What is it about?
Tissues made from stem cells tend to function like fetal, not adult tissues. These tissues are usually grown in constant environments. Our research shows that introducing feeding-fasting rhythms can further the functional specialization, or "maturation" of stem-cell derived islets.
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Why is it important?
It suggests a general mechanism to further maturity of stem-cell derived products.
Read the Original
This page is a summary of: Organoid Maturation by Circadian Entrainment, StemJournal, October 2020, IOS Press,
DOI: 10.3233/stj-209001.
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