All Stories

  1. Skin Sensitization Potential of Sensitizers in the Presence of Metal Oxide Nanoparticles In Vitro

    Article • Nanomaterials, November 2024, MDPI AG

    Eleonore Fröhlich

  2. Personalization of lipid-based oral dosage forms via filament-based 3D-printing

    Article • Applied Materials Today, October 2024, Elsevier

    Eleonore Fröhlich

  3. Archaeosomes for Oral Drug Delivery: From Continuous Microfluidics Production to Powdered Formulations

    Article • Pharmaceutics, May 2024, MDPI AG

    Eleonore Fröhlich

  4. Animals in Respiratory Research

    Article • International Journal of Molecular Sciences, March 2024, MDPI AG

    Eleonore Fröhlich

  5. Pars Distalis and Pars Tuberalis Thyroid-Stimulating Hormones and Their Roles in Macro-Thyroid-Stimulating Hormone Formation

    Article • International Journal of Molecular Sciences, July 2023, MDPI AG

    Eleonore Fröhlich

  6. Lipid Nanoparticles as a Shuttle for Anti-Adipogenic miRNAs to Human Adipocytes

    Article • Pharmaceutics, July 2023, MDPI AG

    Eleonore Fröhlich

  7. Lipid-based particle engineering via spray-drying for targeted delivery of antibiotics to the lung

    Article • International Journal of Pharmaceutics, July 2023, Elsevier

    Eleonore Fröhlich

  8. The Variety of 3D Breast Cancer Models for the Study of Tumor Physiology and Drug Screening

    Article • International Journal of Molecular Sciences, April 2023, MDPI AG

    Eleonore Fröhlich

  9. Assessment of Carbon Nanotubes on Barrier Function, Ciliary Beating Frequency and Cytokine Release in In Vitro Models of the Respiratory Tract

    Article • Nanomaterials, February 2023, MDPI AG

    Eleonore Fröhlich

  10. Insight into Potential Interactions of Thyroid Hormones, Sex Hormones and Their Stimulating Hormones in the Development of Non-Alcoholic Fatty Liver Disease

    Article • Metabolites, August 2022, MDPI AG

    Eleonore Fröhlich

  11. Non-Cellular Layers of the Respiratory Tract: Protection against Pathogens and Target for Drug Delivery

    Article • Pharmaceutics, May 2022, MDPI AG

    Eleonore Fröhlich

  12. Replacement Strategies for Animal Studies in Inhalation Testing

    Article • Sci, December 2021, MDPI AG

    Eleonore Fröhlich

  13. Acute Respiratory Distress Syndrome: Focus on Viral Origin and Role of Pulmonary Lymphatics

    Article • Biomedicines, November 2021, MDPI AG

    Eleonore Fröhlich

  14. Initial Biological Assessment of Upconversion Nanohybrids

    Article • Biomedicines, October 2021, MDPI AG

    Eleonore Fröhlich

  15. “Biology and Medicine”: A Section of Nanomaterials Addressing Interactions of Nanomaterials with All Forms of Life

    Article • Nanomaterials, September 2021, MDPI AG

    Eleonore Fröhlich

  16. Nanoparticles: Promising Auxiliary Agents for Diagnosis and Therapy of Thyroid Cancers

    Article • Cancers, August 2021, MDPI AG

    Eleonore Fröhlich

  17. Replacement Strategies for Animal Studies in Inhalation Testing

    Article • May 2021, MDPI AG

    Eleonore Fröhlich

  18. Cytokine-Mediated Inflammation in the Oral Cavity and Its Effect on Lipid Nanocarriers

    Article • Nanomaterials, May 2021, MDPI AG

    Eleonore Fröhlich

  19. Screening for Effects of Inhaled Nanoparticles in Cell Culture Models for Prolonged Exposure

    Article • Nanomaterials, February 2021, MDPI AG

    Eleonore Fröhlich

  20. On Absorption Modeling and Food Effect Prediction of Rivaroxaban, a BCS II Drug Orally Administered as an Immediate-Release Tablet

    Article • Pharmaceutics, February 2021, MDPI AG

    Eleonore Fröhlich

  21. Therapeutic Potential of Mesenchymal Stem Cells and Their Products in Lung Diseases—Intravenous Administration versus Inhalation

    Article • Pharmaceutics, February 2021, MDPI AG

    Eleonore Fröhlich

  22. Different Sensitivity of Macrophages to Phospholipidosis Induction by Amphiphilic Cationic Drugs

    Article • International Journal of Molecular Sciences, November 2020, MDPI AG

    Eleonore Fröhlich

  23. Issues with Cancer Spheroid Models in Therapeutic Drug Screening

    Article • Current Pharmaceutical Design, June 2020, Bentham Science Publishers

    Eleonore Fröhlich

  24. Understanding and Preventing Adverse Effects of Tacrolimus Metabolization in Transplant Patients

    Article • Current Drug Metabolism, January 2020, Bentham Science Publishers

    Eleonore Fröhlich

  25. Impact of drug particle shape on permeability and cellular uptake in the lung

    Article • European Journal of Pharmaceutical Sciences, November 2019, Elsevier

    Eleonore Fröhlich

  26. Functional dextran amino acid ester particles derived from N-protected S-trityl-L-cysteine

    Article • Colloids and Surfaces B Biointerfaces, September 2019, Elsevier

    Eleonore Fröhlich

  27. Cytotoxicity screening of emulsifiers for pulmonary application of lipid nanoparticles

    Article • European Journal of Pharmaceutical Sciences, August 2019, Elsevier

    Eleonore Fröhlich

  28. Biological Obstacles for Identifying In Vitro-In Vivo Correlations of Orally Inhaled Formulations

    Article • Pharmaceutics, July 2019, MDPI AG

    Eleonore Fröhlich

  29. Delivery of Dry Powders to the Lungs: Influence of Particle Attributes from a Biological and Technological Point of View

    Article • Current Drug Delivery, February 2019, Bentham Science Publishers

    Eleonore Fröhlich

  30. An automatable platform for genotoxicity testing of nanomaterials based on the fluorometric γ-H2AX assay reveals no genotoxicity of properly surface-shielded cadmium-based quantum dots

    Article • Nanoscale, January 2019, Royal Society of Chemistry

    Eleonore Fröhlich

  31. Comparison of conventional and advanced in vitro models in the toxicity testing of nanoparticles

    Article • Artificial Cells Nanomedicine and Biotechnology, June 2018, Taylor & Francis

    Eleonore Fröhlich

  32. The Development of Indicator Cotton Swabs for the Detection of pH in Wounds

    Article • Sensors, June 2017, MDPI AG

    Eleonore Fröhlich

  33. Amphiphilic coatings for the protection of upconverting nanoparticles against dissolution in aqueous media

    Article • Dalton Transactions, January 2017, Royal Society of Chemistry

    Eleonore Fröhlich

  34. An in vitro and in silico study of the impact of engineered surface modifications on drug detachment from model carriers

    Article • International Journal of Pharmaceutics, November 2016, Elsevier

    Eleonore Fröhlich

  35. Cellular elimination of nanoparticles

    Article • Environmental Toxicology and Pharmacology, September 2016, Elsevier

    Eleonore Fröhlich

  36. Oral uptake of nanoparticles: human relevance and the role of in vitro systems

    Article • Archives of Toxicology, June 2016, Springer Science + Business Media

    Eleonore Fröhlich

  37. Cytotoxicity of Nanoparticles Contained in Food on Intestinal Cells and the Gut Microbiota

    Article • International Journal of Molecular Sciences, April 2016, MDPI AG

    Eleonore Fröhlich

  38. MECHANISMS IN ENDOCRINOLOGY: Impact of isolated TSH levels in and out of normal range on different tissues

    Article • European Journal of Endocrinology, February 2016, Bioscientifica

    Eleonore Fröhlich

  39. Permeation of Therapeutic Drugs in Different Formulations across the Airway Epithelium In Vitro

    Article • PLoS ONE, August 2015, PLOS

    Eleonore Fröhlich

  40. In Vitro Assessment of Chronic Nanoparticle Effects on Respiratory Cells

    Article • July 2015, IntechOpen

    Eleonore Fröhlich

  41. Atomic force microscopy as analytical tool to study physico-mechanical properties of intestinal cells

    Article • Beilstein Journal of Nanotechnology, July 2015, Beilstein Institut

    Eleonore Fröhlich

  42. Intracellular calcium levels as screening tool for nanoparticle toxicity

    Article • Journal of Applied Toxicology, May 2015, Wiley

    Eleonore Fröhlich

  43. Value of phagocyte function screening for immunotoxicity of nanoparticles in vivo

    Article • International Journal of Nanomedicine, May 2015, Dove Medical Press

    Eleonore Fröhlich

  44. Interactions between nano-TiO2 and the oral cavity: Impact of nanomaterial surface hydrophilicity/hydrophobicity

    Article • Journal of Hazardous Materials, April 2015, Elsevier

    Eleonore Fröhlich

  45. Chemotherapy and Chemoprevention by Thiazolidinediones

    Article • BioMed Research International, January 2015, Hindawi Publishing Corporation

    Eleonore Fröhlich

  46. Analogies in the Adverse Immune Effects of Wear Particles, Environmental Particles, and Medicinal Nanoparticles

    Article • October 2014, Taylor & Francis

    Eleonore Fröhlich

  47. Use of whole genome expression analysis in the toxicity screening of nanoparticles

    Article • Toxicology and Applied Pharmacology, October 2014, Elsevier

    Eleonore Fröhlich

  48. The current role of targeted therapies to induce radioiodine uptake in thyroid cancer

    Article • Cancer Treatment Reviews, June 2014, Elsevier

    Eleonore Fröhlich

  49. The buccal mucosa as a route for TiO2nanoparticle uptake

    Article • Nanotoxicology, May 2014, Taylor & Francis

    Eleonore Fröhlich

  50. Photohardening of polymorphic light eruption patients decreases baseline epidermalLangerhans cell density while increasing mast cell numbers in the papillary dermis

    Article • Experimental Dermatology, May 2014, Wiley

    Eleonore Fröhlich

  51. Toxicological Assessment of Inhaled Nanoparticles: Role of in Vivo, ex Vivo, in Vitro, and in Silico Studies

    Article • International Journal of Molecular Sciences, March 2014, MDPI AG

    Eleonore Fröhlich

  52. Development of an Advanced Intestinal in Vitro Triple Culture Permeability Model To Study Transport of Nanoparticles

    Article • Molecular Pharmaceutics, February 2014, American Chemical Society (ACS)

    Eleonore Fröhlich

  53. Reaction of monocytes to polystyrene and silica nanoparticles in short-term and long-term exposures

    Article • Toxicology Research, January 2014, Oxford University Press (OUP)

    Eleonore Fröhlich

  54. Mucus as Barrier for Drug Delivery by Nanoparticles

    Article • Journal of Nanoscience and Nanotechnology, January 2014, American Scientific Publishers

    Eleonore Fröhlich

  55. Mucus as Physiological Barrier to Intracellular Delivery

    Article • January 2014, Springer Science + Business Media

    Eleonore Fröhlich

  56. Gas Permeation, Mechanical Behavior and Cytocompatibility of Ultrathin Pure and Doped Diamond-Like Carbon and Silicon Oxide Films

    Article • Coatings, December 2013, MDPI AG

    Eleonore Fröhlich

  57. Liposomes coated with thiolated chitosan enhance oral peptide delivery to rats

    Article • Journal of Controlled Release, December 2013, Elsevier

    Eleonore Fröhlich

  58. Nano-sized and micro-sized polystyrene particles affect phagocyte function

    Article • Cell Biology and Toxicology, November 2013, Springer Science + Business Media

    Eleonore Fröhlich

  59. Cellular Targets and Mechanisms in the Cytotoxic Action of Non-biodegradable Engineered Nanoparticles

    Article • Current Drug Metabolism, October 2013, Bentham Science Publishers

    Eleonore Fröhlich

  60. Titanium dioxide nanoparticles and the oral uptake-route

    Article • BioNanoMaterials, September 2013, De Gruyter

    Eleonore Fröhlich

  61. In Vitro and In Vivo Techniques to Assess Neurotoxicity of Nanoparticles

    Article • July 2013, Taylor & Francis

    Eleonore Fröhlich

  62. The oral cavity as a biological barrier system: Design of an advanced buccal in vitro permeability model

    Article • European Journal of Pharmaceutics and Biopharmaceutics, June 2013, Elsevier

    Eleonore Fröhlich

  63. Assessment of Long-Term Effects of Nanoparticles in a Microcarrier Cell Culture System

    Article • PLoS ONE, February 2013, PLOS

    Eleonore Fröhlich

  64. Comparison of two in vitro systems to assess cellular effects of nanoparticles-containing aerosols

    Article • Toxicology in Vitro, February 2013, Elsevier

    Eleonore Fröhlich

  65. Suitability of Cell-Based Label-Free Detection for Cytotoxicity Screening of Carbon Nanotubes

    Article • BioMed Research International, January 2013, Hindawi Publishing Corporation

    Eleonore Fröhlich

  66. New Diagnostic and Therapeutic Tools for Thyroid Cancer

    Article • International Journal of Endocrinology, January 2013, Hindawi Publishing Corporation

    Eleonore Fröhlich

  67. The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles

    Article • International Journal of Nanomedicine, November 2012, Taylor & Francis

    Eleonore Fröhlich

  68. In‐Vitro Permeability of Neutral Polystyrene Particles via Buccal Mucosa

    Article • Small, October 2012, Wiley

    Eleonore Fröhlich

  69. Combination of small size and carboxyl functionalisation causes cytotoxicity of short carbon nanotubes

    Article • Nanotoxicology, October 2012, Taylor & Francis

    Eleonore Fröhlich

  70. Nanoparticles in Biology and Medicine: Methods and Protocols. Edited by Mikhail Soloviev.

    Article • ChemMedChem, October 2012, Wiley

    Eleonore Fröhlich

  71. Interspecies differences in membrane-associated protease activities of thyrocytes and their relevance for thyroid cancer studies

    Article • Journal of Experimental & Clinical Cancer Research, May 2012, Springer Science + Business Media

    Eleonore Fröhlich

  72. Chemical coupling of thiolated chitosan to preformed liposomes improves mucoadhesive properties

    Article • International Journal of Nanomedicine, May 2012, Taylor & Francis

    Eleonore Fröhlich

  73. Differentiation Therapy in Thyroid Carcinoma

    Article • March 2012, IntechOpen

    Eleonore Fröhlich

  74. Models for oral uptake of nanoparticles in consumer products

    Article • Toxicology, January 2012, Elsevier

    Eleonore Fröhlich

  75. Action of polystyrene nanoparticles of different sizes on lysosomal function and integrity

    Article • Particle and Fibre Toxicology, January 2012, Springer Science + Business Media

    Eleonore Fröhlich

  76. Do antidiabetic medications play a specific role in differentiated thyroid cancer compared to other cancer types?

    Article • Diabetes Obesity and Metabolism, November 2011, Wiley

    Eleonore Fröhlich

  77. Globular domain of adiponectin: promising target molecule for detection of atherosclerotic lesions

    Article • Biologics Targets & Therapy, September 2011, Taylor & Francis

    Eleonore Fröhlich

  78. Cytotoxity of nanoparticles is influenced by size, proliferation and embryonic origin of the cells used for testing

    Article • Nanotoxicology, May 2011, Taylor & Francis

    Eleonore Fröhlich

  79. Evaluation of a physiologicalin vitrosystem to study the transport of nanoparticles through the buccal mucosa

    Article • Nanotoxicology, May 2011, Taylor & Francis

    Eleonore Fröhlich

  80. Fibulin-5 mutations link inherited neuropathies, age-related macular degeneration and hyperelastic skin

    Article • Brain, May 2011, Oxford University Press (OUP)

    Prof. Herbert Budka, Eleonore Fröhlich

  81. Pro-angiogenic induction of myeloid cells for therapeutic angiogenesis can induce mitogen-activated protein kinase p38-dependent foam cell formation

    Article • Cytotherapy, April 2011, Elsevier

    Eleonore Fröhlich

  82. Decrease in Dipeptidyl Peptidase IV Activity is Linked to the Efficacy of Differentiating Compounds in Follicular Thyroid Carcinoma Cell Lines

    Article • Hormone and Metabolic Research, March 2011, Thieme Publishing Group

    Eleonore Fröhlich

  83. EP4 receptor stimulation down-regulates human eosinophil function

    Article • Cellular and Molecular Life Sciences, March 2011, Springer Science + Business Media

    Eleonore Fröhlich

  84. Targeted High-Throughput Sequencing Identifies Mutations in atlastin-1 as a Cause of Hereditary Sensory Neuropathy Type I

    Article • The American Journal of Human Genetics, January 2011, Elsevier

    Eleonore Fröhlich

  85. Cholesteryl ester hydrolase activity is abolished in HSL macrophages but unchanged in macrophages lacking KIAA1363

    Article • Journal of Lipid Research, October 2010, Elsevier

    Eleonore Fröhlich

  86. Proteases in cutaneous malignant melanoma: relevance as biomarker and therapeutic target

    Article • Cellular and Molecular Life Sciences, August 2010, Springer Science + Business Media

    Eleonore Fröhlich

  87. Albumin-based nanoparticles as magnetic resonance contrast agents: II. Physicochemical characterisation of purified and standardised nanoparticles

    Article • Histochemistry and Cell Biology, July 2010, Springer Science + Business Media

    Eleonore Fröhlich

  88. Efficient Phagocytosis Requires Triacylglycerol Hydrolysis by Adipose Triglyceride Lipase

    Article • Journal of Biological Chemistry, June 2010, Elsevier

    Eleonore Fröhlich

  89. Proliferation analysis of the growth plate after diaphyseal midshaft fracture by 5′-bromo-2′-deoxy-uridine

    Article • Virchows Archiv, May 2010, Springer Science + Business Media

    Eleonore Fröhlich

  90. The Neuron: The Basis for Processing and Propagation of Information in The Nervous System

    Article • NeuroQuantology, April 2010, NeuroQuantology Journal

    Eleonore Fröhlich

  91. Albumin-based nanoparticles as magnetic resonance contrast agents: I. Concept, first syntheses and characterisation

    Article • Histochemistry and Cell Biology, February 2010, Springer Science + Business Media

    Eleonore Fröhlich

  92. Size-dependent effects of nanoparticles on the activity of cytochrome P450 isoenzymes

    Article • Toxicology and Applied Pharmacology, February 2010, Elsevier

    Eleonore Fröhlich

  93. Chitosan-4-mercaptobenzoic acid: synthesis and characterization of a novel thiolated chitosan

    Article • Journal of Materials Chemistry, January 2010, Royal Society of Chemistry

    Eleonore Fröhlich

  94. Alterations in the ankyrin domain of TRPV4 cause congenital distal SMA, scapuloperoneal SMA and HMSN2C

    Article • Nature Genetics, December 2009, Springer Science + Business Media

    Eleonore Fröhlich

  95. Chitosan-graft-6-mercaptonicotinic Acid: Synthesis, Characterization, and Biocompatibility

    Article • Biomacromolecules, November 2009, American Chemical Society (ACS)

    Eleonore Fröhlich

  96. Postpolymerization modification of poly(pentafluorophenyl methacrylate): Synthesis of a diverse water‐soluble polymer library

    Article • Journal of Polymer Science Part A Polymer Chemistry, July 2009, Wiley

    Eleonore Fröhlich, Dr Matthew Ian Gibson

  97. Efficiency of various dissociation methods for the preparation of thyroid single cell suspensions

    Article • Experimental and Clinical Endocrinology & Diabetes, July 2009, Thieme Publishing Group

    Eleonore Fröhlich

  98. The role of nanoparticle size in hemocompatibility

    Article • Toxicology, April 2009, Elsevier

    Eleonore Fröhlich

  99. Dipeptidyl peptidase II is not a marker for progression in melanoma

    Article • Journal of Dermatological Science, January 2009, Elsevier

    Eleonore Fröhlich

  100. Cytotoxicity of nanoparticles independent from oxidative stress

    Article • The Journal of Toxicological Sciences, January 2009, Japanese Society of Toxicology

    Eleonore Fröhlich

  101. Induction of iodide uptake in transformed thyrocytes: a compound screening in cell lines

    Article • European Journal of Nuclear Medicine, December 2008, Springer Science + Business Media

    Eleonore Fröhlich

  102. Chondrocyte apoptosis enhanced at the growth plate: a physeal response to a diaphyseal fracture

    Article • Cell and Tissue Research, December 2008, Springer Science + Business Media

    Eleonore Fröhlich

  103. Antitumor Effects of Arsenic Trioxide in Transformed Human Thyroid Cells

    Article • Thyroid, November 2008, Mary Ann Liebert Inc

    Eleonore Fröhlich

  104. Hemocompatibility of various nanoparticles in human blood

    Article • Toxicology Letters, October 2008, Elsevier

    Eleonore Fröhlich

  105. Is transketolase like 1 a target for the treatment of differentiated thyroid carcinoma? A study on thyroid cancer cell lines

    Article • Investigational New Drugs, September 2008, Springer Science + Business Media

    Eleonore Fröhlich

  106. Distribution and colocalization of markers for proliferation, invasion, motility and neoangiogenesis in benign melanocytic naevi and malignant melanomas

    Article • British Journal of Dermatology, December 2005, Oxford University Press (OUP)

    Eleonore Fröhlich

  107. Action of thiazolidinediones on differentiation, proliferation and apoptosis of normal and transformed thyrocytes in culture

    Article • Endocrine Related Cancer, June 2005, Bioscientifica

    Eleonore Fröhlich

  108. Retinol has specific effects on binding of thyrotrophin to cultured porcine thyrocytes

    Article • Journal of Endocrinology, December 2004, Bioscientifica

    Eleonore Fröhlich

  109. Cathepsins in basal cell carcinomas: activity, immunoreactivity and mRNA staining of cathepsins B, D, H and L

    Article • Archives of Dermatological Research, June 2004, Springer Science + Business Media

    Eleonore Fröhlich

  110. Cathepsins in basal cell carcinomas: activity, immunoreactivity and mRNA staining of cathepsins B, D, H and L

    Article • Archives of Dermatological Research, February 2004, Springer Science + Business Media

    Eleonore Fröhlich

  111. Proteases in malignant tumors

    Article • DMW - Deutsche Medizinische Wochenschrift, February 2004, Thieme Publishing Group

    Eleonore Fröhlich

  112. Regional differences and post-mortem stability of enzymatic activities in the retinal pigment epithelium

    Article • Graefe s Archive for Clinical and Experimental Ophthalmology, May 2003, Springer Science + Business Media

    Eleonore Fröhlich

  113. Activity, expression, and transcription rate of the cathepsins B, D, H, and L in cutaneous malignant melanoma

    Article • Cancer, March 2001, Wiley

    Eleonore Fröhlich

  114. Mammalian Bax triggers apoptotic changes in yeast

    Article • FEBS Letters, October 1998, Wiley

    Eleonore Fröhlich

  115. Development of multibank rod retinae in deep-sea fishes

    Article • Visual Neuroscience, March 1998, Cambridge University Press

    Eleonore Fröhlich

  116. Rod Outer Segment Renewal in the Retinae of Deep-sea Fish

    Article • Vision Research, October 1996, Elsevier

    Eleonore Fröhlich

  117. Basal lamina formation by porcine thyroid cells grown in collagen- and laminin-deficient medium

    Article • The Histochemical Journal, August 1995, Springer Science + Business Media

    Eleonore Fröhlich

  118. Basal lamina formation by porcine thyroid cells grown in collagen- and laminin-deficient medium

    Article • The Histochemical Journal, August 1995, Springer Science + Business Media

    Eleonore Fröhlich

  119. Patterns of rod proliferation in deep-sea fish retinae

    Article • Vision Research, July 1995, Elsevier

    Eleonore Fröhlich

  120. The occurrence of dopaminergic interplexiform cells correlates with the presence of cones in the retinae of fish

    Article • Visual Neuroscience, March 1995, Cambridge University Press

    Eleonore Fröhlich

  121. Mammalian Müller (glial) cells express functional D2 dopamine receptors

    Article • Neuroreport, March 1995, Wolters Kluwer Health

    Eleonore Fröhlich