All Stories

  1. Immunological surveillance against cancer across mammals

    Article • Nature Communications, November 2025, Springer Science + Business Media

    Dr Alexandre Corthay

  2. Deep Multitask Learning for Automated Tissue Segmentation and Cell Detection

    Article • September 2025, Institute of Electrical & Electronics Engineers (IEEE)

    Dr Alexandre Corthay

  3. Statistical analysis of spatial patterns in tumor microenvironment images

    Article • Nature Communications, March 2025, Springer Science + Business Media

    Dr Alexandre Corthay

  4. Abstract 5554: Breast cancer with different chemosensitivity has distinct influence on the immune microenvironment

    Article • Cancer Research, March 2024, American Association for Cancer Research (AACR)

    Dr Alexandre Corthay

  5. Fungal polysaccharides from Inonotus obliquus are agonists for Toll-like receptors and induce macrophage anti-cancer activity

    Article • Communications Biology, February 2024, Springer Science + Business Media

    Dr Alexandre Corthay

  6. On antigen‐specific signals, immune class regulation and energetics: Report III from the workshops on foundational concepts of immune regulation

    Article • Scandinavian Journal of Immunology, July 2023, Wiley

    Dr Alexandre Corthay

  7. Liver-on-chip platform for studying recruitment and differentiation of circulating monocytes

    Article • Journal of Hepatology, June 2023, Elsevier

    Dr Alexandre Corthay

  8. Data from CD4<sup>+</sup> T-cell–Mediated Rejection of MHC Class II–Positive Tumor Cells Is Dependent on Antigen Secretion and Indirect Presentation on Host APCs

    Article • March 2023, American Association for Cancer Research (AACR)

    Dr Alexandre Corthay

  9. Data from CD4<sup>+</sup> T-cell–Mediated Rejection of MHC Class II–Positive Tumor Cells Is Dependent on Antigen Secretion and Indirect Presentation on Host APCs

    Article • March 2023, American Association for Cancer Research (AACR)

    Dr Alexandre Corthay

  10. Supplementary figure S1 from CD4<sup>+</sup> T-cell–Mediated Rejection of MHC Class II–Positive Tumor Cells Is Dependent on Antigen Secretion and Indirect Presentation on Host APCs

    Article • March 2023, American Association for Cancer Research (AACR)

    Dr Alexandre Corthay

  11. Supplementary figure S1 from CD4<sup>+</sup> T-cell–Mediated Rejection of MHC Class II–Positive Tumor Cells Is Dependent on Antigen Secretion and Indirect Presentation on Host APCs

    Article • March 2023, American Association for Cancer Research (AACR)

    Dr Alexandre Corthay

  12. Supplementary figure S2 from CD4<sup>+</sup> T-cell–Mediated Rejection of MHC Class II–Positive Tumor Cells Is Dependent on Antigen Secretion and Indirect Presentation on Host APCs

    Article • March 2023, American Association for Cancer Research (AACR)

    Dr Alexandre Corthay

  13. Supplementary figure S2 from CD4<sup>+</sup> T-cell–Mediated Rejection of MHC Class II–Positive Tumor Cells Is Dependent on Antigen Secretion and Indirect Presentation on Host APCs

    Article • March 2023, American Association for Cancer Research (AACR)

    Dr Alexandre Corthay

  14. Supplementary figure S3 from CD4<sup>+</sup> T-cell–Mediated Rejection of MHC Class II–Positive Tumor Cells Is Dependent on Antigen Secretion and Indirect Presentation on Host APCs

    Article • March 2023, American Association for Cancer Research (AACR)

    Dr Alexandre Corthay

  15. Supplementary figure S3 from CD4<sup>+</sup> T-cell–Mediated Rejection of MHC Class II–Positive Tumor Cells Is Dependent on Antigen Secretion and Indirect Presentation on Host APCs

    Article • March 2023, American Association for Cancer Research (AACR)

    Dr Alexandre Corthay

  16. Supplementary figure S4 from CD4<sup>+</sup> T-cell–Mediated Rejection of MHC Class II–Positive Tumor Cells Is Dependent on Antigen Secretion and Indirect Presentation on Host APCs

    Article • March 2023, American Association for Cancer Research (AACR)

    Dr Alexandre Corthay

  17. Supplementary figure S4 from CD4<sup>+</sup> T-cell–Mediated Rejection of MHC Class II–Positive Tumor Cells Is Dependent on Antigen Secretion and Indirect Presentation on Host APCs

    Article • March 2023, American Association for Cancer Research (AACR)

    Dr Alexandre Corthay

  18. Data from Secretion of Tumor-Specific Antigen by Myeloma Cells Is Required for Cancer Immunosurveillance by CD4<sup>+</sup> T Cells

    Article • March 2023, American Association for Cancer Research (AACR)

    Dr Alexandre Corthay

  19. Data from Secretion of Tumor-Specific Antigen by Myeloma Cells Is Required for Cancer Immunosurveillance by CD4<sup>+</sup> T Cells

    Article • March 2023, American Association for Cancer Research (AACR)

    Dr Alexandre Corthay

  20. Supplementary Table 2 from Secretion of Tumor-Specific Antigen by Myeloma Cells Is Required for Cancer Immunosurveillance by CD4<sup>+</sup> T Cells

    Article • March 2023, American Association for Cancer Research (AACR)

    Dr Alexandre Corthay

  21. Caspase activation counteracts interferon signaling after G2 checkpoint abrogation by ATR inhibition in irradiated human cancer cells

    Article • Frontiers in Oncology, October 2022, Frontiers

    Dr Alexandre Corthay

  22. RNA-sensing pattern-recognition receptors synergize with TLR2 or dectin-1 to trigger high production of IL-12p70 by human dendritic cells

    Article • October 2022, Cold Spring Harbor Laboratory Press

    Dr Alexandre Corthay

  23. OC-0261 ATR inhibition promotes IFN signaling via G2 checkpoint abrogation in irradiated human cancer cells

    Article • Radiotherapy and Oncology, May 2022, Elsevier

    Dr Alexandre Corthay

  24. Immunology according to Dembic: Preserving integrity is key

    Article • Scandinavian Journal of Immunology, April 2022, Wiley

    Dr Alexandre Corthay

  25. Spatial Analysis For Histopathology: A Statistical Approach

    Article • March 2022, Institute of Electrical & Electronics Engineers (IEEE)

    Dr Alexandre Corthay

  26. Tackling cancer cell dormancy: Insights from immune models, and transplantation

    Article • Seminars in Cancer Biology, January 2022, Elsevier

    Dr Alexandre Corthay

  27. Inflammatory Biomarkers for Cancer

    Article • January 2022, Springer Science + Business Media

    Dr Alexandre Corthay

  28. The Immune Landscape of Human Primary Lung Tumors Is Th2 Skewed

    Article • Frontiers in Immunology, November 2021, Frontiers

    Dr Alexandre Corthay

  29. Reactive Species from Two-Signal Activated Macrophages Interfere with Their Oxygen Consumption Measurements

    Article • Antioxidants, July 2021, MDPI AG

    Dr Alexandre Corthay

  30. Obituary: Dr Zoltan A. Nagy (1941–2020)

    Article • Scandinavian Journal of Immunology, February 2021, Wiley

    Dr Alexandre Corthay

  31. Polysaccharides from the fungus Inonotus obliquus activate macrophages into a tumoricidal phenotype via interaction with TLR2, TLR4 and Dectin-1a

    Article • November 2020, Cold Spring Harbor Laboratory Press

    Dr Alexandre Corthay

  32. The immune microenvironment in typical carcinoid lung tumour, a brief report of four cases

    Article • Scandinavian Journal of Immunology, June 2020, Wiley

    Dr Alexandre Corthay

  33. Antibody combinations for optimized staining of macrophages in human lung tumours

    Article • Scandinavian Journal of Immunology, May 2020, Wiley

    Dr Alexandre Corthay

  34. Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models

    Article • Communications Biology, April 2020, Springer Science + Business Media

    Dr Alexandre Corthay

  35. Immune Cell Composition in Human Non-small Cell Lung Cancer

    Article • Frontiers in Immunology, February 2019, Frontiers

    Dr Alexandre Corthay

  36. Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models

    Article • January 2019, Cold Spring Harbor Laboratory Press

    Dr Alexandre Corthay

  37. Both Type I and Type II Interferons Can Activate Antitumor M1 Macrophages When Combined With TLR Stimulation

    Article • Frontiers in Immunology, November 2018, Frontiers

    Dr Alexandre Corthay

  38. CD4+ T cell-mediated rejection of MHC class II-positive tumor cells is dependent on antigen secretion and indirect presentation on host APCs

    Article • Cancer Research, May 2018, American Association for Cancer Research (AACR)

    Dr Alexandre Corthay

  39. Structural characterization of bioactive heteropolysaccharides from the medicinal fungus Inonotus obliquus (Chaga)

    Article • Carbohydrate Polymers, April 2018, Elsevier

    Dr Alexandre Corthay

  40. Aiming for the Insulin-like Growth Factor-1 system in breast cancer therapeutics

    Article • Cancer Treatment Reviews, February 2018, Elsevier

    Dr Alexandre Corthay

  41. Generation and Functional In Vitro Analysis of Semliki Forest Virus Vectors Encoding TNF-α and IFN-γ

    Article • Frontiers in Immunology, November 2017, Frontiers

    Dr Alexandre Corthay

  42. Toll-Like Receptor Ligands and Interferon-γ Synergize for Induction of Antitumor M1 Macrophages

    Article • Frontiers in Immunology, October 2017, Frontiers

    Dr Alexandre Corthay

  43. Poly(I:C)-Encapsulating Nanoparticles Enhance Innate Immune Responses to the Tuberculosis Vaccine Bacille Calmette–Guérin (BCG) via Synergistic Activation of Innate Immune Receptors

    Article • Molecular Pharmaceutics, October 2017, American Chemical Society (ACS)

    Dr Alexandre Corthay

  44. Book Review: The Foundations of Immunology and their Pertinence to Medicine

    Article • Scandinavian Journal of Immunology, July 2017, Wiley

    Dr Alexandre Corthay

  45. Multi-staining registration of large histology images

    Article • April 2017, Institute of Electrical & Electronics Engineers (IEEE)

    Dr Alexandre Corthay

  46. Immune Class Regulation and Its Medical Significance Part II of a Report of a Workshop on Foundational Concepts of Immune Regulation

    Article • Scandinavian Journal of Immunology, March 2017, Wiley

    Dr Alexandre Corthay, Peter Bretscher

  47. Immunological Tolerance. Part I of a Report of a Workshop on Foundational Concepts of Immune Regulation

    Article • Scandinavian Journal of Immunology, February 2017, Wiley

    Dr Alexandre Corthay, Peter Bretscher

  48. Inflammatory Biomarkers for Cancer

    Article • January 2017, Springer Science + Business Media

    Dr Alexandre Corthay

  49. Adoptive Transfer of Tumor-Specific Th2 Cells Eradicates Tumors by Triggering an In Situ Inflammatory Immune Response

    Article • Cancer Research, September 2016, American Association for Cancer Research (AACR)

    Dr Alexandre Corthay

  50. Book Review: Rediscovering the Immune System as an Integrated Organ

    Article • Scandinavian Journal of Immunology, June 2016, Wiley

    Dr Alexandre Corthay

  51. Coupling of HIV-1 Antigen to the Selective Autophagy Receptor SQSTM1/p62 Promotes T-Cell-Mediated Immunity

    Article • Frontiers in Immunology, May 2016, Frontiers

    Dr Alexandre Corthay

  52. Rituximab efficiently depletes B cells in lung tumors and normal lung tissue

    Article • F1000Research, January 2016, Faculty of 1000, Ltd.

    Dr Alexandre Corthay

  53. Interleukin-1 is required for cancer eradication mediated by tumor-specific Th1 cells

    Article • OncoImmunology, July 2015, Taylor & Francis

    Dr Alexandre Corthay

  54. Does the Immune System Naturally Protect Against Cancer?

    Article • Frontiers in Immunology, May 2014, Frontiers

    Dr Alexandre Corthay

  55. How Do CD4+ T Cells Detect and Eliminate Tumor Cells That Either Lack or Express MHC Class II Molecules?

    Article • Frontiers in Immunology, April 2014, Frontiers

    Dr Alexandre Corthay

  56. Molecular profiling of tumor-specific TH1 cells activated in vivo

    Article • OncoImmunology, May 2013, Taylor & Francis

    Dr Alexandre Corthay

  57. SH2D2A Modulates T Cell Mediated Protection to a B Cell Derived Tumor in Transgenic Mice

    Article • PLOS One, October 2012, PLOS

    Dr Alexandre Corthay

  58. A model for cancer-suppressive inflammation

    Article • OncoImmunology, October 2012, Taylor & Francis

    Dr Alexandre Corthay

  59. Fingolimod blocks immunosurveillance of myeloma and B-cell lymphoma resulting in cancer development in mice

    Article • Blood, March 2012, American Society of Hematology

    Dr Alexandre Corthay

  60. CS14-2. A cancer-protective role of inflammation

    Article • Cytokine, October 2011, Elsevier

    Dr Alexandre Corthay

  61. The Matrigel Cytokine Assay

    Article • Protocol Exchange, June 2011, Nature

    Dr Alexandre Corthay

  62. Is Secretion of Tumour-specific Antigen Important for Cancer Eradication by CD4+ T Cells? - Implications for Cancer Immunotherapy by Adoptive T Cell Transfer

    Article • Scandinavian Journal of Immunology, April 2011, Wiley

    Dr Alexandre Corthay

  63. Inflammation driven by tumour-specific Th1 cells protects against B-cell cancer

    Article • Nature Communications, March 2011, Nature

    Dr Alexandre Corthay

  64. How do Regulatory T Cells Work?

    Article • Scandinavian Journal of Immunology, October 2009, Wiley

    Dr Alexandre Corthay

  65. Cytokine profile of successful cancer immunosurveillance mediated by tumor-specific CD4+ T cells

    Article • Cytokine, October 2009, Elsevier

    Dr Alexandre Corthay

  66. Secretion of Tumor-Specific Antigen by Myeloma Cells Is Required for Cancer Immunosurveillance by CD4+ T Cells

    Article • Cancer Research, June 2009, American Association for Cancer Research (AACR)

    Dr Alexandre Corthay

  67. Isoform-specific regulation of immune cell reactivity by the catalytic subunit of protein kinase A (PKA)

    Article • Cellular Signalling, February 2009, Elsevier

    Dr Alexandre Corthay

  68. A Three-cell Model for Activation of Naïve T Helper Cells

    Article • Scandinavian Journal of Immunology, August 2006, Wiley

    Dr Alexandre Corthay

  69. Systemic Autoimmune Disease Caused by Autoreactive B Cells That Receive Chronic Help from Ig V Region-Specific T Cells

    Article • The Journal of Immunology, August 2005, The American Association of Immunologists

    Dr Alexandre Corthay

  70. Primary Antitumor Immune Response Mediated by CD4+ T Cells

    Article • Immunity, March 2005, Elsevier

    Egil Røsjø, Dr Alexandre Corthay

  71. Immunotherapy in multiple myeloma: Id-specific strategies suggested by studies in animal models

    Article • Medical Oncology, April 2004, Springer Science + Business Media

    Dr Alexandre Corthay

  72. Monoclonal Antibodies Produced by Muscle after Plasmid Injection and Electroporation

    Article • Molecular Therapy, March 2004, Elsevier

    Dr Alexandre Corthay

  73. Role of gamma/delta T cell receptor-expressing lymphocytes in cutaneous infection caused by Staphylococcus aureus

    Article • Clinical & Experimental Immunology, May 2003, Wiley

    Dr Alexandre Corthay

  74. Therapeutic effect of idiotype-specific CD4+ T cells against B-cell lymphoma in the absence of anti-idiotypic antibodies

    Article • Blood, March 2003, American Society of Hematology

    Dr Alexandre Corthay

  75. Evaluation of the Percentage of Peripheral T Cells with Two Different T Cell Receptor α-Chains and of their Potential Role in Autoimmunity

    Article • Journal of Autoimmunity, June 2001, Elsevier

    Docent Kutty Selva Nandakumar, Dr Alexandre Corthay

  76. Role of glycopeptide-specific T cells in collagen-induced arthritis: an example how Dost-translational modification of proteins Gay be involved in autoimmune disease

    Article • Annals of Medicine, January 2001, Taylor & Francis

    Dr Alexandre Corthay

  77. T lymphocytes are not required for the spontaneous development of entheseal ossification leading to marginal ankylosis in the DBA/1 mouse

    Article • Arthritis & Rheumatism, April 2000, Wiley

    Dr Alexandre Corthay

  78. Collagen-induced arthritis development requires alphabeta T cells but not gammadelta T cells: studies with T cell-deficient (TCR mutant) mice

    Article • International Immunology, July 1999, Oxford University Press (OUP)

    Dr Alexandre Corthay

  79. Epitope glycosylation plays a critical role for T cell recognition of type II collagen in collagen-induced arthritis

    Article • European Journal of Immunology, August 1998, Wiley

    Dr Alexandre Corthay

  80. CD4+ T Cells Cooperate With Macrophages for Specific Elimination of MHC Class II-Negative Cancer Cells

    Article • Springer Science + Business Media

    Dr Alexandre Corthay