Biomarkers and Brain Regions Linked to Cognitive Decline in Alzheimer's Disease

What is it about?

In this study, we investigated the potential of an interdisciplinary approach to predict cognitive scores in AD by utilizing nine multimodal neuroimaging biomarkers. Our proposed prediction model achieved this goal by identifying the most associated biomarkers, especially in the early stages of the disease, and mapping their importance to specific brain regions.

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Why is it important?

The findings highlight the importance of an interdisciplinary approach to understanding the underlying mechanisms of AD and may help in the development of more effective treatments.