All Stories

  1. A Computational Model for the Loss of Neuronal Organization in Microcolumns

    Article • Biophysical Journal, May 2014, Elsevier

    Professor Brigita Urbanc

  2. Minimal Model of Self-Assembly: Emergence of Diversity and Complexity

    Article • The Journal of Physical Chemistry B, March 2014, American Chemical Society (ACS)

    Professor Brigita Urbanc

  3. Assembly of Amyloid β-Protein Variants Containing Familial Alzheimer’s Disease-Linked Amino Acid Substitutions

    Article • January 2014, Elsevier

    Professor Brigita Urbanc

  4. Discrete Molecular Dynamics Study of Oligomer Formation by N-Terminally Truncated Amyloid β-Protein

    Article • Journal of Molecular Biology, June 2013, Elsevier

    Professor Brigita Urbanc

  5. pH-Independence of Trialanine and the Effects of Termini Blocking in Short Peptides: A Combined Vibrational, NMR, UVCD, and Molecular Dynamics Study

    Article • The Journal of Physical Chemistry B, March 2013, American Chemical Society (ACS)

    Professor Brigita Urbanc

  6. Insights into Aβ Aggregation: A Molecular Dynamics Perspective

    Article • Current Topics in Medicinal Chemistry, March 2013, Bentham Science Publishers

    Professor Brigita Urbanc

  7. Insights into Aβ Aggregation: A Molecular Dynamics Perspective

    Article • Current Topics in Medicinal Chemistry, March 2013, Bentham Science Publishers

    Professor Brigita Urbanc

  8. From Disordered Amyloid β-Proteins to Soluble Oligomers and Protofibrils Using Discrete Molecular Dynamics

    Article • January 2013, World Scientific Pub Co Pte Lt

    Professor Nikolay V Dokholyan, Professor Brigita Urbanc

  9. Discrete Molecular Dynamics Study of Oligomer Formation by N-Terminally Truncated Amyloid B-Protein

    Article • Biophysical Journal, January 2013, Elsevier

    Professor Brigita Urbanc

  10. The Role of Di-Tyrosine Bonding in Amyloid Beta-Protein Assembly

    Article • Biophysical Journal, January 2013, Elsevier

    Professor Brigita Urbanc

  11. Folding of pig gastric mucin non-glycosylated domains: a discrete molecular dynamics study

    Article • Journal of Biological Physics, September 2012, Springer Science + Business Media

    Professor Brigita Urbanc

  12. Dynamics of Metastable β-Hairpin Structures in the Folding Nucleus of Amyloid β-Protein

    Article • The Journal of Physical Chemistry B, May 2012, American Chemical Society (ACS)

    Professor Brigita Urbanc

  13. Dimer Formation Enhances Structural Differences between Amyloid β-Protein (1–40) and (1–42): An Explicit-Solvent Molecular Dynamics Study

    Article • PLoS ONE, April 2012, PLOS

    Professor Brigita Urbanc

  14. Computational Studies of Folding and Assembly of Amyloidogenic Proteins

    Article • February 2012, Wiley

    Professor Brigita Urbanc

  15. Is the Amino Acid Dipeptide a Suitable Model for Investigating Structural Preferences in the Unfolded State?

    Article • Biophysical Journal, January 2012, Elsevier

    Professor Brigita Urbanc

  16. Aβ42 oligomers, but not fibrils, simultaneously bind to and cause damage to ganglioside-containing lipid membranes

    Article • Biochemical Journal, October 2011, Portland Press Ltd.

    Professor Brigita Urbanc

  17. Structural Basis for Aβ1–42 Toxicity Inhibition by Aβ C-Terminal Fragments: Discrete Molecular Dynamics Study

    Article • Journal of Molecular Biology, July 2011, Elsevier

    Professor Brigita Urbanc

  18. Structural Basis for Amyloid β-Protein Toxicity Inhibition: A Multiscale Computational Study

    Article • Biophysical Journal, February 2011, Elsevier

    Professor Brigita Urbanc

  19. Minimalistic Approach to Protein Assembly Modelling/Application to the Sickle Cell Hemoglobin Polymerization

    Article • Biophysical Journal, February 2011, Elsevier

    Professor Brigita Urbanc

  20. Effects of the Arctic (E22→G) Mutation on Amyloid β-Protein Folding: Discrete Molecular Dynamics Study

    Article • Journal of the American Chemical Society, January 2011, American Chemical Society (ACS)

    Professor Brigita Urbanc

  21. Mechanistic Investigation of the Inhibition of Aβ42 Assembly and Neurotoxicity by Aβ42 C-Terminal Fragments

    Article • Biochemistry, July 2010, American Chemical Society (ACS)

    Professor Brigita Urbanc

  22. Elucidation of Amyloid β-Protein Oligomerization Mechanisms: Discrete Molecular Dynamics Study

    Article • Journal of the American Chemical Society, March 2010, American Chemical Society (ACS)

    Professor Brigita Urbanc

  23. Biophysical Characterization of Aβ42 C-Terminal Fragments: Inhibitors of Aβ42 Neurotoxicity

    Article • Biochemistry, January 2010, American Chemical Society (ACS)

    Professor Brigita Urbanc

  24. Computational Study of Assembly and Toxicity Inhibition of Amyloid Beta-Protein and Its Arctic Mutant

    Article • Biophysical Journal, February 2009, Elsevier

    Professor Brigita Urbanc

  25. Molecular Dynamics Simulations of a Single 11-Residue Beta-Sheet Adhesive and its Assembly

    Article • Biophysical Journal, February 2009, Elsevier

    Professor Brigita Urbanc

  26. Age-related reduction in microcolumnar structure correlates with cognitive decline in ventral but not dorsal area 46 of the rhesus monkey

    Article • Neuroscience, February 2009, Elsevier

    Professor Brigita Urbanc

  27. Effects of the Arctic (E22→G) Mutation on Amyloid β-Protein Folding: Discrete Molecular Dynamics Study

    Article • Journal of the American Chemical Society, December 2008, American Chemical Society (ACS)

    Professor Brigita Urbanc

  28. C-terminal peptides coassemble into Aβ42 oligomers and protect neurons against Aβ42-induced neurotoxicity

    Article • Proceedings of the National Academy of Sciences, September 2008, Proceedings of the National Academy of Sciences

    Professor Brigita Urbanc

  29. Automated identification of neurons and their locations

    Article • Journal of Microscopy, June 2008, Wiley

    Professor Brigita Urbanc

  30. Generating a model of the three-dimensional spatial distribution of neurons using density maps

    Article • NeuroImage, April 2008, Elsevier

    Professor Brigita Urbanc

  31. Role of Electrostatic Interactions in Amyloid β-Protein (Aβ) Oligomer Formation: A Discrete Molecular Dynamics Study

    Article • Biophysical Journal, June 2007, Elsevier

    Professor Brigita Urbanc

  32. Computer Simulations of Alzheimers Amyloid β-Protein Folding and Assembly

    Article • Current Alzheimer Research, December 2006, Bentham Science Publishers

    Professor Brigita Urbanc

  33. Elucidating Amyloid β-Protein Folding and Assembly:  A Multidisciplinary Approach

    Article • Accounts of Chemical Research, July 2006, American Chemical Society (ACS)

    Professor Brigita Urbanc

  34. Ab initio Discrete Molecular Dynamics Approach to Protein Folding and Aggregation

    Article • January 2006, Elsevier

    Professor Brigita Urbanc

  35. Solvent and mutation effects on the nucleation of amyloid β-protein folding

    Article • Proceedings of the National Academy of Sciences, December 2005, Proceedings of the National Academy of Sciences

    Professor Brigita Urbanc

  36. Possible Isostructural Transitions in the Ferroelectric Liquid Crystals in High External Electric Fields

    Article • Molecular Crystals and Liquid Crystals, June 2005, Taylor & Francis

    Professor Brigita Urbanc

  37. Folding events in the 21-30 region of amyloid β-protein (Aβ) studied in silico

    Article • Proceedings of the National Academy of Sciences, April 2005, Proceedings of the National Academy of Sciences

    Professor Brigita Urbanc

  38. A statistically based density map method for identification and quantification of regional differences in microcolumnarity in the monkey brain

    Article • Journal of Neuroscience Methods, February 2005, Elsevier

    Professor Brigita Urbanc

  39. In silico study of amyloid β-protein folding and oligomerization

    Article • Proceedings of the National Academy of Sciences, December 2004, Proceedings of the National Academy of Sciences

    Professor Brigita Urbanc

  40. Molecular Dynamics Simulation of Amyloid β Dimer Formation

    Article • Biophysical Journal, October 2004, Elsevier

    Professor Brigita Urbanc

  41. Discrete molecular dynamics simulations of peptide aggregation

    Article • Physical Review E, April 2004, American Physical Society (APS)

    Professor Brigita Urbanc

  42. Neuron recognition by parallel Potts segmentation

    Article • Proceedings of the National Academy of Sciences, March 2003, Proceedings of the National Academy of Sciences

    Professor Brigita Urbanc

  43. Neurotoxic effects of thioflavin S-positive amyloid deposits in transgenic mice and Alzheimer's disease

    Article • Proceedings of the National Academy of Sciences, October 2002, Proceedings of the National Academy of Sciences

    Professor Brigita Urbanc

  44. Plaque-induced neurite abnormalities in TG2576 HAPPSW over-expressing transgenic mice: Special role of thioflavine S plaques and implications for disruption of the neuropil

    Article • Neurobiology of Aging, May 2000, Elsevier

    Professor Brigita Urbanc

  45. Description of microcolumnar ensembles in association cortex and their disruption in Alzheimer and Lewy body dementias

    Article • Proceedings of the National Academy of Sciences, April 2000, Proceedings of the National Academy of Sciences

    Professor Brigita Urbanc

  46. Dynamic feedback in an aggregation-disaggregation model

    Article • August 1999, American Physical Society (APS)

    Professor Brigita Urbanc

  47. PLAQUE-INDUCED NEURITE ABNORMALITIES

    Article • Journal of Neuropathology & Experimental Neurology, May 1999, Oxford University Press (OUP)

    Professor Brigita Urbanc

  48. Plaque-induced neurite abnormalities: Implications for disruption of neural networks in Alzheimer’s disease

    Article • Proceedings of the National Academy of Sciences, April 1999, Proceedings of the National Academy of Sciences

    Professor Brigita Urbanc

  49. Dynamics of Plaque Formation in Alzheimer's Disease

    Article • Biophysical Journal, March 1999, Elsevier

    Professor Brigita Urbanc

  50. Statistical physics and Alzheimer’s disease

    Article • Physica A Statistical Mechanics and its Applications, January 1998, Elsevier

    Professor Brigita Urbanc

  51. Order parameter and segregated phases in a sandpile model with two particle sizes

    Article • August 1997, American Physical Society (APS)

    Professor Brigita Urbanc

  52. Aggregation and disaggregation of senile plaques in Alzheimer disease

    Article • Proceedings of the National Academy of Sciences, July 1997, Proceedings of the National Academy of Sciences

    Professor Brigita Urbanc

  53. Temporal correlations in a one-dimensional sandpile model

    Article • December 1996, American Physical Society (APS)

    Professor Brigita Urbanc

  54. Sandpile model on the Sierpinski gasket fractal

    Article • July 1996, American Physical Society (APS)

    Professor Brigita Urbanc

  55. Phase-excitation spectrum of ferroelectric liquid crystals in an external static electric field

    Article • October 1995, American Physical Society (APS)

    Professor Brigita Urbanc

  56. Microscopic origin of spontaneous polarization in ferroelectric SC∗ liquid crystals

    Article • Liquid Crystals, March 1995, Taylor & Francis

    Professor Brigita Urbanc

  57. Behavior of ferroelectric liquid crystals in external fields

    Article • February 1995, American Physical Society (APS)

    Professor Brigita Urbanc

  58. Theoretical investigation of the behavior of ferroelectric liquid crystals in a magnetic or in a high-frequency electric field

    Article • July 1993, American Physical Society (APS)

    Professor Brigita Urbanc

  59. Dielectric response of ferroelectric∗Cliquid crystals in a bias electric field

    Article • Liquid Crystals, July 1993, Taylor & Francis

    Professor Brigita Urbanc

  60. The influence of finite dimensions on the static ordering of the S*Cphase in an electric field

    Article • Liquid Crystals, January 1993, Taylor & Francis

    Professor Brigita Urbanc

  61. Nonlinear effects in the dielectric response of ferroelectric liquid crystals

    Article • Ferroelectrics, January 1991, Taylor & Francis

    Professor Brigita Urbanc

  62. The microscopic model of polar and quadrupolar ordering in ferroelectric smectic C*liquid crystals

    Article • Ferroelectrics, January 1991, Taylor & Francis

    Professor Brigita Urbanc

  63. Microscopic model of the spontaneous polarization in ferroelectric liquid crystals

    Article • Liquid Crystals, January 1989, Taylor & Francis

    Professor Brigita Urbanc

  64. Thermodynamic model of ferroelectric liquid crystals and its microscopic basis

    Article • Ferroelectrics, August 1988, Taylor & Francis

    Professor Brigita Urbanc

  65. Towards Inhibition of Amyloid β-protein Oligomerization

    Article • Springer Science + Business Media

    Professor Brigita Urbanc