All Stories

  1. Cover Image, Volume 113, Number 12, December 2016

    Article • Biotechnology and Bioengineering, October 2016, Wiley

    Alexis Bemelmans

  2. AMYLOID DEPOSITION IS TRIGGERED BY ALZHEIMER'S DISEASE BRAIN HOMOGENATES INOCULATION IN WILD-TYPE MICE WITH FOCAL AD-LIKE PATHOLOGY

    Article • Alzheimer s & Dementia, July 2016, Elsevier

    Alexis Bemelmans

  3. Ultramicroscopy as a novel tool to unravel the tropism of AAV gene therapy vectors in the brain

    Article • Scientific Reports, June 2016, Nature

    Alexis Bemelmans

  4. 59. APPsα Gene Therapy for Alzheimer's Disease

    Article • Molecular Therapy, May 2016, Elsevier

    Alexis Bemelmans

  5. mRNAtrans-splicing in gene therapy for genetic diseases

    Article • Wiley Interdisciplinary Reviews - RNA, March 2016, Wiley

    Alexis Bemelmans

  6. Non-human primate model of tauopathy

    Article • Alzheimer s & Dementia, July 2015, Elsevier

    Professor Nicole Déglon, Alexis Bemelmans

  7. Gene transfer of both app and ps1 induces hippocampal impairments close to human early phases of Alzheimer’s disease

    Article • Alzheimer s & Dementia, July 2015, Elsevier

    Professor Nicole Déglon, Alexis Bemelmans

  8. Improved amyloid pathology contrasting with unexpected memory defects following astrocytic ApoE-e2 overexpression in hippocampus of Alzheimer’s mice

    Article • Alzheimer s & Dementia, July 2015, Elsevier

    Alexis Bemelmans

  9. 541. Increased Integration of Lentiviral Vector Carrying a D167H Integrase Relies on the Presence of LEDGF/p75

    Article • Molecular Therapy, May 2015, Elsevier

    Alexis Bemelmans

  10. Repair of Rhodopsin mRNA by Spliceosome-Mediated RNA Trans-Splicing: A New Approach for Autosomal Dominant Retinitis Pigmentosa

    Article • Molecular Therapy, May 2015, Elsevier

    Alexis Bemelmans

  11. 495. In Vivo Evidence of trans-Splicing in a Humanized Mouse Model of Autosomal Dominant Retinitis Pigmentosa Induced By Mutation of the Rhodopsin Gene

    Article • Molecular Therapy, May 2015, Elsevier

    Alexis Bemelmans

  12. AMYLOID CASCADE INDUCTION IN AN AAV-BASED MOUSE MODEL OF ALZHEIMER'S DISEASE

    Article • Alzheimer s & Dementia, July 2014, Elsevier

    Professor Nicole Déglon, Alexis Bemelmans

  13. CONSEQUENCES OF APOE2 OVEREXPRESSION IN ASTROCYTES IN AN ALZHEIMER'S DISEASE MOUSE MODEL

    Article • Alzheimer s & Dementia, July 2014, Elsevier

    Alexis Bemelmans

  14. Spectral-Domain Optical Coherence Tomography of the Rodent Eye: Highlighting Layers of the Outer Retina Using Signal Averaging and Comparison with Histology

    Article • PLoS ONE, May 2014, PLOS

    Alexis Bemelmans

  15. 22: EXPERIMENTAL AND CLINICAL OCULAR GENE THERAPY

    Article • January 2014, World Scientific Pub Co Pte Lt

    Alexis Bemelmans

  16. A Single Intravenous AAV9 Injection Mediates Bilateral Gene Transfer to the Adult Mouse Retina

    Article • PLoS ONE, April 2013, PLOS

    Alexis Bemelmans

  17. Taurine Provides Neuroprotection against Retinal Ganglion Cell Degeneration

    Article • PLoS ONE, October 2012, PLOS

    Alexis Bemelmans

  18. Gene Therapy Regenerates Protein Expression in Cone Photoreceptors in Rpe65R91W/R91W Mice

    Article • PLoS ONE, February 2011, PLOS

    Alexis Bemelmans

  19. Remaining Rod Activity Mediates Visual Behavior in AdultRpe65−/−mice.

    Article • Investigative Ophthalmology & Visual Science, December 2010, Association for Research in Vision and Ophthalmology (ARVO)

    Alexis Bemelmans

  20. Lentiviral Gene Transfer-Mediated Cone Vision Restoration in RPE65 Knockout Mice

    Article • January 2008, Springer Science + Business Media

    Alexis Bemelmans

  21. IGF-1 exacerbates the neurotoxicity of the mitochondrial inhibitor 3NP in rats

    Article • Neuroscience Letters, October 2007, Elsevier

    Alexis Bemelmans

  22. Lentiviral Gene Transfer of Rpe65 Rescues Survival and Function of Cones in a Mouse Model of Leber Congenital Amaurosis

    Article • PLoS Medicine, October 2006, PLOS

    Alexis Bemelmans

  23. 419. Rescue of Cone Photoreceptors after Lentiviral Gene Transfer of Rpe65 cDNA in Knockout Mouse Models of Leber Congenital Amaurosis

    Article • Molecular Therapy, January 2006, Elsevier

    Alexis Bemelmans

  24. Functional reinnervation from remaining DA terminals induced by GDNF lentivirus in a rat model of early Parkinson's disease

    Article • Neurobiology of Disease, January 2006, Elsevier

    Alexis Bemelmans

  25. Lentiviral-mediated gene transfer of brain-derived neurotrophic factor is neuroprotective in a mouse model of neonatal excitotoxic challenge

    Article • Journal of Neuroscience Research, January 2006, Wiley

    Alexis Bemelmans

  26. Retinal cell type expression specificity of HIV-1-derived gene transfer vectors upon subretinal injection in the adult rat: influence of pseudotyping and promoter

    Article • The Journal of Gene Medicine, January 2005, Wiley

    Alexis Bemelmans

  27. Insulin growth factor-1 protects against excitotoxicity in the rat striatum

    Article • Neuroreport, October 2004, Wolters Kluwer Health

    Alexis Bemelmans

  28. Brain-Derived Neurotrophic Factor-Mediated Protection of Striatal Neurons in an Excitotoxic Rat Model of Huntington's Disease, as Demonstrated by Adenoviral Gene Transfer

    Article • Human Gene Therapy, December 1999, Mary Ann Liebert Inc

    Alexis Bemelmans

  29. An adenovirus encoding CuZnSOD protects cultured striatal neurones against glutamate toxicity

    Article • Neuroreport, January 1996, Wolters Kluwer Health

    Alexis Bemelmans

  30. Lentiviral Vectors Containing a Retinal Pigment Epithelium Specific Promoter for Leber Congenital Amaurosis Gene Therapy

    Article • Springer Science + Business Media

    Alexis Bemelmans