All Stories

  1. A Review on the Synthesis and Anticancer Potentials of Imidazothiazole Derivatives
  2. Molecular Docking and In Vitro Anticancer Screening of Synthesized Arylthiazole linked 2H-indol-2-one Derivatives as VEGFR-2 Kinase Inhibitors
  3. Current Status of Novel Pyridine Fused Derivatives as Anticancer Agents: An Insight into Future Perspectives and Structure Activity Relationship (SAR)
  4. Coumarin linked heterocyclic hybrids: A promising approach to develop multi target drugs for Alzheimer's disease
  5. Synthesis, Molecular Docking, and Biological Evaluation of Some Novel 2-(5-Substituted 1,3,4-oxadiazole-2-yl)-1,3-benzothiazole Derivatives as Anticonvulsant Agents
  6. A Mini Review on Recent Advancements in the Therapeutic Potentials of Benzothiazoles
  7. APPROACHES FOR CHEMICAL SYNTHESIS AND DIVERSE PHARMACOLOGICAL SIGNIFICANCE OF PYRAZOLONE DERIVATIVES: A REVIEW
  8. Identification of metabolic pathways involved in the biotransformation of eslicarbazepine acetate using UPLC-MS/MS, human microsomal enzymes and in silico studies
  9. Recent advances in the development of chemotherapeutic agents for malaria.
  10. Synthesis, ADMET prediction and reverse screening study of 3,4,5-trimethoxy phenyl ring pendant sulfur‐containing cyanopyrimidine derivatives as promising apoptosis inducing anticancer agents
  11. Diverse Pharmacological Potential of Various Furanone Derivatives: A Mini-Review
  12. A review on synthetic procedures and applications of phosphorus oxychloride (POCl3) in the last biennial period (2018–19)
  13. Synthesis, in vitro cytotoxicity, ADME, and molecular docking studies of benzimidazole‐bearing furanone derivatives
  14. Design, synthesis, and biological evaluation of imidazopyridine‐linked thiazolidinone as potential anticancer agents
  15. SYNTHESIS AND SAR STRATEGY OF THIAZOLIDINEDIONE: A NOVEL APPROACH FOR CANCER TREATMENT
  16. A novel polyherbal formulation containing thymoquinone attenuates carbon tetrachloride-induced hepatorenal injury in a rat model
  17. Targeting malaria and leishmaniasis: Synthesis and pharmacological evaluation of novel pyrazole-1,3,4-oxadiazole hybrids. Part II
  18. Insights into the chemistry and therapeutic potential of furanones: A versatile pharmacophore
  19. Recent Advances towards Treatment of HIV: Synthesis and SAR Studies
  20. Synthesis, ADME, docking studies and in vivo anti-hyperglycaemic potential estimation of novel Schiff base derivatives from octadec-9-enoic acid
  21. Novel hybrids of benzothiazole-1,3,4-oxadiazole-4-thiazolidinone: Synthesis, in silico ADME study, molecular docking and in vivo anti-diabetic assessment
  22. Studies on new substituted pyridazinones: synthesis and biological evaluation
  23. Newly Synthesized Oxadiazole Based Mannich Base Derivatives of Fatty Acid: in Silico Study and in Vivo Anti-Hyperglycaemic Estimation
  24. A comprehensive review on Brigatinib – A wonder drug for targeted cancer therapy in non-small cell lung cancer
  25. Synthesis, molecular docking with COX 1& II enzyme, ADMET screening and in vivo anti-inflammatory activity of oxadiazole, thiadiazole and triazole analogs of felbinac
  26. Synthesis, molecular modelling studies and ADME prediction of benzothiazole clubbed oxadiazole-Mannich bases, and evaluation of their anti-diabetic activity through in vivo model
  27. Development of a stress induced validated UPLC-PDA method for the analysis of Eslicarbazepine acetate
  28. Nalidixic Acid Schiff Bases: Synthesis and Biological Evaluation
  29. Ameliorative effect of camel's milk and Nigella Sativa Oil against thioacetamide-induced hepatorenal damage in rats
  30. PI3K signaling pathway targeting by using different molecular approaches to treat cancer
  31. Chemical modification of acetaminophen: PASS assistedin vivo anti-inflammatory activity of chalcones, flavanones and Schiff bases
  32. Phenothiazines and Related Drugs as Multi Drug Resistance Reversal Agents in Cancer Chemotherapy Mediated by p-glycoprotein
  33. Oxidative Cyclization of Isoniazid with Fluoroquinolones: Synthesis, Antibacterial and Antitubercular Activity of New 2,5-disubstituted-1,3,4-Oxadiazoles
  34. Phytochemistry and potential therapeutic actions of Boswellic acids: A mini-review
  35. Design, synthesis and cytotoxic evaluation of novel imidazolone fused quinazolinone derivatives
  36. Novel 2,4-dichlorophenoxy acetic acid substituted thiazolidin-4-ones as anti-inflammatory agents: Design, synthesis and biological screening
  37. Forced Degradation Studies
  38. Quinoline based furanones and their nitrogen analogues: Docking, synthesis and biological evaluation
  39. Rational Design and Synthesis of Biologically Active Disubstituted 2(3H) Furanones and Pyrrolone Derivatives as Potent and Safer Non Steroidal Anti-inflammatory Agents
  40. Synthesis, antimicrobial and antitubercular activities of some novel pyrazoline derivatives
  41. Synthesis, Molecular Docking and Potential Antioxidant Activity of Di/Trisubstituted Pyridazinone Derivatives
  42. Synthesis, Biological Evaluation and Pharmacokinetic Studies of Mefenamic Acid - N-Hydroxymethylsuccinimide Ester Prodrug as Safer NSAID
  43. Synthesis and biological evaluation of a mutual prodrug of norfloxacin and fenbufen
  44. A review on dronedarone: Pharmacological, pharmacodynamic and pharmacokinetic profile
  45. Synthesis and in vivo diuretic activity of some new benzothiazole sulfonamides containing quinoxaline ring system
  46. Molecular modeling and synthesis of some new 2-imino-4-thiazolidinone derivatives with promising TNF-α inhibitory activity
  47. Synthesis, molecular properties, toxicity and biological evaluation of some new substituted imidazolidine derivatives in search of potent anti-inflammatory agents
  48. Design and synthesis of benzimidazoles containing substituted oxadiazole, thiadiazole and triazolo-thiadiazines as a source of new anticancer agents
  49. Design and synthesis of butenolide-based amide derivatives as anti-inflammatory agents
  50. Synthesis and biological evaluation of new hydrazide-Schiff bases
  51. Design, synthesis, molecular properties and antimicrobial activities of some novel 2(3H) pyrrolone derivatives
  52. Design and Synthesis of Butenolide-based Novel Benzyl Pyrrolones: Their TNF-αbased Molecular Docking withIn vivoandIn vitroAnti-inflammatory Activity
  53. Design, synthesis and biological evaluation of piperic acid triazolyl derivatives as potent anti-inflammatory agents
  54. Quantification of total phenol, flavonoid content and pharmacognostical evaluation including HPTLC fingerprinting for the standardization of Piper nigrum Linn fruits
  55. Structure Assessment Analysis of Core Domain of Seven Protein Data Bank Entries of HIV-1 Protease Using Different in-silico Techniques
  56. Attenuation of inflammatory mediators, oxidative stress and toxic risk evaluation of Aporosa lindleyana Baill bark extract
  57. Design and synthesis of pyrimidine molecules endowed with thiazolidin-4-one as new anticancer agents
  58. Anticancer Activity of New Compounds Using Benzimidazole as a Scaffold
  59. Essential aminoacid incorporated GABA–phthalimide derivatives: synthesis and anticonvulsant evaluation
  60. Synthesis, characterization, in vitro antimicrobial, and anthelmintic evaluations of 2-(4-chloro-3-methylphenoxy)-N′-[{5′-(substituted aryl)-furan-2′-yl}-methylidene]-acetohydrazides
  61. Application of LC–MS/MS for quantitative analysis of glucocorticoids and stimulants in biological fluids
  62. Synthesis, biological activities, and pharmacokinetics studies of a mutual prodrug of aceclofenac and paracetamol
  63. Anticonvulsant and Antitubercular Activities of 6-Phenyl/Biphenyl-4-yl-2- [2-(pyridin-2-ylamino)-ethyl]- and 6-(Biphenyl-4yl)-2-(2N-subtituted amin- 1-yl)-ethyl derivatives of 4,5-dihydropyridazin-3(2H)-one
  64. Analytical methods for the detection of undeclared synthetic drugs in traditional herbal medicines as adulterants
  65. A review on therapeutic potential of Nigella sativa: A miracle herb
  66. Synthesis and Biological Evaluation of Novel Substituted-Imidazolidine Derivatives
  67. Benzimidazole clubbed with triazolo-thiadiazoles and triazolo-thiadiazines: New anticancer agents
  68. Docking studies on butenolide derivatives as Cox-II inhibitors
  69. Synthesis and biological evaluation of di- and tri-substituted imidazoles as safer anti-inflammatory-antifungal agents
  70. Benzimidazole bearing oxadiazole and triazolo-thiadiazoles nucleus: Design and synthesis as anticancer agents
  71. Pharmacophore modeling studies on N-hydroxyphenyl acrylamides and N-hydroxypyridin-2-yl-acrylamides as inhibitor of human cancer leukemia K562 cells
  72. Synthesis of benzimidazoles bearing oxadiazole nucleus as anticancer agents
  73. 1-(1H-Benzimidazol-2-yl)-3-[5-(trichloromethyl)-1,3,4-oxadiazol-2-yl]propan-1-one
  74. Synthesis and antimicrobial activity of bischalcone derivatives
  75. Quinolone derivatives as antitubercular drugs
  76. Design, synthesis and antihypertensive screening of novel pyridazine substituted s-triazin-2-imine/one/thione derivatives
  77. Microbiological evaluation of 4-substituted-imidazolidine derivatives
  78. SYNTHESIS, CHARACTERIZATION AND ANTIHYPERTENSIVE ACTIVITY OF SOME NEW SUBSTITUTED PYRIDAZINE DERIVATIVES
  79. Heterocyclic compounds as carbonic anhydrase inhibitor
  80. 7-Phenyl-3,4,8,9-tetrahydro-2H-pyridazino[1,6-a][1,3,5]triazin-2-imine
  81. Triazole incorporated pyridazinones as a new class of antihypertensive agents: Design, synthesis and in vivo screening
  82. Synthesis and biological evaluation of some new pyridazinone derivatives
  83. Synthesis of quinoline attached-furan-2(3H)-ones having anti-inflammatory and antibacterial properties with reduced gastro-intestinal toxicity and lipid peroxidation
  84. Synthesis, antiinflammatory and antimicrobial activity of some new 1-(3-Phenyl-3,4-Dihydro-2H-1,3-Benzoxazin-6-yl)-ethanone derivatives
  85. SYNTHESIS AND ANTITUBERCULAR ACTIVITY OF PYRIDAZINONE DERIVATIVES
  86. 6-Phenyl-2-(4-phenyl-5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)-4,5-dihydropyridazin-3(2H)-one
  87. NEW AMIDES OF SULPHONAMIDES: SYNTHESIS AND BIOLOGICAL EVALUATION
  88. SYNTHESIS AND MICROBIOLOGICAL EVALUATION OF MANNICH BASES DERIVED FROM 4,6-DIACETYLRESORCINOL
  89. Studies on fused heterocyclic 3,6-disubstituted-1,2,4-triazolo-1,3,4-thiadiazoles: synthesis and biological evaluation
  90. Antimicrobial activities of some synthetic butenolides and their pyrrolone derivatives
  91. Synthesis of 6-aminomethyl derivatives of benzopyran-4-one with dual biological properties: Anti-inflammatory-analgesic and antimicrobial
  92. 3-Arylidene-5-(4-isobutylphenyl)-2(3H)-furanones: a new series of anti-inflammatory and analgesic compounds having antimicrobial activity
  93. Fenbufen based 3-[5-(substituted aryl)-1,3,4-oxadiazol-2-yl]-1-(biphenyl-4-yl)propan-1-ones as safer antiinflammatory and analgesic agents
  94. Synthesis and pharmacological evaluation of 2(3H)-furanones and 2(3H)-pyrrolones, combining analgesic and anti-inflammatory properties with reduced gastrointestinal toxicity and lipid peroxidation
  95. Aroylpropionic acid based 2,5-disubstituted-1,3,4-oxadiazoles: Synthesis and their anti-inflammatory and analgesic activities
  96. Synthesis and evaluation of in vitro antiviral activity of 2-[3-(substituted phenyl)-4,5-dihydro-1H-5-pyrazolyl]benzofuran-3-yl chloride derivatives
  97. Synthesis of novel 1,3,4-oxadiazole derivatives and their biological properties
  98. Synthesis and biological evaluation of β -aroylpropionic acid based 1,3,4-oxadiazoles
  99. Synthesis, reactions and biological activity of 3-arylidene-5-(4-methylphenyl)-2(3H)-furanones?
  100. Synthesis of 1-(4-phenoxyphenyl)-3-[5-(substituted aryl)-1,3,4-oxadiazol-2-yl]propan-1-ones as safer anti-inflammatory and analgesic agents
  101. Antibacterial and antifungal activities of 2-arylidene-4-(4-methylphenyl)but-3-en-4-olides and their pyrrolone derivatives
  102. 2-Arylidene-4-(4-phenoxy-phenyl)but-3-en-4-olides: Synthesis, reactions and biological activity
  103. SYNTHESIS AND ANTIBACTERIAL EVALUATION OF NEW FLAVONOID DERIVATIVES FROM 4,6-DIACETYL RESORCINOL
  104. SYNTHESIS OF SOME NEW PRODRUGS OF SULPHONAMIDES AND STUDIES ON THEIR ANTIMICROBIAL AND ANTI-INFLAMMATORY ACTION