Professor Françoise Van Bambeke

All Stories

1. 
   Activities of Combinations of Antistaphylococcal Antibiotics with Fusidic Acid against Staphylococcal Biofilms inIn VitroStatic and Dynamic Models

   Article • Antimicrobial Agents and Chemotherapy, April 2018, ASM Journals

   Professor Françoise Van Bambeke

2. 
   Cellular Pharmacokinetics and Intracellular Activity of Gepotidacin againstStaphylococcus aureusIsolates with Different Resistance Phenotypes in Models of Cultured Phagocytic Cells

   Article • Antimicrobial Agents and Chemotherapy, January 2018, ASM Journals

   Professor Françoise Van Bambeke

3. 
   Mitochondrial Alterations (Inhibition of Mitochondrial Protein Expression, Oxidative Metabolism, and Ultrastructure) Induced by Linezolid and Tedizolid at Clinically Relevant Concentrations in Cultured Human HL-60 Promyelocytes and THP-1 Monocytes

   Article • Antimicrobial Agents and Chemotherapy, December 2017, ASM Journals

   Professor Françoise Van Bambeke

4. 
   Optimizing β-lactams treatment in critically-ill patients using pharmacokinetics/pharmacodynamics targets: are first conventional doses effective?

   Article • Expert Review of Anti-infective Therapy, June 2017, Taylor & Francis

   Professor Françoise Van Bambeke

5. 
   Acquired resistance to macrolides in Pseudomonas aeruginosa from cystic fibrosis patients

   Article • European Respiratory Journal, May 2017, European Respiratory Society (ERS)

   Professor Françoise Van Bambeke

6. 
   Salicylidene Acylhydrazides and Hydroxyquinolines Act as Inhibitors of Type Three Secretion Systems in Pseudomonas aeruginosa by Distinct Mechanisms

   Article • Antimicrobial Agents and Chemotherapy, April 2017, ASM Journals

   Professor Françoise Van Bambeke

7. 
   Antimicrobial Susceptibility of Pseudomonas aeruginosa Isolated from Cystic Fibrosis Patients in Northern Europe

   Article • Antimicrobial Agents and Chemotherapy, August 2016, ASM Journals

   Professor Françoise Van Bambeke

8. 
   Cellular Pharmacokinetics and Intracellular Activity of the Novel Peptide Deformylase Inhibitor GSK1322322 against Staphylococcus aureus Laboratory and Clinical Strains with Various Resistance Phenotypes: Studies with Human THP-1 Monocytes and J774 Mur...

   Article • Antimicrobial Agents and Chemotherapy, July 2015, ASM Journals

   Professor Françoise Van Bambeke

9. 
   RX-P873, a Novel Protein Synthesis Inhibitor, Accumulates in Human THP-1 Monocytes and Is Active against Intracellular Infections by Gram-Positive (Staphylococcus aureus) and Gram-Negative (Pseudomonas aeruginosa) Bacteria

   Article • Antimicrobial Agents and Chemotherapy, May 2015, ASM Journals

   Professor Françoise Van Bambeke

10. 
    Avibactam confers susceptibility to a large proportion of ceftazidime-resistant Pseudomonas aeruginosa isolates recovered from cystic fibrosis patients

    Article • Journal of Antimicrobial Chemotherapy, January 2015, Oxford University Press (OUP)

    Professor Françoise Van Bambeke

11. 
    Activities of Antibiotic Combinations against Resistant Strains of Pseudomonas aeruginosa in a Model of Infected THP-1 Monocytes

    Article • Antimicrobial Agents and Chemotherapy, October 2014, ASM Journals

    Professor Françoise Van Bambeke

12. 
    Modelled target attainment after meropenem infusion in patients with severe nosocomial pneumonia: the PROMESSE study

    Article • Journal of Antimicrobial Chemotherapy, September 2014, Oxford University Press (OUP)

    Professor Françoise Van Bambeke

13. 
    Characterisation of a collection of Streptococcus pneumoniae isolates from patients suffering from acute exacerbations of chronic bronchitis: In vitro susceptibility to antibiotics and biofilm formation in relation to antibiotic efflux and serotypes/se...

    Article • International Journal of Antimicrobial Agents, September 2014, Elsevier

    Professor Françoise Van Bambeke

14. 
    Comparison of the Antibiotic Activities of Daptomycin, Vancomycin, and the Investigational Fluoroquinolone Delafloxacin against Biofilms from Staphylococcus aureus Clinical Isolates

    Article • Antimicrobial Agents and Chemotherapy, August 2014, ASM Journals

    Professor Françoise Van Bambeke

15. 
    Renaissance of antibiotics against difficult infections: Focus on oritavancin and new ketolides and quinolones

    Article • Annals of Medicine, July 2014, Taylor & Francis

    Professor Françoise Van Bambeke

16. 
    New Amphiphilic Neamine Derivatives Active against Resistant Pseudomonas aeruginosa and Their Interactions with Lipopolysaccharides

    Article • Antimicrobial Agents and Chemotherapy, May 2014, ASM Journals

    Professor Françoise Van Bambeke

17. 
    Development and validation of a high performance liquid chromatography assay for the determination of temocillin in serum of haemodialysis patients

    Article • Journal of Pharmaceutical and Biomedical Analysis, March 2014, Elsevier

    Professor Françoise Van Bambeke

18. 
    Study of Macrophage Functions in Murine J774 Cells and Human Activated THP-1 Cells Exposed to Oritavancin, a Lipoglycopeptide with High Cellular Accumulation

    Article • Antimicrobial Agents and Chemotherapy, January 2014, ASM Journals

    Professor Françoise Van Bambeke

19. 
    Antibiotic Activity against Naive and Induced Streptococcus pneumoniae Biofilms in anIn VitroPharmacodynamic Model

    Article • Antimicrobial Agents and Chemotherapy, December 2013, ASM Journals

    Professor Françoise Van Bambeke

20. 
    Pharmacological Characterization of 7-(4-(Piperazin-1-yl)) Ciprofloxacin Derivatives: Antibacterial Activity, Cellular Accumulation, Susceptibility to Efflux Transporters, and Intracellular Activity

    Article • Pharmaceutical Research, December 2013, Springer Science + Business Media

    Professor Françoise Van Bambeke

21. 
    Macrolides and Ketolides

    Article • November 2013, Springer Science + Business Media

    Professor Françoise Van Bambeke

22. 
    2-Aminobenzothiazole derivatives: Search for new antifungal agents

    Article • European Journal of Medicinal Chemistry, June 2013, Elsevier

    Professor Françoise Van Bambeke

23. 
    P114 Cell safety and subcellular distribution of the oxazolidinone tedizolid inmurine J774 and humanTHP-1 macrophages

    Article • International Journal of Antimicrobial Agents, June 2013, Elsevier

    Professor Françoise Van Bambeke

24. 
    A Combined Pharmacodynamic Quantitative and Qualitative Model Reveals the Potent Activity of Daptomycin and Delafloxacin against Staphylococcus aureus Biofilms

    Article • Antimicrobial Agents and Chemotherapy, April 2013, ASM Journals

    Professor Françoise Van Bambeke

25. 
    Antibiotic activity against small-colony variants of Staphylococcus aureus: review of in vitro, animal and clinical data

    Article • Journal of Antimicrobial Chemotherapy, March 2013, Oxford University Press (OUP)

    Professor Françoise Van Bambeke, Prof. Dr. med. Karsten Becker

26. 
    Pharmacodynamic Evaluation of the Intracellular Activity of Antibiotics towards Pseudomonas aeruginosa PAO1 in a Model of THP-1 Human Monocytes

    Article • Antimicrobial Agents and Chemotherapy, March 2013, ASM Journals

    Professor Françoise Van Bambeke

27. 
    Analysis of the Membrane Proteome of Ciprofloxacin-Resistant Macrophages by Stable Isotope Labeling with Amino Acids in Cell Culture (SILAC)

    Article • PLoS ONE, March 2013, PLOS

    Professor Françoise Van Bambeke

28. 
    Activity of ceftaroline against extracellular (broth) and intracellular (THP-1 monocytes) forms of methicillin-resistant Staphylococcus aureus: comparison with vancomycin, linezolid and daptomycin

    Article • Journal of Antimicrobial Chemotherapy, November 2012, Oxford University Press (OUP)

    Professor Françoise Van Bambeke

29. 
    Intracellular forms of menadione-dependent small-colony variants of methicillin-resistant Staphylococcus aureus are hypersusceptible to  -lactams in a THP-1 cell model due to cooperation between vacuolar acidic pH and oxidant species

    Article • Journal of Antimicrobial Chemotherapy, September 2012, Oxford University Press (OUP)

    Professor Françoise Van Bambeke, Prof. Dr. med. Karsten Becker

30. 
    Influence of the Protein Kinase C Activator Phorbol Myristate Acetate on the Intracellular Activity of Antibiotics against Hemin- and Menadione-Auxotrophic Small-Colony Variant Mutants of Staphylococcus aureus and Their Wild-Type Parental Strain in Hum...

    Article • Antimicrobial Agents and Chemotherapy, September 2012, ASM Journals

    Professor Françoise Van Bambeke, Prof. Dr. med. Karsten Becker

31. 
    Increased Susceptibility of Pseudomonas aeruginosa to Macrolides and Ketolides in Eukaryotic Cell Culture Media and Biological Fluids Due to Decreased Expression of oprM and Increased Outer-Membrane Permeability

    Article • Clinical Infectious Diseases, May 2012, Oxford University Press (OUP)

    Professor Françoise Van Bambeke

32. 
    Pharmacodynamic Evaluation of the Activity of Antibiotics against Hemin- and Menadione-Dependent Small-Colony Variants of Staphylococcus aureus in Models of Extracellular (Broth) and Intracellular (THP-1 Monocytes) Infections

    Article • Antimicrobial Agents and Chemotherapy, May 2012, ASM Journals

    Professor Françoise Van Bambeke, Prof. Dr. med. Karsten Becker

33. 
    Macrophage Killing of Bacterial and Fungal Pathogens Is Not Inhibited by Intense Intracellular Accumulation of the Lipoglycopeptide Antibiotic Oritavancin

    Article • Clinical Infectious Diseases, March 2012, Oxford University Press (OUP)

    Professor Françoise Van Bambeke

34. 
    Antimicrobial susceptibility of Streptococcus pneumoniae isolates from vaccinated and non-vaccinated patients with a clinically confirmed diagnosis of community-acquired pneumonia in Belgium

    Article • International Journal of Antimicrobial Agents, March 2012, Elsevier

    Professor Françoise Van Bambeke

35. 
    Role of MexAB-OprM in intrinsic resistance of Pseudomonas aeruginosa to temocillin and impact on the susceptibility of strains isolated from patients suffering from cystic fibrosis

    Article • Journal of Antimicrobial Chemotherapy, January 2012, Oxford University Press (OUP)

    Professor Françoise Van Bambeke

36. 
    Characterization of Abcc4 Gene Amplification in Stepwise-Selected Mouse J774 Macrophages Resistant to the Topoisomerase II Inhibitor Ciprofloxacin

    Article • PLoS ONE, December 2011, PLOS

    Professor Françoise Van Bambeke

37. 
    Modulation of the expression of ABC transporters in murine (J774) macrophages exposed to large concentrations of the fluoroquinolone antibiotic moxifloxacin

    Article • Toxicology, December 2011, Elsevier

    Professor Françoise Van Bambeke

38. 
    Role of oxidative stress in lysosomal membrane permeabilization and apoptosis induced by gentamicin, an aminoglycoside antibiotic

    Article • Free Radical Biology and Medicine, November 2011, Elsevier

    Professor Françoise Van Bambeke

39. 
    Activity of finafloxacin, a novel fluoroquinolone with increased activity at acid pH, towards extracellular and intracellular Staphylococcus aureus, Listeria monocytogenes and Legionella pneumophila

    Article • International Journal of Antimicrobial Agents, July 2011, Elsevier

    Professor Françoise Van Bambeke

40. 
    Cellular accumulation of fluoroquinolones is not predictive of their intracellular activity: studies with gemifloxacin, moxifloxacin and ciprofloxacin in a pharmacokinetic/pharmacodynamic model of uninfected and infected macrophages

    Article • International Journal of Antimicrobial Agents, July 2011, Elsevier

    Professor Françoise Van Bambeke

41. 
    Activity of Fusidic Acid Against Extracellular and Intracellular Staphylococcus aureus: Influence of pH and Comparison With Linezolid and Clindamycin

    Article • Clinical Infectious Diseases, May 2011, Oxford University Press (OUP)

    Professor Françoise Van Bambeke

42. 
    Editorial [Hot Topic: ABC Transporters: Role in Modulation of Drug Pharmacokinetics and in Physiopathology and Therapeutic Perspectives (Guest Editor: Francoise Van Bambeke)]

    Article • Current Drug Targets, May 2011, Bentham Science Publishers

    Professor Françoise Van Bambeke

43. 
    ABC Multidrug Transporters: Target for Modulation of Drug Pharmacokinetics and Drug-Drug Interactions

    Article • Current Drug Targets, May 2011, Bentham Science Publishers

    Professor Françoise Van Bambeke

44. 
    Fluoroquinolones induce the expression of patA and patB, which encode ABC efflux pumps in Streptococcus pneumoniae

    Article • Journal of Antimicrobial Chemotherapy, March 2011, Oxford University Press (OUP)

    Professor Françoise Van Bambeke

45. 
    Intra- and Extracellular Activities of Dicloxacillin and Linezolid against a ClinicalStaphylococcus aureusStrain with a Small-Colony-Variant Phenotype in anIn VitroModel of THP-1 Macrophages and anIn VivoMouse Peritonitis Model

    Article • Antimicrobial Agents and Chemotherapy, January 2011, ASM Journals

    Professor Françoise Van Bambeke

46. 
    Efflux of novel quinolones in contemporary Streptococcus pneumoniae isolates from community-acquired pneumonia

    Article • Journal of Antimicrobial Chemotherapy, January 2011, Oxford University Press (OUP)

    Professor Françoise Van Bambeke

47. 
    Activity of moxifloxacin against intracellular community-acquired methicillin-resistant Staphylococcus aureus: comparison with clindamycin, linezolid and co-trimoxazole and attempt at defining an intracellular susceptibility breakpoint

    Article • Journal of Antimicrobial Chemotherapy, December 2010, Oxford University Press (OUP)

    Dr Klaudia Kosowska-Shick, Professor Françoise Van Bambeke

48. 
    Contrasting Effects of Acidic pH on the Extracellular and Intracellular Activities of the Anti-Gram-Positive Fluoroquinolones Moxifloxacin and Delafloxacin againstStaphylococcus aureus

    Article • Antimicrobial Agents and Chemotherapy, December 2010, ASM Journals

    Professor Françoise Van Bambeke

49. 
    In vivo development of antimicrobial resistance in Pseudomonas aeruginosa strains isolated from the lower respiratory tract of Intensive Care Unit patients with nosocomial pneumonia and receiving antipseudomonal therapy

    Article • International Journal of Antimicrobial Agents, December 2010, Elsevier

    Professor Françoise Van Bambeke

50. 
    Dynamics and Structural Changes Induced by ATP Binding in SAV1866, a Bacterial ABC Exporter

    Article • The Journal of Physical Chemistry B, November 2010, American Chemical Society (ACS)

    Professor Françoise Van Bambeke

51. 
    Roxithromycin

    Article • October 2010, Taylor & Francis

    Professor Françoise Van Bambeke

52. 
    Erythromycin

    Article • October 2010, Taylor & Francis

    Professor Françoise Van Bambeke

53. 
    Azithromycin

    Article • October 2010, Taylor & Francis

    Professor Françoise Van Bambeke

54. 
    Clarithromycin

    Article • October 2010, Taylor & Francis

    Professor Françoise Van Bambeke

55. 
    Josamycin and Rosaramicin

    Article • October 2010, Taylor & Francis

    Professor Françoise Van Bambeke

56. 
    Interactions of oritavancin, a new semi-synthetic lipoglycopeptide, with lipids extracted from Staphylococcus aureus

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, October 2010, Elsevier

    Professor Françoise Van Bambeke

57. 
    Fluoroquinolones induce the expression of patA and patB, which encode ABC efflux pumps in Streptococcus pneumoniae

    Article • Journal of Antimicrobial Chemotherapy, August 2010, Oxford University Press (OUP)

    Professor Françoise Van Bambeke

58. 
    Intracellular activity of the peptide antibiotic NZ2114: studies with Staphylococcus aureus and human THP-1 monocytes, and comparison with daptomycin and vancomycin

    Article • Journal of Antimicrobial Chemotherapy, June 2010, Oxford University Press (OUP)

    Professor Françoise Van Bambeke

59. 
    Cellular Pharmacodynamics of the Novel Biaryloxazolidinone Radezolid: Studies with Infected Phagocytic and Nonphagocytic cells, Using Staphylococcus aureus, Staphylococcus epidermidis, Listeria monocytogenes, and Legionella pneumophila

    Article • Antimicrobial Agents and Chemotherapy, April 2010, ASM Journals

    Dr Klaudia Kosowska-Shick, Professor Françoise Van Bambeke

60. 
    Cellular Pharmacokinetics of the Novel Biaryloxazolidinone Radezolid in Phagocytic Cells: Studies with Macrophages and Polymorphonuclear Neutrophils

    Article • Antimicrobial Agents and Chemotherapy, April 2010, ASM Journals

    Professor Françoise Van Bambeke

61. 
    Activity of quinupristin/dalfopristin against extracellular and intracellular Staphylococcus aureus with various resistance phenotypes

    Article • Journal of Antimicrobial Chemotherapy, April 2010, Oxford University Press (OUP)

    Professor Françoise Van Bambeke

62. 
    Intra- and Extracellular Activities of Dicloxacillin against Staphylococcus aureus In Vivo and In Vitro

    Article • Antimicrobial Agents and Chemotherapy, March 2010, ASM Journals

    Professor Françoise Van Bambeke

63. 
    Intra- and extracellular activity of linezolid against Staphylococcus aureus in vivo and in vitro

    Article • Journal of Antimicrobial Chemotherapy, March 2010, Oxford University Press (OUP)

    Professor Françoise Van Bambeke

64. 
    ChemInform Abstract: Synthesis and Biological Evaluation of 2‐Mercapto‐1,3‐benzothiazole Derivatives with Potential Antimicrobial Activity.

    Article • ChemInform, January 2010, Wiley

    Professor Françoise Van Bambeke

65. 
    Penicillin-binding Proteins (PBP) and Lmo0441 (a PBP-like protein) play a role in Beta-lactam sensitivity of Listeria monocytogenes

    Article • Gut Pathogens, December 2009, Springer Science + Business Media

    Professor Françoise Van Bambeke

66. 
    Isolation and 2‐D‐DIGE proteomic analysis of intracellular and extracellular forms of Listeria monocytogenes

    Article • PROTEOMICS, December 2009, Wiley

    Professor Françoise Van Bambeke

67. 
    Role of rsbU and Staphyloxanthin in Phagocytosis and Intracellular Growth of Staphylococcus aureus in Human Macrophages and Endothelial Cells

    Article • The Journal of Infectious Diseases, November 2009, Oxford University Press (OUP)

    Professor Françoise Van Bambeke

68. 
    Synthesis and Biological Evaluation of 2‐Mercapto‐1,3‐benzothiazole Derivatives with Potential Antimicrobial Activity

    Article • Archiv der Pharmazie, September 2009, Wiley

    Professor Françoise Van Bambeke

69. 
    Cellular pharmacokinetics and intracellular activity of torezolid (TR-700): studies with human macrophage (THP-1) and endothelial (HUVEC) cell lines

    Article • Journal of Antimicrobial Chemotherapy, September 2009, Oxford University Press (OUP)

    Professor Françoise Van Bambeke

70. 
    Plectasin Shows Intracellular Activity against Staphylococcus aureus in Human THP-1 Monocytes and in a Mouse Peritonitis Model

    Article • Antimicrobial Agents and Chemotherapy, September 2009, ASM Journals

    Professor Françoise Van Bambeke

71. 
    Interactions of oritavancin, a new lipoglycopeptide derived from vancomycin, with phospholipid bilayers: Effect on membrane permeability and nanoscale lipid membrane organization

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, September 2009, Elsevier

    Professor Françoise Van Bambeke

72. 
    O31 Radezolid (RX-1741), a novel oxazolidinone, accumulates extensively within human macrophages and PMNs and shows activity towards intracellular linezolid-sensitive and linezolid-resistant Staphylococcus aureus

    Article • International Journal of Antimicrobial Agents, July 2009, Elsevier

    Dr Klaudia Kosowska-Shick, Professor Françoise Van Bambeke

73. 
    Pharmacodynamie des antibiotiques dans le LCR : principes et conséquences (facteurs prédictifs d’efficacité)

    Article • Médecine et Maladies Infectieuses, July 2009, Elsevier

    Professor Françoise Van Bambeke

74. 
    DD-Ligases as a Potential Target for Antibiotics: Past, Present and Future

    Article • Current Medicinal Chemistry, July 2009, Bentham Science Publishers

    Professor Françoise Van Bambeke

75. 
    P313 Analysis of guidelines for treatment of community-acquired pneumonia (CAP) in outpatients

    Article • International Journal of Antimicrobial Agents, July 2009, Elsevier

    Professor Françoise Van Bambeke

76. 
    P3 Pharmacodynamic evaluation of the intracellular activity of CEM-101, a novel ketolide, towards Staphylococcus aureus, Listeria monocytogenes, and Legionella pneumophila in human THP-1 macrophages

    Article • International Journal of Antimicrobial Agents, July 2009, Elsevier

    Professor Françoise Van Bambeke

77. 
    P71 Antibiotic resistance of clinical isolates of Pseudomonas aeruginosa (PA) collected from intensive care units (ICU) patients with nosocomial pneumonia in 5 Belgian hospitals during the 2004–2008 period using EUCAST breakpoints

    Article • International Journal of Antimicrobial Agents, July 2009, Elsevier

    Professor Françoise Van Bambeke

78. 
    Cellular Accumulation and Pharmacodynamic Evaluation of the Intracellular Activity of CEM-101, a Novel Fluoroketolide, against Staphylococcus aureus, Listeria monocytogenes, and Legionella pneumophila in Human THP-1 Macrophages

    Article • Antimicrobial Agents and Chemotherapy, June 2009, ASM Journals

    Professor Françoise Van Bambeke

79. 
    Identification of the Efflux Transporter of the Fluoroquinolone Antibiotic Ciprofloxacin in Murine Macrophages: Studies with Ciprofloxacin-Resistant Cells

    Article • Antimicrobial Agents and Chemotherapy, March 2009, ASM Journals

    Professor Françoise Van Bambeke

80. 
    Activities of Ceftobiprole and Other Cephalosporins against Extracellular and Intracellular (THP-1 Macrophages and Keratinocytes) Forms of Methicillin-Susceptible and Methicillin-Resistant Staphylococcus aureus

    Article • Antimicrobial Agents and Chemotherapy, March 2009, ASM Journals

    Professor Françoise Van Bambeke

81. 
    Intracellular Activity of Antibiotics in a Model of Human THP-1 Macrophages Infected by a Staphylococcus aureus Small-Colony Variant Strain Isolated from a Cystic Fibrosis Patient: Study of Antibiotic Combinations

    Article • Antimicrobial Agents and Chemotherapy, February 2009, ASM Journals

    Professor Françoise Van Bambeke

82. 
    Intracellular Activity of Antibiotics in a Model of Human THP-1 Macrophages Infected by a Staphylococcus aureus Small-Colony Variant Strain Isolated from a Cystic Fibrosis Patient: Pharmacodynamic Evaluation and Comparison with Isogenic Normal-Phenotyp...

    Article • Antimicrobial Agents and Chemotherapy, February 2009, ASM Journals

    Professor Françoise Van Bambeke

83. 
    Molecular models of human P-glycoprotein in two different catalytic states

    Article • BMC Structural Biology, January 2009, Springer Science + Business Media

    Professor Françoise Van Bambeke

84. 
    Safety Profile of the Respiratory Fluoroquinolone Moxifloxacin

    Article • Drug Safety, January 2009, Springer Science + Business Media

    Professor Françoise Van Bambeke

85. 
    Interactions of ciprofloxacin with DPPC and DPPG: Fluorescence anisotropy, ATR-FTIR and 31P NMR spectroscopies and conformational analysis

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, November 2008, Elsevier

    Professor Françoise Van Bambeke

86. 
    Activities of antistaphylococcal antibiotics towards the extracellular and intraphagocytic forms of Staphylococcus aureus isolates from a patient with persistent bacteraemia and endocarditis

    Article • Clinical Microbiology and Infection, August 2008, Elsevier

    Dr Klaudia Kosowska-Shick, Professor Françoise Van Bambeke

87. 
    Cooperation between Prokaryotic (Lde) and Eukaryotic (MRP) Efflux Transporters in J774 Macrophages Infected with Listeria monocytogenes: Studies with Ciprofloxacin and Moxifloxacin

    Article • Antimicrobial Agents and Chemotherapy, June 2008, ASM Journals

    Professor Françoise Van Bambeke

88. 
    Contrasting effects of human THP-1 cell differentiation on levofloxacin and moxifloxacin intracellular accumulation and activity against Staphylococcus aureus and Listeria monocytogenes

    Article • Journal of Antimicrobial Chemotherapy, June 2008, Oxford University Press (OUP)

    Professor Françoise Van Bambeke

89. 
    Restoration of Susceptibility of Intracellular Methicillin-Resistant Staphylococcus aureus to β-Lactams: Comparison of Strains, Cells, and Antibiotics

    Article • Antimicrobial Agents and Chemotherapy, June 2008, ASM Journals

    Professor Françoise Van Bambeke

90. 
    Apoptosis Induced by Aminoglycosides in LLC-PK1 Cells: Comparative Study of Neomycin, Gentamicin, Amikacin, and Isepamicin Using Electroporation

    Article • Antimicrobial Agents and Chemotherapy, April 2008, ASM Journals

    Professor Françoise Van Bambeke

91. 
    Cellular pharmacokinetics of telavancin, a novel lipoglycopeptide antibiotic, and analysis of lysosomal changes in cultured eukaryotic cells (J774 mouse macrophages and rat embryonic fibroblasts)

    Article • Journal of Antimicrobial Chemotherapy, March 2008, Oxford University Press (OUP)

    Professor Françoise Van Bambeke

92. 
    Restoration of Susceptibility of Methicillin-resistant Staphylococcus aureus to  -Lactam Antibiotics by Acidic pH: ROLE OF PENICILLIN-BINDING PROTEIN PBP 2a

    Article • Journal of Biological Chemistry, March 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Françoise Van Bambeke

93. 
    The bacterial envelope as a target for novel anti-MRSA antibiotics

    Article • Trends in Pharmacological Sciences, March 2008, Elsevier

    Professor Françoise Van Bambeke

94. 
    Ketolides: pharmacological profile and rational positioning in the treatment of respiratory tract infections

    Article • Expert Opinion on Pharmacotherapy, January 2008, Informa Healthcare

    Professor Françoise Van Bambeke

95. 
    Selection of quinolone resistance in Streptococcus pneumoniae exposed in vitro to subinhibitory drug concentrations

    Article • Journal of Antimicrobial Chemotherapy, September 2007, Oxford University Press (OUP)

    Professor Françoise Van Bambeke

96. 
    Pseudomonas aeruginosa : résistance et options thérapeutiques à l’aube du deuxième millénaire

    Article • Antibiotiques, September 2007, Elsevier

    Professor Françoise Van Bambeke

97. 
    Passive diffusion of polymeric surfactants across lipid bilayers

    Article • Journal of Controlled Release, July 2007, Elsevier

    Professor Françoise Van Bambeke

98. 
    Modulation of the Cellular Accumulation and Intracellular Activity of Daptomycin towards Phagocytized Staphylococcus aureus by the P-Glycoprotein (MDR1) Efflux Transporter in Human THP-1 Macrophages and Madin-Darby Canine Kidney Cells

    Article • Antimicrobial Agents and Chemotherapy, June 2007, ASM Journals

    Professor Françoise Van Bambeke

99. 
    Pseudomonas aeruginosa: resistance and therapeutic options at the turn of the new millennium

    Article • Clinical Microbiology and Infection, June 2007, Elsevier

    Professor Françoise Van Bambeke

100. 
     P829 Intracellular activity of daptomycin against methicillin-sensitive, methicillin-resistant and vancomycin-intermediate S. aureus

     Article • International Journal of Antimicrobial Agents, March 2007, Elsevier

     Professor Françoise Van Bambeke

101. 
     P1358 Prevalence of Mex-mediated resistance in Pseudomonas aeruginosa isolates from patients with ventilator-associated pneumonia in 4 Belgian hospitals

     Article • International Journal of Antimicrobial Agents, March 2007, Elsevier

     Professor Françoise Van Bambeke

102. 
     P2067 Ciprofloxacin and doxorubicin are substrates of different multidrug resistance-related proteins efflux transporters in J774 macrophages

     Article • International Journal of Antimicrobial Agents, March 2007, Elsevier

     Professor Françoise Van Bambeke

103. 
     O428 Aminoglycoside-induced apoptosis in cultured renal (LLC-PK1) and non-renal (J774 macrophages) cells: comparison between gentamicin and amikacin

     Article • International Journal of Antimicrobial Agents, March 2007, Elsevier

     Professor Françoise Van Bambeke

104. 
     O429 Inhibitors and activator of the P-glycoprotein (P gp) efflux pump modulate the accumulation of daptomycin (DAP) in THP-1 macrophages and its intracellular activity towards Staphylococcus aureus

     Article • International Journal of Antimicrobial Agents, March 2007, Elsevier

     Professor Françoise Van Bambeke

105. 
     P703 Comparative activity of moxifioxacin vs. trimethoprim-sulfamethoxazole, cloxacillin, linezolid, clindamycin, and ciprofioxacin against intracellular methicillin-sensitive and community-acquired methicillin-resistant S. aureus

     Article • International Journal of Antimicrobial Agents, March 2007, Elsevier

     Professor Françoise Van Bambeke

106. 
     P2058 Extracellular and intracellular activities of quinupristin-dalfopristin (Synercid) against Staphylococcus aureus, with different resistant phenotypes (MSSA, MRSA, VISA)

     Article • International Journal of Antimicrobial Agents, March 2007, Elsevier

     Professor Françoise Van Bambeke

107. 
     Role of Acidic pH in the Susceptibility of Intraphagocytic Methicillin-Resistant Staphylococcus aureus Strains to Meropenem and Cloxacillin

     Article • Antimicrobial Agents and Chemotherapy, February 2007, ASM Journals

     Professor Françoise Van Bambeke

108. 
     A combined phenotypic and genotypic method for the detection of Mex efflux pumps in Pseudomonas aeruginosa

     Article • Journal of Antimicrobial Chemotherapy, January 2007, Oxford University Press (OUP)

     Professor Françoise Van Bambeke

109. 
     Multidrug-Resistant Streptococcus pneumoniae Infections

     Article • Drugs, January 2007, Springer Science + Business Media

     Professor Françoise Van Bambeke

110. 
     Combined effect of pH and concentration on the activities of gentamicin and oxacillin against Staphylococcus aureus in pharmacodynamic models of extracellular and intracellular infections

     Article • Journal of Antimicrobial Chemotherapy, November 2006, Oxford University Press (OUP)

     Professor Françoise Van Bambeke

111. 
     Evaluation of the extracellular and intracellular activities (human THP-1 macrophages) of telavancin versus vancomycin against methicillin-susceptible, methicillin-resistant, vancomycin-intermediate and vancomycin-resistant Staphylococcus aureus

     Article • Journal of Antimicrobial Chemotherapy, October 2006, Oxford University Press (OUP)

     Professor Françoise Van Bambeke

112. 
     Cellular Accumulation and Activity of Quinolones in Ciprofloxacin-Resistant J774 Macrophages

     Article • Antimicrobial Agents and Chemotherapy, May 2006, ASM Journals

     Professor Françoise Van Bambeke

113. 
     Gentamicin Causes Apoptosis at Low Concentrations in Renal LLC-PK1 Cells Subjected to Electroporation

     Article • Antimicrobial Agents and Chemotherapy, April 2006, ASM Journals

     Professor Françoise Van Bambeke

114. 
     Pharmacodynamic Evaluation of the Intracellular Activities of Antibiotics against Staphylococcus aureus in a Model of THP-1 Macrophages

     Article • Antimicrobial Agents and Chemotherapy, March 2006, ASM Journals

     Professor Françoise Van Bambeke

115. 
     Predicting the three‐dimensional structure of human P‐glycoprotein in absence of ATP by computational techniques embodying crosslinking data: Insight into the mechanism of ligand migration and binding sites

     Article • Proteins Structure Function and Bioinformatics, February 2006, Wiley

     Professor Françoise Van Bambeke

116. 
     Gentamicin-induced apoptosis in LLC-PK1 cells: Involvement of lysosomes and mitochondria

     Article • Toxicology and Applied Pharmacology, August 2005, Elsevier

     Professor Françoise Van Bambeke

117. 
     Influence of Efflux Transporters on the Accumulation and Efflux of Four Quinolones (Ciprofloxacin, Levofloxacin, Garenoxacin, and Moxifloxacin) in J774 Macrophages

     Article • Antimicrobial Agents and Chemotherapy, June 2005, ASM Journals

     Professor Françoise Van Bambeke

118. 
     Mixed-Lipid Storage Disorder Induced in Macrophages and Fibroblasts by Oritavancin (LY333328), a New Glycopeptide Antibiotic with Exceptional Cellular Accumulation

     Article • Antimicrobial Agents and Chemotherapy, May 2005, ASM Journals

     Professor Françoise Van Bambeke

119. 
     Accumulation and Oriented Transport of Ampicillin in Caco-2 Cells from Its Pivaloyloxymethylester Prodrug, Pivampicillin

     Article • Antimicrobial Agents and Chemotherapy, April 2005, ASM Journals

     Professor Françoise Van Bambeke

120. 
     Quinolones in 2005: an update

     Article • Clinical Microbiology and Infection, April 2005, Elsevier

     Professor Françoise Van Bambeke

121. 
     Actieve antibiotica-efflux en bacteriële resistentie: actualisatie en implicaties

     Article • Tijdschrift voor Geneeskunde, January 2005, Peeters Publishers

     Professor Françoise Van Bambeke

122. 
     Actieve antibiotica-efflux en bacteriële resistentie: actualisatie en implicaties

     Article • Tijdschrift voor Geneeskunde, January 2005, Peeters Publishers

     Professor Françoise Van Bambeke

123. 
     Actieve antibiotica-efflux en bacteriële resistentie: actualisatie en implicaties

     Article • Tijdschrift voor Geneeskunde, January 2005, Peeters Publishers

     Professor Françoise Van Bambeke

124. 
     Modulation of the in vitro activity of lysosomal phospholipase A1 by membrane lipids

     Article • Chemistry and Physics of Lipids, January 2005, Elsevier

     Professor Françoise Van Bambeke

125. 
     Glycopeptides in clinical development: pharmacological profile and clinical perspectives

     Article • Current Opinion in Pharmacology, October 2004, Elsevier

     Professor Françoise Van Bambeke

126. 
     Cellular Pharmacokinetics and Pharmacodynamics of the Glycopeptide Antibiotic Oritavancin (LY333328) in a Model of J774 Mouse Macrophages

     Article • Antimicrobial Agents and Chemotherapy, August 2004, ASM Journals

     Professor Françoise Van Bambeke

127. 
     Active Efflux of Ciprofloxacin from J774 Macrophages through an MRP-Like Transporter

     Article • Antimicrobial Agents and Chemotherapy, July 2004, ASM Journals

     Professor Françoise Van Bambeke

128. 
     Impairment of Growth of Listeria monocytogenes in THP‐1 Macrophages by Granulocyte Macrophage Colony‐Stimulating Factor: Release of Tumor Necrosis Factor–α and Nitric Oxide

     Article • The Journal of Infectious Diseases, June 2004, Oxford University Press (OUP)

     Professor Françoise Van Bambeke

129. 
     Glycopeptide Antibiotics

     Article • Drugs, January 2004, Springer Science + Business Media

     Professor Françoise Van Bambeke

130. 
     Cocaine induces a mixed lysosomal lipidosis in cultured fibroblasts, by inactivation of acid sphingomyelinase and inhibition of phospholipase A1

     Article • Toxicology and Applied Pharmacology, January 2004, Elsevier

     Professor Françoise Van Bambeke

131. 
     Intracellular pharmacodynamics of antibiotics

     Article • Infectious Disease Clinics of North America, September 2003, Elsevier

     Professor Françoise Van Bambeke

132. 
     Quantitative Analysis of Gentamicin, Azithromycin, Telithromycin, Ciprofloxacin, Moxifloxacin, and Oritavancin (LY333328) Activities against Intracellular Staphylococcus aureus in Mouse J774 Macrophages

     Article • Antimicrobial Agents and Chemotherapy, July 2003, ASM Journals

     Professor Françoise Van Bambeke

133. 
     Antibiotic efflux pumps in eukaryotic cells: occurrence and impact on antibiotic cellular pharmacokinetics, pharmacodynamics and toxicodynamics

     Article • Journal of Antimicrobial Chemotherapy, April 2003, Oxford University Press (OUP)

     Professor Françoise Van Bambeke

134. 
     Antibiotic efflux pumps in prokaryotic cells: occurrence, impact on resistance and strategies for the future of antimicrobial therapy

     Article • Journal of Antimicrobial Chemotherapy, April 2003, Oxford University Press (OUP)

     Professor Françoise Van Bambeke

135. 
     Influence of P-Glycoprotein Inhibitors on Accumulation of Macrolides in J774 Murine Macrophages

     Article • Antimicrobial Agents and Chemotherapy, March 2003, ASM Journals

     Professor Françoise Van Bambeke

136. 
     Piracetam inhibits the lipid-destabilising effect of the amyloid peptide Aβ C-terminal fragment

     Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, January 2003, Elsevier

     Professor Françoise Van Bambeke

137. 
     Membrane destabilization induced by β-amyloid peptide 29-42: Importance of the amino-terminus

     Article • Chemistry and Physics of Lipids, December 2002, Elsevier

     Professor Françoise Van Bambeke

138. 
     Comparative Intracellular (THP-1 Macrophage) and Extracellular Activities of β-Lactams, Azithromycin, Gentamicin, and Fluoroquinolones against Listeria monocytogenes at Clinically Relevant Concentrations

     Article • Antimicrobial Agents and Chemotherapy, July 2002, ASM Journals

     Professor Françoise Van Bambeke

139. 
     Experimental and Conformational Analyses of Interactions between Butenafine and Lipids

     Article • Antimicrobial Agents and Chemotherapy, December 2001, ASM Journals

     Professor Françoise Van Bambeke

140. 
     Macrolides: pharmacokinetics and pharmacodynamics

     Article • International Journal of Antimicrobial Agents, September 2001, Elsevier

     Professor Françoise Van Bambeke

141. 
     Erytromycine en de huidige neomacroliden: klinisch gebruik en perspectieven

     Article • Tijdschrift voor Geneeskunde, January 2001, Peeters Publishers

     Professor Françoise Van Bambeke

142. 
     Erytromycine en de huidige neomacroliden: klinisch gebruik en perspectieven

     Article • Tijdschrift voor Geneeskunde, January 2001, Peeters Publishers

     Professor Françoise Van Bambeke

143. 
     Antibiotic efflux pumps

     Article • Biochemical Pharmacology, August 2000, Elsevier

     Professor Françoise Van Bambeke

144. 
     Biophysical studies and intracellular destabilization of pH‐sensitive liposomes

     Article • Lipids, February 2000, Wiley

     Professor Françoise Van Bambeke

145. 
     Lysosomal alterations induced in cultured rat fibroblasts by long-term exposure to low concentrations of azithromycin

     Article • Journal of Antimicrobial Chemotherapy, December 1998, Oxford University Press (OUP)

     Professor Françoise Van Bambeke

146. 
     Hyperactivity of cathepsin B and other lysosomal enzymes in fibroblasts exposed to azithromycin, a dicationic macrolide antibiotic with exceptional tissue accumulation

     Article • FEBS Letters, October 1996, Wiley

     Professor Françoise Van Bambeke

147. 
     Interaction of the macrolide azithromycin with phospholipids. I. Inhibition of lysosomal phospholipase A1 activity

     Article • European Journal of Pharmacology, October 1996, Elsevier

     Professor Françoise Van Bambeke

148. 
     Interaction of the macrolide azithromycin with phospholipids. II. Biophysical and computer-aided conformational studies

     Article • European Journal of Pharmacology, October 1996, Elsevier

     Professor Françoise Van Bambeke

149. 
     Aminoglycoside antibiotics prevent the formation of non-bilayer structures in negatively-charged membranes. Comparative studies using fusogenic (bis(β-diethylaminoethylether)hexestrol) and aggregating (spermine) agents

     Article • Chemistry and Physics of Lipids, March 1996, Elsevier

     Professor Françoise Van Bambeke

150. 
     Aminoglycoside antibiotics induce aggregation but not fusion of negatively-charged liposomes

     Article • European Journal of Pharmacology Molecular Pharmacology, April 1995, Elsevier

     Professor Françoise Van Bambeke

151. 
     Alterations in membrane permeability induced by aminoglycoside antibiotics: studies on liposomes and cultured cells

     Article • European Journal of Pharmacology Molecular Pharmacology, October 1993, Elsevier

     Professor Françoise Van Bambeke