All Stories

  1. Microtubule detyrosination drives symmetry breaking to polarize cells for directed cell migration

    Article • Proceedings of the National Academy of Sciences, May 2023, Proceedings of the National Academy of Sciences

    Andrew B Goryachev

  2. A versatile cortical pattern-forming circuit based on Rho, F-actin, Ect2, and RGA-3/4

    Article • The Journal of Cell Biology, June 2022, Rockefeller University Press

    Andrew B Goryachev

  3. A versatile pattern-forming cortical circuit based on Rho, F-actin, Ect2, and RGA-3/4

    Article • March 2022, Cold Spring Harbor Laboratory Press

    Andrew B Goryachev

  4. Mechanosensitive calcium flashes promote sustained RhoA activation during tight junction remodeling

    Article • The Journal of Cell Biology, March 2022, Rockefeller University Press

    Andrew B Goryachev

  5. Cell cycle and developmental control of cortical excitability in Xenopus laevis

    Article • February 2022, Cold Spring Harbor Laboratory Press

    Andrew B Goryachev

  6. Rho and F-actin self-organize within an artificial cell cortex

    Article • Current Biology, December 2021, Elsevier

    Andrew B Goryachev

  7. Mechanosensitive calcium signaling in response to cell shape changes promotes epithelial tight junction remodeling by activating RhoA

    Article • May 2021, Cold Spring Harbor Laboratory Press

    Andrew B Goryachev

  8. Rho and F-actin self-organize within an artificial cell cortex

    Article • April 2021, Cold Spring Harbor Laboratory Press

    Andrew B Goryachev

  9. Type V myosin focuses the polarisome and shapes the tip of yeast cells

    Article • The Journal of Cell Biology, March 2021, Rockefeller University Press

    Andrew B Goryachev

  10. Symmetry Breaking as an Interdisciplinary Concept Unifying Cell and Developmental Biology

    Article • Cells, January 2021, MDPI AG

    Andrew B Goryachev

  11. Compete or Coexist? Why the Same Mechanisms of Symmetry Breaking Can Yield Distinct Outcomes

    Article • Cells, September 2020, MDPI AG

    Andrew B Goryachev

  12. Type V Myosin focuses the polarisome and shapes the tip of yeast cells

    Article • July 2020, Cold Spring Harbor Laboratory Press

    Andrew B Goryachev

  13. Cortical contraction drives the 3D patterning of epithelial cell surfaces

    Article • The Journal of Cell Biology, January 2020, Rockefeller University Press

    Andrew B Goryachev

  14. Pattern formation in active model C with anchoring: bands, aster networks, and foams

    Article • Soft Matter, January 2020, Royal Society of Chemistry

    Andrew B Goryachev

  15. Autoactivation of small GTPases by the GEF–effector positive feedback modules

    Article • F1000Research, September 2019, Faculty of 1000, Ltd.

    Andrew B Goryachev

  16. Spindle–F-actin interactions in mitotic spindles in an intact vertebrate epithelium

    Article • Molecular Biology of the Cell, July 2019, American Society for Cell Biology (ASCB)

    Andrew B Goryachev

  17. Fission Yeast NDR/LATS Kinase Orb6 Regulates Exocytosis via Phosphorylation of the Exocyst Complex

    Article • Cell Reports, February 2019, Elsevier

    Andrew B Goryachev

  18. Rho Flares Repair Local Tight Junction Leaks

    Article • Developmental Cell, February 2019, Elsevier

    Andrew B Goryachev

  19. Dry active turbulence in a model for microtubule–motor mixtures

    Article • Soft Matter, January 2019, Royal Society of Chemistry

    Andrew B Goryachev

  20. Autoamplification and Competition Drive Symmetry Breaking: Initiation of Centriole Duplication by the PLK4-STIL Network

    Article • iScience, October 2018, Elsevier

    Andrew B Goryachev

  21. Local and global Cdc42 guanine nucleotide exchange factors for fission yeast cell polarity are coordinated by microtubules and the Tea1–Tea4–Pom1 axis

    Article • Journal of Cell Science, June 2018, The Company of Biologists

    Andrew B Goryachev

  22. Fission yeast NDR/LATS kinase Orb6 regulates exocytosis via phosphorylation of exocyst complex

    Article • March 2018, Cold Spring Harbor Laboratory Press

    Andrew B Goryachev

  23. Kinetic theory of pattern formation in mixtures of microtubules and molecular motors

    Article • February 2018, American Physical Society (APS)

    Andrew B Goryachev

  24. Local and global Cdc42 GEFs for fission yeast cell polarity are coordinated by microtubules and the Tea1/Tea4/Pom1 axis

    Article • October 2017, Cold Spring Harbor Laboratory Press

    Andrew B Goryachev

  25. Cell Polarity: Spot-On Cdc42 Polarization Achieved on Demand

    Article • Current Biology, August 2017, Elsevier

    Andrew B Goryachev

  26. Gradient Sensing: Engineering the Yeast Love Affair

    Article • Current Biology, June 2016, Elsevier

    Andrew B Goryachev

  27. How to make a static cytokinetic furrow out of traveling excitable waves

    Article • Small GTPases, April 2016, Taylor & Francis

    Andrew B Goryachev

  28. Curvature-driven positioning of Turing patterns in phase-separating curved membranes

    Article • Soft Matter, January 2016, Royal Society of Chemistry

    Andrew B Goryachev

  29. Activator–inhibitor coupling between Rho signalling and actin assembly makes the cell cortex an excitable medium

    Article • Nature, October 2015, Nature

    Andrew B Goryachev

  30. Anillin Regulates Cell-Cell Junction Integrity by Organizing Junctional Accumulation of Rho-GTP and Actomyosin

    Article • Current Biology, June 2014, Elsevier

    Andrew B Goryachev

  31. CDC-42 and RAC-1 regulate opposite chemotropisms in Neurospora crassa

    Article • Journal of Cell Science, April 2014, The Company of Biologists

    Andrew B Goryachev

  32. Modelling the effect of myosin X motors on filopodia growth

    Article • Physical Biology, January 2014, Institute of Physics Publishing

    Andrew B Goryachev

  33. Highlight: The 5th International Workshop on Septin Biology

    Article • Biological Chemistry, January 2014, De Gruyter

    Andrew B Goryachev

  34. Daughter Cell Identity Emerges from the Interplay of Cdc42, Septins, and Exocytosis

    Article • Developmental Cell, July 2013, Elsevier

    Andrew B Goryachev

  35. Domain formation on curved membranes: phase separation or Turing patterns?

    Article • Soft Matter, January 2013, Royal Society of Chemistry

    Andrew B Goryachev

  36. The mechanistic basis of self-fusion between conidial anastomosis tubes during fungal colony initiation

    Article • Fungal Biology Reviews, April 2012, Elsevier

    Andrew B Goryachev

  37. Excitable behavior can explain the “ping-pong” mode of communication between cells using the same chemoattractant

    Article • BioEssays, January 2012, Wiley

    Andrew B Goryachev

  38. Lateral dynamics of charged lipids and peripheral proteins in spatially heterogeneous membranes: Comparison of continuous and Monte Carlo approaches

    Article • The Journal of Chemical Physics, October 2011, American Institute of Physics

    Andrew B Goryachev

  39. A common mechanism for protein cluster formation

    Article • Small GTPases, May 2011, Taylor & Francis

    Andrew B Goryachev

  40. System analysis shows distinct mechanisms and common principles of nuclear envelope protein dynamics

    Article • The Journal of Cell Biology, March 2011, Rockefeller University Press

    Dr Alastair R.W. Kerr, Andrew B Goryachev

  41. Lateral Dynamics of Proteins with Polybasic Domain on Anionic Membranes: A Dynamic Monte-Carlo Study

    Article • Biophysical Journal, March 2011, Elsevier

    Andrew B Goryachev

  42. Understanding Bacterial Cell−Cell Communication with Computational Modeling

    Article • Chemical Reviews, January 2011, American Chemical Society (ACS)

    Andrew B Goryachev

  43. A Catalytic Role for Mod5 in the Formation of the Tea1 Cell Polarity Landmark

    Article • Current Biology, October 2010, Elsevier

    Andrew B Goryachev

  44. Cellular deformation and intracellular stress propagation during optical stretching

    Article • Physical Review E, May 2010, American Physical Society (APS)

    Dr Soo Kng Teo, Andrew B Goryachev

  45. Self-signalling and self-fusion in filamentous fungi

    Article • Current Opinion in Microbiology, December 2009, Elsevier

    Andrew B Goryachev

  46. Singularity in Polarization: Rewiring Yeast Cells to Make Two Buds

    Article • Cell, November 2009, Elsevier

    Andrew B Goryachev

  47. Design principles of the bacterial quorum sensing gene networks

    Article • WIREs Systems Biology and Medicine, May 2009, Wiley

    Andrew B Goryachev

  48. p190RhoGAP is the convergence point of adhesion signals from α 5 β 1 integrin and syndecan-4

    Article • The Journal of Cell Biology, June 2008, Rockefeller University Press

    Andrew B Goryachev

  49. Dynamics of Cdc42 network embodies a Turing-type mechanism of yeast cell polarity

    Article • FEBS Letters, March 2008, Wiley

    Andrew B Goryachev

  50. From Pathways Databases to Network Models of Switching Behavior

    Article • PLoS Computational Biology, January 2007, PLOS

    Andrew B Goryachev

  51. Improved Hepatocyte Excretory Function by Immediate Presentation of Polarity Cues

    Article • Tissue Engineering, August 2006, Mary Ann Liebert Inc

    Andrew B Goryachev

  52. Global Profiles of Gene Expression Induced by Adrenocorticotropin in Y1 Mouse Adrenal Cells

    Article • Endocrinology, May 2006, Endocrine Society

    Andrew B Goryachev

  53. Systems analysis of a quorum sensing network: Design constraints imposed by the functional requirements, network topology and kinetic constants

    Article • Biosystems, February 2006, Elsevier

    Andrew B Goryachev

  54. Computational Model Explains High Activity and Rapid Cycling of Rho GTPases within Protein Complexes

    Article • PLoS Computational Biology, January 2006, PLOS

    Andrew B Goryachev

  55. Transition to Quorum Sensing in an Agrobacterium Population: A Stochastic Model

    Article • PLoS Computational Biology, September 2005, PLOS

    Lian-Hui Zhang, Andrew B Goryachev

  56. Altered expression of genes involved in hepatic morphogenesis and fibrogenesis are identified by cDNA microarray analysis in biliary atresia

    Article • Hepatology, September 2003, Wiley

    Andrew B Goryachev

  57. Unfolding of Microarray Data

    Article • Journal of Computational Biology, September 2001, Mary Ann Liebert Inc

    Andrew B Goryachev

  58. Herpes Simplex Virus Triggers and Then Disarms a Host Antiviral Response

    Article • Journal of Virology, January 2001, ASM Journals

    Andrew B Goryachev

  59. RNA Polymerase II Subunit Rpb9 Regulates Transcription Elongation in Vivo

    Article • Journal of Biological Chemistry, August 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

    Andrew B Goryachev

  60. SYNCHRONIZATION DEFECT LINES

    Article • International Journal of Bifurcation and Chaos, July 2000, World Scientific Pub Co Pte Lt

    Andrew B Goryachev

  61. SPIRAL WAVES IN MEDIA WITH COMPLEX-EXCITABLE DYNAMICS

    Article • International Journal of Bifurcation and Chaos, November 1999, World Scientific Pub Co Pte Lt

    Andrew B Goryachev

  62. Transitions to Line-Defect Turbulence in Complex Oscillatory Media

    Article • Physical Review Letters, August 1999, American Physical Society (APS)

    Andrew B Goryachev

  63. Synchronization Defects and Broken Symmetry in Spiral Waves

    Article • Physical Review Letters, January 1998, American Physical Society (APS)

    Andrew B Goryachev

  64. Slow manifold structure and the emergence of mixed-mode oscillations

    Article • The Journal of Chemical Physics, August 1997, American Institute of Physics

    Andrew B Goryachev, Peter Strizhak

  65. Structure of complex-periodic and chaotic media with spiral waves

    Article • November 1996, American Physical Society (APS)

    Andrew B Goryachev

  66. Spiral Waves in Chaotic Systems

    Article • Physical Review Letters, March 1996, American Physical Society (APS)

    Andrew B Goryachev

  67. Catastrophic extinction, noise‐stabilized turbulence and unpredictability of competition in a modified Volterra–Lotka model

    Article • Chaos An Interdisciplinary Journal of Nonlinear Science, March 1996, American Institute of Physics

    Andrew B Goryachev