All Stories

  1. Transcriptome-wide investigation of stop codon readthrough in Saccharomyces cerevisiae

    Article • PLoS Genetics, April 2021, PLOS

    Allan Jacobson

  2. Nonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the Story

    Article • Annual Review of Genetics, November 2015, Annual Reviews

    Allan Jacobson, Dr Feng He

  3. NMD: At the crossroads between translation termination and ribosome recycling

    Article • Biochimie, July 2015, Elsevier

    Allan Jacobson

  4. Nonsense suppression by near-cognate tRNAs employs alternative base pairing at codon positions 1 and 3

    Article • Proceedings of the National Academy of Sciences, March 2015, Proceedings of the National Academy of Sciences

    Allan Jacobson

  5. A Highly Conserved Region Essential for NMD in the Upf2 N-Terminal Domain

    Article • Journal of Molecular Biology, November 2014, Elsevier

    Allan Jacobson, Claudia Millán, Marc GRAILLE

  6. Yeast Edc3 Targets RPS28B mRNA for Decapping by Binding to a 3' Untranslated Region Decay-Inducing Regulatory Element

    Article • Molecular and Cellular Biology, February 2014, ASM Journals

    Allan Jacobson, Dr Feng He

  7. The intimate relationships of mRNA decay and translation

    Article • Trends in Genetics, December 2013, Elsevier

    Allan Jacobson

  8. Intra- and Intermolecular Regulatory Interactions in Upf1, the RNA Helicase Central to Nonsense-Mediated mRNA Decay in Yeast

    Article • Molecular and Cellular Biology, October 2013, ASM Journals

    Allan Jacobson, Dr Feng He

  9. Ataluren as an Agent for Therapeutic Nonsense Suppression

    Article • Annual Review of Medicine, January 2013, Annual Reviews

    Allan Jacobson

  10. NMD: a multifaceted response to premature translational termination

    Article • Nature Reviews Molecular Cell Biology, October 2012, Springer Science + Business Media

    Allan Jacobson

  11. Testing the faux-UTR model for NMD: Analysis of Upf1p and Pab1p competition for binding to eRF3/Sup35p

    Article • Biochimie, July 2012, Elsevier

    Allan Jacobson

  12. RNA decay modulates gene expression and controls its fidelity

    Article • Wiley Interdisciplinary Reviews - RNA, June 2010, Wiley

    Allan Jacobson

  13. Degradation of YRA1 Pre-mRNA in the Cytoplasm Requires Translational Repression, Multiple Modular Intronic Elements, Edc3p, and Mex67p

    Article • PLoS Biology, April 2010, PLOS

    Allan Jacobson

  14. Targeting post-transcriptional control for drug discovery

    Article • RNA Biology, July 2009, Taylor & Francis

    Allan Jacobson

  15. PTC124 for cystic fibrosis – Authors' reply

    Article • The Lancet, April 2009, Elsevier

    Allan Jacobson

  16. Translation factors promote the formation of two states of the closed-loop mRNP

    Article • Nature, May 2008, Springer Science + Business Media

    Allan Jacobson

  17. Qualitative and Quantitative Assessment of the Activity of the Yeast Nonsense-Mediated mRNA Decay Pathway

    Article • January 2008, Elsevier

    Allan Jacobson

  18. YRA1 Autoregulation Requires Nuclear Export and Cytoplasmic Edc3p-Mediated Degradation of Its Pre-mRNA

    Article • Molecular Cell, February 2007, Elsevier

    Allan Jacobson

  19. The Use of Fungal In Vitro Systems for Studying Translational Regulation

    Article • January 2007, Elsevier

    Allan Jacobson

  20. Early nonsense: mRNA decay solves a translational problem

    Article • Nature Reviews Molecular Cell Biology, June 2006, Springer Science + Business Media

    Allan Jacobson

  21. Ribosome Occupancy of the Yeast CPA1 Upstream Open Reading Frame Termination Codon Modulates Nonsense-Mediated mRNA Decay

    Article • Molecular Cell, November 2005, Elsevier

    Allan Jacobson

  22. The end justifies the means

    Article • Nature Structural & Molecular Biology, June 2005, Springer Science + Business Media

    Allan Jacobson

  23. A faux 3′-UTR promotes aberrant termination and triggers nonsense- mediated mRNA decay

    Article • November 2004, Nature

    Allan Jacobson

  24. Regulation of mRNA Decay

    Article • Molecular Cell, July 2004, Elsevier

    Allan Jacobson

  25. Genome-Wide Analysis of mRNAs Regulated by the Nonsense-Mediated and 5′ to 3′ mRNA Decay Pathways in Yeast

    Article • Molecular Cell, December 2003, Elsevier

    Allan Jacobson

  26. Replacement of the yeast TRP4 3??? untranslated region by a hammerhead ribozyme results in a stable and efficiently exported mRNA that lacks a poly(A) tail

    Article • RNA, March 2002, Cold Spring Harbor Laboratory Press

    Allan Jacobson

  27. Characterization of the biochemical properties of the human Upf1 gene product that is involved in nonsense-mediated mRNA decay

    Article • RNA, September 2000, Cold Spring Harbor Laboratory Press

    Allan Jacobson

  28. Overexpression of truncated Nmd3p inhibits protein synthesis in yeast

    Article • RNA, August 1999, Cold Spring Harbor Laboratory Press

    Allan Jacobson

  29. A Genetic Approach to Mapping Coding Region Determinants of mRNA Instability in Yeast

    Article • January 1997, Elsevier

    Allan Jacobson

  30. Interrelationships of the Pathways of mRNA Decay and Translation in Eukaryotic Cells

    Article • Annual Review of Biochemistry, June 1996, Annual Reviews

    Allan Jacobson

  31. Changes in the Length of Poly(A) Tails and their Effects on mRNA Translation and Turnover

    Article • January 1996, Springer Science + Business Media

    Allan Jacobson

  32. Regulation of Eukaryotic Gene Expression at the Level of mRNA Stability: Emergence of General Principles

    Article • January 1996, Springer Science + Business Media

    Allan Jacobson

  33. Nonsense-mediated mRNA Decay in Yeast

    Article • January 1994, Elsevier

    Allan Jacobson

  34. mRNA Turnover in Saccharomyces cerevisiae

    Article • January 1993, Elsevier

    Allan Jacobson

  35. Identification of the cis-acting sequences and trans-acting factors involved in nonsense-mediated mRNA decay

    Article • January 1993, Springer Science + Business Media

    Allan Jacobson

  36. Contributors

    Article • January 1993, Elsevier

    Allan Jacobson

  37. Turnover of mRNA in prokaryotes and lower eukaryotes

    Article • Current Biology, October 1992, Elsevier

    Allan Jacobson

  38. A coding region segment is necessary, but not sufficient for rapid decay of the HIS3 mRNA in yeast

    Article • Gene, May 1992, Elsevier

    Allan Jacobson

  39. Turnover of mRNA in prokaryotes and lower eukaryotes

    Article • Current Opinion in Genetics & Development, January 1992, Elsevier

    Allan Jacobson

  40. Sequence elements that affect mRNA translational activity in developingDictyostelium cells

    Article • Developmental Genetics, January 1991, Wiley

    Allan Jacobson

  41. [29] Measurement of mRNA decay rates in Saccharomyces cerevisiae

    Article • January 1991, Elsevier

    Allan Jacobson

  42. Tales of poly(A): a review

    Article • Gene, July 1990, Elsevier

    Allan Jacobson

  43. Regulation of mRNA Stability in Yeast

    Article • January 1990, Springer Science + Business Media

    Allan Jacobson

  44. Post-transcriptional regulation of ribosomal protein gene expression during development inDictyostelium discoideum

    Article • Developmental Genetics, January 1988, Wiley

    Allan Jacobson

  45. Regulation of mRNA stability and the poly(A) problem inDictyostelium discoideum

    Article • Developmental Genetics, January 1988, Wiley

    Allan Jacobson

  46. Nucleotide sequence and characterization of the transcript of a Dictyostelium ribosomal protein gene

    Article • Nucleic Acids Research, January 1988, Oxford University Press (OUP)

    Allan Jacobson

  47. [25] Purification and fractionation of poly(A)+ RNA

    Article • January 1987, Elsevier

    Allan Jacobson

  48. Nucleotide sequence and characterization of the transcript of a Dictyostelium ribosomal protein gene

    Article • Nucleic Acids Research, January 1987, Oxford University Press (OUP)

    Allan Jacobson

  49. Identification and characterization of developmentally regulated mRNP proteins of Dictyostelium discoideum

    Article • Developmental Biology, July 1986, Elsevier

    Allan Jacobson

  50. Ribosomal proteins are encoded by single copy genes in Dictyostelium discoideum

    Article • Gene, January 1986, Elsevier

    Allan Jacobson

  51. Translational control during early dictyostelium development: Possible involvement of poly(A) sequences

    Article • Cell, April 1984, Elsevier

    Allan Jacobson

  52. Intron bypass: a rapid procedure for eliminating introns from cloned genomic DNA and its application to a cellulase gene

    Article • Nucleic Acids Research, January 1984, Oxford University Press (OUP)

    Allan Jacobson

  53. Messenger RNA half-life in Dictyostelium discoideum

    Article • Developmental Biology, January 1983, Elsevier

    Allan Jacobson

  54. Possible Involvement of poly(A) in protein synthesks

    Article • Nucleic Acids Research, January 1983, Oxford University Press (OUP)

    Allan Jacobson

  55. Partial purification of a developmentally regulated messenger RNA from Dictyostelium discoideum by thermal elution from poly(U)-Sepharose

    Article • Journal of Molecular Biology, August 1981, Elsevier

    Allan Jacobson

  56. EVIDENCE FOR THE TRANSFORMATION OF DICTYOSTELIUM DISCOIDEUM WITH HOMOLOGOUS DNA

    Article • January 1981, Elsevier

    Allan Jacobson

  57. Messenger RNA stability in Dictyostelium discoideum

    Article • Journal of Molecular Biology, August 1980, Elsevier

    Allan Jacobson

  58. Similarity of the primary sequences of ribosomal RNAs isolated from vegetative and developing cells of Dictyostelium discoideum

    Article • Developmental Biology, August 1980, Elsevier

    Allan Jacobson

  59. Fractionation and functional analysis of newly synthesized and decaying messenger RNAs from vegetative cells of Dictyostelium discoideum

    Article • Journal of Molecular Biology, March 1979, Elsevier

    Allan Jacobson

  60. Synthesis of messenger and ribosomal RNA precursors in isolated nuclei of the cellular slime mold Dictyostelium discoideum

    Article • Journal of Molecular Biology, January 1974, Elsevier

    Allan Jacobson

  61. Oligonucleotide fingerprinting of Hela cell 5 S RNA labeled in vitro with 125I

    Article • Molecular Biology Reports, December 1973, Springer Science + Business Media

    Allan Jacobson

  62. Use of exhaustive nucleic acid hybridization for determining the amount and size distribution of newly synthesized bacterial message RNA

    Article • Biochemical Genetics, October 1973, Springer Science + Business Media

    Allan Jacobson

  63. A simple and inexpensive procedure for preparative polyacrylamide gel electrophoresis of RNA

    Article • Analytical Biochemistry, August 1973, Elsevier

    Allan Jacobson

  64. Isolation and Hybridization Kinetics of Messenger RNA from Dictyostelium discoideum

    Article • Nature New Biology, October 1972, Springer Science + Business Media

    Allan Jacobson

  65. Genetic complementation between Escherichia coli RNA polymerase mutants

    Article • Biochemical and Biophysical Research Communications, September 1971, Elsevier

    Allan Jacobson