All Stories

  1. Structure of the full‐length insecticidal protein Cry1Ac reveals intriguing details of toxin packaging into in vivo formed crystals

    Article • Protein Science, September 2014, Wiley

    Dr Artem Evdokimov

  2. Small-molecule phosphodiesterase probes: discovery of potent and selective CNS-penetrable quinazoline inhibitors of PDE1

    Article • MedChemComm, January 2014, Royal Society of Chemistry

    Dr Artem Evdokimov

  3. The Enzymology of alanine aminotransferase (AlaAT) isoforms from Hordeum vulgare and other organisms, and the HvAlaAT crystal structure

    Article • Archives of Biochemistry and Biophysics, December 2012, Elsevier

    Dr Artem Evdokimov

  4. Role of Unusual P Loop Ejection and Autophosphorylation in HipA-Mediated Persistence and Multidrug Tolerance

    Article • Cell Reports, September 2012, Elsevier

    Dr Artem Evdokimov

  5. Discovery of Brain-Penetrant, Irreversible Kynurenine Aminotransferase II Inhibitors for Schizophrenia

    Article • ACS Medicinal Chemistry Letters, March 2012, American Chemical Society (ACS)

    Dr Artem Evdokimov

  6. New kinase regulation mechanism found in HipBA: a bacterial persistence switch

    Article • Acta Crystallographica Section D Biological Crystallography, July 2009, International Union of Crystallography

    Dr Artem Evdokimov

  7. Crystal structure of the Yersinia pestis GTPase activator YopE

    Article • Protein Science, April 2009, Wiley

    Dr Artem Evdokimov, Dr David S Waugh

  8. Structural evidence for substrate-induced synergism and half-sites reactivity in biotin carboxylase

    Article • Protein Science, October 2008, Wiley

    Charles Kendall Stover, Dr Artem Evdokimov

  9. Corrigendum to “Design and synthesis of potent, non-peptidic inhibitors of HPTPβ” [Bioorg. Med. Chem. Lett. 16 (2006) 4252–4256]

    Article • Bioorganic & Medicinal Chemistry Letters, August 2008, Elsevier

    Dr Artem Evdokimov

  10. Farnesyl pyrophosphate synthase enantiospecificity with a chiral risedronate analog, [6,7-dihydro-5H-cyclopenta[c]pyridin-7-yl(hydroxy)methylene]bis(phosphonic acid) (NE-10501): Synthetic, structural, and modeling studies

    Article • Bioorganic & Medicinal Chemistry Letters, May 2008, Elsevier

    Dr Artem Evdokimov

  11. Rational protein engineering in action: The first crystal structure of a phenylalanine tRNA synthetase from Staphylococcus haemolyticus

    Article • Journal of Structural Biology, April 2008, Elsevier

    Professor Barry C Finzel, Dr Artem Evdokimov

  12. The interaction of sidechain nitrogen with active site threonine is not essential for inhibition of farnesyl pyrophosphate synthase by nitrogen containing bisphosphonates

    Article • Bone, March 2008, Elsevier

    Dr Artem Evdokimov

  13. Structural biology approaches to antibacterial drug discovery

    Article • Expert Opinion on Drug Discovery, August 2007, Informa Healthcare

    Dr Artem Evdokimov

  14. The development of 2-benzimidazole substituted pyrimidine based inhibitors of lymphocyte specific kinase (Lck)

    Article • Bioorganic & Medicinal Chemistry Letters, December 2006, Elsevier

    Dr Artem Evdokimov

  15. Engineering the catalytic domain of human protein tyrosine phosphatase β for structure-based drug discovery

    Article • Acta Crystallographica Section D Biological Crystallography, November 2006, International Union of Crystallography

    Dr Artem Evdokimov

  16. Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors

    Article • Proteins Structure Function and Bioinformatics, November 2006, Wiley

    Dr Artem Evdokimov

  17. Design and synthesis of substituted pyridine derivatives as HIF-1α prolyl hydroxylase inhibitors

    Article • Bioorganic & Medicinal Chemistry Letters, November 2006, Elsevier

    Dr Artem Evdokimov

  18. Design and synthesis of a series of novel pyrazolopyridines as HIF 1-α prolyl hydroxylase inhibitors

    Article • Bioorganic & Medicinal Chemistry Letters, November 2006, Elsevier

    Dr Artem Evdokimov

  19. Structure-based design, synthesis, and SAR evaluation of a new series of 8-hydroxyquinolines as HIF-1α prolyl hydroxylase inhibitors

    Article • Bioorganic & Medicinal Chemistry Letters, November 2006, Elsevier

    Dr Artem Evdokimov

  20. A novel series of imidazo[1,2-a]pyridine derivatives as HIF-1α prolyl hydroxylase inhibitors

    Article • Bioorganic & Medicinal Chemistry Letters, November 2006, Elsevier

    Dr Artem Evdokimov

  21. Design and synthesis of novel N-sulfonyl-2-indole carboxamides as potent PPAR-γ binding agents with potential application to the treatment of osteoporosis

    Article • Bioorganic & Medicinal Chemistry Letters, November 2006, Elsevier

    Dr Artem Evdokimov

  22. Structural basis for the fast maturation of Arthropoda green fluorescent protein

    Article • EMBO Reports, August 2006, EMBO

    Dr Artem Evdokimov

  23. MALDI-TOF MS as a label-free approach to rapid inhibitor screening

    Article • Journal of the American Society for Mass Spectrometry, June 2006, American Chemical Society (ACS)

    Dr Artem Evdokimov

  24. 1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors

    Article • Bioorganic & Medicinal Chemistry Letters, March 2006, Elsevier

    Dr Artem Evdokimov

  25. The Structure of Yersinia pestis V-Antigen, an Essential Virulence Factor and Mediator of Immunity against Plague

    Article • Structure, February 2004, Elsevier

    Dr Artem Evdokimov

  26. Similar modes of polypeptide recognition by export chaperones in flagellar biosynthesis and type III secretion

    Article • Nature Structural & Molecular Biology, September 2003, Springer Science + Business Media

    Dr Artem Evdokimov

  27. Mechanism of insulin sensitization by BMOV (bis maltolato oxo vanadium); unliganded vanadium (VO4) as the active component

    Article • Journal of Inorganic Biochemistry, August 2003, Elsevier

    Dr Artem Evdokimov

  28. Differential effects of short affinity tags on the crystallization ofPyrococcus furiosusmaltodextrin-binding protein

    Article • Acta Crystallographica Section D Biological Crystallography, February 2002, International Union of Crystallography

    Dr Artem Evdokimov

  29. Three-dimensional structure of the type III secretion chaperone SycE fromYersinia pestis

    Article • Acta Crystallographica Section D Biological Crystallography, February 2002, International Union of Crystallography

    Dr Artem Evdokimov

  30. Unusual molecular architecture of the Yersinia pestis cytotoxin YopM: a leucine-rich repeat protein with the shortest repeating unit 1 1Edited by R. Huber

    Article • Journal of Molecular Biology, September 2001, Elsevier

    Dr Artem Evdokimov

  31. Structure of the N-terminal domain ofYersinia pestisYopH at 2.0 Å resolution

    Article • Acta Crystallographica Section D Biological Crystallography, May 2001, International Union of Crystallography

    Dr Artem Evdokimov

  32. Structures of furanosides: geometrical analysis of low-temperature X-ray and neutron crystal structures of five crystalline methyl pentofuranosides

    Article • Acta Crystallographica Section B Structural Science, April 2001, International Union of Crystallography

    Felix Frolow, Dr Artem Evdokimov

  33. Structural basis for oligosaccharide recognition by Pyrococcus furiosus maltodextrin-binding protein

    Article • Journal of Molecular Biology, January 2001, Elsevier

    Dr Artem Evdokimov, Dr David S Waugh

  34. Overproduction, purification, crystallization and preliminary X-ray diffraction analysis of YopM, an essential virulence factor extruded by the plague bacteriumYersinia pestis

    Article • Acta Crystallographica Section D Biological Crystallography, December 2000, International Union of Crystallography

    Dr Artem Evdokimov

  35. Structures of Furanosides:  A Study of the Conformational Space of Methyl α- d -Lyxofuranoside by Density Functional Methods

    Article • The Journal of Physical Chemistry A, June 2000, American Chemical Society (ACS)

    Dr Artem Evdokimov

  36. Anti-Human Immunodeficiency Virus Activity of Novel Aminoglycoside-Arginine Conjugates at Early Stages of Infection

    Article • AIDS Research and Human Retroviruses, May 2000, Mary Ann Liebert Inc

    Dr Artem Evdokimov

  37. Aminoglycoside−Arginine Conjugates That Bind TAR RNA:  Synthesis, Characterization, and Antiviral Activity †

    Article • Biochemistry, March 2000, American Chemical Society (ACS)

    Dr Artem Evdokimov

  38. Arginine-aminoglycoside conjugates that bind to HIV transactivation responsive element RNA in vitro

    Article • FEBS Letters, February 1999, Wiley

    Dr Artem Evdokimov

  39. Structures of Furanosides:  Density Functional Calculations and High-Resolution X-ray and Neutron Diffraction Crystal Structures

    Article • The Journal of Physical Chemistry A, February 1999, American Chemical Society (ACS)

    Dr Artem Evdokimov