All Stories

  1. Investigation of H2AX methylation by the SUV39H2 protein lysine methyltransferase

    Article • FEBS Letters, May 2016, Wiley

    Professor Albert Jeltsch

  2. Quality of histone modification antibodies undermines chromatin biology research

    Article • F1000Research, October 2015, Faculty of 1000, Ltd.

    Professor Albert Jeltsch

  3. New concepts in DNA methylation

    Article • Trends in Biochemical Sciences, July 2014, Elsevier

    Professor Albert Jeltsch

  4. Targeted Mutagenesis Results in an Activation of DNA Methyltransferase 1 and Confirms an Autoinhibitory Role of its RFTS Domain

    Article • ChemBioChem, February 2014, Wiley

    Professor Albert Jeltsch

  5. Substrate Specificity Analysis and Novel Substrates of the Protein Lysine Methyltransferase NSD1

    Article • Chemistry & Biology, February 2014, Elsevier

    Professor Albert Jeltsch

  6. Targeted Methylation of the Epithelial Cell Adhesion Molecule (EpCAM) Promoter to Silence Its Expression in Ovarian Cancer Cells

    Article • PLoS ONE, January 2014, PLOS

    Professor Albert Jeltsch

  7. Genomic Imprinting – der Kampf der Geschlechter auf molekularer Ebene

    Article • Angewandte Chemie, November 2013, Wiley

    Professor Albert Jeltsch

  8. Genomic Imprinting—The Struggle of the Genders at the Molecular Level

    Article • Angewandte Chemie International Edition, November 2013, Wiley

    Professor Albert Jeltsch

  9. Non‐radioactive Protein Lysine Methyltransferase Microplate Assay Based on Reading Domains

    Article • ChemMedChem, May 2013, Wiley

    Professor Albert Jeltsch

  10. Oxygen, epigenetic signaling, and the evolution of early life

    Article • Trends in Biochemical Sciences, April 2013, Elsevier

    Professor Albert Jeltsch

  11. Targeted Methylation and Gene Silencing of VEGF-A in Human Cells by Using a Designed Dnmt3a–Dnmt3L Single-Chain Fusion Protein with Increased DNA Methylation Activity

    Article • Journal of Molecular Biology, February 2013, Elsevier

    Professor Albert Jeltsch

  12. Multimerization of the Dnmt3a DNA Methyltransferase and Its Functional Implications

    Article • January 2013, Elsevier

    Professor Albert Jeltsch

  13. The SET8 H4K20 protein lysine methyltransferase has a long recognition sequence covering seven amino acid residues

    Article • Biochimie, November 2012, Elsevier

    Professor Albert Jeltsch

  14. DNA methyltransferase inhibitors in cancer: a chemical and therapeutic patent overview and selected clinical studies

    Article • Expert Opinion on Therapeutic Patents, October 2012, Informa Healthcare

    Professor Albert Jeltsch

  15. Identification of ICAD‐derived peptides capable of inhibiting caspase‐activated DNase

    Article • FEBS Journal, July 2012, Wiley

    Professor Albert Jeltsch

  16. Mechanistic details of the DNA recognition by the Dnmt1 DNA methyltransferase

    Article • FEBS Letters, May 2012, Wiley

    Professor Albert Jeltsch

  17. DNA Interaction of the CcrM DNA Methyltransferase: A Mutational and Modeling Study

    Article • ChemBioChem, May 2012, Wiley

    Professor Albert Jeltsch, Professor Martin Zacharias

  18. Specificity of Dnmt1 for Methylation of Hemimethylated CpG Sites Resides in Its Catalytic Domain

    Article • Chemistry & Biology, May 2012, Elsevier

    Professor Albert Jeltsch

  19. Conference Scene: Epigenetics Europe 2011

    Article • Epigenomics, December 2011, Future Medicine

    Professor Albert Jeltsch

  20. On the Evolutionary Origin of Eukaryotic DNA Methyltransferases and Dnmt2

    Article • PLoS ONE, November 2011, PLOS

    Professor Albert Jeltsch

  21. Burning off DNA Methylation: New Evidence for Oxygen‐Dependent DNA Demethylation

    Article • ChemBioChem, October 2011, Wiley

    Professor Albert Jeltsch

  22. Auto‐methylation of the mouse DNA‐(cytosine C5)‐methyltransferase Dnmt3a at its active site cysteine residue

    Article • FEBS Journal, May 2011, Wiley

    Professor Albert Jeltsch

  23. The inhibition of the mammalian DNA methyltransferase 3a (Dnmt3a) by dietary black tea and coffee polyphenols

    Article • BMC Biochemistry, April 2011, Springer Science + Business Media

    Professor Albert Jeltsch

  24. Approaches to Enzyme and Substrate Design of the Murine Dnmt3a DNA Methyltransferase

    Article • ChemBioChem, March 2011, Wiley

    Professor Albert Jeltsch

  25. Handbook of Epigenetics: The New Molecular and Medical Genetics. Edited by Trygve Tollefsbol.

    Article • ChemBioChem, February 2011, Wiley

    Professor Albert Jeltsch

  26. Detailed specificity analysis of antibodies binding to modified histone tails with peptide arrays

    Article • Epigenetics, February 2011, Taylor & Francis

    Professor Albert Jeltsch

  27. Editorial: Molecular Epigenetics: Connecting Human Biology and Disease with Little Marks

    Article • ChemBioChem, January 2011, Wiley

    Professor Albert Jeltsch

  28. DNA Methyltransferase Assays

    Article • January 2011, Springer Science + Business Media

    Professor Albert Jeltsch

  29. Specificity Analysis-Based Identification of New Methylation Targets of the SET7/9 Protein Lysine Methyltransferase

    Article • Chemistry & Biology, January 2011, Elsevier

    Professor Albert Jeltsch

  30. Structure and Function of Mammalian DNA Methyltransferases

    Article • ChemBioChem, November 2010, Wiley

    Professor Albert Jeltsch

  31. The Application of Next Generation Sequencing in DNA Methylation Analysis

    Article • Genes, June 2010, MDPI AG

    Professor Albert Jeltsch

  32. BISMA - Fast and accurate bisulfite sequencing data analysis of individual clones from unique and repetitive sequences

    Article • BMC Bioinformatics, May 2010, Springer Science + Business Media

    Professor Albert Jeltsch

  33. Silencing of Gene Expression by Targeted DNA Methylation: Concepts and Approaches

    Article • January 2010, Springer Science + Business Media

    Professor Albert Jeltsch

  34. Non-imprinted allele-specific DNA methylation on human autosomes

    Article • December 2009, Springer Science + Business Media

    Professor Albert Jeltsch

  35. Epigenetic Targets in Drug Discovery. Edited by Wolfgang Sippl and Manfred Jung.

    Article • ChemBioChem, November 2009, Wiley

    Professor Albert Jeltsch

  36. Transition from EcoDam to T4Dam DNA Recognition Mechanism without Loss of Activity and Specificity

    Article • ChemBioChem, October 2009, Wiley

    Professor Albert Jeltsch

  37. New clustering module in BDPC bisulfite sequencing data presentation and compilation web application for DNA methylation analyses

    Article • BioTechniques, September 2009, Future Science

    Professor Albert Jeltsch

  38. Impact of 7,8-Dihydro-8-oxoguanine on Methylation of the CpG Site by Dnmt3a

    Article • Biochemistry, January 2009, American Chemical Society (ACS)

    Professor Albert Jeltsch

  39. DNA Methylation Analysis by Bisulfite Conversion, Cloning, and Sequencing of Individual Clones

    Article • January 2009, Springer Science + Business Media

    Professor Albert Jeltsch

  40. Reading and writing DNA methylation

    Article • Nature Structural & Molecular Biology, October 2008, Springer Science + Business Media

    Professor Albert Jeltsch

  41. Putting the Pieces Together: Histone H2B Ubiquitylation Directly Stimulates Histone H3K79 Methylation

    Article • ChemBioChem, September 2008, Wiley

    Professor Albert Jeltsch

  42. Design of Restriction Endonucleases with Novel Specificity

    Article • March 2008, Wiley

    Professor Albert Jeltsch

  43. Analysis of the Substrate Specificity of the Dim-5 Histone Lysine Methyltransferase Using Peptide Arrays

    Article • Chemistry & Biology, January 2008, Elsevier

    Professor Albert Jeltsch

  44. Specificity of protein lysine methyltransferases and methods for detection of lysine methylation of non-histone proteins

    Article • Molecular BioSystems, January 2008, Royal Society of Chemistry

    Professor Albert Jeltsch

  45. Continuous enzymatic assay for histone lysine methyltransferases

    Article • BioTechniques, November 2007, Future Science

    Professor Albert Jeltsch

  46. Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation

    Article • Nature, August 2007, Springer Science + Business Media

    Professor Albert Jeltsch

  47. Phosphorylation of Serine-515 Activates the Mammalian Maintenance Methyltransferase Dnmt1

    Article • Epigenetics, July 2007, Taylor & Francis

    Professor Albert Jeltsch

  48. Application of DNA methyltransferases in targeted DNA methylation

    Article • Applied Microbiology and Biotechnology, April 2007, Springer Science + Business Media

    Professor Albert Jeltsch

  49. Reversible Inactivation of the CG Specific SssI DNA (Cytosine‐C5)‐Methyltransferase with a Photocleavable Protecting Group

    Article • ChemBioChem, January 2007, Wiley

    Professor Albert Jeltsch

  50. Quantitative Analysis of Biochemical Data

    Article • September 2006, Wiley

    Professor Albert Jeltsch

  51. Restriction Endonuclease and DNA-Modification Methyltransferases

    Article • September 2006, Wiley

    Professor Albert Jeltsch

  52. Two substrates are better than one: dual specificities for Dnmt2 methyltransferases

    Article • Trends in Biochemical Sciences, June 2006, Elsevier

    Professor Albert Jeltsch

  53. Structure and Substrate Recognition of the Escherichia coli DNA Adenine Methyltransferase

    Article • Journal of Molecular Biology, April 2006, Elsevier

    Professor Albert Jeltsch

  54. De Novo Methylation of Nucleosomal DNA by the Mammalian Dnmt1 and Dnmt3A DNA Methyltransferases

    Article • Biochemistry, June 2005, American Chemical Society (ACS)

    Professor Albert Jeltsch

  55. Profound Flanking Sequence Preference of Dnmt3a and Dnmt3b Mammalian DNA Methyltransferases Shape the Human Epigenome

    Article • Journal of Molecular Biology, May 2005, Elsevier

    Professor Albert Jeltsch

  56. Transition from Nonspecific to Specific DNA Interactions along the Substrate-Recognition Pathway of Dam Methyltransferase

    Article • Cell, May 2005, Elsevier

    Professor Albert Jeltsch

  57. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy

    Article • Cancer Biology & Therapy, November 2004, Taylor & Francis

    Professor Albert Jeltsch

  58. Anomalous mobility of polymerase chain reaction products after bisulfite treatment of DNA

    Article • Analytical Biochemistry, October 2004, Elsevier

    Professor Albert Jeltsch

  59. Stopped-flow and Mutational Analysis of Base Flipping by the Escherichia coli Dam DNA-(adenine-N6)-methyltransferase

    Article • Journal of Molecular Biology, August 2004, Elsevier

    Professor Albert Jeltsch

  60. DNA Methyltransferases, Bacterial

    Article • January 2004, Elsevier

    Professor Albert Jeltsch

  61. Maintenance of species identity and controlling speciation of bacteria: a new function for restriction/modification systems?

    Article • Gene, October 2003, Elsevier

    Professor Albert Jeltsch

  62. Detection and analysis of enzymatic DNA methylation of oligonucleotide substrates by matrix-assisted laser desorption ionization time-of-flight mass spectrometry

    Article • Analytical Biochemistry, February 2003, Elsevier

    Professor Albert Jeltsch

  63. Probing the DNA Interface of the EcoRV DNA-(Adenine-N6)-methyltransferase by Site-Directed Mutagenesis, Fluorescence Spectroscopy, and UV Cross-Linking

    Article • Biochemistry, November 2002, American Chemical Society (ACS)

    Professor Albert Jeltsch

  64. Dnmt3a and Dnmt1 functionally cooperate during de novo methylation of DNA

    Article • European Journal of Biochemistry, October 2002, Wiley

    Professor Albert Jeltsch

  65. A fluorimetric assay for on-line detection of DNA cleavage by restriction endonucleases

    Article • Journal of Biotechnology, June 2002, Elsevier

    Professor Albert Jeltsch

  66. Beyond Watson and Crick: DNA Methylation and Molecular Enzymology of DNA Methyltransferases

    Article • ChemBioChem, May 2002, Wiley

    Professor Albert Jeltsch

  67. Beyond Watson and Crick: DNA Methylation and Molecular Enzymology of DNA Methyltransferases

    Article • ChemBioChem, April 2002, Wiley

    Professor Albert Jeltsch

  68. Site-Directed Mutagenesis by Polymerase Chain Reaction

    Article • January 2002, Springer Science + Business Media

    Professor Albert Jeltsch

  69. DNA from Aspergillus flavus contains 5-methylcytosine

    Article • FEMS Microbiology Letters, November 2001, Oxford University Press (OUP)

    Professor Albert Jeltsch

  70. Enzymes that keep DNA under control

    Article • EMBO Reports, April 2001, EMBO

    Professor Albert Jeltsch

  71. The Cytosine N4-Methyltransferase M.PvuII Also Modifies Adenine Residues

    Article • Biological Chemistry, January 2001, De Gruyter

    Professor Albert Jeltsch

  72. Biotin-Avidin Microplate Assay for the Quantitative Analysis of Enzymatic Methylation of DNA by DNA Methyltransferases

    Article • Biological Chemistry, January 2000, De Gruyter

    Professor Albert Jeltsch

  73. Circular Permutations in the Molecular Evolution of DNA Methyltransferases

    Article • Journal of Molecular Evolution, July 1999, Springer Science + Business Media

    Professor Albert Jeltsch

  74. Plasmid DNA Cleavage by MunI Restriction Enzyme:  Single-Turnover and Steady-State Kinetic Analysis

    Article • Biochemistry, March 1999, American Chemical Society (ACS)

    Professor Albert Jeltsch

  75. Mutational Analysis of Target Base Flipping by the EcoRV Adenine-N6 DNA Methyltransferase

    Article • Journal of Molecular Biology, January 1999, Elsevier

    Professor Albert Jeltsch

  76. Flexibility of DNA in complex with proteins deduced from the distribution of bending angles observed by scanning force microscopy

    Article • Biophysical Chemistry, August 1998, Elsevier

    Professor Albert Jeltsch

  77. Kinetic Characterization of Linear Diffusion of the Restriction Endonuclease EcoRV on DNA

    Article • Biochemistry, February 1998, American Chemical Society (ACS)

    Professor Albert Jeltsch

  78. Kinetics of methylation and binding of DNA by the Eco RV adenine-N 6 methyltransferase 1 1Edited by J Karn

    Article • Journal of Molecular Biology, February 1998, Elsevier

    Professor Albert Jeltsch

  79. Functional Mapping of the EcoRV DNA Methyltransferase by Random Mutagenesis and Screening for Catalytically Inactive Mutants

    Article • Biological Chemistry, January 1998, De Gruyter

    Professor Albert Jeltsch

  80. Does the Restriction Endonuclease EcoRV Employ a Two-Metal-Ion Mechanism for DNA Cleavage?

    Article • Biochemistry, September 1997, American Chemical Society (ACS)

    Professor Albert Jeltsch

  81. Recognition and Cleavage of DNA by Type‐II Restriction Endonucleases

    Article • European Journal of Biochemistry, May 1997, Wiley

    Professor Albert Jeltsch

  82. Horizontal gene transfer contributes to the wide distribution and evolution of type II restriction-modification systems

    Article • Journal of Molecular Evolution, February 1996, Springer Science + Business Media

    Professor Albert Jeltsch

  83. Evidence for an evolutionary relationship among type-II restriction endonucleases

    Article • Gene, July 1995, Elsevier

    Professor Albert Jeltsch

  84. Evidence for substrate-assisted catalysis in the DNA cleavage of several restriction endonucleases

    Article • Gene, May 1995, Elsevier

    Professor Albert Jeltsch

  85. Site-directed mutagenesis in the catalytic center of the restriction endonuclease EcoRI

    Article • Gene, May 1995, Elsevier

    Professor Albert Jeltsch

  86. Pausing of the Restriction Endonuclease EcoRI during Linear Diffusion on DNA

    Article • Biochemistry, August 1994, American Chemical Society (ACS)

    Professor Albert Jeltsch

  87. On the catalytic mechanism of EcoRI and EcoRV A detailed proposal based on biochemical results, structural data and molecular modelling

    Article • FEBS Letters, June 1992, Wiley

    Professor Albert Jeltsch

  88. Detection and Quantitation of the Activity of DNA Methyltransferases Using a Biotin/Avidin Microplate Assay

    Article • Springer Science + Business Media

    Professor Albert Jeltsch

  89. High-Throughput Purification of PolyHis-Tagged Recombinant Fusion Proteins

    Article • Springer Science + Business Media

    Professor Albert Jeltsch

  90. Methods for Determining Activity and Specificity of DNA Binding and DNA Cleavage by Class II Restriction Endonucleases

    Article • Springer Science + Business Media

    Professor Albert Jeltsch