All Stories

  1. IL-2 Complexed With Anti–IL-2 Antibody Expands the Maternal T-Regulatory Cell Pool and Alleviates Fetal Loss in Abortion-Prone Mice

    Article • American Journal Of Pathology, November 2024, Elsevier

    Dr. Carsten Merkwirth

  2. Mezagitamab in systemic lupus erythematosus: clinical and mechanistic findings of CD38 inhibition in an autoimmune disease

    Article • Lupus Science & Medicine, March 2024, BMJ

    Dr. Carsten Merkwirth

  3. Molecular characterization of type I IFN-induced cytotoxicity in bladder cancer cells reveals biomarkers of resistance

    Article • Molecular Therapy — Oncolytics, December 2021, Elsevier

    Dr. Carsten Merkwirth

  4. Aging review

    Article • Annual Review of Biochemistry, June 2016, Annual Reviews

    Dr. Carsten Merkwirth, Dr Celine E Riera

  5. Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria

    Article • Journal of Cell Biology, January 2016, Rockefeller University Press

    Dr. Carsten Merkwirth

  6. Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice

    Article • Science, December 2015, American Association for the Advancement of Science

    Dr. Carsten Merkwirth

  7. Inhibition of insulin/IGF-1 receptor signaling protects from mitochondria-mediated kidney failure

    Article • EMBO Molecular Medicine, February 2015, EMBO

    Dr. Carsten Merkwirth

  8. TRPV1 Pain Receptors Regulate Longevity and Metabolism by Neuropeptide Signaling

    Article • Cell, May 2014, Elsevier

    Professor Mark O. Huising, Dr. Carsten Merkwirth

  9. Loss of Prohibitin Induces Mitochondrial Damages Altering β-Cell Function and Survival and Is Responsible for Gradual Diabetes Development

    Article • Diabetes, September 2013, American Diabetes Association

    Dr. Carsten Merkwirth

  10. FOXO 4 is necessary for neural differentiation of human embryonic stem cells

    Article • Aging Cell, April 2013, Wiley

    Dr. Carsten Merkwirth

  11. Loss of Prohibitin Membrane Scaffolds Impairs Mitochondrial Architecture and Leads to Tau Hyperphosphorylation and Neurodegeneration

    Article • PLoS Genetics, November 2012, PLOS

    Dr. Carsten Merkwirth

  12. Increased proteasome activity in human embryonic stem cells is regulated by PSMD11

    Article • Nature, September 2012, Springer Science + Business Media

    Dr. Carsten Merkwirth

  13. RPN-6 determines C. elegans longevity under proteotoxic stress conditions

    Article • Nature, August 2012, Springer Science + Business Media

    Dr. Carsten Merkwirth

  14. The Mitochondrial Electron Transport Chain Is Dispensable for Proliferation and Differentiation of Epidermal Progenitor Cells

    Article • Stem Cells, August 2011, Oxford University Press (OUP)

    Dr. Carsten Merkwirth

  15. Obesity-induced overexpression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism

    Article • Nature Cell Biology, March 2011, Springer Science + Business Media

    Dr. Carsten Merkwirth

  16. Prohibitins and the functional compartmentalization of mitochondrial membranes

    Article • Journal of Cell Science, November 2009, The Company of Biologists

    Dr. Carsten Merkwirth

  17. SLP-2 is required for stress-induced mitochondrial hyperfusion

    Article • The EMBO Journal, April 2009, Springer Science + Business Media

    Dr. Carsten Merkwirth

  18. Prohibitin function within mitochondria: Essential roles for cell proliferation and cristae morphogenesis

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, January 2009, Elsevier

    Dr. Carsten Merkwirth

  19. Mitofusin 2 Builds a Bridge between ER and Mitochondria

    Article • Cell, December 2008, Elsevier

    Dr. Carsten Merkwirth

  20. Regulation of B cell homeostasis and activation by the tumor suppressor gene CYLD

    Article • Journal of Experimental Medicine, October 2007, Rockefeller University Press

    Dr. Carsten Merkwirth