All Stories

  1. Calmodulin: A Multitasking Protein in Kv7.2 Potassium Channel Functions

    Article • Biomolecules, July 2018, MDPI AG

    ALESSANDRO ALAIMO

  2. Lack of correlation between surface expression and currents in epileptogenic AB-calmodulin binding domain Kv7.2 potassium channel mutants

    Article • Channels, January 2018, Taylor & Francis

    ALESSANDRO ALAIMO

  3. Calmodulin confers calcium sensitivity to the stability of the distal intracellular assembly domain of Kv7.2 channels

    Article • Scientific Reports, October 2017, Springer Science + Business Media

    ALESSANDRO ALAIMO

  4. Early-onset epileptic encephalopathy caused by a reduced sensitivity of Kv7.2 potassium channels to phosphatidylinositol 4,5-bisphosphate

    Article • Scientific Reports, December 2016, Springer Science + Business Media

    ALESSANDRO ALAIMO

  5. Uncoupling PIP2-calmodulin regulation of Kv7.2 channels by an assembly destabilizing epileptogenic mutation

    Article • Journal of Cell Science, September 2015, The Company of Biologists

    ALESSANDRO ALAIMO

  6. Epilepsy-causing mutations in Kv7.2 C-terminus affect binding and functional modulation by calmodulin

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, September 2015, Elsevier

    ALESSANDRO ALAIMO

  7. An unconventional calmodulin-anchoring site within the AB module of Kv7.2 channels

    Article • Journal of Cell Science, July 2015, The Company of Biologists

    ALESSANDRO ALAIMO

  8. The Ever Changing Moods of Calmodulin: How Structural Plasticity Entails Transductional Adaptability

    Article • Journal of Molecular Biology, July 2014, Elsevier

    Jon Agirre, ALESSANDRO ALAIMO, Maurizio Taglialatela

  9. Pivoting between Calmodulin Lobes Triggered by Calcium in the Kv7.2/Calmodulin Complex

    Article • PLoS ONE, January 2014, PLOS

    ALESSANDRO ALAIMO

  10. Clicked bis-PEG-peptide conjugates for studying calmodulin-Kv7.2 channel binding

    Article • Organic & Biomolecular Chemistry, January 2014, Royal Society of Chemistry

    ALESSANDRO ALAIMO

  11. Pivoting between Calmodulin Lobes in the Calmodulin/Kv7.2 Complex Triggered by Calcium

    Article • Biophysical Journal, January 2013, Elsevier

    ALESSANDRO ALAIMO

  12. The Use of Dansyl-Calmodulin to Study Interactions with Channels and Other Proteins

    Article • January 2013, Springer Science + Business Media

    ALESSANDRO ALAIMO

  13. Cooperativity between calmodulin-binding sites in Kv7.2 channels

    Article • Journal of Cell Science, November 2012, The Company of Biologists

    ALESSANDRO ALAIMO

  14. Surface Expression and Subunit Specific Control of Steady Protein Levels by the Kv7.2 Helix A-B Linker

    Article • PLoS ONE, October 2012, PLOS

    ALESSANDRO ALAIMO

  15. Calmodulin Independent Trafficking of Kv7.2 Channels

    Article • Biophysical Journal, February 2011, Elsevier

    ALESSANDRO ALAIMO

  16. Anomalous Calcium Dependent Binding of Calmodulin to KCNQ2 Potassium Channels

    Article • Biophysical Journal, January 2010, Elsevier

    ALESSANDRO ALAIMO

  17. Selective Interaction of Syntaxin 1A with KCNQ2: Possible Implications for Specific Modulation of Presynaptic Activity

    Article • PLoS ONE, August 2009, PLOS

    ALESSANDRO ALAIMO

  18. Calmodulin Activation Limits the Rate of KCNQ2 K+Channel Exit from the Endoplasmic Reticulum

    Article • Journal of Biological Chemistry, June 2009, American Society for Biochemistry & Molecular Biology (ASBMB)

    ALESSANDRO ALAIMO

  19. Calmodulin regulates the trafficking of KCNQ2 potassium channels

    Article • The FASEB Journal, November 2007, Federation of American Societies For Experimental Biology (FASEB)

    ALESSANDRO ALAIMO