All Stories

  1. New restraints and validation approaches for nucleic acid structures in PDB-REDO

    Article • Acta Crystallographica Section D Structural Biology, August 2021, International Union of Crystallography

    Dr Anastassis Perrakis

  2. LAHMA: structure analysis through local annotation of homology-matched amino acids

    Article • Acta Crystallographica Section D Structural Biology, January 2021, International Union of Crystallography

    Dr Anastassis Perrakis

  3. A community proposal to integrate structural bioinformatics activities in ELIXIR (3D-Bioinfo Community)

    Article • F1000Research, April 2020, Faculty of 1000, Ltd.

    Dr. Alexandre M.J.J. Bonvin, Dr Anastassis Perrakis, rik wierenga, Dr Bohdan Schneider, Dr John M Hancock

  4. A crystal structure of the human protein kinase Mps1 reveals an ordered conformation of the activation loop

    Article • Proteins Structure Function and Bioinformatics, January 2019, Wiley

    Dr Anastassis Perrakis

  5. Characterization and structure determination of a llama-derived nanobody targeting the J-base binding protein 1

    Article • Acta Crystallographica Section F Structural Biology Communications, October 2018, International Union of Crystallography

    Dr Anastassis Perrakis

  6. Homology-based hydrogen bond information improves crystallographic structures in the PDB

    Article • Protein Science, December 2017, Wiley

    Dr Anastassis Perrakis

  7. Negative regulation of urokinase receptor activity by a GPI-specific phospholipase C in breast cancer cells

    Article • eLife, August 2017, eLife

    Dr Anastassis Perrakis

  8. Understanding inhibitor resistance in Mps1 kinase through novel biophysical assays and structures

    Article • Journal of Biological Chemistry, July 2017, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Anastassis Perrakis

  9. Homology-based hydrogen bond information improves crystallographic structures in the PDB

    Article • June 2017, Cold Spring Harbor Laboratory Press

    Dr Anastassis Perrakis

  10. Understanding inhibitor resistance in Mps1 kinase through novel biophysical assays and structures

    Article • February 2017, Cold Spring Harbor Laboratory Press

    Dr Anastassis Perrakis

  11. PLA2G16 represents a switch between entry and clearance of Picornaviridae

    Article • Nature, January 2017, Nature

    Dr Anastassis Perrakis

  12. Structure–Activity Relationships of Small Molecule Autotaxin Inhibitors with a Discrete Binding Mode

    Article • Journal of Medicinal Chemistry, January 2017, American Chemical Society (ACS)

    Dr Anastassis Perrakis

  13. Negative regulation of uPAR activity by a GPI-specific phospholipase C

    Article • December 2016, Cold Spring Harbor Laboratory Press

    Dr Anastassis Perrakis

  14. Glycerophosphodiesterase GDE2 Promotes Neuroblastoma Differentiation through Glypican Release and Is a Marker of Clinical Outcome

    Article • Cancer Cell, December 2016, Elsevier

    Dr Anastassis Perrakis

  15. Structural basis of reversine selectivity in inhibiting Mps1 more potently than aurora B kinase

    Article • Proteins Structure Function and Bioinformatics, October 2016, Wiley

    Dr Anastassis Perrakis

  16. Glycerophosphodiesterase GDE2 Promotes Neuroblastoma Differentiation through Glypican Release and Is a Marker of Clinical Outcome

    Article • Cancer Cell, October 2016, Elsevier

    Dr Anastassis Perrakis

  17. Structural snapshots of the catalytic cycle of the phosphodiesterase Autotaxin

    Article • Journal of Structural Biology, August 2016, Elsevier

    Dr Anastassis Perrakis

  18. Editorial overview: New constructs and expression of proteins

    Article • Current Opinion in Structural Biology, June 2016, Elsevier

    Dr Anastassis Perrakis

  19. Recombinant cloning strategies for protein expression

    Article • Current Opinion in Structural Biology, June 2016, Elsevier

    Dr Anastassis Perrakis

  20. Faculty of 1000 evaluation for Outcome of the First wwPDB/CCDC/D3R Ligand Validation Workshop.

    Article • April 2016, Faculty of 1000, Ltd.

    Dr Anastassis Perrakis

  21. Steroid binding to Autotaxin links bile salts and lysophosphatidic acid signalling

    Article • Nature Communications, April 2016, Nature

    Dr Anastassis Perrakis

  22. Faculty of 1000 evaluation for Structural basis for specific inhibition of Autotaxin by a DNA aptamer.

    Article • April 2016, Faculty of 1000, Ltd.

    Dr Anastassis Perrakis

  23. Faculty of 1000 evaluation for Autotaxin activity increases locally following lung injury, but is not required for pulmonary lysophosphatidic acid production or fibrosis.

    Article • March 2016, Faculty of 1000, Ltd.

    Dr Anastassis Perrakis

  24. Faculty of 1000 evaluation for In vacuo X-ray data collection from graphene-wrapped protein crystals.

    Article • February 2016, Faculty of 1000, Ltd.

    Dr Anastassis Perrakis

  25. Faculty of 1000 evaluation for Collaborative computational project for electron cryo-microscopy.

    Article • January 2016, Faculty of 1000, Ltd.

    Dr Anastassis Perrakis

  26. Data Mining of Macromolecular Structures

    Article • January 2016, Springer Science + Business Media

    Dr Anastassis Perrakis

  27. Crystal structure of GEMC1 coiled-coil domain

    Article • November 2015, Protein Data Bank, Rutgers University

    Dr Anastassis Perrakis

  28. The structure of the GemC1: last of the Geminin family

    Article • Acta Crystallographica Section D Biological Crystallography, October 2015, International Union of Crystallography

    Dr Anastassis Perrakis

  29. MPS1 regulates cell division by competing with microtubules for binding to kinetochores

    Article • Science, June 2015, American Association for the Advancement of Science

    Dr Anastassis Perrakis

  30. The first step of peptide selection in antigen presentation by MHC class I molecules

    Article • Proceedings of the National Academy of Sciences, January 2015, Proceedings of the National Academy of Sciences

    Dr Anastassis Perrakis

  31. Faculty of 1000 evaluation for Automated nucleic acid chain tracing in real time.

    Article • November 2014, Faculty of 1000, Ltd.

    Dr Anastassis Perrakis

  32. Faculty of 1000 evaluation for Archiving raw crystallographic data.

    Article • October 2014, Faculty of 1000, Ltd.

    Dr Anastassis Perrakis

  33. The PDB_REDO server

    Article • IUCrJ, May 2014, International Union of Crystallography

    Dr Anastassis Perrakis

  34. Faculty of 1000 evaluation for Automated identification of elemental ions in macromolecular crystal structures.

    Article • May 2014, Faculty of 1000, Ltd.

    Dr Anastassis Perrakis

  35. Autotaxin: structure-function and signaling

    Article • Journal of Lipid Research, February 2014, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Anastassis Perrakis

  36. Faculty of 1000 evaluation for Automating crystallographic structure solution and refinement of protein-ligand complexes.

    Article • February 2014, Faculty of 1000, Ltd.

    Dr Anastassis Perrakis

  37. Faculty of 1000 evaluation for Crystal Structure of TET2-DNA Complex: Insight into TET-Mediated 5mC Oxidation.

    Article • January 2014, Faculty of 1000, Ltd.

    Dr Anastassis Perrakis

  38. Timely deposition of macromolecular structures is necessary for peer review

    Article • Acta Crystallographica Section D Biological Crystallography, November 2013, International Union of Crystallography

    Dr Anastassis Perrakis

  39. Faculty of 1000 evaluation for Improved low-resolution crystallographic refinement with Phenix and Rosetta.

    Article • October 2013, Faculty of 1000, Ltd.

    Dr Anastassis Perrakis

  40. The Idas:Geminin heterodimeric parallel coiled-coil

    Article • October 2013, Protein Data Bank, Rutgers University

    Dr Anastassis Perrakis

  41. The Geminin and Idas Coiled Coils Preferentially Form a Heterodimer That Inhibits Geminin Function in DNA Replication Licensing

    Article • Journal of Biological Chemistry, September 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Anastassis Perrakis

  42. Faculty of 1000 evaluation for Visual automated macromolecular model building.

    Article • August 2013, Faculty of 1000, Ltd.

    Dr Anastassis Perrakis

  43. Faculty of 1000 evaluation for Better models by discarding data?

    Article • August 2013, Faculty of 1000, Ltd.

    Dr Anastassis Perrakis

  44. Faculty of 1000 evaluation for Report of the wwPDB Small-Angle Scattering Task Force: Data Requirements for Biomolecular Modeling and the PDB.

    Article • June 2013, Faculty of 1000, Ltd.

    Dr Anastassis Perrakis

  45. Faculty of 1000 evaluation for Protein-peptide complex prediction through fragment interaction patterns.

    Article • May 2013, Faculty of 1000, Ltd.

    Dr Anastassis Perrakis

  46. Faculty of 1000 evaluation for Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives.

    Article • April 2013, Faculty of 1000, Ltd.

    Dr Anastassis Perrakis

  47. A TPR domain–containing N-terminal module of MPS1 is required for its kinetochore localization by Aurora B

    Article • The Journal of Cell Biology, April 2013, Rockefeller University Press

    Dr Anastassis Perrakis

  48. Faculty of 1000 evaluation for Techniques, tools and best practices for ligand electron-density analysis and results from their application to deposited crystal structures.

    Article • February 2013, Faculty of 1000, Ltd.

    Dr Anastassis Perrakis

  49. Faculty of 1000 evaluation for Publication guidelines for structural modelling of small-angle scattering data from biomolecules in solution.

    Article • January 2013, Faculty of 1000, Ltd.

    Dr Anastassis Perrakis

  50. Structure–function relationships of autotaxin, a secreted lysophospholipase D

    Article • Advances in Biological Regulation, January 2013, Elsevier

    Dr Anastassis Perrakis

  51. Faculty of 1000 evaluation for A Method for Integrative Structure Determination of Protein-Protein Complexes.

    Article • November 2012, Faculty of 1000, Ltd.

    Dr Anastassis Perrakis

  52. The Polybasic Insertion in Autotaxin α Confers Specific Binding to Heparin and Cell Surface Heparan Sulfate Proteoglycans

    Article • Journal of Biological Chemistry, November 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Anastassis Perrakis

  53. Structure of NPP1, an Ectonucleotide Pyrophosphatase/Phosphodiesterase Involved in Tissue Calcification

    Article • Structure, November 2012, Elsevier

    Dr Anastassis Perrakis

  54. Faculty of 1000 evaluation for Linking crystallographic model and data quality.

    Article • October 2012, Faculty of 1000, Ltd.

    Dr Anastassis Perrakis

  55. Faculty of 1000 evaluation for Autotaxin expression from synovial fibroblasts is essential for the pathogenesis of modeled arthritis.

    Article • September 2012, Faculty of 1000, Ltd.

    Dr Anastassis Perrakis

  56. Faculty of 1000 evaluation for EM-fold: de novo atomic-detail protein structure determination from medium-resolution density maps.

    Article • September 2012, Faculty of 1000, Ltd.

    Dr Anastassis Perrakis

  57. Binding of the J-Binding Protein to DNA Containing Glucosylated hmU (Base J) or 5-hmC: Evidence for a Rapid Conformational Change upon DNA Binding

    Article • Journal of the American Chemical Society, August 2012, American Chemical Society (ACS)

    Dr Anastassis Perrakis

  58. Glucosylated Hydroxymethyluracil, DNA Base J, Prevents Transcriptional Readthrough in Leishmania

    Article • Cell, August 2012, Elsevier

    Dr Anastassis Perrakis

  59. The Vertebrate Mitotic Checkpoint Protein BUBR1 Is an Unusual Pseudokinase

    Article • Developmental Cell, June 2012, Elsevier

    Dr Anastassis Perrakis

  60. ARP/wARP– automated model building and refinement

    Article • April 2012, International Union of Crystallography

    Dr Anastassis Perrakis

  61. PDB_REDO: constructive validation, more than just looking for errors

    Article • Acta Crystallographica Section D Biological Crystallography, March 2012, International Union of Crystallography

    Dr Anastassis Perrakis

  62. Cdt1 and Geminin in DNA Replication Initiation

    Article • January 2012, Springer Science + Business Media

    Dr Anastassis Perrakis

  63. Mechanism of USP7/HAUSP Activation by Its C-Terminal Ubiquitin-like Domain and Allosteric Regulation by GMP-Synthetase

    Article • Molecular Cell, October 2011, Elsevier

    Dr Anastassis Perrakis

  64. A New Generation of Crystallographic Validation Tools for the Protein Data Bank

    Article • Structure, October 2011, Elsevier

    Dr Anastassis Perrakis

  65. Insights into autotaxin: how to produce and present a lipid mediator

    Article • Nature Reviews Molecular Cell Biology, September 2011, Nature

    Dr Anastassis Perrakis

  66. From SPINE to SPINE-2 complexes and beyond

    Article • Journal of Structural Biology, August 2011, Elsevier

    Dr Anastassis Perrakis

  67. Enabling high-throughput ligation-independent cloning and protein expression for the family of ubiquitin specific proteases

    Article • Journal of Structural Biology, August 2011, Elsevier

    Dr Anastassis Perrakis

  68. Expression of protein complexes using multiple Escherichia coli protein co-expression systems: A benchmarking study

    Article • Journal of Structural Biology, August 2011, Elsevier

    Dr Anastassis Perrakis

  69. Investigating a macromolecular complex: The toolkit of methods

    Article • Journal of Structural Biology, August 2011, Elsevier

    Dr Anastassis Perrakis

  70. Structure-Based Design of Novel Boronic Acid-Based Inhibitors of Autotaxin

    Article • Journal of Medicinal Chemistry, July 2011, American Chemical Society (ACS)

    Dr Anastassis Perrakis

  71. Native mass spectrometry provides direct evidence for DNA mismatch-induced regulation of asymmetric nucleotide binding in mismatch repair protein MutS

    Article • Nucleic Acids Research, July 2011, Oxford University Press (OUP)

    Dr Anastassis Perrakis

  72. Idas, a Novel Phylogenetically Conserved Geminin-related Protein, Binds to Geminin and Is Required for Cell Cycle Progression

    Article • Journal of Biological Chemistry, May 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Anastassis Perrakis

  73. The structural basis for recognition of base J containing DNA by a novel DNA binding domain in JBP1

    Article • Nucleic Acids Research, March 2011, Oxford University Press (OUP)

    Dr Anastassis Perrakis

  74. Structural basis of substrate discrimination and integrin binding by autotaxin

    Article • Nature Structural & Molecular Biology, January 2011, Nature

    Dr Anastassis Perrakis

  75. Target highlights in CASP9: Experimental target structures for the critical assessment of techniques for protein structure prediction

    Article • Proteins Structure Function and Bioinformatics, January 2011, Wiley

    Dr Anastassis Perrakis

  76. Systematic Bioinformatics and Experimental Validation of Yeast Complexes Reduces the Rate of Attrition during Structural Investigations

    Article • Structure, September 2010, Elsevier

    Dr Anastassis Perrakis

  77. Mammalian cell expression, purification, crystallization and microcrystal data collection of autotaxin/ENPP2, a secreted mammalian glycoprotein

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, August 2010, International Union of Crystallography

    Dr Gwyndaf Evans, Dr Anastassis Perrakis

  78. Human Cdt1:Geminin complex

    Article • October 2009, Protein Data Bank, Rutgers University

    Dr Anastassis Perrakis

  79. UV-Induced Ligand Exchange in MHC Class I Protein Crystals

    Article • Journal of the American Chemical Society, September 2009, American Chemical Society (ACS)

    Dr Anastassis Perrakis

  80. Class I Major Histocompatibility Complexes Loaded by a Periodate Trigger

    Article • Journal of the American Chemical Society, September 2009, American Chemical Society (ACS)

    Dr Anastassis Perrakis

  81. Use of Acetylcholine Binding Protein in the Search for Novel α7 Nicotinic Receptor Ligands. In Silico Docking, Pharmacological Screening, and X-ray Analysis†

    Article • Journal of Medicinal Chemistry, April 2009, American Chemical Society (ACS)

    Dr Anastassis Perrakis

  82. Insights into the DNA cleavage mechanism of human LINE-1 retrotransposon endonuclease

    Article • Proteins Structure Function and Bioinformatics, March 2009, Wiley

    Dr Anastassis Perrakis, Dr. Alexandre M.J.J. Bonvin

  83. “Conditional Restraints”: Restraining the Free Atoms in ARP/wARP

    Article • Structure, February 2009, Elsevier

    Dr Anastassis Perrakis

  84. Advances in automatic model building and structure completion in the context ofARP/wARP

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2008, International Union of Crystallography

    Dr Anastassis Perrakis

  85. Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7

    Article • Nature Protocols, June 2008, Nature

    Dr Anastassis Perrakis

  86. Polo-box domains confer target specificity to the Polo-like kinase family

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, June 2008, Elsevier

    Dr Anastassis Perrakis

  87. A knowledge-driven approach for crystallographic protein model completion

    Article • Acta Crystallographica Section D Biological Crystallography, March 2008, International Union of Crystallography

    Dr Anastassis Perrakis

  88. Assembly of Protein Complexes by Coexpression in Prokaryotic and Eukaryotic Hosts: an Overview

    Article • January 2008, Springer Science + Business Media

    Dr Anastassis Perrakis

  89. ARP/wARPand molecular replacement: the next generation

    Article • Acta Crystallographica Section D Biological Crystallography, December 2007, International Union of Crystallography

    Dr Anastassis Perrakis

  90. RNA-Binding Protein Dnd1 Inhibits MicroRNA Access to Target mRNA

    Article • Cell, December 2007, Elsevier

    Dr Anastassis Perrakis

  91. Determinants for DNA target structure selectivity of the human LINE-1 retrotransposon endonuclease

    Article • Nucleic Acids Research, July 2007, Oxford University Press (OUP)

    Dr Anastassis Perrakis

  92. The protein that binds to DNA base J in trypanosomatids has features of a thymidine hydroxylase

    Article • Nucleic Acids Research, March 2007, Oxford University Press (OUP)

    Dr Anastassis Perrakis, Robert Hausinger

  93. Assessment of automatic ligand building inARP/wARP

    Article • Acta Crystallographica Section D Biological Crystallography, December 2006, International Union of Crystallography

    Dr Anastassis Perrakis

  94. Polo-like Kinase-1 Controls Proteasome-Dependent Degradation of Claspin during Checkpoint Recovery

    Article • Current Biology, October 2006, Elsevier

    Dr Anastassis Perrakis

  95. Co-expression of protein complexes in prokaryotic and eukaryotic hosts: experimental procedures, database tracking and case studies

    Article • Acta Crystallographica Section D Biological Crystallography, September 2006, International Union of Crystallography

    Dr Anastassis Perrakis

  96. Modelling bound ligands with ARP/wARP

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2006, International Union of Crystallography

    Dr Anastassis Perrakis

  97. Structure and E3-ligase activity of the Ring–Ring complex of Polycomb proteins Bmi1 and Ring1b

    Article • The EMBO Journal, May 2006, Wiley

    Dr Anastassis Perrakis

  98. Selectivity and Promiscuity in Eph Receptors

    Article • Structure, February 2006, Elsevier

    Dr Anastassis Perrakis

  99. Towards rationalization of crystallization screening for small- to medium-sized academic laboratories: the PACT/JCSG+ strategy

    Article • Acta Crystallographica Section D Biological Crystallography, September 2005, International Union of Crystallography

    Dr Anastassis Perrakis

  100. Modeling and Experimental Validation of the Binary Complex of the Plectin Actin-binding Domain and the First Pair of Fibronectin Type III (FNIII) Domains of the β4 Integrin

    Article • Journal of Biological Chemistry, April 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Anastassis Perrakis

  101. Inhibition of Autotaxin by Lysophosphatidic Acid and Sphingosine 1-Phosphate

    Article • Journal of Biological Chemistry, March 2005, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Anastassis Perrakis

  102. Model building and refinement

    Article • Acta Crystallographica Section D Biological Crystallography, November 2004, International Union of Crystallography

    Dr Anastassis Perrakis

  103. Towards complete validated models in the next generation ofARP/wARP

    Article • Acta Crystallographica Section D Biological Crystallography, November 2004, International Union of Crystallography

    Dr Anastassis Perrakis

  104. Developments in theCCP4 molecular-graphics project

    Article • Acta Crystallographica Section D Biological Crystallography, November 2004, International Union of Crystallography

    Dr Anastassis Perrakis

  105. Crystal Structure of the Targeting Endonuclease of the Human LINE-1 Retrotransposon

    Article • Structure, June 2004, Elsevier

    Dr Anastassis Perrakis

  106. Breaking good resolutions with ARP/wARP

    Article • Journal of Synchrotron Radiation, November 2003, International Union of Crystallography

    Dr Anastassis Perrakis

  107. ARP⧸wARP and Automatic Interpretation of Protein Electron Density Maps

    Article • January 2003, Elsevier

    Dr Anastassis Perrakis

  108. The ARP/wARP suite for the automation of crystal structure determination

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2002, International Union of Crystallography

    Dr Anastassis Perrakis

  109. Ptprj is a candidate for the mouse colon-cancer susceptibility locus Scc1 and is frequently deleted in human cancers

    Article • Nature Genetics, June 2002, Nature

    Dr Anastassis Perrakis

  110. ARP/wARP's model-building algorithms. I. The main chain

    Article • Acta Crystallographica Section D Biological Crystallography, May 2002, International Union of Crystallography

    Dr Anastassis Perrakis

  111. ARP/wARP and molecular replacement

    Article • Acta Crystallographica Section D Biological Crystallography, September 2001, International Union of Crystallography

    Dr Anastassis Perrakis

  112. Structure elucidation of β-mannanase: from the electron-density map to the DNA sequence

    Article • Acta Crystallographica Section D Biological Crystallography, January 2001, International Union of Crystallography

    Dr Anastassis Perrakis

  113. Apotheosis, not apocalypse: methods in protein crystallography

    Article • Acta Crystallographica Section D Biological Crystallography, November 2000, International Union of Crystallography

    Dr Anastassis Perrakis

  114. ARP/wARP: Procedures for automated model building and refinement

    Article • Acta Crystallographica Section A Foundations of Crystallography, August 2000, International Union of Crystallography

    Dr Anastassis Perrakis

  115. The X-ray crystal structure of neuronal Sec1 from squid sheds new light on the role of this protein in exocytosis

    Article • Structure, July 2000, Elsevier

    Dr Anastassis Perrakis

  116. Protein microcrystals and the design of a microdiffractometer: current experience and plans at EMBL and ESRF/ID13

    Article • Acta Crystallographica Section D Biological Crystallography, October 1999, International Union of Crystallography

    Dr Anastassis Perrakis

  117. Automated protein model building combined with iterative structure refinement

    Article • Nature Structural Biology, May 1999, Springer Science + Business Media

    Dr Anastassis Perrakis

  118. Molecular, crystal and solution structure of a β-cyclodextrin complex with the bromide salt of 2-(3-dimethylaminopropyl)tricyclo[3.3.1.13,7]decan-2-ol, a potent antimicrobial drug

    Article • Carbohydrate Research, April 1999, Elsevier

    Dr Anastassis Perrakis

  119. Small is beautiful: protein micro-crystallography

    Article • Nature Structural Biology, August 1998, Nature

    Dr Anastassis Perrakis

  120. Accelerated X-ray Structure Elucidation of a 36 kDa Muramidase/Transglycosylase Using wARP

    Article • Acta Crystallographica Section D Biological Crystallography, January 1998, International Union of Crystallography

    Dr Anastassis Perrakis

  121. Evolution of immunoglobulin-like modules in chitinases: their structural flexibility and functional implications

    Article • Folding and Design, October 1997, Elsevier

    Dr Anastassis Perrakis

  122. Crystal structure of the specific DNA-binding domain of Tc3 transposase of C.elegans in complex with transposon DNA

    Article • The EMBO Journal, October 1997, Wiley

    Dr Anastassis Perrakis

  123. Crystal Structure of Murine/Human Ubc9 Provides Insight into the Variability of the Ubiquitin-conjugating System

    Article • Journal of Biological Chemistry, August 1997, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Anastassis Perrakis

  124. Substrate-Assisted Catalysis Unifies Two Families of Chitinolytic Enzymes

    Article • Journal of the American Chemical Society, August 1997, American Chemical Society (ACS)

    Dr Anastassis Perrakis

  125. Crystal structure of UDP-N-acetylglucosamine enolpyruvyltransferase, the target of the antibiotic fosfomycin

    Article • Structure, September 1996, Elsevier

    Dr Anastassis Perrakis

  126. Bacterial chitobiase structure provides insight into catalytic mechanism and the basis of Tay–Sachs disease

    Article • Nature Structural Biology, July 1996, Nature

    Dr Anastassis Perrakis

  127. The Crystal Structure of the Complexes of Concanavalin A with 4′-Nitrophenyl-α-d-mannopyranoside and 4′-Nitrophenyl-α-d-glucopyranoside

    Article • Journal of Structural Biology, May 1996, Elsevier

    Dr Anastassis Perrakis

  128. Crystal structure of a bacterial chitinase at 2.3 Å resolution

    Article • Structure, December 1994, Elsevier

    Dr Anastassis Perrakis

  129. Evolutionary divergence and conservation of trypsin

    Article • Protein Engineering Design and Selection, January 1994, Oxford University Press (OUP)

    Dr Anastassis Perrakis