What is it about?

Delirium (confusional syndrome) is an acute impairment of consciousness that presents as response of the brain to a diverse range of medical, surgical and pharmacological conditions. We aimed to evaluate whether the phenotype (clinical characteristics) of delirium differs among demographic groups (age at 65 years cutoff and sex) in patients from different countries.

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Why is it important?

Description of clinical characteristics of this syndrome, according to important demographic variables, like age (non-geriatric or geriatric) and sex, is important for clinicians and researchers.

Perspectives

We found that males had higher scores on motor agitation and affective lability (behavioral), whereas females had a higher frequency of hypoactive delirium, and as overall finding, the main clinical alterations (domains) of delirium, cognitive, higher order thinking, and circadian, were present with minor differences in all four demographical groups. Finally, though the influence of a variety of active diagnoses on delirium was small and complex, traumatic brain injury had a clear influence on cognitive characteristics and abrupt onset.

Professor JOSE G FRANCO
Universidad Pontificia Bolivariana

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This page is a summary of: Delirium Phenotype by Age and Sex in a Pooled Data Set of Adult Patients, Journal of Neuropsychiatry, October 2018, American Psychiatric Association,
DOI: 10.1176/appi.neuropsych.18020024.
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