Elsevier

    Dr Chandy C John

  76. Drug treatment of malaria in children

    Article • The Pediatric Infectious Disease Journal, July 2003, Wolters Kluwer Health

    Dr Chandy C John

  77. The revolution in molecular biology leads to new understanding of the clinical expression of immunodeficiencies

    Article • The Journal of Pediatrics, February 2003, Elsevier

    Dr Chandy C John

  78. Recurrent fever in children

    Article • The Pediatric Infectious Disease Journal, November 2002, Wolters Kluwer Health

    Dr Chandy C John

  79. Community-Acquired, Non-Antibiotic-Associated Clostridium difficile Colitis in a Child

    Article • Infectious Diseases in Clinical Practice, September 2002, Wolters Kluwer Health

    Dr Chandy C John

  80. About your child

    Article • Journal of General Internal Medicine, October 1999, Springer Science + Business Media

    Dr Chandy C John

  81. SUCCESSFUL MEROPENEM TREATMENT OF MULTIPLY RESISTANT PNEUMOCOCCAL MENINGITIS

    Article • The Pediatric Infectious Disease Journal, October 1997, Wolters Kluwer Health

    Dr Chandy C John

  82. Flogging Trolls

    Article • Annals of Internal Medicine, February 1994, American College of Physicians

    Dr Chandy C John