All Stories

  1. Master regulator of the onset of triple-negative basal-like breast cancers

    Article • Proceedings of the National Academy of Sciences, July 2022, Proceedings of the National Academy of Sciences

    Akira Suzuki

  2. Alantolactone is a natural product that potently inhibits YAP1/TAZ through promotion of reactive oxygen species accumulation

    Article • Cancer Science, August 2021, Wiley

    Akira Suzuki

  3. TAZ inhibits acinar cell differentiation but promotes immature ductal cell proliferation in adult mouse salivary glands

    Article • Genes to Cells, July 2021, Wiley

    Akira Suzuki

  4. The role of Hippo‐YAP signaling in squamous cell carcinomas

    Article • Cancer Science, December 2020, Wiley

    Akira Suzuki

  5. Endogenous YAP1 activation drives immediate onset of cervical carcinoma in situ in mice

    Article • Cancer Science, August 2020, Wiley

    Akira Suzuki

  6. YAP1 is a potent driver of the onset and progression of oral squamous cell carcinoma

    Article • Science Advances, March 2020, American Association for the Advancement of Science

    Akira Suzuki

  7. MOB1 regulates thymocyte egress and T‐cell survival in mice in a YAP1‐independent manner

    Article • Genes to Cells, July 2019, Wiley

    Akira Suzuki

  8. Hippo pathway controls cell adhesion and context-dependent cell competition to influence skin engraftment efficiency

    Article • The FASEB Journal, April 2019, Federation of American Societies For Experimental Biology (FASEB)

    Akira Suzuki

  9. Loss of Mob1a/b in mice results in chondrodysplasia due to YAP1/TAZ-TEADs-dependent repression of SOX9

    Article • Development, January 2018, The Company of Biologists

    Akira Suzuki

  10. Targeting the Hippo signalling pathway for cancer treatment

    Article • The Journal of Biochemistry, December 2016, Oxford University Press (OUP)

    Akira Suzuki

  11. Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b -deficient mice

    Article • Proceedings of the National Academy of Sciences, December 2015, Proceedings of the National Academy of Sciences

    Akira Suzuki

  12. Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice

    Article • Journal of Clinical Investigation, November 2012, American Society for Clinical Investigation

    Akira Suzuki

  13. A new PICTure of nucleolar stress

    Article • Cancer Science, March 2012, Wiley

    Akira Suzuki

  14. Regulation of the MDM2-P53 pathway and tumor growth by PICT1 via nucleolar RPL11

    Article • Nature Medicine, July 2011, Springer Science + Business Media

    Akira Suzuki

  15. Pten Deficiency in Melanocytes Results in Resistance to Hair Graying and Susceptibility to Carcinogen-Induced Melanomagenesis

    Article • Cancer Research, July 2008, American Association for Cancer Research (AACR)

    Akira Suzuki

  16. Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice

    Article • Journal of Clinical Investigation, October 2007, American Society for Clinical Investigation

    Dr Hiroshi Kubo, Akira Suzuki

  17. The Pten/PI3K pathway governs the homeostasis of Vα14iNKT cells

    Article • Blood, December 2006, American Society of Hematology

    Akira Suzuki

  18. Hyperplasia and Carcinomas in Pten-Deficient Mice and Reduced PTEN Protein in Human Bladder Cancer Patients

    Article • Cancer Research, September 2006, American Association for Cancer Research (AACR)

    Akira Suzuki

  19. The PTEN/PI3K pathway governs normal vascular development and tumor angiogenesis

    Article • Genes & Development, August 2005, Cold Spring Harbor Laboratory Press

    Akira Suzuki

  20. Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas

    Article • Journal of Clinical Investigation, June 2004, American Society for Clinical Investigation

    Akira Suzuki

  21. Critical Roles of Pten in B Cell Homeostasis and Immunoglobulin Class Switch Recombination

    Article • Journal of Experimental Medicine, March 2003, Rockefeller University Press

    Akira Suzuki

  22. T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance

    Article • Immunity, May 2001, Elsevier

    Akira Suzuki

  23. High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

    Article • Current Biology, October 1998, Elsevier

    Akira Suzuki

  24. Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN

    Article • Cell, October 1998, Elsevier

    Akira Suzuki

  25. Brca2 is required for embryonic cellular proliferation in the mouse.

    Article • Genes & Development, May 1997, Cold Spring Harbor Laboratory Press

    Akira Suzuki

  26. CD34-deficient mice have reduced eosinophil accumulation after allergen exposure and show a novel crossreactive 90-kD protein

    Article • Blood, May 1996, American Society of Hematology

    Akira Suzuki