All Stories

  1. Opioids and the Kidney: A Compendium
  2. Repeated seizures lead to progressive ventilatory dysfunction in SSKcnj16−/− rats
  3. Kir7.1 knockdown and inhibition alter renal electrolyte handling but not the development of hypertension in Dahl salt-sensitive rats
  4. Call for Papers: podocyte physiology and pathophysiology
  5. The circadian clock protein PER1 is important in maintaining endothelin axis regulation in Dahl salt-sensitive rats
  6. Ion channels and channelopathies in glomeruli
  7. Modulation of P2X 4 receptor activity by ivermectin and 5‐BDBD has no effect on the development of ARPKD ...
  8. Kir5.1 channels: potential role in epilepsy and seizure disorders
  9. Modulation of blood pressure regulatory genes in the Agtrap‐Plod1 locus associated with a deletion in Clcn6
  10. SGLT2 inhibition effect on salt-induced hypertension, RAAS, and Na+ transport in Dahl SS rats
  11. Astrocytic responses to high glucose impair barrier formation in cerebral microvessel endothelial cells
  12. Epac1–/– and Epac2–/– mice exhibit deficient epithelial Na+ channel regulation and impaired urinary Na+ conservation
  13. Crosstalk between epithelial sodium channels (ENaC) and basolateral potassium channels (Kir4.1/Kir5.1) in the cortical collecting duct
  14. Characterization of purinergic receptor 2 signaling in podocytes from diabetic kidneys
  15. Cytoskeleton Rearrangements Modulate TRPC6 Channel Activity in Podocytes
  16. Scanning ion conductance microscopy of live human glomerulus
  17. Loss of Chloride Channel 6 (CLC-6) Affects Vascular Smooth Muscle Contractility and Arterial Stiffness via Alterations to Golgi Calcium Stores
  18. Kcnj16 knockout produces audiogenic seizures in the Dahl salt-sensitive rat
  19. American Journal of Physiology-Renal Physiology Collections: Hypertension
  20. Behavioral, metabolic, and renal outcomes of 1-month isolation in adolescent male Dahl salt-sensitive rats
  21. O’Brien Kidney Research Centers
  22. SGLT2 inhibitors: diabetic kidney disease and beyond
  23. Role of opioid signaling in kidney damage during the development of salt-induced hypertension
  24. NOX4‐dependent regulation of ENaC in hypertension and diabetic kidney disease
  25. Effects of uric acid dysregulation on the kidney
  26. Expression, localization, and functional properties of inwardly rectifying K+channels in the kidney
  27. Metabolic rewiring of the hypertensive kidney
  28. Postprandial effects on electrolyte homeostasis in the kidney
  29. Relationship between the renin–angiotensin–aldosterone system and renal Kir5.1 channels
  30. Vibrodissociation method for isolation of defined nephron segments from human and rodent kidneys
  31. Increased ENaC activity during kidney preservation in Wisconsin solution
  32. The importance of the pH-sensitive Kir5.1 channel in short-term and long-term regulation of pH
  33. Postprandial Effects on ENaC-Mediated Sodium Absorption
  34. Salt-deficient diet exacerbates cystogenesis in ARPKD via epithelial sodium channel (ENaC)
  35. Visualization and Quantification of Mitochondrial Structure in the Endothelium of Intact Arteries
  36. Characterization of purinergic receptor expression in ARPKD cystic epithelia
  37. Endothelin receptor A and p66Shc regulate spontaneous Ca2+oscillations in smooth muscle cells controlling renal arterial spontaneous motion
  38. Protective role of Trpc6 knockout in the progression of diabetic kidney disease
  39. Distal tubule basolateral potassium channels
  40. Inactivation of p66Shc Decreases Afferent Arteriolar KATP Channel Activity and Decreases Renal Damage in Diabetic Dahl SS Rats
  41. A mutation affecting polycystin-1 mediated heterotrimeric G-protein signaling causes PKD
  42. Region-Based Convolutional Neural Nets for Localization of Glomeruli in Trichrome-Stained Whole Kidney Sections
  43. β1Pix exchange factor stabilizes the ubiquitin ligase Nedd4-2 and plays a critical role in ENaC regulation by AMPK in kidney epithelial cells
  44. Beneficial Effects of High Potassium
  45. A NOX4/TRPC6 Pathway in Podocyte Calcium Regulation and Renal Damage in Diabetic Kidney Disease
  46. Role of adaptor protein p66Shc in renal pathologies
  47. Nitric oxide production by glomerular podocytes
  48. Essential role of Kir5.1 channels in renal salt handling and blood pressure control
  49. Acute In Vivo Analysis of ATP Release in Rat Kidneys in Response to Changes of Renal Perfusion Pressure
  50. Intravital imaging of the kidney in a rat model of salt-sensitive hypertension
  51. Involvement of ENaC in the development of salt-sensitive hypertension
  52. The normal increase in insulin after a meal may be required to prevent postprandial renal sodium and volume losses
  53. Lack of Effects of Metformin and AICAR Chronic Infusion on the Development of Hypertension in Dahl Salt-Sensitive Rats
  54. Hypertension and Diabetes Mellitus
  55. The Role of Angiotensin II in Glomerular Volume Dynamics and Podocyte Calcium Handling
  56. Functional and therapeutic importance of purinergic signaling in polycystic kidney disease
  57. Protease-activated receptors in kidney disease progression
  58. The function of SH2B3 (LNK) in the kidney
  59. High salt diet and caffeine: food for thought
  60. Chronic cathepsin inhibition by E-64 in Dahl salt-sensitive rats
  61. Regulation of Polycystin-1 Function by Calmodulin Binding
  62. Two-photon imaging of endothelin-1-mediated intracellular Ca 2+ handling in smooth muscle cells of rat renal resistance arteries
  63. Renal channels and transporters in Renin KO rats
  64. p66Shc regulates renal vascular tone in hypertension-induced nephropathy
  65. Role and mechanisms of regulation of the basolateral Kir4.1/Kir5.1K+channels in the distal tubules
  66. Mechanosensory and ATP Release Deficits following Keratin14-Cre-Mediated TRPA1 Deletion Despite Absence of TRPA1 in Murine Keratinocytes
  67. Insulin and IGF-1 activate Kir4.1/5.1 channels in cortical collecting duct principal cells to control basolateral membrane voltage
  68. Fundamentals of Epithelial Na+ Absorption
  69. Evidence of the Importance of Nox4 in Production of Hypertension in Dahl Salt-Sensitive Rats
  70. Podocyte injury in diabetic nephropathy: implications of angiotensin II – dependent activation of TRPC channels
  71. Use of Enzymatic Biosensors to Quantify Endogenous ATP or H2O2 in the Kidney
  72. TRPC6 channel as an emerging determinant of the podocyte injury susceptibility in kidney diseases
  73. Implementing Patch Clamp and Live Fluorescence Microscopy to Monitor Functional Properties of Freshly Isolated PKD Epithelium
  74. Single-channel Analysis and Calcium Imaging in the Podocytes of the Freshly Isolated Glomeruli
  75. Two-photon Imaging of Intracellular Ca2+ Handling and Nitric Oxide Production in Endothelial and Smooth Muscle Cells of an Isolated Rat Aorta
  76. Cross-talk between insulin and IGF-1 receptors in the cortical collecting duct principal cells: implication for ENaC-mediated Na+ reabsorption
  77. Acetylation Stimulates the Epithelial Sodium Channel by Reducing Its Ubiquitination and Degradation
  78. Inhibition of ENaC by Endothelin-1
  79. Impaired epithelial Na+ channel activity contributes to cystogenesis and development of autosomal recessive polycystic kidney disease in PCK rats
  80. Epoxyeicosatrienoic acid analogue lowers blood pressure through vasodilation and sodium channel inhibition
  81. To cleave or not to cleave: role of ADAM17 in cell proliferation in PKD
  82. Angiotensin II has acute effects on TRPC6 channels in podocytes of freshly isolated glomeruli
  83. Role of Rho GDP Dissociation Inhibitor α in Control of Epithelial Sodium Channel (ENaC)-mediated Sodium Reabsorption
  84. Mutation of Plekha7 attenuates salt-sensitive hypertension in the rat
  85. PC and PKC: in vivo vs. in vitro
  86. Pharmacological characterization of the P2 receptors profile in the podocytes of the freshly isolated rat glomeruli
  87. Direct inhibition of basolateral Kir4.1/5.1 and Kir4.1 channels in the cortical collecting duct by dopamine
  88. Aldosterone-dependent trans-activation and epigenetic derepression of ENaC: where is the balance?
  89. Arp2/3 complex inhibitors adversely affect actin cytoskeleton remodeling in the cultured murine kidney collecting duct M-1 cells
  90. Orally Active Epoxyeicosatrienoic Acid Analog Attenuates Kidney Injury in Hypertensive Dahl Salt-Sensitive Rat
  91. Detection of endogenous substances with enzymatic microelectrode biosensors in the kidney
  92. Epidermal growth factors in the kidney and relationship to hypertension
  93. Real-time electrochemical detection of ATP and H2O2 release in freshly isolated kidneys
  94. Deficiency of Renal Cortical EGF Increases ENaC Activity and Contributes to Salt-Sensitive Hypertension
  95. Regulation of ENaC in mice lacking renal insulin receptors in the collecting duct
  96. ROS production as a common mechanism of ENaC regulation by EGF, insulin, and IGF-1
  97. Recording Ion Channels in Isolated, Split-Opened Tubules
  98. Single-Channel Analysis of TRPC Channels in the Podocytes of Freshly Isolated Glomeruli
  99. G-protein signaling modulator 1 deficiency accelerates cystic disease in an orthologous mouse model of autosomal dominant polycystic kidney disease
  100. Direct Activation of ENaC by Angiotensin II: Recent Advances and New Insights
  101. Regulation of TRPC6 channels by non-steroidal anti-inflammatory drugs
  102. Ion transport in the connecting tubule and cortical collecting duct
  103. Mechanisms of epithelial sodium channel (ENaC) regulation by cortactin: Involvement of dynamin
  104. Role of βPix in the Kidney
  105. Angiotensin II Increases Activity of the Epithelial Na+Channel (ENaC) in Distal Nephron Additively to Aldosterone
  106. Epidermal growth factor-mediated proliferation and sodium transport in normal and PKD epithelial cells
  107. Effects of cytochrome P-450 metabolites of arachidonic acid on the epithelial sodium channel (ENaC)
  108. Cortical actin binding protein cortactin mediates ENaC activity via Arp2/3 complex
  109. NSAIDs acutely inhibit TRPC channels in freshly isolated rat glomeruli
  110. Novel Role of Rac1/WAVE Signaling Mechanism in Regulation of the Epithelial Na+ Channel
  111. Endothelin-1 Inhibits the Epithelial Na+ Channel through  Pix/14-3-3/Nedd4-2
  112. Contribution of TRPV1-TRPA1 Interaction to the Single Channel Properties of the TRPA1 Channel
  113. Intact Cytoskeleton Is Required for Small G Protein Dependent Activation of the Epithelial Na+ Channel
  114. Regulation of ENaC-Mediated Sodium Reabsorption by Peroxisome Proliferator-Activated Receptors
  115. The actin cytoskeleton and small G protein RhoA are not involved in flow-dependent activation of ENaC
  116. Muscarinic M1 modulation of acid-sensing ion channels
  117. Peroxisome Proliferator-Activated Receptor γ Antagonists Decrease Na+ Transport via the Epithelial Na+ Channel
  118. Regulation of the epithelial sodium channels (ENaC) by small G proteins and phosphatidylinositides
  119. Intrinsic Voltage Dependence of the Epithelial Na+Channel Is Masked by a Conserved Transmembrane Domain Tryptophan
  120. EGF and its related growth factors mediate sodium transport in mpkCCDc14cells via ErbB2 (neu/HER-2) receptor
  121. Regulation of ENaC expression at the cell surface by Rab11
  122. Insight toward epithelial Na+channel mechanism revealed by the acid-sensing ion channel 1 structure
  123. Mechanisms of non-steroid anti-inflammatory drugs action on ASICs expressed in hippocampal interneurons
  124. Ion Channel Regulation by Ras, Rho, and Rab Small GTPases
  125. Molecular Determinants of PI(4,5)P2and PI(3,4,5)P3Regulation of the Epithelial Na+Channel
  126. Acute Regulation of the Epithelial Na+ Channel by Phosphatidylinositide 3-OH Kinase Signaling in Native Collecting Duct Principal Cells
  127. Binding and direct activation of the epithelial Na+channel (ENaC) by phosphatidylinositides
  128. Quantifying RhoA Facilitated Trafficking of the Epithelial Na+Channel toward the Plasma Membrane with Total Internal Reflection Fluorescence-Fluorescence Recovery after Photobleaching
  129. Magnesium permeation through mechanosensitive channels: single-current measurements
  130. Rapid Translocation and Insertion of the Epithelial Na+Channel in Response to RhoA Signaling
  131. Regulation of the epithelial Na+ channel (ENaC) by phosphatidylinositides
  132. Subunit-dependent cadmium and nickel inhibition of acid-sensing ion channels
  133. Regulation of Epithelial Na+Channel Activity by Conserved Serine/Threonine Switches within Sorting Signals
  134. Identification of a Functional Phosphatidylinositol 3,4,5-Trisphosphate Binding Site in the Epithelial Na+Channel
  135. ENaC stoichiometry
  136. Actin cytoskeleton disassembly affects conductive properties of stretch-activated cation channels in leukaemia cells
  137. Ras couples phosphoinositide 3-OH kinase to the epithelial Na+ channel
  138. Rho Small GTPases Activate the Epithelial Na+Channel
  139. Ras Activates the Epithelial Na+Channel through Phosphoinositide 3-OH Kinase Signaling
  140. Fluorescence Resonance Energy Transfer Analysis of Subunit Stoichiometry of the Epithelial Na+Channel
  141. Mechanosensitive cation channels in human leukaemia cells: calcium permeation and blocking effect
  142. Giant multimodal heart motoneurons of Achatina fulica: a new cardioregulatory input in pulmonates