All Stories

  1. Design and synthesis of potent hydroxamate inhibitors with increased selectivity within the gelatinase family

    Article • Organic & Biomolecular Chemistry, January 2015, Royal Society of Chemistry

    Dr Ana Ramos

  2. Synthesis, biological activity and structural study of new benzotriazole-based protein kinase CK2 inhibitors

    Article • RSC Advances, January 2015, Royal Society of Chemistry

    Dr Ana Ramos

  3. Targeting Matrix Metalloproteinases: Exploring the Dynamics of the S1′ Pocket in the Design of Selective, Small Molecule Inhibitors

    Article • Journal of Medicinal Chemistry, December 2014, American Chemical Society (ACS)

    Dr Ana Ramos

  4. Human Protein Kinase CK2 Phosphorylates Matrix Metalloproteinase 2 and Inhibits its Activity

    Article • ChemBioChem, July 2014, Wiley

    Dr Ana Ramos

  5. An Integrated Computational and Experimental Approach to Gaining Selectivity for MMP-2 within the Gelatinase Subfamily

    Article • ChemBioChem, January 2014, Wiley

    Dr Ana Ramos

  6. Dietary gallic acid and anthocyanin cytotoxicity on human fibrosarcoma HT1080 cells. A study on the mode of action

    Article • Food & Function, January 2014, Royal Society of Chemistry

    Dr Ana Ramos

  7. New clicked thiirane derivatives as gelatinase inhibitors: the relevance of the P1′ segment

    Article • RSC Advances, January 2014, Royal Society of Chemistry

    Dr Ana Ramos

  8. Progress towards water-soluble triazole-based selective MMP-2 inhibitors

    Article • Organic & Biomolecular Chemistry, January 2013, Royal Society of Chemistry

    Dr Ana Ramos

  9. New clicked full agonists of the estrogen receptor β

    Article • RSC Advances, January 2013, Royal Society of Chemistry

    Dr Sebastian Demkowicz, Dr Ana Ramos

  10. Identification of first proadrenomedullin N-terminal 20 peptide (PAMP) modulator by means of virtual screening and NMR interaction experiments

    Article • European Journal of Medicinal Chemistry, September 2012, Elsevier

    Dr Ana Ramos

  11. MMP-2 Selectivity in Hydroxamate-Type Inhibitors

    Article • Current Medicinal Chemistry, March 2012, Bentham Science Publishers

    Dr Ana Ramos

  12. Towards β-selectivity in functional estrogen receptor antagonists

    Article • Organic & Biomolecular Chemistry, January 2012, Royal Society of Chemistry

    Dr Sebastian Demkowicz, Dr Ana Ramos

  13. Structure of micelle-bound adrenomedullin: A first step toward the analysis of its interactions with receptors and small molecules

    Article • Biopolymers, August 2011, Wiley

    Dr Ana Ramos

  14. Multisite-directed inhibitors of protein kinase CK2: new challenges

    Article • Molecular and Cellular Biochemistry, July 2011, Springer Science + Business Media

    Dr Ana Ramos

  15. Potent “Clicked” MMP2 Inhibitors: Synthesis, Molecular Modeling and Biological Exploration

    Article • Organic & Biomolecular Chemistry, January 2011, Royal Society of Chemistry

    Dr Ana Ramos

  16. In the search of a new prototype in the design of CK2 inhibitors

    Article • ARKIVOC, November 2010, University of Michigan Library

    Dr Ana Ramos

  17. ChemInform Abstract: Extension of the Aza-di-π-methane Reaction to Stable Derivatives. Photochemical Cyclization of β,γ-Unsaturated Oxime Acetates.

    Article • ChemInform, August 2010, Wiley

    Dr Ana Ramos

  18. ChemInform Abstract: A Study on the Scope of the Photochemical 1,3-Migration of Oximino Groups in β,γ-Unsaturated Oximes and Oxime Derivatives.

    Article • ChemInform, August 2010, Wiley

    Dr Ana Ramos

  19. ChemInform Abstract: The Electron Transfer Mediated Photochemistry of Some Unsaturated Nitrogen-Containing Compounds

    Article • ChemInform, August 2010, Wiley

    Dr Ana Ramos

  20. The design of novel 17β-hydroxysteroid dehydrogenase type 3 inhibitors

    Article • Molecular and Cellular Endocrinology, March 2009, Elsevier

    Dr Ana Ramos

  21. Small-Molecule Negative Modulators of Adrenomedullin: Design, Synthesis, and 3D-QSAR Study

    Article • ChemMedChem, August 2008, Wiley

    Dr Ana Ramos

  22. SPR label-free ranking of small molecule negative modulators of adrenomedullin

    Article • European Journal of Cancer Supplements, July 2008, Elsevier

    Dr Ana Ramos

  23. New scaffolds for the design of selective estrogen receptor modulators

    Article • Organic & Biomolecular Chemistry, January 2008, Royal Society of Chemistry

    Dr Ana Ramos

  24. Adrenomedullin: a new and promising target for drug discovery

    Article • Expert Opinion on Therapeutic Targets, March 2006, Informa Healthcare

    Dr Ana Ramos

  25. Pyrazolo[3,4- c ]pyridazines as Novel and Selective Inhibitors of Cyclin-Dependent Kinases

    Article • Journal of Medicinal Chemistry, November 2005, American Chemical Society (ACS)

    Dr Ana Ramos

  26. Adrenomedullin: a new target for the design of small molecule modulators with promising pharmacological activities

    Article • European Journal of Medicinal Chemistry, August 2005, Elsevier

    Dr Ana Ramos

  27. New Analogues of Amonafide and Elinafide, Containing Aromatic Heterocycles:  Synthesis, Antitumor Activity, Molecular Modeling, and DNA Binding Properties

    Article • Journal of Medicinal Chemistry, March 2004, American Chemical Society (ACS)

    Dr Ana Ramos

  28. Synthesis and biological evaluation of analogues of butyrolactone I and molecular model of its interaction with CDK2

    Article • Organic & Biomolecular Chemistry, January 2004, Royal Society of Chemistry

    Dr Ana Ramos

  29. Chromophore-Modified Bisnaphthalimides:  DNA Recognition, Topoisomerase Inhibition, and Cytotoxic Properties of Two Mono- and Bisfuronaphthalimides †

    Article • Biochemistry, April 2003, American Chemical Society (ACS)

    Dr Ana Ramos

  30. Synthesis, biological evaluation and DNA binding properties of novel mono and bisnaphthalimides

    Article • Organic & Biomolecular Chemistry, January 2003, Royal Society of Chemistry

    Dr Ana Ramos

  31. Synthesis, Antitumor Activity, Molecular Modeling, and DNA Binding Properties of a New Series of Imidazonaphthalimides

    Article • Journal of Medicinal Chemistry, December 2002, American Chemical Society (ACS)

    Dr Ana Ramos

  32. Intercalators as Anticancer Drugs

    Article • Current Pharmaceutical Design, November 2001, Bentham Science Publishers

    Dr Ana Ramos

  33. Naphthalimides as Anticancer Agents: Synthesis and Biological Activity

    Article • Current Medicinal Chemistry - Anti-Cancer Agents, November 2001, Bentham Science Publishers

    Dr Ana Ramos

  34. A study on the scope of the photochemical ring contraction of substituted 2-amino-3-cyano-4H-pyrans to cyclobutenes: crystal structure of 3-carbamoyl-3-cyano-1-ethoxycarbonyl-4-isopropyl-2-phenylcyclobutene

    Article • Journal of the Chemical Society Perkin Transactions 1, January 1997, Royal Society of Chemistry

    Dr Ana Ramos

  35. Novel photochemical behaviour of the oximes and hydrazones of β,γ-unsaturated carbonyl compounds

    Article • Journal of the Chemical Society Perkin Transactions 1, January 1997, Royal Society of Chemistry

    Dr Ana Ramos

  36. Bis[5,5-bis(4-methoxyphenyl)-3,3-dimethyl-2-tetrahydrofuranyl] Ether

    Article • Acta Crystallographica Section C Crystal Structure Communications, September 1996, International Union of Crystallography

    Dr Ana Ramos

  37. A study on the scope of the photochemical 1,3-migration of oximino groups in β,γ-unsaturated oximes and oxime derivatives

    Article • Journal of the Chemical Society Perkin Transactions 1, January 1996, Royal Society of Chemistry

    Dr Ana Ramos

  38. Unexpected Oxadi-π-methane Rearrangement of β,γ-Unsaturated Aldehydes

    Article • The Journal of Organic Chemistry, January 1996, American Chemical Society (ACS)

    Dr Ana Ramos

  39. Novel photocyclization of β,γ-unsaturated oximes

    Article • Recueil des Travaux Chimiques des Pays-Bas, January 1995, Wiley

    Dr Ana Ramos

  40. A Study of the Competition between the Di-.pi.-methane and the Azadi-.pi.-methane Processes in 2-Vinyl-.beta.,.gamma.-unsaturated Oxime Derivatives. The Novel Azadi-.pi.-methane Reactivity of .beta.,.gamma.-Unsaturated Oximes

    Article • The Journal of Organic Chemistry, December 1994, American Chemical Society (ACS)

    Dr Ana Ramos

  41. The aza-di-π-methane rearrangement of β-γ-unsaturated oximes

    Article • Tetrahedron Letters, May 1994, Elsevier

    Dr Ana Ramos

  42. Photochemical synthesis of oxime acetates derivatives of 1-carbaldehydobicyclo[n.1.0]alkanes by the aza-di-π-methane rearrangement.

    Article • Tetrahedron, August 1993, Elsevier

    Dr Ana Ramos

  43. Extension of the aza-di-π-methane reaction to stable derivatives. Photochemical cyclization of β,γ-unsaturated oxime acetates

    Article • Journal of the Chemical Society Perkin Transactions 1, January 1991, Royal Society of Chemistry

    Professor Fernando Langa, Dr Ana Ramos

  44. Synthesis of cyclobutenes by the novel photochemical ring contraction of 4-substituted 2-amino-3,5-dicyano-6-phenyl-4H-pyrans

    Article • The Journal of Organic Chemistry, June 1989, American Chemical Society (ACS)

    Dr Ana Ramos

  45. Photochemical reactivity of imines from benzil mono-oxime esters

    Article • Journal of the Chemical Society Perkin Transactions 1, January 1989, Royal Society of Chemistry

    Dr Ana Ramos

  46. Synthesis of α-Imino Oximes from α-Hydroxyimino Ketones

    Article • Synthesis, January 1989, Thieme Publishing Group

    Dr Ana Ramos

  47. Unexpected reactivity of the anion derived from benzophenone benzoylhydrazone in the presence of electrophiles

    Article • Tetrahedron Letters, January 1988, Elsevier

    Dr Ana Ramos

  48. Retro-ene reactions of N-substituted derivatives of 4-aza-2,2-dimethyl-1-phenyl-3-butenone and related compounds

    Article • The Journal of Organic Chemistry, July 1987, American Chemical Society (ACS)

    Dr Ana Ramos

  49. SYNTHESIS OF DIIMINES FROM 1,2-DICARBONYL COMPOUNDS BY DIRECT CATALYZED CONDENSATION

    Article • Organic Preparations and Procedures International, April 1987, Taylor & Francis

    Dr Ana Ramos

  50. A novel photochemical ring contraction of 4H-pyrans. A new route to selectively substituted cyclobutenes

    Article • Journal of the Chemical Society Chemical Communications, January 1987, Royal Society of Chemistry

    Dr Ana Ramos

  51. Photochemical reactivity of aldimines from 2,2-dimethyl-3-oxo-3-phenylpropanal

    Article • Journal of the Chemical Society Perkin Transactions 1, January 1986, Royal Society of Chemistry

    Dr Ana Ramos

  52. A novel retro-ene reaction the fragmentation of N-Benzyl-2-benzoyl-2-methylpropanimine

    Article • Tetrahedron Letters, January 1982, Elsevier

    Dr Ana Ramos